Research Topics
Species | Charlotte Marie NiemeyerSummaryAffiliation: University Hospital Country: Germany Publications
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Detail Information
Publications
Germline CBL mutations cause developmental abnormalities and predispose to juvenile myelomonocytic leukemiaCharlotte M Niemeyer
Department of Pediatrics and Adolescent Medicine, University of Freiburg, Freiburg, Germany
Nat Genet 42:794-800. 2010....
Paediatric myelodysplastic syndromes and juvenile myelomonocytic leukaemia: molecular classification and treatment optionsCharlotte Marie Niemeyer
Department of Paediatrics and Adolescent Medicine, University of Freiburg, Freiburg, Germany
Br J Haematol 140:610-24. 2008..Research on genetic conditions predisposing to MDS in young age, such as inherited syndromes with bone marrow failure, may present important insights into MDS pathogenesis...
Myelodysplastic syndrome in children and adolescentsCharlotte M Niemeyer
Division of Pediatric Hematology and Oncology, Department of Pediatrics, University of Freiburg, Freiburg, Germany
Semin Hematol 45:60-70. 2008..Allogeneic hematopoietic stem cell transplantation (HSCT) from a matched related or suitable unrelated donor is the choice for most children with MDS and can rescue a large proportion of patients...
EGFR inhibition using gefitinib is not active in neuroblastoma cell linesJochen Rossler
Department of Pediatrics and Adolescent Medicine, University Hospital of Freiburg, 79106 Freiburg, Germany
Anticancer Res 29:1327-33. 2009..Inhibition of the epidermal growth factor receptor (EGFR), using a tyrosine kinase inhibitor such as gefitinib, was suggested to be a new treatment approach for neuroblastoma...
Pediatric myelodysplastic syndromesCharlotte Marie Niemeyer
Division of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, University of Freiburg, Mathildenstrasse 1, 79106 Freiburg, Germany
Curr Treat Options Oncol 6:209-14. 2005..Unraveling some of the underlying genetic factors predisposing to MDS at a young age may give important insights into leukemogenesis in the elderly...
Lymphangiogenesis and its regulation in human neuroblastomaJeanette Lagodny
Division of Pediatric Hematology Oncology, Department of Pediatrics and Adolescent Medicine, Mathilsdenstr 1, 79106 Freiburg, Germany
Biochem Biophys Res Commun 352:571-7. 2007..We conclude that lymphangiogenesis is involved in NB biology and that siRNA directed against VEGF-C may have a future role in anti-lymphangiogenic strategies in NB...
Alveolar rhabdomyosarcoma mimicking lymphoma with bone marrow involvementChristof Andreas Hanke
Department of Pediatrics and Adolescent Medicine, Division of Pediatric Hematology and Oncology, University of Freiburg, Mathildenstrasse 1, 79106, Freiburg, Germany
Eur J Pediatr 166:505-6. 2007
Lethal proliferation of erythroid precursors in a neonate with a germline PTPN11 mutationChristian Peter Kratz
Department of Pediatrics and Adolescent Medicine, University of Freiburg, Freiburg, Germany
Eur J Pediatr 165:182-5. 2006..In conclusion, this case report suggests that congenital myeloproliferative disorders in association with germline PTPN11 mutations may affect the erythroid lineage...
Myelodysplastic features in an infant with cystic fibrosis presenting with anaemia, oedema and failure to thriveChristian Peter Kratz
Department of Paediatrics and Adolescent Medicine, University of Freiburg, Freiburg, Germany
Eur J Pediatr 164:56-7. 2005
Effect of STI-571 (imatinib mesylate) in combination with retinoic acid and gamma-irradiation on viability of neuroblastoma cellsJochen Rossler
Division of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, University Hospital of Freiburg, Germany
Biochem Biophys Res Commun 342:1405-12. 2006..Treatment of NB with STI-571 in combination with 9-cis RA might be a therapeutic strategy for patients in consolidation therapy who have completed gamma-irradiation therapy...
Evaluating systemic prednisone therapy for proliferating haemangioma in infancyJochen Rossler
Department of Pediatrics and Adolescent Medicine, Division of Pediatric Hematology and Oncology, University of Freiburg, Freiburg, Germany
Eur J Pediatr 167:813-5. 2008..For 93% of the children, this protocol was successful in reducing the size of the haemangioma by more than 25% after 2 weeks of treatment. Side effects were moderate and reversible after cessation of therapy...
Hematologic features and clinical course of an infant with Pearson syndrome caused by a novel deletion of mitochondrial DNAIna Knerr
Department of Pediatrics, University of Erlangen Nuremberg, Germany
J Pediatr Hematol Oncol 25:948-51. 2003..371 to 14.607...
Juvenile myelomonocytic leukemiaCharlotte Marie Niemeyer
Division of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, University of Freiburg, Mathildenstrasse 1, 79106 Freiburg, Germany
Curr Treat Options Oncol 4:203-10. 2003....
