Research Topics
Genomes and GenesSpecies | Thomas MussackSummaryAffiliation: University of Munich Country: Germany Publications
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Publications
[The value of magnetic resonance cholangiography for the expedient diagnosis of choledocholithiasis]Thomas Mussack
Chirurgische Klinik und Poliklinik Innenstadt, Germany
Dtsch Med Wochenschr 127:786-90. 2002....
Assessment of early brain damage in carotid endarterectomy: evaluation of S-100B serum levels and somatosensory evoked potentials in a pilot studyThomas Mussack
Department of Surgery Innenstadt, Klinikum der Universitat Munchen, Nussbaumstrasse 20, D 80336 MUnchen, Germany
World J Surg 26:1251-5. 2002..In contrast, persistently elevated S-100B serum levels seem to be associated with transient loss of SSEP and development of neurological deficits...
[Chronic appendicitis as an independent clinical entity]T Mussack
Chirurgische Klinik und Poliklinik Innenstadt, Klinikum der Universitat Munchen, Nussbaumstrasse 20, 80336 Munchen
Chirurg 73:710-5. 2002..The objectives of this prospective study were to analyse the incidence of chronic appendicitis among our patients, to compare demographic and clinical data with histological results and to evaluate long-term follow-up after appendectomy...
Rapid measurement of S-100B serum protein levels by Elecsys S100 immunoassay in patients undergoing carotid artery stenting or endarterectomyThomas Mussack
Department of Surgery Innenstadt, Klinikum der Universitat Munchen, Nussbaumstrasse 20, D 80336 Munich, Germany
Clin Biochem 39:349-56. 2006..This study was designed to apply the rapid Elecsys S100 immunoassay for real-time measurement of S100 protein serum levels indicating acute brain damage in patients undergoing carotid artery stenting (CAS) or endarterectomy (CEA)...
Serum S-100B and interleukin-8 as predictive markers for comparative neurologic outcome analysis of patients after cardiac arrest and severe traumatic brain injuryThomas Mussack
Chirurgische Klinik und Poliklinik Innenstadt, Klinikum der Universitat Munchen, Munich, Germany
Crit Care Med 30:2669-74. 2002..In both collectives, increased S-100B values measured 12 hrs after insult correlated well with an unfavorable neurologic outcome after 12 months...
Effect of stress doses of hydrocortisone on S-100B vs. interleukin-8 and polymorphonuclear elastase levels in human septic shockThomas Mussack
Department of Surgery Innenstadt, Klinikum der Universitat Munchen, Munich, Germany
Clin Chem Lab Med 43:259-68. 2005..For the first time, a similar extent of S-100B increase in serum of septic patients at the time of diagnosis was shown as reported for cardiac arrest or severe traumatic brain injury...
Significance of Elecsys S100 immunoassay for real-time assessment of traumatic brain damage in multiple trauma patientsThomas Mussack
Department of Surgery Innenstadt, Klinikum der Universitat Munchen, Munich, Germany
Clin Chem Lab Med 44:1140-5. 2006..The objective of this study was to measure early S100 levels using the Elecsys S100 immunoassay for real-time assessment of severe TBI in multiple trauma...
Serum S-100B protein levels during and after successful carotid artery stenting or carotid endarterectomyThomas Mussack
Department of General Surgery, Klinikum der Universitat Munchen, Germany
J Endovasc Ther 13:39-46. 2006....
Serum S-100B concentration provides additional information fot the indication of computed tomography in patients after minor head injury: a prospective multicenter studyPeter Biberthaler
Chirurgische Klinik und Poliklinik Innenstadt, Ludwig Maximilians Universitat Munchen, Nussbaumstrasse 20, 80336 Munchen, Germany
Shock 25:446-53. 2006..A prospective study of the clinical value of S-100B measurement in such patients is now under way...
Prolonged zona glomerulosa insufficiency causing hyperkalemia in primary aldosteronism after adrenalectomyEvelyn Fischer
Medizinische Klinik und Poliklinik IV, Klinikum der Universitat Munchen, Ziemssenstr 1, 80336 Munchen, Germany
J Clin Endocrinol Metab 97:3965-73. 2012..Unilateral adrenalectomy is the therapy of choice in aldosterone-producing adenoma (APA). Zona glomerulosa (ZG) insufficiency causing hyperkalemia after adrenalectomy has been described in case reports...
Cyanoacrylate glue for intra-abdominal mesh fixation of polypropylene-polyvinylidene fluoride meshes in a rabbit modelRoland Ladurner
Department of Surgery Innenstadt, University of Munich LMU, Munich, Germany
J Surg Res 167:e157-62. 2011..The aim of this study was to evaluate the efficacy of cyanoacrylates glue for polypropylene-polyvinylidene fluoride (PP-PVDF) intraperitoneal onlay mesh (IPOM) fixation in a rabbit model...
Cerebral perfusion pressure for prediction of recurrent intracranial hypertension after primary decompressive craniectomyThomas Mussack
Department of Surgery Innenstadt, Klinikum der Universitat Munchen, Nussbaumstrasse 20, D 80336 Munich, Germany
Eur J Med Res 10:426-33. 2005....
Role of toll-like receptor 3, RIG-I, and MDA5 in the expression of mesothelial IL-8 induced by viral RNAMarkus Wornle
Medical Policlinic, Ludwig Maximilians University, Pettenkoferstrasse 8a, 80336 Munich, Germany
Appl Biochem Biotechnol 160:1179-87. 2010....
Intrathecal and systemic concentration of NT-proBNP in patients with severe traumatic brain injuryChlodwig Kirchhoff
Chirurgische Klinik und Poliklinik, Klinikum Innenstadt, Ludwig Maximilians Universitaet, Munich, Germany
J Neurotrauma 23:943-9. 2006..Interestingly, NT-proBNP in CSF and serum was significantly elevated in patients exhibiting an ICP of >15 mm Hg. Further studies are currently performed to elucidate the physiologic role of NT-proBNP in TBI...
Role of the NFKB1 -94ins/delATTG promoter polymorphism in IBD and potential interactions with polymorphisms in the CARD15/NOD2, IKBL, and IL-1RN genesJurgen Glas
Chirurgische Klinik und Poliklinik Innenstadt, Munchen, Germany
Inflamm Bowel Dis 12:606-11. 2006..Furthermore, potential interactions of the -94ins/delATTG polymorphism with the IKBL and the IL-1RN genes should be determined...
Assessment of colonic transit time using MRI: a feasibility studySonja Buhmann
Department of Clinical Radiology, Campus Grosshadern, Ludwig Maximilians University, Marchioninistrasse 15, 81377, Munich, Germany
Eur Radiol 17:669-74. 2007....
Role of viral receptors TLR3, RIG-I and MDA5 in mesothelial tissue-type plasminogen activator and plasminogen activator inhibitor-1 synthesisMarkus Wornle
Medical Policlinic, Ludwig Maximillians University, Munich, Germany
Thromb Haemost 101:1128-37. 2009....
ACE inhibitor and AT1-receptor blocker attenuate the production of VEGF in mesothelial cellsMatthias Sauter
Department of Nephrology, Medizinische Poliklinik Innenstadt, Germany
Perit Dial Int 27:167-72. 2007..The present in vitro study was designed to investigate the effect of the ACE inhibitors captopril and enalapril, and the angiotensin II type 1-receptor (AT1) antagonist losartan on mesothelial VEGF synthesis...
Synthetic double-stranded RNA stimulates the expression of interferon-inducible protein 10 in human mesothelial cellsMonika Merkle
Klinikum Traunstein, Nephrology, Cuno Niggl Str 3, 83278 Traunstein, Germany
Clin Vaccine Immunol 18:176-9. 2011..A time- and dose-dependent increase in IP-10 is found upon activation of viral receptors expressed on mesothelial cells, which provides novel evidence for a link between viral infections and inflammation of serous membranes...
Novel role of toll-like receptor 3, RIG-I and MDA5 in poly (I:C) RNA-induced mesothelial inflammationMarkus Wornle
Medical Policlinic, Ludwig Maximilians University, Pettenkoferstrasse 8a, 80336, Munich, Germany
Mol Cell Biochem 322:193-206. 2009..This novel finding of functional expression of viral sensors on human MC may indicate a novel link between viral infections and mesothelial inflammation and indicates a pathophysiologic role of viral receptors in these processes...
Role of viral induced vascular endothelial growth factor (VEGF) production in pleural effusion and malignant mesotheliomaMarkus Wornle
Medical Policlinic, Ludwig Maximilians University, Munich, Germany
Cell Biol Int 33:180-6. 2009..This finding of viral induced mesothelial VEGF synthesis may indicate a novel link between viral infections and formation of pleural effusions and progression of malignant mesothelioma...
Klippel-Trenaunay syndrome with involvement of coecum and rectum: a rare cause of lower gastrointestinal bleedingThomas Mussack
Department of Surgery Innenstadt, Klinikum der Universitat Munchen, Nussbaumstrasse 20, D 80336 Munich, Germany
Eur J Med Res 9:515-7. 2004..Due to only moderate oozing at time of admission the patient was treated with oral iron supplementation so far...
Clinical management of large adrenal cystic lesionsHolger Schmid
Medizinische Poliklinik, Universitat Munchen, Pettenkoferstrasse 8a, D 80336, Munich, Germany
Int Urol Nephrol 37:767-71. 2005..En bloc adrenalectomy, preferably by a laparoscopic approach, has become the treatment of choice...
Assessment of large bowel motility by cine magnetic resonance imaging using two different prokinetic agents: a feasibility studySonja Buhmann
Department of Clinical Radiology, Klinikum Grosshadern, Ludwig Maximilians University Munich, Munich, Germany
Invest Radiol 40:689-94. 2005..We sought to assess large bowel motility, induced by 2 prokinetic agents, senna tea and erythromycin, using functional cine magnetic resonance imaging (MRI)...
Initial posttraumatic translocation of NF-kappaB and TNF-alpha mRNA expression in peripheral blood monocytes of trauma patients with multiple injuries: a pilot studyPeter Biberthaler
Chirurgische Klinik, Klinikum Innenstadt Ludwig Maximilians Universität, Munchen, Germany
Shock 22:527-32. 2004....
Polymorphisms of the lipopolysaccharide-signaling complex in inflammatory bowel disease: association of a mutation in the Toll-like receptor 4 gene with ulcerative colitisHelga Paula Török
Medizinische Klinik und Medizinische Poliklinik, Standort Innenstadt, Klinikum der Universitat Munchen, 80336 Munich, Germany
Clin Immunol 112:85-91. 2004..In conclusion, a novel association between a functional polymorphism in TLR4 and ulcerative colitis is reported. This observation underscores the importance of impaired innate immunity in inflammatory bowel disease...
[Role of S-100B for evaluation of traumatic brain injury in patients with alcohol intoxication]Thomas Mussack
Chirurgische Klinik und Poliklinik Innenstadt, Klinikum der Universitat, Munchen
Recenti Prog Med 96:77-80. 2005..Median S-100B levels of the CCT+ patients were significantly increased compared to those of the CCT- patients without being influenced by alcohol. Increased S-100B plasma levels seem to indicate a primary brain damage...
Immediate S-100B and neuron-specific enolase plasma measurements for rapid evaluation of primary brain damage in alcohol-intoxicated, minor head-injured patientsThomas Mussack
Chirurgische Klinik und Poliklinik Innenstadt, , Germany
Shock 18:395-400. 2002..Thus, in addition to routine neurological examinations, S-100B measurements immediately after admission might help to reduce CCT scans in alcohol-intoxicated patients early after MHI...
Bilateral primary adrenal non-Hodgkin's lymphoma and primary adrenocortical carcinoma--review of the literature preoperative differentiation of adrenal tumorsAlexandra Ozimek
Department of Surgery Innenstadt, University Hospital Munich, Munchen, Germany
Endocr J 55:625-38. 2008..Prognosis of patients with ACC and PAL seems to be dependant on the ability to start accurate treatment without any time delay. We propose some guidelines for diagnosis and surgical management of adrenal tumors...
Heavy-weight versus low-weight polypropylene meshes for open sublay mesh repair of incisional herniaS Schmidbauer
Department of Surgery Innenstadt, , Germany
Eur J Med Res 10:247-53. 2005..However, both types of meshes are convincing due to high tensile strength and low recurrence rates in the long-term run...
Long term outcome and quality of life after open incisional hernia repair--light versus heavy weight meshesRoland Ladurner
Department of Surgery Innenstadt, Ludwig Maximilian University of Munich, Nussbaumstrasse 20, Munich, Germany
BMC Surg 11:25. 2011..The aim of this retrospective non randomized study was to compare the quality of life in the long term follow up (> 72 month) after incisional hernia repair with "light weight"(LW) and "heavy weight"(HW) PP meshes...
Bilateral decompressive craniectomy due to intracranial hypertension during acute posttraumatic liver dysfunctionThomas Mussack
Department of Surgery Innenstadt, , Nussbaumstrasse 20, , Germany
J Trauma 58:1061-5. 2005
Hemofiltrastion does not influence early S-100B serum levels in septic shock patients receiving stress doses of hydrocortisone or placeboThomas Mussack
Department of Surgery Innenstadt, Klinikum der Universitat Munchen, Nussbaumstr 20, D 80336 MUnchen, Germany
Eur J Med Res 10:11-7. 2005..Thus, the objective of this study was to analyze the effect of continuous veno-venous hemofiltration (CVVH) on early S-100B serum levels in septic shock patients, who were treated with either stress doses of hydrocortisone or placebo...
Extraluminal gastrointestinal stromal tumour in the second portion of the duodenumThomas Mussack
Department of Surgery Inneustadt, Klinikum der Universitat Munchen, Munich, Germany
Eur J Gastroenterol Hepatol 15:1043-6. 2003..The combination of endoscopic ultrasonography and non-invasive multislice computed tomography provided an early suggestion of gastrointestinal stromal tumour...
Endovascular aneurysm repair: Treatment of choice for abdominal aortic aneurysm coincident with horseshoe kidney? Three case reports and review of literatureVolker Ruppert
Vascular Surgery, Department of Surgery Innenstadt, Klinikum der Universitat Munchen, Munich, Germany
J Vasc Surg 40:367-70. 2004....
Pneumopericardium in blunt chest trauma after high-speed motor vehicle accidentsRoland Ladurner
Department of Surgery Innenstadt, , D-80336 Munich, Germany
Am J Emerg Med 23:83-6. 2005..Tension pneumopericardium causing a life-threatening cardiac tamponade requires an immediate pericardial aspiration, the subsequent pericardial drainage via a pericardial window or emergent open subxyphoid approach to the pericardium...
The 14-bp deletion polymorphism in the HLA-G gene displays significant differences between ulcerative colitis and Crohn's disease and is associated with ileocecal resection in Crohn's diseaseJurgen Glas
Chirurgische Klinik und Poliklinik Innenstadt, Klinikum der Universitat Munchen, Munich, Germany
Int Immunol 19:621-6. 2007..As there are several partly functional polymorphisms within the promoter region potentially influencing HLA-G expression, further studies in IBD are necessary in the context of differential expression of HLA-G between UC and CD...
NOD2/CARD15 genotype influences MDP-induced cytokine release and basal IL-12p40 levels in primary isolated peripheral blood monocytesVanessa Beynon
Department of Surgery, Innenstadt, University of Munich, Germany
Inflamm Bowel Dis 14:1033-40. 2008..The 1007fs mutation results in loss of NF-kappaB activation in response to muramyl dipeptide (MDP) but has also been linked to an increased IL-1beta processing and IL-12 release...
The ATG16L1 gene variants rs2241879 and rs2241880 (T300A) are strongly associated with susceptibility to Crohn's disease in the German populationJurgen Glas
Department of Medicine II Grosshadern, University of Munich, Germany
Am J Gastroenterol 103:682-91. 2008....
Preoperative serum levels of the carcinoembryonic antigen in hereditary non-polyposis colorectal cancer compared to levels in sporadic colorectal cancerUwe Schiemann
Medizinische Klinik, Munchen, Germany
Cancer Detect Prev 29:356-60. 2005..Recent publications about serum CEA levels are based on patient groups without definite differentiation between hereditary and non-hereditary forms of colorectal cancer...
Successful treatment of cervical esophageal perforation in Behcet's disease with drainage operation and infliximabThomas Mussack
Am J Gastroenterol 98:703-4. 2003
Functional cine MRI of the abdomen for the assessment of implanted synthetic mesh in patients after incisional hernia repair: initial resultsTanja Fischer
Department of Clinical Radiology, Ludwig Maximilians University Munich, Ziemssenstrasse 1, 80336, Munich, Germany
Eur Radiol 17:3123-9. 2007..ePTFE meshes can be visualized directly, and typical complications like intestinal adhesions and abdominal wall dysmotility can be assessed reliably...
Intraoperative laparoscope augmentation for port placement and resection planning in minimally invasive liver resectionMarco Feuerstein
Department of Media Science, Graduate School of Information Science, Nagoya University, Nagoya 464 8603, Japan
IEEE Trans Med Imaging 27:355-69. 2008..The augmentation provides the surgeon with advanced visual aid for the localization of veins, arteries, and bile ducts to be divided or sealed...
