Dieter Naber

Summary

Affiliation: University of Hamburg
Country: Germany

Publications

  1. ncbi The relationship, structure and profiles of schizophrenia measurements: a post-hoc analysis of the baseline measures from a randomized clinical trial
    Lei Chen
    Lilly and Company, Lilly Corporate Center, Indianapolis, IN 46285, USA
    BMC Psychiatry 11:203. 2011
  2. ncbi Anticonvulsants in the treatment of aggression in the demented elderly: an update
    Benedikt Amann
    Benito Menni, CASM, Research Unit, CIBERSAM, St Boi de Llobregat, Barcelona, Spain
    Clin Pract Epidemiol Ment Health 5:14. 2009
  3. ncbi Improvement of schizophrenic patients' subjective well-being under atypical antipsychotic drugs
    D Naber
    Universitäts Krankenhaus Hamburg Eppendorf, Clinic for Psychiatry and Psychotherapy, Martinistrasse 52, 20246 Hamburg, Germany
    Schizophr Res 50:79-88. 2001
  4. ncbi The CATIE and CUtLASS studies in schizophrenia: results and implications for clinicians
    Dieter Naber
    Department of Psychiatry and Psychotherapy, Centre for Psychosocial Medicine, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    CNS Drugs 23:649-59. 2009
  5. ncbi Randomized double blind comparison of olanzapine vs. clozapine on subjective well-being and clinical outcome in patients with schizophrenia
    D Naber
    Department of Psychiatry and Psychotherapy, University Hospital Hamburg Eppendorf, Germany
    Acta Psychiatr Scand 111:106-15. 2005
  6. ncbi [Pro and contra: basic precedence of atypical neuroleptics]
    Dieter Naber
    ,
    Psychiatr Prax 32:163-6. 2005
  7. ncbi Olanzapine pamoate for the treatment of schizophrenia
    Dieter Naber
    Klinik fur Psychiatrie und Psychotherapie, Universitatsklinikum Hamburg Eppendorf, Martinistrasse 52, Hamburg, Germany
    Expert Opin Pharmacother 12:627-33. 2011
  8. ncbi Long-term phase of schizophrenia: impact of atypical agents
    D Naber
    Universitat Hamburg, Germany
    Int Clin Psychopharmacol 15:S11-4. 2000
  9. ncbi Aripiprazole: a new atypical antipsychotic with a different pharmacological mechanism
    Dieter Naber
    Department of Psychiatry and Psychotherapy, Universitatsklinikum Hamburg Eppendorf, Martinistrasse 52, Hamburg 20246, Germany
    Prog Neuropsychopharmacol Biol Psychiatry 28:1213-9. 2004
  10. ncbi [Subjective well-being under antipsychotic treatment and its meaning for compliance and course of disease]
    Dieter Naber
    Universitatsklinikum Hamburg Eppendorf, Klinik fur Psychiatrie und Psychotherapie
    Psychiatr Prax 31:S230-2. 2004

Detail Information

Publications120 found, 100 shown here

  1. ncbi The relationship, structure and profiles of schizophrenia measurements: a post-hoc analysis of the baseline measures from a randomized clinical trial
    Lei Chen
    Lilly and Company, Lilly Corporate Center, Indianapolis, IN 46285, USA
    BMC Psychiatry 11:203. 2011
    ..In this exploratory study, we characterized the relationships among six clinical, functional, cognitive, and quality-of-life measures, identifying a parsimonious set of measurements...
  2. ncbi Anticonvulsants in the treatment of aggression in the demented elderly: an update
    Benedikt Amann
    Benito Menni, CASM, Research Unit, CIBERSAM, St Boi de Llobregat, Barcelona, Spain
    Clin Pract Epidemiol Ment Health 5:14. 2009
    ..At least 50% of the dramatically growing number of patients with dementia exerts aggressive and agitated symptoms during the course of clinical progression, particularly at moderate clinical severity...
  3. ncbi Improvement of schizophrenic patients' subjective well-being under atypical antipsychotic drugs
    D Naber
    Universitäts Krankenhaus Hamburg Eppendorf, Clinic for Psychiatry and Psychotherapy, Martinistrasse 52, 20246 Hamburg, Germany
    Schizophr Res 50:79-88. 2001
    ..It is concluded that the assessment of subjective well-being under antipsychotic treatment provides an independent outcome measure which is relevant to compliance...
  4. ncbi The CATIE and CUtLASS studies in schizophrenia: results and implications for clinicians
    Dieter Naber
    Department of Psychiatry and Psychotherapy, Centre for Psychosocial Medicine, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    CNS Drugs 23:649-59. 2009
    ..There is no single antipsychotic that is best for every schizophrenia patient, as individual responses differ markedly. For successfully individualized treatment, a multitude of antipsychotic options are needed...
  5. ncbi Randomized double blind comparison of olanzapine vs. clozapine on subjective well-being and clinical outcome in patients with schizophrenia
    D Naber
    Department of Psychiatry and Psychotherapy, University Hospital Hamburg Eppendorf, Germany
    Acta Psychiatr Scand 111:106-15. 2005
    ..This randomized double-blind multicenter trial evaluated the effects of olanzapine vs. clozapine on subjective well-being, quality of life (QOL) and clinical outcome...
  6. ncbi [Pro and contra: basic precedence of atypical neuroleptics]
    Dieter Naber
    ,
    Psychiatr Prax 32:163-6. 2005
  7. ncbi Olanzapine pamoate for the treatment of schizophrenia
    Dieter Naber
    Klinik fur Psychiatrie und Psychotherapie, Universitatsklinikum Hamburg Eppendorf, Martinistrasse 52, Hamburg, Germany
    Expert Opin Pharmacother 12:627-33. 2011
    ..Psychiatrists should reconsider their negative attitudes toward long-acting or depot antipsychotics and should offer this administration to the majority of patients, not only to a negatively selected population...
  8. ncbi Long-term phase of schizophrenia: impact of atypical agents
    D Naber
    Universitat Hamburg, Germany
    Int Clin Psychopharmacol 15:S11-4. 2000
    ..This is associated with alleviation of negative symptoms and cognitive deficits, benefits which are not seen with traditional agents and which increase the likelihood of successful rehabilitation...
  9. ncbi Aripiprazole: a new atypical antipsychotic with a different pharmacological mechanism
    Dieter Naber
    Department of Psychiatry and Psychotherapy, Universitatsklinikum Hamburg Eppendorf, Martinistrasse 52, Hamburg 20246, Germany
    Prog Neuropsychopharmacol Biol Psychiatry 28:1213-9. 2004
    ..However, only post-marketing experience will show whether the positive results of these controlled trials can be replicated in everyday practice...
  10. ncbi [Subjective well-being under antipsychotic treatment and its meaning for compliance and course of disease]
    Dieter Naber
    Universitatsklinikum Hamburg Eppendorf, Klinik fur Psychiatrie und Psychotherapie
    Psychiatr Prax 31:S230-2. 2004
    ....
  11. ncbi Tools for measuring clinical effectiveness
    Dieter Naber
    Department of Psychiatry and Psychotherapy, University of Hamburg, Hamburg, Germany
    Eur Neuropsychopharmacol 14:S435-44. 2004
    ..If this approach to evaluating treatment outcomes is adopted, clinicians will be better placed to differentiate therapeutic interventions on the basis of clinical effectiveness...
  12. ncbi Good tolerability equals good results: the patient's perspective
    D Naber
    Hospital of Psychiatry and Psychotherapy, University of Hamburg, Martinistrasse 52, D 20247 Hamburg, Germany
    Eur Neuropsychopharmacol 11:S391-6. 2001
    ....
  13. ncbi Remission and recovery and their predictors in schizophrenia spectrum disorder: results from a 1-year follow-up naturalistic trial
    Rebecca Schennach
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University Munich, Nussbaumstrasse 7, 80336, Munich, Germany
    Psychiatr Q 83:187-207. 2012
    ..0113) were found to be significantly predictive of recovery. Our results underline the need to implement more specific treatment strategies to improve long-term outcome...
  14. ncbi Response trajectories in "real-world" naturalistically treated schizophrenia patients
    Rebecca Schennach
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
    Schizophr Res 139:218-24. 2012
    ..To date, research has identified distinct antipsychotic response trajectories yet focussing on data from randomized-controlled trials (RCTs). Therefore, the heterogeneity of response in "real-world" schizophrenia patients is still unknown...
  15. ncbi Predictors of relapse in the year after hospital discharge among patients with schizophrenia
    Rebecca Schennach
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Nussbaumstreet 7, 80336 Munich, Germany
    Psychiatr Serv 63:87-90. 2012
    ..Relapse and its predictors were examined among patients with schizophrenia in the year after hospital discharge...
  16. ncbi Quality of life and subjective well-being in schizophrenia and schizophrenia spectrum disorders: valid predictors of symptomatic response and remission?
    Rebecca Schennach-Wolff
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
    World J Biol Psychiatry 11:729-38. 2010
    ..To examine quality of life and subjective well-being as predictors of symptomatic treatment outcome...
  17. ncbi Evaluating depressive symptoms in schizophrenia: a psychometric comparison of the Calgary Depression Scale for Schizophrenia and the Hamilton Depression Rating Scale
    Rebecca Schennach
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
    Psychopathology 45:276-85. 2012
    ....
  18. ncbi Attitude towards adherence in patients with schizophrenia at discharge
    Rebecca Schennach-Wolff
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Nussbaumstr 7, 80336 Munich, Germany
    J Psychiatr Res 43:1294-301. 2009
    ....
  19. ncbi Long-term patterns of subjective wellbeing in schizophrenia: cluster, predictors of cluster affiliation, and their relation to recovery criteria in 2842 patients followed over 3 years
    Martin Lambert
    Psychosis Centre, Centre for Psychosocial Medicine, Department of Psychiatry and Psychotherapy, University Medical Center Hamburg Eppendorf, Germany
    Schizophr Res 107:165-72. 2009
    ....
  20. ncbi Brief Psychiatric Rating Scale - Excited Component (BPRS-EC) and neuropsychological dysfunction predict aggression, suicidality, and involuntary treatment in first-episode psychosis
    Christian G Huber
    Department of Psychiatry and Psychotherapy, Centre for Psychosocial Medicine, University Medical Centre Hamburg Eppendorf, Martinistr 52, D 20246 Hamburg, Germany
    Schizophr Res 134:273-8. 2012
    ..Although there are studies on prevalence and clinical predictors of these conditions, little is known on the influence of psychopathology and neuropsychological dysfunction...
  21. ncbi Characterization of the facial expression of emotions in schizophrenia patients: preliminary findings with a new electromyography method
    Karsten Wolf
    Department of Psychiatry and Psychotherapy, University Hospital of Hamburg, Germany
    Can J Psychiatry 51:335-41. 2006
    ..We investigated facial expression of emotions (FEE) in schizophrenia patients, using an improved and highly selective facial electromyography (EMG) method, and we examined the correlation between FEE and psychopathology...
  22. ncbi Does clinical judgment of baseline severity and changes in psychopathology depend on the patient population? Results of a CGI and PANSS linking analysis in a naturalistic study
    Rebecca Schennach-Wolff
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University Munich, Munich, Germany
    J Clin Psychopharmacol 30:726-31. 2010
    ..Furthermore, these linking results were compared with those derived from randomized controlled trials to examine if the baseline severity might influence the linking results...
  23. ncbi Cost-effectiveness of 12-month therapeutic assertive community treatment as part of integrated care versus standard care in patients with schizophrenia treated with quetiapine immediate release (ACCESS trial)
    Anne Karow
    Department of Psychiatry and Psychotherapy, Psychosis Centre, Centre for Psychosocial Medicine, University Medical Center Hamburg Eppendorf, Germany
    J Clin Psychiatry 73:e402-8. 2012
    ..ACT was specifically developed for patients with schizophrenia, delivered by psychosis experts highly trained in respective psychotherapies, and embedded into an integrated care system...
  24. ncbi Considering DSM-5: personality diagnostics in patients with schizophrenia spectrum disorders
    Katrin Schroeder
    Department of Psychiatry and Psychotherapy, University Medical Centre Hamburg Eppendorf, Hamburg, Germany
    Psychiatry 75:120-34. 2012
    ..SSD psychopathology may bias PD diagnostics and lead to a higher percentage of categorical PD diagnoses, especially considering the proposed changes in DSM-5...
  25. ncbi Validation of a Clinical Global Impression Scale for Aggression (CGI-A) in a sample of 558 psychiatric patients
    Christian G Huber
    Psychosis Early Detection and Intervention Centre, Centre for Psychosocial Medicine, Department of Psychiatry and Psychotherapy, University Medical Centre Hamburg Eppendorf, Germany
    Schizophr Res 100:342-8. 2008
    ..Clinical management of aggression depends on the availability of easily administrable measurements allowing reliable evaluation. The present study's aim is to validate a Clinical Global Impression-Severity of Aggression scale (CGI-A)...
  26. ncbi Association of subjective well-being, symptoms, and side effects with compliance after 12 months of treatment in schizophrenia
    Anne Karow
    Center for Psychosocial Medicine, Department of Psychiatry and Psychotherapy, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    J Clin Psychiatry 68:75-80. 2007
    ....
  27. ncbi Differential 3-year effects of first- versus second-generation antipsychotics on subjective well-being in schizophrenia using marginal structural models
    Martin Lambert
    Psychosis Centre, Department of Psychiatry and Psychotherapy, Centre for Psychosocial Medicine, University Medical Centre Hamburg Eppendorf, Germany
    J Clin Psychopharmacol 31:226-30. 2011
    ..This study examined the differential effects of first- (FGAs) versus second-generation antipsychotics (SGAs) on subjective well-being in patients with schizophrenia...
  28. ncbi Physical and mental health in severe opioid-dependent patients within a randomized controlled maintenance treatment trial
    Jens Reimer
    Centre for Interdisciplinary Addiction Research, University of Hamburg, Hamburg, Germany
    Addiction 106:1647-55. 2011
    ..To evaluate physical and mental health and compare treatment outcomes in opiate-dependent patients substituted either with heroin or methadone...
  29. ncbi Subjective wellbeing under quetiapine treatment: effect of diagnosis, mood state, and anxiety
    Martin Lambert
    Psychosis Early Detection and Intervention Centre PEDIC, Centre for Psychosocial Medicine, Department of Psychiatry, University Medical Center Hamburg Eppendorf, Germany
    Schizophr Res 110:72-9. 2009
    ..To examine the effect of diagnosis, mood state, and anxiety on subjective wellbeing in patients with affective and non-affective psychotic disorders treated with quetiapine IR...
  30. ncbi Childhood trauma and dissociation in female patients with schizophrenia spectrum disorders: an exploratory study
    Ingo Schafer
    Klinik fur Psychiatrie und Psychotherapie, Universitätsklinik Hamburg Eppendorf, Hamburg, Germany
    J Nerv Ment Dis 194:135-8. 2006
    ..Our results confirm the relevance of childhood trauma in schizophrenic patients but also demonstrate the need to develop appropriate methodologies for measuring dissociation in this population...
  31. ncbi Assertive community treatment as part of integrated care versus standard care: a 12-month trial in patients with first- and multiple-episode schizophrenia spectrum disorders treated with quetiapine immediate release (ACCESS trial)
    Martin Lambert
    Psychosis Centre, Department for Psychiatry and Psychotherapy, Centre for Psychosocial Medicine, University Medical Center Hamburg Eppendorf, Martinistr 52, 20246 Hamburg, Germany
    J Clin Psychiatry 71:1313-23. 2010
    ....
  32. ncbi [Subjective view of positive symptoms and quality of life in patients with schizophrenia]
    Anne Karow
    Zentrum fur Psychosoziale Medizin, Klinik fur Psychiatrie und Psychotherapie, Universitatsklinikum Hamburg Eppendorf, Hamburg
    Psychiatr Prax 35:286-93. 2008
    ..The aim of the study was the investigation of positive symptoms and quality of life from the subjective perspective of patients with schizophrenia...
  33. ncbi Management of incomplete remission and treatment resistance in first-episode psychosis
    Martin Lambert
    University Medical Centre Hamburg Eppendorf, Psychosis Early Detection and Intervention Centre, Centre for Psychosocial Medicine, Department of Psychiatry and Psychotherapy, Martinistreet 52, D 20246 Hamburg, Germany
    Expert Opin Pharmacother 9:2039-51. 2008
    ..Incomplete remission and treatment resistance are common even in first-episode psychosis patients...
  34. ncbi Remission in schizophrenia: validity, frequency, predictors, and patients' perspective 5 years later
    Martin Lambert
    Psychosis Centre, Department of Psychiatry and Psychotherapy, Center for Psychosocial Medicine, University Medical Center Hamburg Eppendorf, German
    Dialogues Clin Neurosci 12:393-407. 2010
    ..Future research should therefore search for criteria of these dimensions and test whether the RSWG remission criteria consistently predict a "good" outcome with respect to functioning and quality of life...
  35. ncbi Establishing remission and good clinical functioning in schizophrenia: predictors of best outcome with long-term risperidone long-acting injectable treatment
    M Lambert
    Psychosis Centre, Department of Psychiatry and Psychotherapy, Centre for Psychosocial Medicine, University Medical Center Hamburg Eppendorf Hamburg, Martinistreet 52, 20246 Hamburg, Germany
    Eur Psychiatry 25:220-9. 2010
    ..To measure symptomatic and functional remission in patients treated with risperidone long-acting injectable (RLAI)...
  36. ncbi The impact of subjective well-being under neuroleptic treatment on compliance and remission
    Walter de Millas
    Centre for Psychosocial Medicine, Department for Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
    Dialogues Clin Neurosci 8:131-6. 2006
    ..The data strongly suggest that a systematic evaluation of the patient's perspective of antipsychotic treatment is meaningful and necessary to increase compliance, functional outcome, and long-term prognosis...
  37. ncbi Effectiveness, tolerability, and safety of ziprasidone in patients with schizophrenia or schizoaffective disorder: results of a multi-centre observational trial
    Duerten Kudla
    Centre for Psychosocial Medicine, Department of Psychiatry and Psychotherapy, University Medical Center Hamburg Eppendorf, Martinistr 52, 20246 Hamburg, Germany
    Eur Psychiatry 22:195-202. 2007
    ..Secondary objectives included quality of life, subjective well-being, tolerability, and safety...
  38. ncbi How to treat the untreated: effectiveness of a self-help metacognitive training program (myMCT) for obsessive-compulsive disorder
    Steffen Moritz
    University Medical Center Hamburg Eppendorf, Department of Psychiatry and Psychotherapy, Hamburg, Germany
    Dialogues Clin Neurosci 12:209-20. 2010
    ..63), particularly for obsessions (d= .69). Medium to strong differences emerged for the OCI-R (d = .70) and the BDI-SF (d = .50). The investigation provides the first evidence for the effectiveness of the myMCT for OCD...
  39. ncbi Objective and subjective efficacy as well as tolerability of olanzapine in the acute treatment of 120 patients with schizophrenia spectrum disorders
    Martin Lambert
    Department for Psychiatry and Psychotherapy, University of Hamburg, Martinistrasse 52, 20246 Hamburg, Germany
    Int Clin Psychopharmacol 18:251-60. 2003
    ..The results underline the need of Phase IV studies for the assessment of clinical antipsychotic efficacy and tolerability...
  40. ncbi Comorbidity of schizophrenia and galactosemia: effective clozapine treatment with weight gain
    Christian Haasen
    Department of Psychiary and Psychotherapy, University Hospital Eppendorf, Hamburg, Germany
    Int Clin Psychopharmacol 18:113-5. 2003
    ....
  41. ncbi Early onset of treatment effects with oral risperidone
    Thomas J Raedler
    Department of Psychiatry, University Medical Center Hamburg Eppendorf, Martinistr, 52, 20246 Hamburg, Germany
    BMC Psychiatry 7:4. 2007
    ..However, recent studies have challenged this concept. We therefore performed an analysis of the onset of antipsychotic treatment effects in a sample of acutely decompensated patients with schizophrenia...
  42. ncbi Defining and predicting functional outcome in schizophrenia and schizophrenia spectrum disorders
    Rebecca Schennach-Wolff
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
    Schizophr Res 113:210-7. 2009
    ..To assess criteria and to identify predictive factors for functional outcome. The criteria should cover all domains proposed by the Remission in Schizophrenia Working Group...
  43. ncbi Prediction of remission as a combination of symptomatic and functional remission and adequate subjective well-being in 2960 patients with schizophrenia
    Martin Lambert
    Psychosis Early Detection and Intervention Centre PEDIC, Centre for Psychosocial Medicine, Department of Psychiatry and Psychotherapy, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    J Clin Psychiatry 67:1690-7. 2006
    ....
  44. ncbi 'Hyper-priming' in thought-disordered schizophrenic patients
    S Moritz
    , , Hamburg, Germany
    Psychol Med 31:221-9. 2001
    ....
  45. ncbi Rationale and baseline characteristics of PREVENT: a second-generation intervention trial in subjects at-risk (prodromal) of developing first-episode psychosis evaluating cognitive behavior therapy, aripiprazole, and placebo for the prevention of psychosi
    Andreas Bechdolf
    Department of Psychiatry and Psychotherapy, University of Cologne, Kerpener Str 62, 50924 Cologne, Germany
    Schizophr Bull 37:S111-21. 2011
    ..When the final results of the trial are available, PREVENT will substantially expand the current limited evidence base for best clinical practice in people at-risk (prodromal) of first-episode psychosis...
  46. ncbi No deficits in nonverbal memory, metamemory and internal as well as external source memory in obsessive-compulsive disorder (OCD)
    Steffen Moritz
    University Medical Center Hamburg Eppendorf, Department of Psychiatry and Psychotherapy, Hamburg, Germany
    Behav Res Ther 47:308-15. 2009
    ..We claim that research should move forward from the mere study of objective impairment to the assessment of cognitive performance in conjunction with personality traits such as inflated responsibility...
  47. ncbi Current issues in schizophrenia: overview of patient acceptability, functioning capacity and quality of life
    Martin Lambert
    Centre for Psychosocial Medicine, Department for Psychiatry and Psychotherapy, University of Hamburg, Hamburg, Germany
    CNS Drugs 18:5-17; discussion 41-3. 2004
    ..Ideally, an atypical drug which is known not to have a negative effect on attention, affect or motivation should be chosen...
  48. ncbi [On subjective meaning of psychoses. Construction, validation and first application of a new questionnaire--the SuSi-Project (Hamburg)]
    Thomas Bock
    Universitätsklinik Hamburg Eppendorf, Klinik fur Psychiatrie und Psychotherapie, Martinistrasse 52, 20246 Hamburg, Germany
    Psychiatr Prax 37:285-91. 2010
    ..A new questionnaire to assess subjective meaning in psychosis (SuSi) will be presented...
  49. ncbi Diagnostic validity of ICD-10 personality dimensions: a multitrait-multimethod analysis of two self-report questionnaires and a structured interview
    Katrin Schroeder
    Department of Psychiatry and Psychotherapy, University Medical Centre Hamburg Eppendorf, Hamburg, Germany
    Psychopathology 43:110-20. 2010
    ..There is growing evidence that the validity of diagnostic methods for personality disorders (PD) may be insufficient. Although the ICD-10 classification system is widely used, there is little data concerning its validity for diagnosing PD...
  50. ncbi Incomplete remission and treatment resistance in first-episode psychosis: definition, prevalence and predictors
    Christian G Huber
    University Medical Centre Hamburg Eppendorf, Psychosis Early Detection and Intervention Centre, Centre for Psychosocial Medicine, Department of Psychiatry and Psychotherapy, Martinistreet 52, D 20246 Hamburg, Germany
    Expert Opin Pharmacother 9:2027-38. 2008
    ..Different definitions for these terms have been used in psychiatric research, making generalized statements about the prevalence and predictors of treatment resistance difficult...
  51. ncbi [Outpatient prescription of atypical antipsychotics for schizophrenic patients after discharge from hospital treatment]
    Ingo Schafer
    Universitätsklinik Hamburg Eppendorf, Klinik fur Psychiatrie und Psychotherapie, Hamburg, Germany
    Psychiatr Prax 31:74-7. 2004
    ..However, global statistics of prescriptions are difficult to interpret. To get data of the current practice, 132 patients treated with atypical antipsychotics in a university clinic were followed-up one year later...
  52. ncbi Outcome of suicidal patients with schizophrenia: results from a naturalistic study
    R Schennach-Wolff
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
    Acta Psychiatr Scand 121:359-70. 2010
    ..Purpose was to assess suicidality before and at the time of admission in patients with schizophrenia and compare outcome differences...
  53. ncbi Differentiating schizoaffective and bipolar I disorder in first-episode psychotic mania
    Daniel Schottle
    Psychosis Early Detection and Intervention Centre PEDIC, Centre for Psychosocial Medicine, Department for Psychiatry and Psychotherapy, University Medical Centre Hamburg Eppendorf, Germany
    Schizophr Res 140:31-6. 2012
    ..This study aims to differentiate schizoaffective disorder (SAD) and bipolar-I-disorder (BD) in first-episode psychotic mania (FEPM)...
  54. ncbi Influence of atypical neuroleptics on executive functioning in patients with schizophrenia: a randomized, double-blind comparison of olanzapine vs. clozapine
    Stefan Bender
    Department of Psychiatry and Psychotherapy, University of Duisburg Essen, Germany
    Int J Neuropsychopharmacol 9:135-45. 2006
    ..However, Stroop reaction time improved with olanzapine while clozapine had a stronger effect on improving negative symptoms, thus suggestive of a differential drug effect...
  55. ncbi Adjunctive use of reboxetine in schizophrenia
    Thomas J Raedler
    University Hospital Hamburg Eppendorf, Department of Psychiatry and Psychotherapy, Martini str 52, 20246 Hamburg, Germany
    Eur Psychiatry 19:366-9. 2004
    ..We sought to study the efficacy and tolerability of the adjunctive use of reboxetine in a cohort of schizophrenic patients with prominent depressive or negative symptoms...
  56. ncbi Subjective cognitive dysfunction in first-episode and chronic schizophrenic patients
    S Moritz
    Clinic for Psychiatry and Psychotherapy, University Clinic Hamburg-Eppendorf, Hamburg, Germany
    Compr Psychiatry 42:213-6. 2001
    ..In marked contrast to a Kraepelinian view of schizophrenia, the present data confirm previous studies conducted with objective neuropsychological tests that schizophrenia is a neurodevelopmental rather than a neurodegenerative disorder...
  57. ncbi [Atypical neuroleptics in the treatment of aggression and hostility in schizophrenic patients]
    P Briken
    Zentrum fur Psychosoziale Medizin, Psychiatrie und Psychotherapie, Universitatsklinikum Hamburg Eppendorf, Germany
    Fortschr Neurol Psychiatr 70:139-44. 2002
    ..In persistent aggression clozapin shows the best specific results. Typical depot neuroleptics should be considered in cases when medication compliance is a problem...
  58. ncbi Drug safety and efficacy evaluation of sertindole for schizophrenia
    Evangelos Karamatskos
    University Medical Center Hamburg Eppendorf, Centre of Psychosocial Medicine, Department of Psychiatry and Psychotherapy, Martinistr 52, D 20246 Hamburg, Germany
    Expert Opin Drug Saf 11:1047-62. 2012
    ..g., children, elderly, first-episode, treatment-refractory patients, etc.) are still needed for a precise understanding of the therapeutic benefits and its role in schizophrenia therapy...
  59. ncbi Valuation and attainment of treatment goals in schizophrenia: perspectives of patients, relatives, physicians, and payers
    Olaf Kuhnigk
    University Medical Centre Hamburg Eppendorf, Department of Psychiatry and Psychotherapy, Hamburg, Germany
    J Psychiatr Pract 18:321-8. 2012
    ..This study investigated and compared the valuation and perceived attainment of multiple treatment goals in schizophrenia from the perspectives of four different groups of stakeholders...
  60. ncbi Memory and attention performance in psychiatric patients: lack of correspondence between clinician-rated and patient-rated functioning with neuropsychological test results
    Steffen Moritz
    University Hospital Hamburg Eppendorf, Department of Psychiatry and Psychotherapy, Hamburg, Germany
    J Int Neuropsychol Soc 10:623-33. 2004
    ..Reasons for decreased sensitivity of self-reported and clinician-assessed neurocognitive functioning are discussed...
  61. ncbi Attitudes of patients with schizophrenia and depression to psychiatric research: a study in seven European countries
    Ingo Schafer
    Department of Psychiatry and Psychotherapy, University Medical Center Hamburg Eppendorf, Martinistr 52, 20246, Hamburg, Germany
    Soc Psychiatry Psychiatr Epidemiol 46:159-65. 2011
    ..Relatively few studies have examined how patients with schizophrenia and depression view psychiatric research and what influences their readiness to participate...
  62. ncbi Everyday memory functioning in obsessive- compulsive disorder
    Lena Jelinek
    Department of Psychiatry and Psychotherapy, University Medical Center Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
    J Int Neuropsychol Soc 12:746-9. 2006
    ..1). According to norm values, memory performance was unimpaired in most OCD patients. The present findings further challenge a broad account of the "memory deficit" hypothesis of OCD and compulsive checking, respectively...
  63. ncbi ["Anti-stigma campaign from below" at schools--experience of the initiative "Irre menschlich Hamburg e.V."]
    Thomas Bock
    Klinik fur Psychiatrie und Psychotherapie, Universitätsklinik Hamburg Eppendorf
    Psychiatr Prax 30:402-8. 2003
    ..The more health politically based motives of the anti-stigma work have meanwhile been completed by educational justifications. This way of open meeting is also being discussed as a completion to the symptom based early diagnosis...
  64. ncbi Depression in Alzheimer's disease might be associated with apolipoprotein E epsilon 4 allele frequency in women but not in men
    Thomas Müller-Thomsen
    Department of Psychiatry and Psychotherapy, University of Hamburg, Germany
    Dement Geriatr Cogn Disord 14:59-63. 2002
    ..This effect remained stable in stepwise regression analysis when depression as the dependent variable was tested against the independent variables age, age of onset, duration of disease, cognitive status and years of school education...
  65. ncbi [Treatment resistant schizophrenia, residual subtype: symptom improvement after additional treatment with amisulpride]
    Karsten Wolf
    Universitatsklinikum Hamburg Eppendorf, Klinik und Poliklinik fur Psychiatrie und Psychotherapie
    Psychiatr Prax 33:42-4. 2006
    ..Therapy resistant, severe residual schizophrenia poses major challenges for the psychiatric pharmacological treatment...
  66. ncbi Neurocognitive performance in first-episode and chronic schizophrenic patients
    Steffen Moritz
    University Hospital of Hamburg, Hospital for Psychiatry and Psychotherapy, Germany
    Eur Arch Psychiatry Clin Neurosci 252:33-7. 2002
    ..It is suggested that neuropsychological disturbances occur early in schizophrenia and do not worsen in the course beyond age-related decrement. Possible reasons why previous research has produced contradictory findings are discussed...
  67. ncbi Rates and predictors of remission and recovery during 3 years in 392 never-treated patients with schizophrenia
    M Lambert
    Psychosis Early Detection and Intervention Centre, Centre for Psychosocial Medicine, Department of Psychiatry and Psychotherapy, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Acta Psychiatr Scand 118:220-9. 2008
    ..Few studies have prospectively examined remission and recovery as well as their predictors in schizophrenia simultaneously. Aims of the study were to identify remission and recovery rates as well as their predictors in schizophrenia...
  68. ncbi Treatment of severe agitation with olanzapine in 166 patients with schizophrenia, schizoaffective, or bipolar I disorder
    M Lambert
    Psychosis Early Detection and Intervention Centre PEDIC, Centre for Psychosocial Medicine, Department of Psychiatry and Psychotherapy, University Medical Centre, Hamburg Eppendorf, Germany
    Pharmacopsychiatry 41:182-9. 2008
    ..Agitation is a common phenomenon in schizophrenia or acute mania. Because of the inability of patients to give informed consent in such situations, data from consenting studies are limited...
  69. ncbi The dilemma of insight into illness in schizophrenia: self- and expert-rated insight and quality of life
    A Karow
    Department for Psychiatry und Psychotherapy, University Hospital Hamburg Eppendorf, Hamburg, Germany
    Eur Arch Psychiatry Clin Neurosci 258:152-9. 2008
    ..It was hypothesised that patients with greater self- and expert-rated insight into illness report lower QOL compared to patients with poor insight...
  70. ncbi Early- and delayed antipsychotic response and prediction of outcome in 528 severely impaired patients with schizophrenia treated with amisulpride
    M Lambert
    Psychosis Early Detection and Intervention Centre PEDIC, Department of Psychiatry and Psychotherapy, Centre for Psychosocial Medicine, University Medical Center Hamburg Eppendorf
    Pharmacopsychiatry 42:277-83. 2009
    ..Limiting factors of these studies include the restriction on symptomatic outcome, the inclusion of mostly moderately ill patients, and the use of various antipsychotics...
  71. ncbi [Sex-specific differences in schizophrenia]
    T J Rädler
    Universitatsklinikum Hamburg Eppendorf, Klinik und Poliklinik fur Psychiatrie und Psychotherapie
    MMW Fortschr Med 149:32-4. 2007
    ..Women who undergo pharmacological therapy of schizophrenia have a higher drug serum level at the same dose and a higher risk of developing certain side effects, such as hyperprolactinaemia...
  72. ncbi What would the patient choose? Subjective comparison of atypical and typical neuroleptics
    A Karow
    University Hospital Hamburg Eppendorf, Department of Psychiatry und Psychotherapy
    Pharmacopsychiatry 39:47-51. 2006
    ..The aim of this study was to compare atypical and typical neuroleptics from the patient's perspective...
  73. ncbi Subjective well-being and initial dysphoric reaction under antipsychotic drugs - concepts, measurement and clinical relevance
    M Lambert
    Centre for Psychosocial Medicine, Department for Psychiatry and Psychotherapy, University of Hamburg, Hamburg, Germany
    Pharmacopsychiatry 36:S181-90. 2003
    ..This article reviews existing literature in order to approach relevant questions for pharmacotherapy...
  74. ncbi Cognitive dysfunction at baseline predicts symptomatic 1-year outcome in first-episode schizophrenics
    S Moritz
    Universitäts Krankenhaus Hamburg Eppendorf, Klinik fur Psychiatrie und Psychotherapie, Hamburg, Deutschland
    Psychopathology 33:48-51. 2000
    ..005). It is suggested that the exploration and treatment of neuropsychological deficits in schizophrenia is of great clinical importance with regard to its impact on both functional and symptomatic outcome in schizophrenia...
  75. ncbi [Treatment oriented to subjective well- being rather than symptom amelioration "at all costs"--paradigm change in treatment with antipsychotics]
    A Karow
    Klinik fur Psychiatrie und Psychotherapie, Universitatsklinikum Hamburg Eppendorf
    MMW Fortschr Med 147:44-5. 2005
    ..With this approach, the physician-patient relationship, compliance and the long-term prognosis can all be appreciably improved...
  76. ncbi Comparison of olanzapine and risperidone in 367 first-episode patients with non-affective or affective psychosis: results of an open retrospective medical record study
    M Lambert
    Department of Psychiatry and Psychotherapy, University of Hamburg, Martini Street 52, 20246 Hamburg, Germany
    Pharmacopsychiatry 38:206-13. 2005
    ..Previous studies comparing olanzapine (OLZ) and risperidone (RIS) have tended to focus on multiple-episode patients, with no studies examining their comparative efficacy in a non-selective sample of first-episode psychosis...
  77. ncbi [Identification of possible cognizance parameters of "mimic disintegration" in schizophrenia using facial electromyography]
    K Wolf
    Klinik und Poliklinik fur Psychiatrie und Psychotherapie, Universitätsklinikum Hamburg Eppendorf Deutschland
    Nervenarzt 76:1103-4, 1105-8. 2005
    ..We suggest further examination of the two mimic disintegration signs regarding other emotions, necessarily including more facial muscles in the testing...
  78. ncbi The impact of substance use disorders on clinical outcome in 643 patients with first-episode psychosis
    M Lambert
    Centre for Psychosocial Medicine, Department of Psychiatry and Psychotherapy, Psychosis Early Detection and Intervention Centre PEDIC, University Hospital Hamburg Eppendorf, Hamburg, Germany
    Acta Psychiatr Scand 112:141-8. 2005
    ..The main aim of the present study was to assess the impact of baseline SUD and course of SUD on remission of positive symptoms...
  79. ncbi Olanzapine vs. other antipsychotics in actual out-patient settings: six months tolerability results from the European Schizophrenia Out-patient Health Outcomes study
    M Lambert
    Centre for Psychosocial Medicine, Department for Psychiatry and Psychotherapy, University Hospital Hamburg Eppendorf, Hamburg, Germany
    Acta Psychiatr Scand 111:232-43. 2005
    ..The European Schizophrenia Out-patient Health Outcomes study is an observational study investigating treatment in schizophrenia. We report treatment-emergent adverse events during the first 6 months of treatment...
  80. ncbi Impact of present and past antipsychotic side effects on attitude toward typical antipsychotic treatment and adherence
    M Lambert
    Centre for Psychosocial Medicine, Department for Psychiatry and Psychotherapy, University of Hamburg, Martini Street 52, 20246 Hamburg, Germany
    Eur Psychiatry 19:415-22. 2004
    ....
  81. ncbi [Atypical antipsychotics in therapy refractory schizophrenia]
    I Schafer
    Klinik für Psychiatrie und Psychoterapie der Universitätsklinik Hamburg Eppendorf
    Nervenarzt 75:79-91. 2004
    ..Case studies also indicate the efficacy of combining different atypical antipsychotics, but no systematic research on this issue has been done so far...
  82. ncbi Gender-specific effects in the treatment of acute schizophrenia with risperidone
    T J Raedler
    Department of Psychiatry, University Hospital Hamburg Eppendorf, Martinistr 52, 20246 Hamburg, Germany
    Pharmacopsychiatry 39:171-4. 2006
    ..We have now reanalysed the clinical data to assess the effects of gender on treatment and outcome...
  83. ncbi Remission of severely impaired subjective wellbeing in 727 patients with schizophrenia treated with amisulpride
    M Lambert
    Psychosis Early Detection and Intervention Centre PEDIC, Centre for Psychosocial Medicine, Department of Psychiatry and Psychotherapy of the University Hospital Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
    Acta Psychiatr Scand 115:106-13. 2007
    ..Studies of subjective wellbeing (SW) in schizophrenia have missed to define and to assess rate and predictors of SW response (SW-res) and SW remission (SW-rem)...
  84. ncbi Neuropsychological correlates of schizophrenic syndromes in patients treated with atypical neuroleptics
    S Moritz
    Universitäts Krankenhaus Hamburg Eppendorf, Klinik fur Psychiatrie und Psychotherapie, Martinistrasse 52, D 20246, Hamburg, Germany
    Eur Psychiatry 16:354-61. 2001
    ..Previous findings reporting correlations between negative symptomatology and neurocognition may have been confounded by the adverse consequences of typical neuroleptics...
  85. ncbi Enhanced semantic priming in thought-disordered schizophrenic patients using a word pronunciation task
    S Moritz
    Universitäts Krankenhaus Hamburg Eppendorf, Klinik fur Psychiatrie und Psychotherapie, Martinistrasse 52, D 20246 Hamburg, Germany
    Schizophr Res 48:301-5. 2001
    ..Results were not moderated by sociodemographic background variables, psychomotor slowing and psychopathological symptoms other than thought disorder...
  86. ncbi [Open studies in comparison to controlled studies in testing of neuroleptics]
    F G Pajonk
    Klinik fur Psychiatrie und Psychotherapie, Universitätskrankenhaus Hamburg Eppendorf
    Fortschr Neurol Psychiatr 68:313-20. 2000
    ..Aim of this study was to investigate if results of an open or double-blind approach differ and hereby to gain information about the validity of open trials...
  87. ncbi [Conversion from typical to atypical neuroleptics. Guidelines for ambulatory and inpatient treatment]
    M Lambert
    Klinik für Psychiatrie und Psychotherapie der Universität Hamburg
    Nervenarzt 71:859-75. 2000
    ..The present article addresses guidelines for the conversion from conventional to atypical neuroleptics in inpatient and outpatient settings...
  88. ncbi Negative priming in schizophrenia: effects of masking and prime presentation time
    S Moritz
    Universitäts Krankenhaus Hamburg Eppendorf, Klinik fur Psychiatrie und Psychotherapie, Martinistrasse 52, D 20246 Hamburg, Germany
    Schizophr Res 48:291-9. 2001
    ..Results strongly suggest that reduced negative priming in schizophrenics may not be due to reduced cognitive inhibition but mirrors perceptual deficits...
  89. ncbi A test of concordance between patient and psychiatrist valuations of multiple treatment goals for schizophrenia
    John F P Bridges
    Assistant Professor, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA Manager, Health Economics, Janssen Cilag GmbH, Neuss, Germany Associate Professor Professor Manager, Department of Psychiatry and Psychotherapy, University Medical Centre Hamburg Eppendorf, Hamburg, Germany
    Health Expect 16:164-76. 2013
    ..This study also demonstrates the importance of comparing the concordance in treatment goals and the importance of preference-based methods, such as the self-explicated method, in the study of concordance...
  90. ncbi Risperidone in the treatment of acute schizophrenia
    Thomas J Raedler
    Department of Psychiatry, University Hospital Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
    J Clin Psychopharmacol 24:335-8. 2004
    ..To evaluate the efficacy of the atypical antipsychotic risperidone, we conducted an open-label observational study among admissions to a secure unit...
  91. ncbi The facial pattern of disgust, appetence, excited joy and relaxed joy: an improved facial EMG study
    Karsten Wolf
    Department of Psychiatry and Psychotherapy, University Hospital Hamburg Eppendorf, Germany
    Scand J Psychol 46:403-9. 2005
    ..Our findings indicate the possibility to explore the entire emotion system successfully through a state-of-the-art psychophysiological method like our EMG device...
  92. ncbi Comparing the efficacy of atypical antipsychotics in open uncontrolled versus double-blind controlled trials in schizophrenia
    Frank Gerald Pajonk
    Department of Psychiatry and Psychotherapy, University Hospital Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
    Psychopharmacology (Berl) 162:29-36. 2002
    ..The aim of this study was to investigate whether results of open and double-blind approaches differ and thereby gain information about the validity of open trials...
  93. ncbi Psychopharmacological treatment of aggression in schizophrenic patients
    T Brieden
    Department of Psychiatry and Psychotherapy, Hamburg-Eppendorf University Hospital, Germany
    Pharmacopsychiatry 35:83-9. 2002
    ..In addition, we will briefly present studies and case reports concerning the treatment of aggression in other psychiatric patients...
  94. ncbi Subjective well-being and quality of life under atypical antipsychotic treatment
    A Karow
    University Hospital Hamburg Eppendorf, Department of Psychiatry and Psychotherapy, Martinistrasse 52, 20246 Hamburg, Germany
    Psychopharmacology (Berl) 162:3-10. 2002
    ..Furthermore, the benefit of introducing atypical antipsychotics early in the course of illness and their particular benefit in combination with rehabilitative non-pharmacological treatment is discussed...
  95. ncbi Suicides and suicide attempts in emergency medicine
    Frank Gerald Pajonk
    Department of Psychiatry and Psychotherapy, University Hospital Hamburg Eppendorf, Germany
    Crisis 23:68-73. 2002
    ..This investigation presents a first evaluation of the complete emergency protocols from a major German city focusing on suicide and parasuicide...
  96. ncbi Heroin-assisted treatment for opioid dependence: randomised controlled trial
    Christian Haasen
    Centre for Interdisciplinary Addiction Research, Department of Psychiatry, University Medical Centre Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
    Br J Psychiatry 191:55-62. 2007
    ..Heroin-assisted treatment has been found to be effective for people with severe opioid dependence who are not interested in or do poorly on methadone maintenance...
  97. ncbi Switching to amisulpride due to hepatic complications
    Oktay Yagdiran
    University Hospital Eppendorf, Clinic for Psychiatry and Psychotherapy, Martinistr. 52, 20246, Hamburg, Germany
    Eur Psychiatry 17:170-1. 2002
  98. ncbi CSF-tau, CSF-Abeta1-42, ApoE-genotype and clinical parameters in the diagnosis of Alzheimer's disease: combination of CSF-tau and MMSE yields highest sensitivity and specificity
    S Ganzer
    Department of Psychiatry and Psychotherapy, University Hospital Hamburg Eppendorf, Hamburg, Germany
    J Neural Transm 110:1149-60. 2003
    ..CSF-Abeta1-42 showed no additional benefit in discriminating patients from controls but might be useful for tracking the severity of the disease...
  99. ncbi Cinemeducation in psychiatry: a seminar in undergraduate medical education combining a movie, lecture, and patient interview
    Olaf Kuhnigk
    Dept of Psychiatry and Psychotherapy, Medical Faculty of Hamburg University, Hamburg, Germany
    Acad Psychiatry 36:205-10. 2012
    ..Psychiatric educators are often faced with students' negative attitudes toward psychiatry. A new type of seminar has been established in order to enable students to gain a deeper understanding of psychiatric illness...
  100. ncbi Trait dissociation affects the behavioral response to cholecystokinin tetrapeptide in healthy man
    Michael Kellner
    Department of Psychiatry and Psychotherapy, University Hospital Hamburg Eppendorf, Martinistrasse 52, D 20246, Hamburg, Germany
    Psychiatry Res 111:93-6. 2002
    ..Trait dissociation should be assessed in further behavioral challenge studies as a potentially important covariate...
  101. ncbi Leptin: a modulator of alcohol craving?
    F Kiefer
    Department of Psychiatry and Psychotherapy, University Hospital Hamburg, Hamburg, Germany
    Biol Psychiatry 49:782-7. 2001
    ..Leptin has been shown to regulate food intake and energy expenditure. Because leptin acts via regulation of appetite, we studied the hypothesis that suggests leptin modulates craving for alcohol as well...