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..32. This rare tumor shows a similar genetic aberration with other studied thymic epithelial tumors. ..
Nagel I, Akasaka T, Klapper W, Gesk S, Böttcher S, Ritgen M, et al. Identification of the gene encoding cyclin E1 (CCNE1) as a novel IGH translocation partner in t(14;19)(q32;q12) in diffuse large B-cell lymphoma. Haematologica. 2009;94:1020-3 pubmed publisher
..These data indicate that cyclin E1 may act as a novel oncogene in B-cell lymphomagenesis. ..
Nagel I, Szczepanowski M, Martin Subero J, Harder L, Akasaka T, Ammerpohl O, et al. Deregulation of the telomerase reverse transcriptase (TERT) gene by chromosomal translocations in B-cell malignancies. Blood. 2010;116:1317-20 pubmed publisher
..These data suggest that deregulation of TERT gene by chromosomal abnormalities leading to increased telomerase activity might contribute to B-cell lymphomagenesis. ..