Wolfgang Otto

Summary

Affiliation: University of Regensburg
Country: Germany

Publications

  1. pmc Photodynamic diagnosis for superficial bladder cancer: do all risk-groups profit equally from oncological and economic long-term results?
    Wolfgang Otto
    Department of Urology, University of Regensburg, Germany
    Clin Med Oncol 3:53-8. 2009
  2. pmc Giant scrotal elephantiasis of inflammatory etiology: a case report
    Stefan Denzinger
    Department of Urology, University of Regensburg, Landshuterstraße 65, 93053 Regensburg, Germany
    J Med Case Reports 1:23. 2007
  3. pmc Spontaneous ventral urethral fistula in a young diabetic man: a case report
    Stefan Denzinger
    Department of Urology, University of Regensburg, St, Josef s Hospital, Landshuterstr, 65, 93053 Regensburg, Germany
    J Med Case Reports 1:80. 2007
  4. doi request reprint Gender-specific differences in cancer-specific survival after radical cystectomy for patients with urothelial carcinoma of the urinary bladder in pathologic tumor stage T4a
    Matthias May
    Department of Urology, St Elisabeth Klinikum, Straubing, Germany
    Urol Oncol 31:1141-7. 2013
  5. doi request reprint Gender-dependent cancer-specific survival following radical cystectomy
    Matthias May
    Department of Urology, St Elisabeth Hospital, Straubing, Germany
    World J Urol 30:707-13. 2012
  6. doi request reprint Macroscopic sessile tumor architecture is a pathologic feature of biologically aggressive upper tract urothelial carcinoma
    Hans Martin Fritsche
    Caritas St Josef Medical Center, University of Regensburg, Regensburg, Germany
    Urol Oncol 30:666-72. 2012
  7. doi request reprint Analysis of sex differences in cancer-specific survival and perioperative mortality following radical cystectomy: results of a large German multicenter study of nearly 2500 patients with urothelial carcinoma of the bladder
    Wolfgang Otto
    Department of Urology, Caritas St Josef Medical Centre, University of Regensburg, Landshuterstrasse 65, Regensburg, Germany
    Gend Med 9:481-9. 2012
  8. doi request reprint Serine threonine kinase 15 amplification in normal urothelium of cystectomy specimens is no prognostic factor in urothelial carcinoma of the bladder
    Wolfgang Otto
    Department of Urology, University of Regensburg, Caritas St Josef Medical Centre, Landshuterstraße 65, 93053 Regensburg, Germany
    Pathol Res Pract 207:161-3. 2011
  9. doi request reprint The WHO classification of 1973 is more suitable than the WHO classification of 2004 for predicting survival in pT1 urothelial bladder cancer
    Wolfgang Otto
    Department of Urology, University of Regensburg, Regensburg, Erlangen, Germany
    BJU Int 107:404-8. 2011
  10. doi request reprint Prognostic value of histopathological tumour growth patterns at the invasion front of T1G3 urothelial carcinoma of the bladder
    Stefan Denzinger
    Department of Urology, University of Regensburg, Regensburg, Germany
    Scand J Urol Nephrol 43:282-7. 2009

Collaborators

Detail Information

Publications33

  1. pmc Photodynamic diagnosis for superficial bladder cancer: do all risk-groups profit equally from oncological and economic long-term results?
    Wolfgang Otto
    Department of Urology, University of Regensburg, Germany
    Clin Med Oncol 3:53-8. 2009
    ..The follow-up period is the longest reported to date. As costs might be reimbursed by prolonged recurrence-free survival in certain patients cost analysis in regard to risk-groups was performed...
  2. pmc Giant scrotal elephantiasis of inflammatory etiology: a case report
    Stefan Denzinger
    Department of Urology, University of Regensburg, Landshuterstraße 65, 93053 Regensburg, Germany
    J Med Case Reports 1:23. 2007
    ..Scrotal lymphedema is rare outside endemic filariasis regions in Africa and Asia. It is of variable origin in the western world...
  3. pmc Spontaneous ventral urethral fistula in a young diabetic man: a case report
    Stefan Denzinger
    Department of Urology, University of Regensburg, St, Josef s Hospital, Landshuterstr, 65, 93053 Regensburg, Germany
    J Med Case Reports 1:80. 2007
    ..In a follow-up period of 40 months no recurrence occurred. Spontaneous diabetes-associated ventral urethral fistulas are extremely rare and we are not aware of any other published case report...
  4. doi request reprint Gender-specific differences in cancer-specific survival after radical cystectomy for patients with urothelial carcinoma of the urinary bladder in pathologic tumor stage T4a
    Matthias May
    Department of Urology, St Elisabeth Klinikum, Straubing, Germany
    Urol Oncol 31:1141-7. 2013
    ..Bladder cancer (UCB) staged pT4a show heterogeneous outcome after radical cystectomy (RC). No risk model has been established to date. Despite gender-specific differences, no comparative studies exist for this tumor stage...
  5. doi request reprint Gender-dependent cancer-specific survival following radical cystectomy
    Matthias May
    Department of Urology, St Elisabeth Hospital, Straubing, Germany
    World J Urol 30:707-13. 2012
    ....
  6. doi request reprint Macroscopic sessile tumor architecture is a pathologic feature of biologically aggressive upper tract urothelial carcinoma
    Hans Martin Fritsche
    Caritas St Josef Medical Center, University of Regensburg, Regensburg, Germany
    Urol Oncol 30:666-72. 2012
    ..We tested whether macroscopic tumor architecture improves outcome prediction in an international cohort of patients...
  7. doi request reprint Analysis of sex differences in cancer-specific survival and perioperative mortality following radical cystectomy: results of a large German multicenter study of nearly 2500 patients with urothelial carcinoma of the bladder
    Wolfgang Otto
    Department of Urology, Caritas St Josef Medical Centre, University of Regensburg, Landshuterstrasse 65, Regensburg, Germany
    Gend Med 9:481-9. 2012
    ..Although overall incidence is higher in men, cancer-specific survival (CSS) has been suggested to be lower in women. Although the former effect is attributed to greater exposure to carcinogens in men, the latter has not been elucidated...
  8. doi request reprint Serine threonine kinase 15 amplification in normal urothelium of cystectomy specimens is no prognostic factor in urothelial carcinoma of the bladder
    Wolfgang Otto
    Department of Urology, University of Regensburg, Caritas St Josef Medical Centre, Landshuterstraße 65, 93053 Regensburg, Germany
    Pathol Res Pract 207:161-3. 2011
    ..In contrast to the preceding study, the present data show no STK15 gene amplification in normal urothelium of cystectomy specimens. Prediction of the oncological outcome warrants further research of different markers...
  9. doi request reprint The WHO classification of 1973 is more suitable than the WHO classification of 2004 for predicting survival in pT1 urothelial bladder cancer
    Wolfgang Otto
    Department of Urology, University of Regensburg, Regensburg, Erlangen, Germany
    BJU Int 107:404-8. 2011
    ..To ascertain which of the currently defined World Health Organization (WHO) grading classifications of pT1 urothelial bladder cancer (BC), published in 1973 and 2004, is more suitable for predicting outcome...
  10. doi request reprint Prognostic value of histopathological tumour growth patterns at the invasion front of T1G3 urothelial carcinoma of the bladder
    Stefan Denzinger
    Department of Urology, University of Regensburg, Regensburg, Germany
    Scand J Urol Nephrol 43:282-7. 2009
    ..The aim of this study was to evaluate this aspect in a series of primary T1G3 BC...
  11. ncbi request reprint Prognostic value of perinodal lymphovascular invasion following radical cystectomy for lymph node-positive urothelial carcinoma
    Hans Martin Fritsche
    Department of Urology, Caritas St Josef Medical Centre, University of Regensburg, Germany
    Eur Urol 63:739-44. 2013
    ..Perinodal lymphovascular invasion (pnLVI) has not yet been defined...
  12. doi request reprint External validation of a risk model to predict recurrence-free survival after radical cystectomy in patients with pathological tumor stage T3N0 urothelial carcinoma of the bladder
    Matthias May
    Department of Urology, St Elisabeth Klinikum, Straubing, Germany
    J Urol 187:1210-4. 2012
    ..We present what is to our knowledge the first external validation of this risk model...
  13. ncbi request reprint Predicting individual outcomes after radical cystectomy: an external validation of current nomograms
    Dirk Zaak
    Department of Urology, Ludwig Maximilians Universitat Munchen, Munich, Germany
    BJU Int 106:342-8. 2010
    ....
  14. doi request reprint Multicolor FISH (UroVysion) facilitates follow-up of patients with high-grade urothelial carcinoma of the bladder
    Hans Martin Fritsche
    Dept of Urology, University Regensburg, Caritas Hospital St Josef, Landshuter Straße 65, 93053 Regensburg, Germany
    Am J Clin Pathol 134:597-603. 2010
    ..UroVysion is a worthwhile approach in patients with previous CIS, a high risk for the development of CIS, or previous unequivocal cytology suggestive of CIS, especially during or shortly after instillation therapy...
  15. ncbi request reprint Does preoperative platelet count and thrombocytosis play a prognostic role in patients undergoing nephrectomy for renal cell carcinoma? Results of a comprehensive retrospective series
    Sabine Brookman-May
    Department of Urology, Ludwig Maximilians University Munich, Klinikum Grosshadern, Munich, Germany
    World J Urol 31:1309-16. 2013
    ....
  16. ncbi request reprint Bladder sparing approach for initial T1G3 bladder cancer: Do multifocality, size of tumor or concomitant carcinoma in situ matter? A long-term analysis of 132 patients
    Stefan Denzinger
    Department of Urology, University of Regensburg, Landshuterstrasse 65, Regensburg, Germany
    Int J Urol 14:995-9; discussion 999. 2007
    ..The aim was to determine if they influence the outcome in the bladder sparing approach for initial T1G3 bc...
  17. doi request reprint Concomitant carcinoma in situ as an independent prognostic parameter for recurrence and survival in upper tract urothelial carcinoma: a multicenter analysis of 772 patients
    Wolfgang Otto
    Caritas St Josef Medical Center, University of Regensburg, Regensburg, Germany
    World J Urol 29:487-94. 2011
    ....
  18. doi request reprint Water-jet-aided transurethral dissection of urothelial carcinoma: a prospective clinical study
    Hans Martin Fritsche
    Department of Urology, University of Regensburg, Caritas St Josef Medical Center, Regensburg, Germany
    J Endourol 25:1599-603. 2011
    ..We present the first prospective clinical trial on the application of a combined water-jet dissector and needle-knife (HybridKnife) in transurethral dissection (TUD) of urothelial carcinoma of the bladder (UCB)...
  19. doi request reprint Hexaminolevulinate is equal to 5-aminolevulinic acid concerning residual tumor and recurrence rate following photodynamic diagnostic assisted transurethral resection of bladder tumors
    Maximilian Burger
    Department of Urology, Caritas St Josef Medical Center, University of Regensburg, Regensburg, Germany
    Urology 74:1282-6. 2009
    ..Although numerous and specific data exist on the older substance ALA, considerably less are available on hex, the only agent approved however. To date no such report has been published...
  20. ncbi request reprint Does photodynamic transurethral resection of bladder tumour improve the outcome of initial T1 high-grade bladder cancer? A long-term follow-up of a randomized study
    Stefan Denzinger
    Department of Urology, University of Regensburg, Regensburg, Germany
    BJU Int 101:566-9. 2008
    ..To evaluate, in a long-term follow-up of T1 high-grade bladder cancer treated in a prospective, randomized trial, whether fluorescence diagnosis (FD) increases recurrence-free survival (RFS) or reduces progression to muscle-invasive stages...
  21. doi request reprint Multicenter evaluation of the prognostic value of pT0 stage after radical cystectomy due to urothelial carcinoma of the bladder
    Matthias May
    Department of Urology, St Elisabeth Klinikum, Straubing LMU München, Munchen, Germany
    BJU Int 108:E278-83. 2011
    ..To evaluate the characteristics and long-term outcome of patients with pT0 stage after radical cystectomy (RC) for urothelial carcinoma of the urinary bladder (UCB)...
  22. pmc Sporadic renal cell carcinoma in young and elderly patients: are there different clinicopathological features and disease specific survival rates?
    Stefan Denzinger
    Department of Urology, University of Regensburg, Regensburg, Germany
    World J Surg Oncol 5:16. 2007
    ..In the present retrospective study we reviewed clinicopathological features and disease specific survival rates in young patients (<= 45 years) with RCC and compared them to old patients (>= 75 years) with RCC...
  23. pmc Vacuum-assisted closure therapy in ureteroileal anastomotic leakage after surgical therapy of bladder cancer
    Stefan Denzinger
    Department of Urology, University of Regensburg, Regensburg, Germany
    World J Surg Oncol 5:41. 2007
    ..Vacuum-assisted closure (VAC) is an acknowledged method of treating wound healing disorders, but has been viewed as a contraindication in therapy of intraabdominal fistulas...
  24. doi request reprint Ki-67, mini-chromosome maintenance 2 protein (MCM2) and geminin have no independent prognostic relevance for cancer-specific survival in surgically treated squamous cell carcinoma of the penis
    Matthias May
    Department of Urology, St Elisabeth Clinic Straubing, Straubing, Germany
    BJU Int 112:E383-90. 2013
    ....
  25. doi request reprint The enlightenment of bladder cancer treatment: origin and progress of photodynamic diagnosis
    Wolfgang Otto
    St Josef Medical Centre, Department of Urology of Regensburg University, Landshuterstraße 65, 93053 Regensburg, Germany wolfgang otto klinik uni regensburg de
    Future Oncol 7:1057-66. 2011
    ..This article gives an up-to-date review of the method, indication and results of photodynamic diagnosis for treatment of urothelial bladder cancer...
  26. doi request reprint Characteristics and outcomes of patients with clinical T1 grade 3 urothelial carcinoma treated with radical cystectomy: results from an international cohort
    Hans Martin Fritsche
    Caritas St Josef Medical Centre, University of Regensburg, Regensburg, Germany
    Eur Urol 57:300-9. 2010
    ..Management of T1 grade 3 (T1G3) urothelial carcinoma of the bladder (UCB), with its variable behaviour, represents one of the most difficult challenges for urologists and patients alike...
  27. pmc Neuroendocrine carcinoma of the seminal vesicles presenting with Lambert Eaton syndrome: a case report
    Benedikt Kreiner
    Department of Urology, University of Regensburg, Germany
    J Med Case Reports 4:320. 2010
    ..Primary tumors of seminal vesicles are rare and only a few cases have been reported. Diagnosis is difficult due to the absence of early clinical signs. Prognosis is generally poor...
  28. pmc Collecting duct carcinomas represent a unique tumor entity based on genetic alterations
    Frank Becker
    Department of Urology, University of the Saarland, Homburg Saar, Germany Urological Group Practice and Clinic Derouet Pönicke Becker, Boxberg Center, Neunkirchen, Germany for the German Network of Renal Cell Tumors, Jena, Germany
    PLoS ONE 8:e78137. 2013
    ..CDCs are characterized by a different genetic pattern compared to UUT-UC. Regarding the published data on renal cell carcinoma, we conclude that CDC appears to be a unique entity among kidney carcinomas. ..
  29. ncbi request reprint Early versus deferred cystectomy for initial high-risk pT1G3 urothelial carcinoma of the bladder: do risk factors define feasibility of bladder-sparing approach?
    Stefan Denzinger
    Department of Urology, University of Regensburg, Regensburg, Germany
    Eur Urol 53:146-52. 2008
    ..The aim of this study was to compare survival rates and to analyse the influence of the recognised risk factors multifocality, tumour size, and carcinoma in situ (CIS) in initial transurethral resection of the bladder...
  30. doi request reprint No mutations of FGFR3 in normal urothelium in the vicinity of urothelial carcinoma of the bladder harbouring activating FGFR3 mutations in patients with bladder cancer
    Wolfgang Otto
    Department of Urology, University of Regensburg, Regensburg, Germany
    Int J Cancer 125:2205-8. 2009
    ..Chromosomal alterations like deletions on chromosome 9q or aberrant promoter hypermethylation could play more important roles in early urothelial transformation than mutational FGFR3 activation...
  31. doi request reprint Prognostic factors of papillary renal cell carcinoma: results from a multi-institutional series after pathological review
    Edwin Herrmann
    Department of Urology, University of Munster, Munster, Germany
    J Urol 183:460-6. 2010
    ..We examined papillary renal cell carcinoma prognostic variables and validated the 2002 UICC TNM staging system in a multicenter analysis...
  32. doi request reprint Does sacral neuromodulation lead to relevant reduction in the need for intermittent catheterization? A single-center experience on patients with chronic urinary retention
    Stefan Denzinger
    St Josef Medical Centre, Department of Urology of Regensburg University, Landshuterstraße 65, Regensburg, Germany
    Neuromodulation 15:586-91; discussion 591. 2012
    ..Alongside success in overactive bladder symptoms for detrusor overactivity, SNM also was shown to succeed in chronic urinary retention (UR) of various etiology...
  33. pmc A rare location of metastasis from prostate cancer: hydronephrosis associated with ureteral metastasis
    Sebastian Schneider
    Department of Urology, St Joseph s Mecial Center, University of Regensburg, Landshuter Straße 65, 93053 Regensburg, Germany
    Adv Urol 2012:656023. 2012
    ..Antihormonal treatment led to disappearance of the hydronephrosis; however, further progress finally ended in acute liver failure with patient's death in July 2010...