M Obermann

Summary

Affiliation: University of Duisburg-Essen
Country: Germany

Publications

  1. ncbi request reprint Medication overuse headache
    Mark Obermann
    Department of Neurology, University of Duisburg Essen, Hufelandstr 55, 45122 Essen, Germany
    Expert Opin Drug Saf 5:49-56. 2006
  2. pmc Topiramate in the prevention and treatment of migraine: efficacy, safety and patient preference
    Steffen Naegel
    Department of Neurology, University of Duisburg Essen, Hufelandstr 55, 45122 Essen, Germany
    Neuropsychiatr Dis Treat 6:17-28. 2010
  3. doi request reprint Gray matter volume reduction reflects chronic pain in trigeminal neuralgia
    Mark Obermann
    Department of Neurology, University of Duisburg Essen, Germany
    Neuroimage 74:352-8. 2013
  4. doi request reprint [Chronic dizziness and vertigo from a neurologists' perspective]
    M Obermann
    Klinik für Neurologie und Schwindel Zentrum, Universitatsklinikum Essen
    Dtsch Med Wochenschr 138:269-74. 2013
  5. pmc Erythropoietin overrides the triggering effect of DNA platination products in a mouse model of cisplatin-induced neuropathy
    Min Suk Yoon
    Department of Neurology, University of Duisburg Essen, Essen, Germany
    BMC Neurosci 10:77. 2009
  6. doi request reprint Sensory disinhibition on passive movement in cervical dystonia
    Mark Obermann
    Department of Neurology, University of Duisburg Essen, Essen, Germany
    Mov Disord 25:2627-33. 2010
  7. ncbi request reprint [Acute headache: what you should not at all fail to do]
    M Obermann
    Klinik und Poliklinik fur Neurologie, Universitatsklinikum Essen
    MMW Fortschr Med 150:44-7. 2008
  8. doi request reprint Epidemiology of unilateral headaches
    Mark Obermann
    Department of Neurology, University of Duisburg Essen, Hufelandstr 55, 45122 Essen, Germany
    Expert Rev Neurother 8:1313-20. 2008
  9. doi request reprint Substantia nigra hyperechogenicity and CSF dopamine depletion in HIV
    Mark Obermann
    Department of Neurology, University of Duisburg Essen, Hufelandstr 55, 45122, Essen, Germany
    J Neurol 256:948-53. 2009
  10. doi request reprint Update on trigeminal neuralgia
    Mark Obermann
    Department of Neurology, University of Duisburg Essen, Essen, Germany
    Expert Rev Neurother 9:323-9. 2009

Detail Information

Publications44

  1. ncbi request reprint Medication overuse headache
    Mark Obermann
    Department of Neurology, University of Duisburg Essen, Hufelandstr 55, 45122 Essen, Germany
    Expert Opin Drug Saf 5:49-56. 2006
    ..The only effective treatment concept is consequent withdrawal therapy. Data of prospective studies on relapse rates and predictors of relapse after successful withdrawal therapy are presented...
  2. pmc Topiramate in the prevention and treatment of migraine: efficacy, safety and patient preference
    Steffen Naegel
    Department of Neurology, University of Duisburg Essen, Hufelandstr 55, 45122 Essen, Germany
    Neuropsychiatr Dis Treat 6:17-28. 2010
    ..Topiramate is also effective in treating patients with chronic migraine. It has little pharmacological interaction with other drugs and is generally well tolerated by patients...
  3. doi request reprint Gray matter volume reduction reflects chronic pain in trigeminal neuralgia
    Mark Obermann
    Department of Neurology, University of Duisburg Essen, Germany
    Neuroimage 74:352-8. 2013
    ..The ACC, parahippocampus and temporal lobe volume reduction in parallel with disease duration may point to a pivotal role of these structures in chronic pain...
  4. doi request reprint [Chronic dizziness and vertigo from a neurologists' perspective]
    M Obermann
    Klinik für Neurologie und Schwindel Zentrum, Universitatsklinikum Essen
    Dtsch Med Wochenschr 138:269-74. 2013
    ..The majority of these disorders can be well treated and have an excellent prognosis, when diagnosed adequately and within a reasonable time frame to prevent the development of chronic disease...
  5. pmc Erythropoietin overrides the triggering effect of DNA platination products in a mouse model of cisplatin-induced neuropathy
    Min Suk Yoon
    Department of Neurology, University of Duisburg Essen, Essen, Germany
    BMC Neurosci 10:77. 2009
    ..We investigated in a mouse model by which mechanism recombinant erythropoietin (rhEPO) protects the peripheral nervous system from structural and functional damage caused by cisplatin treatment with special emphasis on DNA damage burden...
  6. doi request reprint Sensory disinhibition on passive movement in cervical dystonia
    Mark Obermann
    Department of Neurology, University of Duisburg Essen, Essen, Germany
    Mov Disord 25:2627-33. 2010
    ..The observed sensory overactivation suggests a general disinhibition of the somatosensory system in CD as it was not limited to the motor-system or the direct neuronal representation of the affected dystonic musculature alone...
  7. ncbi request reprint [Acute headache: what you should not at all fail to do]
    M Obermann
    Klinik und Poliklinik fur Neurologie, Universitatsklinikum Essen
    MMW Fortschr Med 150:44-7. 2008
  8. doi request reprint Epidemiology of unilateral headaches
    Mark Obermann
    Department of Neurology, University of Duisburg Essen, Hufelandstr 55, 45122 Essen, Germany
    Expert Rev Neurother 8:1313-20. 2008
    ..This has led to improved treatment strategies in primary patient care that may prevent prolonged suffering of affected patients in the future...
  9. doi request reprint Substantia nigra hyperechogenicity and CSF dopamine depletion in HIV
    Mark Obermann
    Department of Neurology, University of Duisburg Essen, Hufelandstr 55, 45122, Essen, Germany
    J Neurol 256:948-53. 2009
    ..Our results indicate changes in the nigrostriatal system in HIV-infected patients that are detectable as hyperechogenic SN precede prominent extrapyramidal symptoms and cognitive dysfunction...
  10. doi request reprint Update on trigeminal neuralgia
    Mark Obermann
    Department of Neurology, University of Duisburg Essen, Essen, Germany
    Expert Rev Neurother 9:323-9. 2009
    ..Continuous scientific research works towards a better understanding of trigeminal neuralgia and has accomplished a greater insight into the underlying pathophysiological mechanisms...
  11. doi request reprint Post-traumatic headache
    Mark Obermann
    Department of Neurology, University of Duisburg Essen, Hufelandstrasse 55, 45122 Essen, Germany
    Expert Rev Neurother 9:1361-70. 2009
    ....
  12. doi request reprint Temporal summation of trigeminal pain in human anterior cingulate cortex
    Mark Obermann
    Department of Neurology, University of Duisburg Essen, Hufelandstr 55, 45122 Essen, Germany
    Neuroimage 46:193-200. 2009
    ..These findings indicate that pACC codes temporal summation of trigeminal nociception and in this regard may be important for the development of central sensitization observed in chronic head and facial pain...
  13. doi request reprint Trigeminal neuralgia and persistent idiopathic facial pain
    Mark Obermann
    Department of Neurology, University of Duisburg Essen, Hufelandstr 55, 45122 Essen, Germany
    Expert Rev Neurother 11:1619-29. 2011
    ..The etiology and underlying pathophysiology of TN, and more so PIFP, remain unknown. Treatment is based on only few randomized controlled clinical trials and insufficiently evaluated surgical procedures...
  14. doi request reprint Gray matter changes related to chronic posttraumatic headache
    Mark Obermann
    Department of Neurology, University of Duisburg Essen, 45122 Essen, Germany
    Neurology 73:978-83. 2009
    ..Although up to 15% of patients with whiplash injury develop chronic headache, the basis and mechanisms of this posttraumatic headache are not well understood...
  15. ncbi request reprint Hypnic headache
    Mark Obermann
    Department of Neurology, University of Duisburg Essen, Hufelandstrasse 55, Essen, Germany
    Expert Rev Neurother 10:1391-7. 2010
    ..Lithium, indomethacin and melatonin were promoted as potent medical treatments, while almost every other drug commonly used to treat headache or other pain syndromes was reported to be effective in single case reports on hypnic headache...
  16. doi request reprint Increased basal-ganglia activation performing a non-dystonia-related task in focal dystonia
    M Obermann
    Department of Neurology, University of Duisburg Essen, Essen, Germany
    Eur J Neurol 15:831-8. 2008
    ....
  17. doi request reprint Headache attributable to nonvascular intracranial disorders
    Mark Obermann
    Department of Neurology, University of Duisburg Essen, Hufelandstrasse 55, 45122 Essen, Germany
    Curr Pain Headache Rep 15:314-23. 2011
    ..The clinical presentation of all these disorders can be diverse and often mimics the characteristics of primary headaches, which may delay the diagnosis...
  18. ncbi request reprint Correlation of epidermal nerve fiber density with pain-related evoked potentials in HIV neuropathy
    Mark Obermann
    Department of Neurology, University of Duisburg Essen, Hufelandstr 55, 45122 Essen, Germany
    Pain 138:79-86. 2008
    ..The method of pain-related evoked potential conduction appears to be a sensitive, fast, non-invasive technique for the detection of small-fiber neuropathy and may prove to become a valuable diagnostic asset...
  19. ncbi request reprint Efficacy of pregabalin in the treatment of trigeminal neuralgia
    M Obermann
    Department of Neurology, University of Duisburg Essen, Essen, Germany
    Cephalalgia 28:174-81. 2008
    ..020). Concomitant chronic facial pain appears to be a clinical predictor of poor treatment outcome. PGB appears to be effective in the treatment of trigeminal neuralgia...
  20. ncbi request reprint Management of medication-overuse headache
    Mark Obermann
    University of Duisburg Essen, Department of Neurology, Hufelandstr 55, 45122 Essen, Germany
    Expert Rev Neurother 7:1145-55. 2007
    ..Management of MOH remains difficult; the only effective treatment concept is consequent withdrawal therapy...
  21. ncbi request reprint Migraine with isolated facial pain: a diagnostic challenge
    M Obermann
    Department of Neurology, University of Duisburg Essen, Essen, Germany
    Cephalalgia 27:1278-82. 2007
    ....
  22. ncbi request reprint Impaired trigeminal nociceptive processing in patients with trigeminal neuralgia
    M Obermann
    Department of Neurology, University Duisburg Essen, Essen, Germany
    Neurology 69:835-41. 2007
    ..Between the attacks the patient is usually asymptomatic, but a constant dull background pain may persist in some cases. The mechanisms associated with the development of this chronic pain are not well understood...
  23. ncbi request reprint Morphometric changes of sensorimotor structures in focal dystonia
    Mark Obermann
    Department of Neurology, University of Duisburg Essen, Essen, Germany
    Mov Disord 22:1117-23. 2007
    ..They also demonstrate structural similarities of the investigated focal dystonias, possibly reflecting a shared common pathophysiological origin...
  24. doi request reprint Electrically evoked nociceptive potentials for early detection of diabetic small-fiber neuropathy
    D Mueller
    Department of Neurology, University of Duisburg Essen, Essen, Germany
    Eur J Neurol 17:834-41. 2010
    ....
  25. ncbi request reprint Central sensitization of the trigeminal and somatic nociceptive systems in medication overuse headache mainly involves cerebral supraspinal structures
    I Ayzenberg
    Department of Neurology, University of Essen, Essen, Germany, and Institute of Neurology, The National Hospital for Neurology and Neurosurgery, London, UK
    Cephalalgia 26:1106-14. 2006
    ..A transient facilitation was found of trigeminal and somatic nociceptive systems in MOH, which was more pronounced on a supraspinal level...
  26. doi request reprint Prevalence of facial pain in migraine: a population-based study
    M S Yoon
    Department of Neurology, University of Duisburg Essen, Essen, Germany
    Cephalalgia 30:92-6. 2010
    ..23, P < 0.001). In one case isolated facial pain without headache was the leading symptom of migraine. Our results demonstrate that facial pain is not unusual in migraine, whereas isolated facial migraine is extremely rare...
  27. doi request reprint Lateralized central facilitation of trigeminal nociception in cluster headache
    D Holle
    Department of Neurology, University of Duisburg Essen, Essen, Germany
    Neurology 78:985-92. 2012
    ..To investigate whether central facilitation of trigeminal pain processing is part of the pathophysiology of cluster headache (CH)...
  28. ncbi request reprint Prevalence of cluster headache in a population-based sample in Germany
    Z Katsarava
    Department of Neurology, University Hospital Essen, Essen, Germany
    Cephalalgia 27:1014-9. 2007
    ..7 +/- 12.7 years). All suspected cases (N = 182) were interviewed by a neurologist. Four subjects with CH (three men) were identified. The 1-year prevalence of CH was estimated to be 119/100,000 (95% confidence interval 3, 238/100,000)...
  29. doi request reprint Population-based validation of a German-language self-administered headache questionnaire
    M S Yoon
    Department of Neurology, University of Essen, Hufelandstrasse 55, Essen, Germany
    Cephalalgia 28:605-8. 2008
    ....
  30. doi request reprint Incidence and predictors of chronic headache attributed to whiplash injury
    M Obermann
    Department of Neurology, University of Duisburg Essen, Essen, Germany
    Cephalalgia 30:528-34. 2010
    ..024), and depression (OR 3.3, 95% CI 1.2, 9.4; P = 0.024). The lack of a control group limits the conclusions that can be drawn from this study. Identified predictors closely resemble those found in chronic primary headache disorders...
  31. ncbi request reprint Prevalence of trigeminal autonomic symptoms in migraine: a population-based study
    M Obermann
    Department of Neurology, University of Duisburg Essen, Essen, Germany
    Cephalalgia 27:504-9. 2007
    ..Migraine patients with accompanying autonomic symptoms seem to experience their pain more unilateral and more severe than non-UA patients...
  32. doi request reprint Structural gray and white matter changes in patients with HIV
    Michael Küper
    Department of Neurology, University of Duisburg Essen, Hufelandstr 55, 45122, Essen, Germany
    J Neurol 258:1066-75. 2011
    ..This pattern of atrophy is consistent with motor dysfunction and dysexecutive syndrome found in HIV patients with HIV-associated neurocognitive disorder...
  33. doi request reprint Chronic migraine: classification and comparisons
    Z Katsarava
    Department of Neurology, University of Essen, Hufelandstrasse 55, Essen, Germany
    Cephalalgia 31:520-9. 2011
    ....
  34. pmc Prevalence of primary headaches in Germany: results of the German Headache Consortium Study
    M S Yoon
    Department of Neurology, Ruhr University Bochum, Gudrunstr 56, 44791, Bochum, Germany
    J Headache Pain 13:215-23. 2012
    ..The prevalence with respect to episodic and chronic primary headache disorders in Germany is comparable to other European countries and the USA...
  35. ncbi request reprint Symptomatic migraine and pontine vascular malformation: evidence for a key role of the brainstem in the pathophysiology of chronic migraine
    M Obermann
    Department of Neurology, University Duisburg Essen, Essen, Germany
    Cephalalgia 26:763-6. 2006
  36. ncbi request reprint Recombinant human erythropoietin counteracts cisplatin-induced visceral hyperalgesia
    Min Suk Yoon
    Department of Neurology, University of Duisburg Essen, Essen, Germany
    Neurosci Bull 26:282-8. 2010
    ..The present study was aimed to investigate the effect of recombinant human erythropoietin (rhEPO) on cisplatin-induced visceral hyperalgesia...
  37. doi request reprint Sensory neuropathy in patients with cryoglobulin negative hepatitis-C infection
    Min Suk Yoon
    Department of Neurology, University of Duisburg Essen, Hufelandstrasse 55, 45122, Essen, Germany
    J Neurol 258:80-8. 2011
    ..5%) is higher than previously reported and (4) we found that detection of HCV associated neuropathy depends on the evaluation method...
  38. ncbi request reprint Cavernous malformation with hemorrhage of the conus medullaris and progressive sensory loss
    M Obermann
    Department of Neurology, University Duisburg Essen, Germany
    Clin Neuropathol 25:95-7. 2006
    ..It is essential to achieve complete removal during the first operation to avoid any residues that may lead to further bleeding...
  39. ncbi request reprint Transcranial sonography of the third ventricle and cognitive dysfunction in HIV patients
    Ozgur Yaldizli
    Department of Neurology, University of Duisburg Essen, Hufelandstr 55, Essen 45122, Germany
    J Neurol 253:1185-8. 2006
    ..Previous magnetic resonance imaging (MRI) studies showed a correlation between brain atrophy, enlargement of the ventricles and cognitive impairment in HIV patients...
  40. ncbi request reprint Intrathecal viral replication and cerebral deficits in different stages of human immunodeficiency virus disease
    Gabriele Arendt
    Department of Neurology, University Hospital of Dusseldorf UKD, Dusseldorf, Germany
    J Neurovirol 13:225-32. 2007
    ..Lumbar puncture should be performed in all positive patients to identify members of this subgroup and to ascertain what characteristic factors they have in common in order to improve therapy...
  41. ncbi request reprint The electrophysiology of cluster headache
    Dagny Holle
    Department of Neurology, University of Duisburg Essen, Hufelandstrasse 55, 45122 Essen, Germany
    Curr Pain Headache Rep 13:155-9. 2009
    ..Cortical and brainstem reflexes are reviewed to illuminate the pathophysiology of CH...
  42. ncbi request reprint Carotid intima-media thickness in HIV-infected individuals: relationship of premature atherosclerosis to neuropsychological deficits?
    Ozgur Yaldizli
    Department of Neurology, University of Duisburg Essen, Germany
    Eur Neurol 55:166-71. 2006
    ..Therefore, the objective of this study was to investigate the correlation between IMT and neuropsychological deficits in HIV patients...
  43. doi request reprint Post-traumatic headache: is it for real? Crossfire debates on headache: pro
    Mark Obermann
    Department of Neurology, University of Duisburg Essen, Essen, Germany
    Headache 50:710-5. 2010
    ..Investigators should refrain from oversimplifying these complex mechanisms as hysteric exaggeration of everyday complains and from implying greed as motivation for this potentially very disabling disease...
  44. pmc Increased activity of serotonin uptake in platelets in medication overuse headache following regular intake of analgesics and triptans
    Ilya Ayzenberg
    Department of Neurology, University of Duisburg Essen, Hufelandstr 55, Essen 45122, Germany
    J Headache Pain 9:109-12. 2008
    ....