Bjorn Nashan

Summary

Affiliation: University Medical Center Hamburg-Eppendorf
Country: Germany

Publications

  1. doi request reprint Induction therapy and mTOR inhibition: minimizing calcineurin inhibitor exposure in de novo renal transplant patients
    Bjorn Nashan
    Department of Hepatobiliary Surgery and Visceral Transplantation, University Medical Center Eppendorf, Hamburg, Germany
    Clin Transplant 27:16-29. 2013
  2. pmc Combined targeting of AKT and mTOR synergistically inhibits proliferation of hepatocellular carcinoma cells
    Nicole Grabinski
    Center for Experimental Medicine, Institute of Biochemistry and Signal Transduction, University Medical Center Hamburg Eppendorf, Martinistr 52, Hamburg 20246, Germany
    Mol Cancer 11:85. 2012
  3. ncbi request reprint Wound healing complications and the use of mammalian target of rapamycin inhibitors in kidney transplantation: a critical review of the literature
    Bjorn Nashan
    Department of Hepatobiliary Surgery and Visceral Transplantation, University Medical Center Eppendorf, Hamburg, Germany
    Transplantation 94:547-61. 2012
  4. ncbi request reprint Donor quality of life up to two years after living donor liver transplantation: a prospective study
    Sylvia Kroencke
    1 Department of Medical Psychology, University Medical Center Hamburg Eppendorf, Hamburg, Germany 2 Department of Hepatobiliary and Transplant Surgery, University Medical Center Hamburg Eppendorf, Hamburg, Germany 3 Department of Psychosomatics and Psychotherapy, Erlangen University Hospital, Erlangen, Germany 4 Address correspondence to Prof Karl Heinz Schulz, M D, Ph D, Department of Medical Psychology, University Medical Center Hamburg Eppendorf, Martinistr 52, W26, 20246 Hamburg, Germany
    Transplantation 97:582-9. 2014
  5. doi request reprint Immediate postoperative intensive care treatment of pediatric combined liver-kidney transplantation: outcome and prognostic factors
    Egmont Harps
    Department of Pediatrics, Pediatric Intensive Care Unit, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Transplantation 91:1127-31. 2011
  6. doi request reprint Review of cytomegalovirus infection findings with mammalian target of rapamycin inhibitor-based immunosuppressive therapy in de novo renal transplant recipients
    Bjorn Nashan
    Department of Hepatobiliary Surgery and Visceral Transplantation, University Hospital Hamburg Eppendorf, Hamburg, Germany
    Transplantation 93:1075-85. 2012
  7. doi request reprint Four-year allograft survival in a highly sensitized combined liver-kidney transplant patient despite unsuccessful anti-HLA antibody reduction with rituximab, splenectomy, and bortezomib
    Martina Koch
    Department of Hepatobiliary and Transplant Surgery, University Medical Center Hamburg Eppendorf, UKE, Hamburg, Germany
    Transpl Int 26:e64-8. 2013
  8. doi request reprint Cost-effectiveness analysis of antiviral treatment in liver transplant recipients with HCV infection
    Christoph Logge
    Department of Hepatobiliary Surgery and Visceral Transplantation, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Transpl Int 26:527-34. 2013
  9. doi request reprint A prospective study on living related kidney donors' quality of life in the first year: choosing appropriate reference data
    Sylvia Kroencke
    Department of Hepatobiliary and Transplant Surgery, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Clin Transplant 26:E418-27. 2012
  10. doi request reprint Presence of EpCAM-positive circulating tumor cells as biomarker for systemic disease strongly correlates to survival in patients with hepatocellular carcinoma
    Kornelius Schulze
    I Department of Medicine, Gastroenterology and Hepatology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Int J Cancer 133:2165-71. 2013

Collaborators

Detail Information

Publications13

  1. doi request reprint Induction therapy and mTOR inhibition: minimizing calcineurin inhibitor exposure in de novo renal transplant patients
    Bjorn Nashan
    Department of Hepatobiliary Surgery and Visceral Transplantation, University Medical Center Eppendorf, Hamburg, Germany
    Clin Transplant 27:16-29. 2013
    ....
  2. pmc Combined targeting of AKT and mTOR synergistically inhibits proliferation of hepatocellular carcinoma cells
    Nicole Grabinski
    Center for Experimental Medicine, Institute of Biochemistry and Signal Transduction, University Medical Center Hamburg Eppendorf, Martinistr 52, Hamburg 20246, Germany
    Mol Cancer 11:85. 2012
    ..In addition, we measured the feedback activation of each of the AKT isoforms after mTOR inhibition in HCC cell lines and their enzymatic activity in primary samples from HCC patients...
  3. ncbi request reprint Wound healing complications and the use of mammalian target of rapamycin inhibitors in kidney transplantation: a critical review of the literature
    Bjorn Nashan
    Department of Hepatobiliary Surgery and Visceral Transplantation, University Medical Center Eppendorf, Hamburg, Germany
    Transplantation 94:547-61. 2012
    ..This review summarizes these studies to consider whether modern mTOR inhibitor-based immunosuppressive regimens exert and affect wound healing after kidney transplantation...
  4. ncbi request reprint Donor quality of life up to two years after living donor liver transplantation: a prospective study
    Sylvia Kroencke
    1 Department of Medical Psychology, University Medical Center Hamburg Eppendorf, Hamburg, Germany 2 Department of Hepatobiliary and Transplant Surgery, University Medical Center Hamburg Eppendorf, Hamburg, Germany 3 Department of Psychosomatics and Psychotherapy, Erlangen University Hospital, Erlangen, Germany 4 Address correspondence to Prof Karl Heinz Schulz, M D, Ph D, Department of Medical Psychology, University Medical Center Hamburg Eppendorf, Martinistr 52, W26, 20246 Hamburg, Germany
    Transplantation 97:582-9. 2014
    ..There is a lack of longer-term prospective data on living liver donors' quality of life (QOL). This is the first prospective study examining QOL up to 2 years after donation...
  5. doi request reprint Immediate postoperative intensive care treatment of pediatric combined liver-kidney transplantation: outcome and prognostic factors
    Egmont Harps
    Department of Pediatrics, Pediatric Intensive Care Unit, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Transplantation 91:1127-31. 2011
    ..Studies reporting the immediate pediatric intensive care unit (PICU) treatment after combined liver-kidney transplantation (CLKT) are scarce, although this period is pivotal for survival and long-term outcome...
  6. doi request reprint Review of cytomegalovirus infection findings with mammalian target of rapamycin inhibitor-based immunosuppressive therapy in de novo renal transplant recipients
    Bjorn Nashan
    Department of Hepatobiliary Surgery and Visceral Transplantation, University Hospital Hamburg Eppendorf, Hamburg, Germany
    Transplantation 93:1075-85. 2012
    ..This review will summarize these studies to discuss whether mTOR inhibitor-based immunosuppressive therapy can reduce the magnitude of CMV-related complications in the de novo renal transplantation setting...
  7. doi request reprint Four-year allograft survival in a highly sensitized combined liver-kidney transplant patient despite unsuccessful anti-HLA antibody reduction with rituximab, splenectomy, and bortezomib
    Martina Koch
    Department of Hepatobiliary and Transplant Surgery, University Medical Center Hamburg Eppendorf, UKE, Hamburg, Germany
    Transpl Int 26:e64-8. 2013
    ..So far, patient and allograft survival has reached 4 years despite failure to achieve a permanent reduction of anti-HLA antibodies, and particularly nondonor directed antibodies...
  8. doi request reprint Cost-effectiveness analysis of antiviral treatment in liver transplant recipients with HCV infection
    Christoph Logge
    Department of Hepatobiliary Surgery and Visceral Transplantation, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Transpl Int 26:527-34. 2013
    ..We conclude that Peg-IFN/RBV treatment is cost-effective post transplant. This may support treatment decision in individual cases...
  9. doi request reprint A prospective study on living related kidney donors' quality of life in the first year: choosing appropriate reference data
    Sylvia Kroencke
    Department of Hepatobiliary and Transplant Surgery, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Clin Transplant 26:E418-27. 2012
    ..Future research needs to determine the length and the nature of the post-operative QoL impairment and further explore possible influencing factors...
  10. doi request reprint Presence of EpCAM-positive circulating tumor cells as biomarker for systemic disease strongly correlates to survival in patients with hepatocellular carcinoma
    Kornelius Schulze
    I Department of Medicine, Gastroenterology and Hepatology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Int J Cancer 133:2165-71. 2013
    ..050). Our study demonstrates frequent presence of EpCAM-positive CTC in patients with intermediate or advanced HCC and its prognostic value for OS with possible implications for future treatment stratification. ..
  11. doi request reprint Monitoring of nuclear factor of activated T-cell-regulated gene expression in de novo and long-term liver transplant recipients treated with cyclosporine a
    Uta Herden
    Department of Hepatobiliary Surgery and Solid Organ Transplantation, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Ther Drug Monit 33:185-91. 2011
    ..The data suggest that CsA C2 concentrations, but not C0 concentrations, reflect the effect of CsA on downregulation of cytokine expression in both de novo and long-term liver transplant patients...
  12. doi request reprint Combined targeting of AKT and mTOR using MK-2206 and RAD001 is synergistic in the treatment of cholangiocarcinoma
    Florian Ewald
    Department of Hepatobiliary and Transplant Surgery, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Int J Cancer 133:2065-76. 2013
    ..In summary, our preclinical data suggest that combined targeting of mTOR and AKT using RAD001 and MK-2206 might be a new, effective strategy for the treatment of CCA. ..
  13. ncbi request reprint Attention and executive functioning deficits in liver-transplanted children
    Tanja Kaller
    Institute of Medical Psychology, University Hospital Eppendorf, Hamburg, Germany
    Transplantation 90:1567-73. 2010
    ..Liver-transplanted children have an increased risk for serious developmental problems. We examined attention and executive functioning and their relation to intelligence and several disease-related variables after transplantation...