H H Niller
Affiliation: University of Regensburg
Niller H, Minarovits J. Similarities between the Epstein-Barr Virus (EBV) Nuclear Protein EBNA1 and the Pioneer Transcription Factor FoxA: Is EBNA1 a "Bookmarking" Oncoprotein that Alters the Host Cell Epigenotype?. Pathogens. 2012;1:37-51 pubmed publisher
..We suggest that EBNA1 has the potential to induce patho-epigenetic alterations contributing to tumorigenesis. ..
Minarovits J, DemcsÃ¡k A, Banati F, Niller H. Epigenetic Dysregulation in Virus-Associated Neoplasms. Adv Exp Med Biol. 2016;879:71-90 pubmed publisher
..Tax and HBZ, the oncoproteins of human T-cell lymphotropic virus type I (HTLV-I), can both activate and silence distinct cellular promoters by interacting with cellular enzymes involved in histone modification. ..
Niller H. Myelodysplastic syndrome (MDS) as a late stage of subclinical hemophagocytic lymphohistiocytosis (HLH): a putative role for Leptospira infection. A hypothesis. Acta Microbiol Immunol Hung. 2010;57:181-9 pubmed publisher
..Infections by agents other than Leptospira may lead to subclinical HLH-like disease with MDS as a late stage as well. ..
Niller H, Bauer G. Epstein-Barr Virus: Clinical Diagnostics. Methods Mol Biol. 2017;1532:33-55 pubmed
..For practical procedures, we refer to the detailed instruction manuals of the respective test kit manufacturers which have to be closely followed for reliable results. ..
Niller H, Wolf H, Minarovits J. Epigenetic dysregulation of the host cell genome in Epstein-Barr virus-associated neoplasia. Semin Cancer Biol. 2009;19:158-64 pubmed publisher
..Analysis of epigenetic alterations in EBV-associated neoplasms may result in a better understanding of their pathogenesis and may facilitate the development of new therapies...
Niller H, Wolf H, Minarovits J. Viral hit and run-oncogenesis: genetic and epigenetic scenarios. Cancer Lett. 2011;305:200-17 pubmed publisher
..e. alterations of the host cell epigenome, especially altered DNA methylation patterns, may help to identify viral hit and run-oncogenic events, even after the complete loss of tumor viruses from neoplastic cells...