H H Niller

Summary

Affiliation: University of Regensburg
Country: Germany

Publications

  1. ncbi request reprint Epstein-Barr Virus: Clinical Diagnostics
    Hans Helmut Niller
    Institute of Medical Microbiology and Hygiene, University of Regensburg, Franz Josef Straus Allee 11, D 93053, Regensburg, Germany
    Methods Mol Biol 1532:33-55. 2017
  2. pmc Similarities between the Epstein-Barr Virus (EBV) Nuclear Protein EBNA1 and the Pioneer Transcription Factor FoxA: Is EBNA1 a "Bookmarking" Oncoprotein that Alters the Host Cell Epigenotype?
    Hans Helmut Niller
    Institute for Medical Microbiology and Hygiene, University of Regensburg, Franz Josef Straus Allee 11, Regensburg D 93053, Germany
    Pathogens 1:37-51. 2012
  3. doi request reprint Patho-epigenetics of Infectious Diseases Caused by Intracellular Bacteria
    Hans Helmut Niller
    Institute of Medical Microbiology and Hygiene, University of Regensburg, Regensburg, Germany
    Adv Exp Med Biol 879:107-30. 2016
  4. doi request reprint Epigenetic Alterations in Epstein-Barr Virus-Associated Diseases
    Hans Helmut Niller
    Institute of Medical Microbiology and Hygiene, University of Regensburg, Regensburg, Germany
    Adv Exp Med Biol 879:39-69. 2016
  5. pmc May early intervention with high dose intravenous immunoglobulin pose a potentially successful treatment for severe cases of tick-borne encephalitis?
    Daniel Ruzek
    Academy of Sciences of the Czech Republic, Biology Centre, Institute of Parasitology, Branisovska 31, CZ 37005 Ceske Budejovice, Czech Republic
    BMC Infect Dis 13:306. 2013
  6. ncbi request reprint Epigenetic dysregulation of epstein-barr virus latency and development of autoimmune disease
    Hans Helmut Niller
    Institute for Medical Microbiology and Hygiene of the University of Regensburg, Regensburg, Germany
    Adv Exp Med Biol 711:82-102. 2011
  7. doi request reprint Myelodysplastic syndrome (MDS) as a late stage of subclinical hemophagocytic lymphohistiocytosis (HLH): a putative role for Leptospira infection. A hypothesis
    H H Niller
    Universitat Regensburg, Institut fur Medizinische Mikrobiologie und Hygiene, Franz Josef Straus Allee 11, 93053 Regensburg, Germany
    Acta Microbiol Immunol Hung 57:181-9. 2010
  8. doi request reprint Viral hit and run-oncogenesis: genetic and epigenetic scenarios
    Hans Helmut Niller
    Institute for Medical Microbiology and Hygiene of the University of Regensburg, Franz Josef Strauss Allee 11, Regensburg, Germany
    Cancer Lett 305:200-17. 2011
  9. doi request reprint Epigenetic dysregulation of the host cell genome in Epstein-Barr virus-associated neoplasia
    Hans Helmut Niller
    Institute for Medical Microbiology and Hygiene at the University of Regensburg, Franz Josef Strauss Allee 11, D 93053 Regensburg, Germany
    Semin Cancer Biol 19:158-64. 2009
  10. ncbi request reprint A 30 kb region of the Epstein-Barr virus genome is colinear with the rearranged human immunoglobulin gene loci: implications for a "ping-pong evolution" model for persisting viruses and their hosts. A review
    H H Niller
    Institute for Medical Microbiology and Hygiene, University of Regensburg, Research Center, Landshuter Str 22, D 93047 Regensburg, Germany
    Acta Microbiol Immunol Hung 51:469-84. 2004

Collaborators

Detail Information

Publications18

  1. ncbi request reprint Epstein-Barr Virus: Clinical Diagnostics
    Hans Helmut Niller
    Institute of Medical Microbiology and Hygiene, University of Regensburg, Franz Josef Straus Allee 11, D 93053, Regensburg, Germany
    Methods Mol Biol 1532:33-55. 2017
    ..For practical procedures, we refer to the detailed instruction manuals of the respective test kit manufacturers which have to be closely followed for reliable results...
  2. pmc Similarities between the Epstein-Barr Virus (EBV) Nuclear Protein EBNA1 and the Pioneer Transcription Factor FoxA: Is EBNA1 a "Bookmarking" Oncoprotein that Alters the Host Cell Epigenotype?
    Hans Helmut Niller
    Institute for Medical Microbiology and Hygiene, University of Regensburg, Franz Josef Straus Allee 11, Regensburg D 93053, Germany
    Pathogens 1:37-51. 2012
    ..We suggest that EBNA1 has the potential to induce patho-epigenetic alterations contributing to tumorigenesis. ..
  3. doi request reprint Patho-epigenetics of Infectious Diseases Caused by Intracellular Bacteria
    Hans Helmut Niller
    Institute of Medical Microbiology and Hygiene, University of Regensburg, Regensburg, Germany
    Adv Exp Med Biol 879:107-30. 2016
    ..Such indirect epigenetic changes as well as direct interference with the epigenetic machinery of the host cells may contribute to the initiation and progression of malignant tumors associated with distinct bacterial infections. ..
  4. doi request reprint Epigenetic Alterations in Epstein-Barr Virus-Associated Diseases
    Hans Helmut Niller
    Institute of Medical Microbiology and Hygiene, University of Regensburg, Regensburg, Germany
    Adv Exp Med Biol 879:39-69. 2016
    ....
  5. pmc May early intervention with high dose intravenous immunoglobulin pose a potentially successful treatment for severe cases of tick-borne encephalitis?
    Daniel Ruzek
    Academy of Sciences of the Czech Republic, Biology Centre, Institute of Parasitology, Branisovska 31, CZ 37005 Ceske Budejovice, Czech Republic
    BMC Infect Dis 13:306. 2013
    ..Regardless of these shortcomings, there are an increasing number of case reports that successfully treat arboviral encephalitis with high doses of intravenous immunoglobulins...
  6. ncbi request reprint Epigenetic dysregulation of epstein-barr virus latency and development of autoimmune disease
    Hans Helmut Niller
    Institute for Medical Microbiology and Hygiene of the University of Regensburg, Regensburg, Germany
    Adv Exp Med Biol 711:82-102. 2011
    ....
  7. doi request reprint Myelodysplastic syndrome (MDS) as a late stage of subclinical hemophagocytic lymphohistiocytosis (HLH): a putative role for Leptospira infection. A hypothesis
    H H Niller
    Universitat Regensburg, Institut fur Medizinische Mikrobiologie und Hygiene, Franz Josef Straus Allee 11, 93053 Regensburg, Germany
    Acta Microbiol Immunol Hung 57:181-9. 2010
    ..Infections by agents other than Leptospira may lead to subclinical HLH-like disease with MDS as a late stage as well...
  8. doi request reprint Viral hit and run-oncogenesis: genetic and epigenetic scenarios
    Hans Helmut Niller
    Institute for Medical Microbiology and Hygiene of the University of Regensburg, Franz Josef Strauss Allee 11, Regensburg, Germany
    Cancer Lett 305:200-17. 2011
    ..e. alterations of the host cell epigenome, especially altered DNA methylation patterns, may help to identify viral hit and run-oncogenic events, even after the complete loss of tumor viruses from neoplastic cells...
  9. doi request reprint Epigenetic dysregulation of the host cell genome in Epstein-Barr virus-associated neoplasia
    Hans Helmut Niller
    Institute for Medical Microbiology and Hygiene at the University of Regensburg, Franz Josef Strauss Allee 11, D 93053 Regensburg, Germany
    Semin Cancer Biol 19:158-64. 2009
    ..Analysis of epigenetic alterations in EBV-associated neoplasms may result in a better understanding of their pathogenesis and may facilitate the development of new therapies...
  10. ncbi request reprint A 30 kb region of the Epstein-Barr virus genome is colinear with the rearranged human immunoglobulin gene loci: implications for a "ping-pong evolution" model for persisting viruses and their hosts. A review
    H H Niller
    Institute for Medical Microbiology and Hygiene, University of Regensburg, Research Center, Landshuter Str 22, D 93047 Regensburg, Germany
    Acta Microbiol Immunol Hung 51:469-84. 2004
    ..We suggest that persisting viruses served as a complement for the organismal germline like in a ping-pong game and outline The Ping-Pong Evolution Hypothesis...
  11. ncbi request reprint The LCR of EBV makes Burkitt's lymphoma endemic
    Hans H Niller
    Institute for Medical Microbiology and Hygiene, University of Regensburg, Research Center, Landshuter Strasse 22, D 93047 Regensburg, Germany
    Trends Microbiol 12:495-9. 2004
    ....
  12. ncbi request reprint The in vivo binding site for oncoprotein c-Myc in the promoter for Epstein-Barr virus (EBV) encoding RNA (EBER) 1 suggests a specific role for EBV in lymphomagenesis
    Hans H Niller
    Institute for Medical Microbiology and Hygiene, University of Regensburg, Research Center, Regensburg, Germany
    Med Sci Monit 9:HY1-9. 2003
    ....
  13. pmc Nucleoprotein structure of immediate-early promoters Zp and Rp and of oriLyt of latent Epstein-Barr virus genomes
    Hans Helmut Niller
    Institut fur Medizinische Mikrobiologie und Hygiene, Universitat Regensburg, D 93053 Regensburg, Germany
    J Virol 76:4113-8. 2002
    ..Gel shifts and transient transfection assays indicated that an Sp1-NF1 locus may serve as a repressive transcriptional element against Zp induction from latent EBV genomes...
  14. pmc In vitro activities of six quinolones and mechanisms of resistance in Staphylococcus aureus and coagulase-negative staphylococci
    H J Linde
    Institute for Medical Microbiology and Hygiene, University of Regensburg, Regensburg, Germany
    Antimicrob Agents Chemother 45:1553-7. 2001
    ..Among ciprofloxacin, clinafloxacin, levofloxacin, nalidixic acid, trovafloxacin, and sparfloxacin, a 0.5-microg/ml concentration of sparfloxacin discriminated best between strains with two or three mutations and those with no mutations...
  15. ncbi request reprint Protein-DNA interaction and CpG methylation at rep*/vIL-10p of latent Epstein-Barr virus genomes in lymphoid cell lines
    H H Niller
    , , Germany
    Biol Chem 382:1411-9. 2001
    ..This result is in agreement with vIL-10p being an inactive promoter of EBV genomes, and makes it less likely that rep* functions as a replicative element of latent EBV genomes...
  16. ncbi request reprint Specific nucleoprotein complexes within adenovirus capsids
    T Dobner
    , , Germany
    Biol Chem 382:1373-7. 2001
    ..There were no indications of close protein binding at several other loci of the viral genome. Therefore, adenovirus type 5 seems to contain sequence- or locus-specific DNA binding proteins within the virion...
  17. ncbi request reprint Epigenetics of latent Epstein-Barr virus genomes: high resolution methylation analysis of the bidirectional promoter region of latent membrane protein 1 and 2B genes
    M Takacs
    Division of Virology, National Center for Epidemiology, Budapest, Hungary
    Biol Chem 382:699-705. 2001
    ....
  18. pmc Protein-DNA binding and CpG methylation at nucleotide resolution of latency-associated promoters Qp, Cp, and LMP1p of Epstein-Barr virus
    D Salamon
    Microbiological Research Group, National Center for Epidemiology, H-1529 Budapest, Hungary
    J Virol 75:2584-96. 2001
    ..Novel protein binding data were obtained for all promoters. For Cp, binding correlated well with promoter activity; for LMP1p and Qp, binding patterns looked similar regardless of promoter activity...