P Neudecker

Summary

Affiliation: University of Bayreuth
Country: Germany

Publications

  1. ncbi Mutational epitope analysis of Pru av 1 and Api g 1, the major allergens of cherry (Prunus avium) and celery (Apium graveolens): correlating IgE reactivity with three-dimensional structure
    Philipp Neudecker
    Lehrstuhl für Biopolymere, Universitaet Bayreuth, Universitatsstrasse 30, 95440 Bayreuth, Germany
    Biochem J 376:97-107. 2003
  2. ncbi Solution structure, dynamics, and hydrodynamics of the calcium-bound cross-reactive birch pollen allergen Bet v 4 reveal a canonical monomeric two EF-hand assembly with a regulatory function
    Philipp Neudecker
    Lehrstuhl für Biopolymere, Universitat Bayreuth, D 95440 Bayreuth, Germany
    J Mol Biol 336:1141-57. 2004
  3. ncbi Solution structure of human proguanylin: the role of a hormone prosequence
    Thomas Lauber
    Lehrstuhl für Biopolymere, Universitat Bayreuth, Universitatstrasse 30, 95447 Bayreuth, Germany
    J Biol Chem 278:24118-24. 2003
  4. ncbi A novel approach for investigation of specific and cross-reactive IgE epitopes on Bet v 1 and homologous food allergens in individual patients
    Diana Mittag
    Allergy Unit, Department of Dermatology, University Hospital Zurich, Switzerland
    Mol Immunol 43:268-78. 2006
  5. ncbi Sequence-specific 1H, 13C and 15N resonance assignments of Ara h 6, an allergenic 2S albumin from peanut
    Katrin Lehmann
    J Biomol NMR 29:93-4. 2004
  6. ncbi High-yield expression in Escherichia coli, purification, and characterization of properly folded major peanut allergen Ara h 2
    Katrin Lehmann
    Lehrstuhl Biopolymere, , Universitaetsstrasse 30, 95440, Bayreuth, Germany
    Protein Expr Purif 31:250-9. 2003
  7. ncbi Sequence-specific 1H, 13C and 15N resonance assignments of SAM22, an allergenic stress-induced protein from soy bean
    Philipp Neudecker
    J Biomol NMR 26:191-2. 2003
  8. ncbi Assessment of the effects of increased relaxation dispersion data on the extraction of 3-site exchange parameters characterizing the unfolding of an SH3 domain
    Philipp Neudecker
    Department of Medical Genetics, University of Toronto, ON, Canada
    J Biomol NMR 34:129-35. 2006
  9. ncbi Abp1p and Fyn SH3 domains fold through similar low-populated intermediate states
    Dmitry M Korzhnev
    Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada, M5S 1A8
    Biochemistry 45:10175-83. 2006
  10. ncbi Identification of a collapsed intermediate with non-native long-range interactions on the folding pathway of a pair of Fyn SH3 domain mutants by NMR relaxation dispersion spectroscopy
    Philipp Neudecker
    Departments of Medical Genetics and Biochemistry, University of Toronto, Toronto, ON, Canada M5S 1A8
    J Mol Biol 363:958-76. 2006

Collaborators

  • Fatima Ferreira
  • Lewis E Kay
  • Barbara K Ballmer-Weber
  • S Schwarzinger
  • Katrin Lehmann
  • Arash Zarrine-Afsar
  • D Flemming Hansen
  • Alan R Davidson
  • Dmitry M Korzhnev
  • Diana Mittag
  • Thomas Lauber
  • Stefan Wallin
  • Hue Sun Chan
  • A Mirela Neculai
  • P Lynne Howell
  • Pramodh Vallurupalli
  • Patrik Lundström
  • Erwin L Roggen
  • Esben P Friis
  • Stefan Vieths
  • Vincent Batori
  • Regina Wiche
  • Kristian Schweimer
  • Ute C Marx
  • Paul Rosch
  • Silke Hoffmann
  • Martin Suhr
  • Wolf-Meinhard Becker

Detail Information

Publications13

  1. ncbi Mutational epitope analysis of Pru av 1 and Api g 1, the major allergens of cherry (Prunus avium) and celery (Apium graveolens): correlating IgE reactivity with three-dimensional structure
    Philipp Neudecker
    Lehrstuhl für Biopolymere, Universitaet Bayreuth, Universitatsstrasse 30, 95440 Bayreuth, Germany
    Biochem J 376:97-107. 2003
    ....
  2. ncbi Solution structure, dynamics, and hydrodynamics of the calcium-bound cross-reactive birch pollen allergen Bet v 4 reveal a canonical monomeric two EF-hand assembly with a regulatory function
    Philipp Neudecker
    Lehrstuhl für Biopolymere, Universitat Bayreuth, D 95440 Bayreuth, Germany
    J Mol Biol 336:1141-57. 2004
    ..Together with the close structural homology to calmodulin and the hydrophobic ligand binding groove this transition suggests a regulatory function for Bet v 4...
  3. ncbi Solution structure of human proguanylin: the role of a hormone prosequence
    Thomas Lauber
    Lehrstuhl für Biopolymere, Universitat Bayreuth, Universitatstrasse 30, 95447 Bayreuth, Germany
    J Biol Chem 278:24118-24. 2003
    ....
  4. ncbi A novel approach for investigation of specific and cross-reactive IgE epitopes on Bet v 1 and homologous food allergens in individual patients
    Diana Mittag
    Allergy Unit, Department of Dermatology, University Hospital Zurich, Switzerland
    Mol Immunol 43:268-78. 2006
    ..Such basic information on epitope structure may be used for prediction of cross-reactivity and potential allergenicity of novel foods...
  5. ncbi Sequence-specific 1H, 13C and 15N resonance assignments of Ara h 6, an allergenic 2S albumin from peanut
    Katrin Lehmann
    J Biomol NMR 29:93-4. 2004
  6. ncbi High-yield expression in Escherichia coli, purification, and characterization of properly folded major peanut allergen Ara h 2
    Katrin Lehmann
    Lehrstuhl Biopolymere, , Universitaetsstrasse 30, 95440, Bayreuth, Germany
    Protein Expr Purif 31:250-9. 2003
    ..It could be shown that recombinant Ara h 2, thus overexpressed and purified, and the allergen isolated from peanuts are identical as judged from immunoblotting, analytical HPLC, and circular dichroism spectra...
  7. ncbi Sequence-specific 1H, 13C and 15N resonance assignments of SAM22, an allergenic stress-induced protein from soy bean
    Philipp Neudecker
    J Biomol NMR 26:191-2. 2003
  8. ncbi Assessment of the effects of increased relaxation dispersion data on the extraction of 3-site exchange parameters characterizing the unfolding of an SH3 domain
    Philipp Neudecker
    Department of Medical Genetics, University of Toronto, ON, Canada
    J Biomol NMR 34:129-35. 2006
    ....
  9. ncbi Abp1p and Fyn SH3 domains fold through similar low-populated intermediate states
    Dmitry M Korzhnev
    Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada, M5S 1A8
    Biochemistry 45:10175-83. 2006
    ....
  10. ncbi Identification of a collapsed intermediate with non-native long-range interactions on the folding pathway of a pair of Fyn SH3 domain mutants by NMR relaxation dispersion spectroscopy
    Philipp Neudecker
    Departments of Medical Genetics and Biochemistry, University of Toronto, Toronto, ON, Canada M5S 1A8
    J Mol Biol 363:958-76. 2006
    ....
  11. ncbi Phi-value analysis of a three-state protein folding pathway by NMR relaxation dispersion spectroscopy
    Philipp Neudecker
    Department of Medical Genetics, University of Toronto, Toronto, ON, Canada M5S 1A8
    Proc Natl Acad Sci U S A 104:15717-22. 2007
    ..The results further support the notion that on-pathway intermediates can be stabilized by nonnative contacts...
  12. ncbi Probing chemical shifts of invisible states of proteins with relaxation dispersion NMR spectroscopy: how well can we do?
    D Flemming Hansen
    Department of Medical Genetics, University of Toronto, Toronto, Ontario, Canada, M5S 1A8
    J Am Chem Soc 130:2667-75. 2008
    ..The accuracy of the extracted chemical shifts opens up the possibility of obtaining quantitative structural information of invisible states of the sort that is now available from chemical shifts recorded on ground states of proteins...
  13. ncbi Theoretical and experimental demonstration of the importance of specific nonnative interactions in protein folding
    Arash Zarrine-Afsar
    Department of Biochemistry, University of Toronto, Toronto, ON, Canada
    Proc Natl Acad Sci U S A 105:9999-10004. 2008
    ..Moreover, we show that a coarse-grained model with a simple consideration of hydrophobicity is sufficient for the accurate prediction of kinetically important nonnative interactions...