Christian Otte

Summary

Affiliation: University of Hamburg
Country: Germany

Publications

  1. ncbi request reprint Prolactin but not ACTH increases during sodium lactate-induced panic attacks
    Christian Otte
    University Hospital Hamburg Eppendorf, Department of Psychiatry and Psychotherapy, Martinistrasse 52, 20246, Germany
    Psychiatry Res 109:201-5. 2002
  2. pmc Incomplete remission in depression: role of psychiatric and somatic comorbidity
    Christian Otte
    Department of Psychiatry, University Medical Center Hamburg Eppendorf, Germany
    Dialogues Clin Neurosci 10:453-60. 2008
  3. pmc Glucocorticoid receptor gene and depression in patients with coronary heart disease: the Heart and Soul Study-2009 Curt Richter Award Winner
    Christian Otte
    Department of Psychiatry, University Medical Center Hamburg Eppendorf, Germany
    Psychoneuroendocrinology 34:1574-81. 2009
  4. doi request reprint Modulation of the mineralocorticoid receptor as add-on treatment in depression: a randomized, double-blind, placebo-controlled proof-of-concept study
    Christian Otte
    Department of Psychiatry and Psychotherapy, University Hospital Hamburg Eppendorf, Germany
    J Psychiatr Res 44:339-46. 2010
  5. ncbi request reprint Association between childhood trauma and catecholamine response to psychological stress in police academy recruits
    Christian Otte
    Department of Psychiatry, University of California San Francisco, and Veterans Affairs Medical Center, San Francisco, CA, USA
    Biol Psychiatry 57:27-32. 2005
  6. ncbi request reprint Mineralocorticoid receptor function in posttraumatic stress disorder after pretreatment with metyrapone
    Christian Otte
    Department of Psychiatry and Psychotherapy, University Hospital Hamburg Eppendorf, Martinistrasse 52, Hamburg, Germany
    Biol Psychiatry 60:784-7. 2006
  7. ncbi request reprint A meta-analysis of cortisol response to challenge in human aging: importance of gender
    Christian Otte
    Department of Psychiatry, University of California, San Francisco, CA, USA
    Psychoneuroendocrinology 30:80-91. 2005
  8. pmc Association of a serotonin transporter polymorphism (5-HTTLPR) with depression, perceived stress, and norepinephrine in patients with coronary disease: the Heart and Soul Study
    Christian Otte
    Department of Psychiatry and Psychotherapy, University Medical Center Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
    Am J Psychiatry 164:1379-84. 2007
  9. ncbi request reprint Blockade of the mineralocorticoid receptor in healthy men: effects on experimentally induced panic symptoms, stress hormones, and cognition
    Christian Otte
    Department of Psychiatry and Psychotherapy, University Hospital Hamburg Eppendorf, Hamburg, Germany
    Neuropsychopharmacology 32:232-8. 2007
  10. ncbi request reprint Mineralocorticoid receptor-mediated inhibition of the hypothalamic-pituitary-adrenal axis in aged humans
    Christian Otte
    Department of Psychiatry and Psychotherapy, University Hospital Hamburg Eppendorf, Hamburg, Germany
    J Gerontol A Biol Sci Med Sci 58:B900-5. 2003

Detail Information

Publications56

  1. ncbi request reprint Prolactin but not ACTH increases during sodium lactate-induced panic attacks
    Christian Otte
    University Hospital Hamburg Eppendorf, Department of Psychiatry and Psychotherapy, Martinistrasse 52, 20246, Germany
    Psychiatry Res 109:201-5. 2002
    ..Prolactin release was significantly elevated (P < 0.05) in panickers compared with non-panickers, whereas ACTH secretion was not activated at all. This differential stress response needs further investigation...
  2. pmc Incomplete remission in depression: role of psychiatric and somatic comorbidity
    Christian Otte
    Department of Psychiatry, University Medical Center Hamburg Eppendorf, Germany
    Dialogues Clin Neurosci 10:453-60. 2008
    ..These findings raise important research and treatment issues regarding the generalizability from randomized controlled trials that to exclude patients tend to exclude patients with comorbidity...
  3. pmc Glucocorticoid receptor gene and depression in patients with coronary heart disease: the Heart and Soul Study-2009 Curt Richter Award Winner
    Christian Otte
    Department of Psychiatry, University Medical Center Hamburg Eppendorf, Germany
    Psychoneuroendocrinology 34:1574-81. 2009
    ..3-9.4, p=0.01). These associations persisted after adjusting for potentially confounding variables. A common GR haplotype was associated with depression in a gene-dosage dependent manner and might be a vulnerability factor for depression...
  4. doi request reprint Modulation of the mineralocorticoid receptor as add-on treatment in depression: a randomized, double-blind, placebo-controlled proof-of-concept study
    Christian Otte
    Department of Psychiatry and Psychotherapy, University Hospital Hamburg Eppendorf, Germany
    J Psychiatr Res 44:339-46. 2010
    ..1, p=0.04). Stimulation of MR with fludrocortisone as adjunct to escitalopram accelerated the response in the group of responders while no effect emerged in the sample as a whole. A larger randomized controlled trial is warranted...
  5. ncbi request reprint Association between childhood trauma and catecholamine response to psychological stress in police academy recruits
    Christian Otte
    Department of Psychiatry, University of California San Francisco, and Veterans Affairs Medical Center, San Francisco, CA, USA
    Biol Psychiatry 57:27-32. 2005
    ..Childhood trauma is a risk factor for anxiety disorders in adulthood. One possible mechanism for this association is an increased neuroendocrine response to stress in adults with a history of childhood trauma...
  6. ncbi request reprint Mineralocorticoid receptor function in posttraumatic stress disorder after pretreatment with metyrapone
    Christian Otte
    Department of Psychiatry and Psychotherapy, University Hospital Hamburg Eppendorf, Martinistrasse 52, Hamburg, Germany
    Biol Psychiatry 60:784-7. 2006
    ..Alterations of mineralocorticoid receptor (MR) mediated negative feedback inhibition of cortisol might contribute to abnormalities of hypothalamic-pituitary adrenal (HPA) activity in posttraumatic stress disorder (PTSD)...
  7. ncbi request reprint A meta-analysis of cortisol response to challenge in human aging: importance of gender
    Christian Otte
    Department of Psychiatry, University of California, San Francisco, CA, USA
    Psychoneuroendocrinology 30:80-91. 2005
    ..Prospective studies should explore whether the higher cortisol response in the elderly is a risk factor for developing neuropsychiatric and medical disorders...
  8. pmc Association of a serotonin transporter polymorphism (5-HTTLPR) with depression, perceived stress, and norepinephrine in patients with coronary disease: the Heart and Soul Study
    Christian Otte
    Department of Psychiatry and Psychotherapy, University Medical Center Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
    Am J Psychiatry 164:1379-84. 2007
    ..Whether the short allele increases risk for depression associated with the stress of a chronic illness has not been established...
  9. ncbi request reprint Blockade of the mineralocorticoid receptor in healthy men: effects on experimentally induced panic symptoms, stress hormones, and cognition
    Christian Otte
    Department of Psychiatry and Psychotherapy, University Hospital Hamburg Eppendorf, Hamburg, Germany
    Neuropsychopharmacology 32:232-8. 2007
    ..The domains of cognitive function that are impaired after blockade of MR in men, that is, selective attention, visuospatial memory, and mental flexibility/set shifting appear to be remarkably similar to those described in animal studies...
  10. ncbi request reprint Mineralocorticoid receptor-mediated inhibition of the hypothalamic-pituitary-adrenal axis in aged humans
    Christian Otte
    Department of Psychiatry and Psychotherapy, University Hospital Hamburg Eppendorf, Hamburg, Germany
    J Gerontol A Biol Sci Med Sci 58:B900-5. 2003
    ..Our results implicate that a decrease in MR-mediated negative feedback contributes to the diminished feedback activity in older humans...
  11. ncbi request reprint The mineralocorticoid receptor agonist, fludrocortisone, inhibits pituitary-adrenal activity in humans after pre-treatment with metyrapone
    Christian Otte
    Department of Psychiatry and Psychotherapy, University Hospital Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
    Life Sci 73:1835-45. 2003
    ..05), whereas no such effect was observed after aldosterone or placebo. These preliminary data suggest that MR are involved in the inhibition of the HPA axis during the circadian nadir of glucocorticoid concentrations in humans...
  12. doi request reprint Changes in cortisol secretion during antidepressive treatment and cognitive improvement in patients with major depression: a longitudinal study
    Kim Hinkelmann
    Department of Psychiatry and Psychotherapy, University Medical Center Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
    Psychoneuroendocrinology 37:685-92. 2012
    ..Here, we longitudinally examined if changes in cortisol secretion during treatment are associated with improvement of cognition...
  13. ncbi request reprint Association between alexithymia and neuroendocrine response to psychological stress in police academy recruits
    Shannon E McCaslin
    PTSD Research Program, University of California, San Francisco, VAMC 4150 Clement Street 116P, San Francisco, CA 94121, USA
    Ann N Y Acad Sci 1071:425-7. 2006
    ..Alexithymia scores were negatively associated with catecholamine response to the video challenge but no association was found between alexithymia scores and cortisol reactivity...
  14. ncbi request reprint Effects of metyrapone on hypothalamic-pituitary-adrenal axis and sleep in women with post-traumatic stress disorder
    Christian Otte
    Department of Psychiatry, University of California, San Francisco, California, USA
    Biol Psychiatry 61:952-6. 2007
    ..We previously reported a diminished delta sleep and hypothalamic-pituitary-adrenal (HPA) response to metyrapone in men with post-traumatic stress disorder (PTSD). In this study, we aimed to extend these findings to women...
  15. pmc Cortisol awakening response prospectively predicts peritraumatic and acute stress reactions in police officers
    Sabra S Inslicht
    PTSD Research Program, San Francisco Veterans Affairs Medical Center, 4150 Clement Street 116P, San Francisco, CA 94121, USA
    Biol Psychiatry 70:1055-62. 2011
    ..However, few studies have prospectively examined the relationships among pre-exposure hypothalamic-pituitary-adrenal activity, acute stress reactions and PTSD...
  16. doi request reprint Glucocorticoid receptor gene, low-grade inflammation, and heart failure: the Heart and Soul study
    Christian Otte
    Department of Psychiatry, University Medical Center, 20246 Hamburg Eppendorf, Germany
    J Clin Endocrinol Metab 95:2885-91. 2010
    ..A common haplotype of the glucocorticoid receptor (GR) gene has been associated with increased susceptibility to coronary heart disease (CHD). Whether this haplotype predisposes to heart failure (HF) is unknown...
  17. ncbi request reprint Hypothalamic-pituitary-adrenal axis activity and sleep in posttraumatic stress disorder
    Christian Otte
    Department of Psychiatry, University of California, San Francisco, CA, USA
    Neuropsychopharmacology 30:1173-80. 2005
    ..Future studies should explore the temporal relationship between HPA activity, sleep disturbances, and psychopathology after a traumatic event...
  18. doi request reprint Cortisol has enhancing, rather than impairing effects on memory retrieval in PTSD
    Katja Wingenfeld
    Department of Psychiatry, Charite University Berlin, Campus Benjamin Franklin, Berlin, Germany
    Psychoneuroendocrinology 37:1048-56. 2012
    ..In healthy participants, administration of cortisol impairs declarative memory retrieval. Only a few studies have investigated these effects in PTSD yielding mixed results...
  19. pmc Pretraumatic prolonged elevation of salivary MHPG predicts peritraumatic distress and symptoms of post-traumatic stress disorder
    Brigitte A Apfel
    Department of Psychiatry, University of California, San Francisco, CA 94121, USA
    J Psychiatr Res 45:735-41. 2011
    ..Prolonged elevation of salivary MHPG in response to a laboratory stressor marks a predisposition to experience higher levels of peritraumatic distress and subsequently more PTSD symptoms following critical incident exposure...
  20. ncbi request reprint No improvement of posttraumatic stress disorder symptoms with guanfacine treatment
    Thomas C Neylan
    Department of Psychiatry, University of California, San Francisco, USA
    Am J Psychiatry 163:2186-8. 2006
    ..The authors report an 8-week, double-blind, randomized controlled trial of guanfacine versus placebo for posttraumatic stress disorder (PTSD)...
  21. ncbi request reprint Overnight metyrapone and combined dexamethasone/metyrapone tests in post-traumatic stress disorder: preliminary findings
    Michael Kellner
    Department of Psychiatry and Psychotherapy, University Hospital Hamburg Eppendorf, Martinistrasse 52, D 20246 Hamburg, Germany
    Eur Neuropsychopharmacol 14:337-9. 2004
    ..Dose-response studies using metyrapone and glucocorticoid agonists are needed to further investigate HPA axis regulation in PTSD...
  22. pmc Serum brain-derived neurotrophic factor predicts responses to escitalopram in chronic posttraumatic stress disorder
    William Berger
    Department of Psychiatry, University of California, San Francisco, CA, USA
    Prog Neuropsychopharmacol Biol Psychiatry 34:1279-84. 2010
    ..Some studies have found that antidepressants increase serum brain-derived neurotrophic factor (BDNF) levels in patients with major depression and the expression of BDNF mRNA in limbic structures of rats...
  23. doi request reprint Sex differences of salivary cortisol secretion in patients with major depression
    Kim Hinkelmann
    Department of Psychiatry and Psychotherapy, University Hospital Hamburg Eppendorf Hamburg, Germany
    Stress 15:105-9. 2012
    ..Study characteristics and methods as well as sex-specific confounding variables such as menstrual cycle, menopause and the use of oral contraceptives may account for inconclusive results across studies...
  24. pmc Depressive symptoms, health behaviors, and risk of cardiovascular events in patients with coronary heart disease
    Mary A Whooley
    VA Medical Center, San Francisco, California, USA
    JAMA 300:2379-88. 2008
    ..Depressive symptoms predict adverse cardiovascular outcomes in patients with coronary heart disease, but the mechanisms responsible for this association are unknown...
  25. pmc Depression and 24-hour urinary cortisol in medical outpatients with coronary heart disease: The Heart and Soul Study
    Christian Otte
    Department of Psychiatry, University of California, Veterans Affairs Medical Center, San Francisco, CA 94121, USA
    Biol Psychiatry 56:241-7. 2004
    ..However, it is not known whether depression is associated with elevated cortisol levels in patients with CHD...
  26. ncbi request reprint Neuroendocrine regulation of sleep disturbances in PTSD
    Thomas C Neylan
    University of California, San Francisco, San Francisco DVAMC 116P, 4150 Clement Street, San Francisco, CA 94121, USA
    Ann N Y Acad Sci 1071:203-15. 2006
    ....
  27. pmc Depressive symptoms and 24-hour urinary norepinephrine excretion levels in patients with coronary disease: findings from the Heart and Soul Study
    Christian Otte
    Department of Psychiatry, University of California, San Francisco, CA 94121, USA
    Am J Psychiatry 162:2139-45. 2005
    ..Elevated catecholamine levels may contribute to this association, but whether depressive symptoms are associated with catecholamine levels in patients with heart disease is unknown...
  28. ncbi request reprint Increased cortisol in women with intimate partner violence-related posttraumatic stress disorder
    Sabra S Inslicht
    Veterans Affairs Medical Center, 4150 Clement Street 116P, San Francisco, CA 94121, USA
    Ann N Y Acad Sci 1071:428-9. 2006
    ..Cortisol was elevated in women with lifetime PTSD compared to controls. No differences were found for platelet catecholamines...
  29. pmc Association between a serotonin transporter gene variant and hopelessness among men in the Heart and Soul Study
    Kirsten Neudoerffer Kangelaris
    Department of Medicine, Division of General Internal Medicine, University of California, San Francisco, San Francisco, CA, USA
    J Gen Intern Med 25:1030-7. 2010
    ....
  30. ncbi request reprint Depression and cortisol responses to psychological stress: a meta-analysis
    Heather M Burke
    Department of Psychiatry, University of California, San Francisco, USA
    Psychoneuroendocrinology 30:846-56. 2005
    ..This blunted reactivity-impaired recovery pattern observed among the afternoon studies was most pronounced in studies with older and more severely depressed patients...
  31. doi request reprint Cognitive impairment in major depression: association with salivary cortisol
    Kim Hinkelmann
    Department of Psychiatry and Psychotherapy, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Biol Psychiatry 66:879-85. 2009
    ..Several studies have separately examined cortisol secretion and cognitive deficits in depression. However, only few studies have assessed their association in the same patients producing inconclusive results...
  32. doi request reprint Depressive symptoms and metabolic risk: effects of cortisol and gender
    Christoph Muhtz
    Department of Psychiatry and Psychotherapy, University Hospital Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
    Psychoneuroendocrinology 34:1004-11. 2009
    ..In women, depressive symptoms are associated with several variables of the metabolic syndrome. Elevated afternoon and evening cortisol appear to partially mediate this association...
  33. ncbi request reprint Predictors of posttraumatic stress in police and other first responders
    Charles R Marmar
    San Francisco Veterans Affairs Medical Center, 4150 Clement St 116 P, San Francisco, CA 94121, USA
    Ann N Y Acad Sci 1071:1-18. 2006
    ..Next steps in this line of research will be to test this model prospectively in a sample of 400 police academy recruits assessed during training and currently being followed for the first 2 years of police service...
  34. doi request reprint Effects of noradrenergic stimulation on memory in patients with major depressive disorder
    Katja Wingenfeld
    Department of Psychiatry, Charite University Berlin, Campus Benjamin Franklin, Eschenallee 3, 14050 Berlin, Germany
    Stress 16:191-201. 2013
    ..The mechanism by which yohimbine leads to stronger memory consolidation in depressed patients compared with healthy controls remains to be elucidated...
  35. doi request reprint Decreased hydrocortisone sensitivity of T cell function in multiple sclerosis-associated major depression
    Anja Fischer
    Institute for Neuroimmunology and Clinical Multiple Sclerosis Research, Center for Molecular Neurobiology, University Hospital Hamburg Eppendorf, Hamburg, Germany
    Psychoneuroendocrinology 37:1712-8. 2012
    ..To our knowledge, this study provides first evidence for altered steroid sensitivity of T cells from MS patients with comorbid MDD possibly due to MR dysregulation...
  36. doi request reprint Association of a common mineralocorticoid receptor gene polymorphism with salivary cortisol in healthy adults
    Christoph Muhtz
    Department of Psychiatry and Psychotherapy, University Hospital Hamburg Eppendorf, Hamburg, Germany
    Psychoneuroendocrinology 36:298-301. 2011
    ..This polymorphism may contribute to the interindividual variability in stress responsiveness and might be involved in stress-related disorders...
  37. ncbi request reprint Delta sleep response to metyrapone in post-traumatic stress disorder
    Thomas C Neylan
    Department of Psychiatry, University of California, USA
    Neuropsychopharmacology 28:1666-76. 2003
    ..The results suggest that the delta sleep response to metyrapone is a measure of the brain response to increases in hypothalamic CRF. These data also suggest that the ACTH and sleep EEG response to hypothalamic CRF is decreased in PTSD...
  38. pmc Depression and whole blood serotonin in patients with coronary heart disease from the Heart and Soul Study
    Lawson R Wulsin
    Department of Psychiatry, University of Cincinnati, Cincinnati, Ohio, USA
    Psychosom Med 71:260-5. 2009
    ..Depression is associated with incident CHD and with adverse cardiovascular outcomes. Dysregulation of peripheral serotonin, common to both depression and CHD, may contribute to this association...
  39. doi request reprint Hair testosterone and visuospatial memory in middle-aged men and women with and without depressive symptoms
    Lucia Dettenborn
    Department of Medical Psychology, University Medical Center Hamburg Eppendorf, Hamburg, Germany Electronic address
    Psychoneuroendocrinology 38:2373-7. 2013
    ..We examined hair testosterone and its association with verbal and visuospatial memory in middle-aged men and women with and without major depression...
  40. doi request reprint Cortisol response to experimental pain in patients with chronic low back pain and patients with major depression
    Christoph Muhtz
    Department of Psychosomatic Medicine and Psychotherapy, University Medical Center Hamburg Eppendorf and Schön Klinik Hamburg Eilbek, Hamburg, Germany
    Pain Med 14:498-503. 2013
    ..However, little is known about the effects of experimentally induced acute pain on cortisol secretion in patients with chronic pain and depression...
  41. doi request reprint Statin use and risk of depression in patients with coronary heart disease: longitudinal data from the Heart and Soul Study
    Christian Otte
    Department of Psychiatry, Campus Benjamin Franklin, Charite University Medical Center, Berlin, Germany
    J Clin Psychiatry 73:610-5. 2012
    ..Statins are among the most commonly prescribed medications worldwide. Although their benefits for cardiovascular disease are well established, the effects of statins on depressive symptoms are unknown...
  42. doi request reprint Childhood trauma in multiple sclerosis: a case-control study
    Carsten Spitzer
    Department of Psychosomatic Medicine and Psychotherapy, University Medical Center Hamburg Eppendorf and Schön Klinik Hamburg Eilbek, Martinistr 52, 20246 Hamburg, Germany
    Psychosom Med 74:312-8. 2012
    ....
  43. doi request reprint Hydrocortisone impairs working memory in healthy humans, but not in patients with major depressive disorder
    Kirsten Terfehr
    Department of Psychosomatic Medicine and Psychotherapy, University Medical Center Hamburg Eppendorf and Schön Klinik Hamburg Eilbek, Hamburg, Germany
    Psychopharmacology (Berl) 215:71-9. 2011
    ..The purpose of our study was to investigate whether the finding of missing effects of acute cortisol administration on memory performance in MDD is also seen when examining prefrontal-based working memory...
  44. doi request reprint Endocrine and immune substrates of depressive symptoms and fatigue in multiple sclerosis patients with comorbid major depression
    Stefan M Gold
    Institute for Neuroimmunology und Clinical Multiple Sclerosis Research inims, Falkenried 94, D 20251 Hamburg, Germany
    J Neurol Neurosurg Psychiatry 82:814-8. 2011
    ..In this study, the relative role of cytokines and hypothalamic-pituitary-adrenal (HPA) axis activity in depression and fatigue were examined in patients with relapsing-remitting MS (RRMS)...
  45. doi request reprint When the half-full glass is appraised as half empty and memorised as completely empty: mood-congruent true and false recognition in depression is modulated by salience
    Steffen Moritz
    University Hospital Hamburg, Germany
    Memory 16:810-20. 2008
    ..In contrast, group differences in recognition performance did not significantly affect salience ratings. Results indicate that salience modulates MCM and may account for discrepancies in the literature...
  46. pmc Cognitive behavioral therapy in anxiety disorders: current state of the evidence
    Christian Otte
    Department of Psychiatry, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Dialogues Clin Neurosci 13:413-21. 2011
    ..In conclusion, CBT appears to be both efficacious and effective in the treatment of anxiety disorders, but more high-quality studies are needed to better estimate the magnitude of the effect...
  47. doi request reprint Immediate and early behavioral interventions for the prevention of acute and posttraumatic stress disorder
    Agorastos Agorastos
    Department of Psychiatry and Psychotherapy, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Curr Opin Psychiatry 24:526-32. 2011
    ..This article aims to review the current evidence regarding immediate (within hours) and early (within days and weeks) psychological and behavioral interventions to prevent posttraumatic stress symptoms...
  48. ncbi request reprint Associations between childhood trauma and emotion-modulated psychophysiological responses to startling sounds: a study of police cadets
    Nnamdi Pole
    Department of Psychology, University of Michigan, Ann Arbor, MI 48109 1043, USA
    J Abnorm Psychol 116:352-61. 2007
    ..Results suggest that childhood trauma may lead to long-lasting alterations in emotional and psychophysiological reactivity even in the absence of current Axis I psychopathology...
  49. ncbi request reprint Increased cortisol in women with intimate partner violence-related posttraumatic stress disorder
    Sabra S Inslicht
    Department of Psychology, University of Pittsburgh Sennott Square, 3rd Floor, 210 S Bouquet Street, Pittsburgh, PA 15260, USA
    Psychoneuroendocrinology 31:825-38. 2006
    ..Alterations of hypothalamic-pituitary-adrenal (HPA) axis function and sympathetic-adrenal activity have been proposed as key factors in biological models of posttraumatic stress disorder (PTSD)...
  50. ncbi request reprint Hypothalamic-pituitary-adrenocortical axis activity: a target of pharmacological anticraving treatment?
    Falk Kiefer
    Department of Addictive Behavior and Addiction Medicine, Central Institute of Mental Health, University of Heidelberg, Mannheim, Germany
    Biol Psychiatry 60:74-6. 2006
    ..We examined the relationship between efficacy of pharmacological anticraving treatment and HPA axis activity in the relapse prevention treatment of alcoholism...
  51. ncbi request reprint Effects of Hatha yoga and African dance on perceived stress, affect, and salivary cortisol
    Jeremy West
    Reed College, USA
    Ann Behav Med 28:114-8. 2004
    ..Dance and yoga have been shown to produce improvements in psychological well-being...
  52. ncbi request reprint Mineralocorticoid receptor function in patients with posttraumatic stress disorder
    Michael Kellner
    Depatment of Psychiatry and Psychotherapy, University Hospital Hamburg Eppendorf, Germany
    Am J Psychiatry 159:1938-40. 2002
    ....
  53. ncbi request reprint Increasing leptin precedes craving and relapse during pharmacological abstinence maintenance treatment of alcoholism
    Falk Kiefer
    Department of Addictive Behaviour and Addiction Medicine, Central Institute of Mental Health CIMH, University of Heidelberg, J5, 68159 Mannheim, Germany
    J Psychiatr Res 39:545-51. 2005
    ..Moreover, there are hints for an interaction between pharmacological anti-craving treatment, plasma concentration of leptin, and abstinence duration...
  54. pmc Association of metabolic syndrome with exercise capacity and heart rate recovery in patients with coronary heart disease in the heart and soul study
    Christian Spies
    Section of Cardiology, Rush University Medical Center, Chicago, Illinois, USA
    Am J Cardiol 95:1175-9. 2005
    ..Decreased exercise capacity may contribute to the adverse outcomes associated with the metabolic syndrome...
  55. ncbi request reprint Valproate monotherapy in the treatment of civilian patients with non-combat-related posttraumatic stress disorder: an open-label study
    Christian Otte
    J Clin Psychopharmacol 24:106-8. 2004
  56. ncbi request reprint Pharmacological relapse prevention of alcoholism: clinical predictors of outcome
    Falk Kiefer
    Department of Addictive Behaviour and Addiction Medicine, Central Institute of Mental Health CIMH, University of Heidelberg, Heidelberg, Germany
    Eur Addict Res 11:83-91. 2005
    ..The efficacy of pharmacological relapse prevention in alcoholism with acamprosate and naltrexone has been supported by several controlled trials. It remains uncertain whether any differential indication for treatment exists...