Alexander Munchau

Summary

Affiliation: University of Hamburg
Country: Germany

Publications

  1. doi request reprint Interhemispheric motor networks are abnormal in patients with Gilles de la Tourette syndrome
    Tobias Bäumer
    Department of Neurology, University Medical Centre Hamburg Eppendorf, Hamburg, Germany
    Mov Disord 25:2828-37. 2010
  2. ncbi request reprint Fatigue suppresses ipsilateral intracortical facilitation
    T Baumer
    Department of Neurology, University of Hamburg, Martinistrasse 52, 20246 Hamburg, Germany
    Exp Brain Res 146:467-73. 2002
  3. ncbi request reprint Laterality of interhemispheric inhibition depends on handedness
    T Baumer
    Department of Neurology, University of Hamburg, Martinstrasse 52, 20246 Hamburg, Germany
    Exp Brain Res 180:195-203. 2007
  4. pmc Magnetic stimulation of human premotor or motor cortex produces interhemispheric facilitation through distinct pathways
    Tobias Bäumer
    Department of Neurology, University Medical Centre Hamburg Eppendorf, Germany
    J Physiol 572:857-68. 2006
  5. ncbi request reprint Inhibitory and facilitatory connectivity from ventral premotor to primary motor cortex in healthy humans at rest--a bifocal TMS study
    T Baumer
    Department of Neurology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Clin Neurophysiol 120:1724-31. 2009
  6. ncbi request reprint Costs of control: decreased motor cortex engagement during a Go/NoGo task in Tourette's syndrome
    Gotz Thomalla
    1 Department of Neurology, University Medical Centre Hamburg Eppendorf, Hamburg, Germany
    Brain 137:122-36. 2014
  7. ncbi request reprint MEP latency shift after implantation of deep brain stimulation systems in the subthalamic nucleus in patients with advanced Parkinson's disease
    Ute Hidding
    Department of Neurology, University Medical Centre Hamburg Eppendorf, Germany
    Mov Disord 21:1471-6. 2006
  8. ncbi request reprint Imitation in patients with Gilles de la Tourette syndrome--a behavioral study
    Melanie Jonas
    Department of Neurology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Mov Disord 25:991-9. 2010
  9. doi request reprint Structural changes in the somatosensory system correlate with tic severity in Gilles de la Tourette syndrome
    Gotz Thomalla
    Department of Neurology, University Medial Center Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
    Brain 132:765-77. 2009
  10. ncbi request reprint Repeated premotor rTMS leads to cumulative plastic changes of motor cortex excitability in humans
    Tobias Bäumer
    Department of Neurology, University of Hamburg, Hamburg, Germany
    Neuroimage 20:550-60. 2003

Detail Information

Publications59

  1. doi request reprint Interhemispheric motor networks are abnormal in patients with Gilles de la Tourette syndrome
    Tobias Bäumer
    Department of Neurology, University Medical Centre Hamburg Eppendorf, Hamburg, Germany
    Mov Disord 25:2828-37. 2010
    ..Our combined TMS-DTI approach demonstrates abnormal functional interhemispheric connectivity in GTS accompanied by an altered structure-function relationship in the motor CC...
  2. ncbi request reprint Fatigue suppresses ipsilateral intracortical facilitation
    T Baumer
    Department of Neurology, University of Hamburg, Martinistrasse 52, 20246 Hamburg, Germany
    Exp Brain Res 146:467-73. 2002
    ..These results indicate interhemispheric interactions between the two motor cortices that are still effective after cessation of movements...
  3. ncbi request reprint Laterality of interhemispheric inhibition depends on handedness
    T Baumer
    Department of Neurology, University of Hamburg, Martinstrasse 52, 20246 Hamburg, Germany
    Exp Brain Res 180:195-203. 2007
    ..We hypothesize that IHI is a function of handedness perhaps reflecting predominant usage of the dominant hand, while lateralisation of thresholds and intracortical excitability are determined by other factors...
  4. pmc Magnetic stimulation of human premotor or motor cortex produces interhemispheric facilitation through distinct pathways
    Tobias Bäumer
    Department of Neurology, University Medical Centre Hamburg Eppendorf, Germany
    J Physiol 572:857-68. 2006
    ..These may correspond to elements involved in the generation of I3 and I1 waves, respectively...
  5. ncbi request reprint Inhibitory and facilitatory connectivity from ventral premotor to primary motor cortex in healthy humans at rest--a bifocal TMS study
    T Baumer
    Department of Neurology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Clin Neurophysiol 120:1724-31. 2009
    ..In macaques, intracortical electrical stimulation of ventral premotor cortex (PMv) can modulate ipsilateral primary motor cortex (M1) excitability at short interstimulus intervals (ISIs)...
  6. ncbi request reprint Costs of control: decreased motor cortex engagement during a Go/NoGo task in Tourette's syndrome
    Gotz Thomalla
    1 Department of Neurology, University Medical Centre Hamburg Eppendorf, Hamburg, Germany
    Brain 137:122-36. 2014
    ..This might enable patients with Tourette's syndrome to better suppress unwanted movements but comes at a price of behavioural deficits in other domains. ..
  7. ncbi request reprint MEP latency shift after implantation of deep brain stimulation systems in the subthalamic nucleus in patients with advanced Parkinson's disease
    Ute Hidding
    Department of Neurology, University Medical Centre Hamburg Eppendorf, Germany
    Mov Disord 21:1471-6. 2006
    ..These TMS effects need to be considered when interpreting results of excitability measurements in PD patients after implantation of STN electrodes...
  8. ncbi request reprint Imitation in patients with Gilles de la Tourette syndrome--a behavioral study
    Melanie Jonas
    Department of Neurology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Mov Disord 25:991-9. 2010
    ..Thus, movement stimuli may facilitate similar motor responses less but interfere more with different responses in these patients...
  9. doi request reprint Structural changes in the somatosensory system correlate with tic severity in Gilles de la Tourette syndrome
    Gotz Thomalla
    Department of Neurology, University Medial Center Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
    Brain 132:765-77. 2009
    ..The negative correlation between higher regional FA values and fewer tics suggests that these alterations of white matter microstructure represent adaptive reorganization of somatosensory processing in GTS...
  10. ncbi request reprint Repeated premotor rTMS leads to cumulative plastic changes of motor cortex excitability in humans
    Tobias Bäumer
    Department of Neurology, University of Hamburg, Hamburg, Germany
    Neuroimage 20:550-60. 2003
    ....
  11. ncbi request reprint Long-lasting increase in corticospinal excitability after 1800 pulses of subthreshold 5 Hz repetitive TMS to the primary motor cortex
    Alexander Peinemann
    Department of Neurology, Technische Universitat Munchen, Mohlstrasse 28, D 81675 Munich, Germany
    Clin Neurophysiol 115:1519-26. 2004
    ..To study the after effects of high-frequency repetitive transcranial magnetic stimulation (rTMS) over the primary motor cortex (M1) on corticospinal excitability...
  12. ncbi request reprint Charting the excitability of premotor to motor connections while withholding or initiating a selected movement
    Johan Kroeger
    Department of Neurology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Eur J Neurosci 32:1771-9. 2010
    ..Thus, the left premotor cortex is engaged not only in action selection but also in withholding and releasing a preselected movement generated by the right motor cortex...
  13. pmc Activity parameters of subthalamic nucleus neurons selectively predict motor symptom severity in Parkinson's disease
    Andrew Sharott
    Department of Neurophysiology and Pathophysiology, University Medical Center Hamburg Eppendorf, 20246 Hamburg, Germany, Medical Research Council Anatomical Neuropharmacology Unit, Department of Pharmacology, University of Oxford, Oxford OX1 3TH, United Kingdom, Department of Neurology, University Medical Center Hamburg Eppendorf, 20246 Hamburg, Germany, Department of Pediatric and Adult Movement Disorders and Neuropsychiatry, Institute of Neurology, University Medical Center Schleswig Holstein, Campus Lubeck, 23538 Lubeck, Germany, and Department of Neurosurgery, University Medical Centre Hamburg Eppendorf, 20246 Hamburg, Germany
    J Neurosci 34:6273-85. 2014
    ..Our results demonstrate that the occurrence of alterations in the rate and pattern of basal ganglia neurons could partly underlie the variability in parkinsonian phenotype...
  14. ncbi request reprint Inducing homeostatic-like plasticity in human motor cortex through converging corticocortical inputs
    Monika Pötter-Nerger
    Department of Neurology, Christian Albrechts University, Kiel, Germany
    J Neurophysiol 102:3180-90. 2009
    ..These results provide evidence for a homeostatic response pattern in the human M1(HAND) that integrates acute plastic changes evoked through different "input channels."..
  15. doi request reprint Effects of DBS, premotor rTMS, and levodopa on motor function and silent period in advanced Parkinson's disease
    Tobias Bäumer
    Department of Neurology, University Medical Centre Hamburg Eppendorf, Hamburg, Germany
    Mov Disord 24:672-6. 2009
    ..e., only partially reversed abnormal motor network activity...
  16. ncbi request reprint Waking up the brain: a case study of stimulation-induced wakeful unawareness during anaesthesia
    Christian K E Moll
    Department of Neurophysiology and Pathophysiology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Prog Brain Res 177:125-45. 2009
    ....
  17. ncbi request reprint Functional connectivity of the human premotor and motor cortex explored with TMS
    T Baumer
    Neurology Department, Hamburg University, Martinistrasse 52, D 20246 Hamburg, Germany
    Suppl Clin Neurophysiol 56:160-9. 2003
  18. doi request reprint The cortical motor threshold reflects microstructural properties of cerebral white matter
    Stefan Kloppel
    Department of Neurology, Neurozentrum, University Clinic Freiburg, Freiburg, Germany
    Neuroimage 40:1782-91. 2008
    ....
  19. doi request reprint Deep brain stimulation of the ventrolateral thalamic base and posterior subthalamic area in dystonic head tremor
    Carsten Buhmann
    Department of Neurology, University Medical Center Hamburg Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany
    Acta Neurochir Suppl 117:67-72. 2013
    ..Chronic stimulation improved not only head tremor but also CD. These findings suggest that DBS at the base of VL thalamus and the adjacent PSA should undergo further investigation as a potential target for patients with DHT...
  20. doi request reprint The human dorsal premotor cortex facilitates the excitability of ipsilateral primary motor cortex via a short latency cortico-cortical route
    Sergiu Groppa
    Department of Neurology, Christian Albrechts University, Kiel, Germany
    Hum Brain Mapp 33:419-30. 2012
    ..This paradigm opens up new possibilities to study context-dependent intrahemispheric PMd-to-M1(HAND) interactions in the intact human brain...
  21. doi request reprint Right hemisphere contributions to imitation tasks
    Katja Biermann-Ruben
    Department of Neurology, MEG Laboratory, Dusseldorf University Hospital, Moorenstrasse 5, 40225 Duesseldorf, Germany
    Eur J Neurosci 27:1843-55. 2008
    ....
  22. ncbi request reprint Prefrontal cortex volume reductions and tic inhibition are unrelated in uncomplicated GTS adults
    Christos Ganos
    Department of Neurology, University Medical Center Hamburg Eppendorf UKE, Hamburg, Germany Sobell Department of Motor Neuroscience and Movement Disorders, University College London Institute of Neurology, London, United Kingdom Department of Paediatric and Adult Movement Disorders and Neuropsychiatry, Institute of Neurogenetics, University of Lubeck, Germany Electronic address
    J Psychosom Res 76:84-7. 2014
    ..The relation between prefrontal cortex structure and tic inhibition has not been investigated...
  23. doi request reprint Brain iron deposition fingerprints in Parkinson's disease and progressive supranuclear palsy
    Kai Boelmans
    Department of Neurology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Mov Disord 27:421-7. 2012
    ..Regional decreases of T2' relaxation times in parts of the basal ganglia reflecting increased brain iron load in these areas are characteristic for progressive supranuclear palsy but not PD patients...
  24. doi request reprint Clinical neuroimaging and electrophysiological assessment of three DYT6 dystonia families
    Simone Zittel
    Department of Neurology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Mov Disord 25:2405-12. 2010
    ..SN hyperechogenicity on TCS may represent an endophenotype in these patients. Pallidal DBS in two patients was unsatisfactory...
  25. ncbi request reprint Abnormal plasticity of the sensorimotor cortex to slow repetitive transcranial magnetic stimulation in patients with writer's cramp
    Tobias Bäumer
    Department of Neurology, University of Hamburg, Hamburg, Germany
    Mov Disord 22:81-90. 2007
    ....
  26. ncbi request reprint Motor cortex excitability after thalamic infarction
    J Liepert
    Department of Neurology, University Hospital Eppendorf, Martinistr 52, D 20246 Hamburg, Germany
    Clin Neurophysiol 116:1621-7. 2005
    ..We examined 8 patients with hemihypesthesia due to an ischemic thalamic lesion to explore the effects of a central sensory dysfunction on motor cortex excitability...
  27. doi request reprint The functional anatomy of Gilles de la Tourette syndrome
    Christos Ganos
    Department of Neurology, University Medical Centre Hamburg Eppendorf UKE, Hamburg 20246, Germany
    Neurosci Biobehav Rev 37:1050-62. 2013
    ....
  28. doi request reprint Transcranial magnetic stimulation studies of sensorimotor networks in Tourette syndrome
    Michael Orth
    Department of Neurology, University of Ulm, Ulm, Germany
    Behav Neurol 27:57-64. 2013
    ..In GTS the gain of many motor circuits may be reduced and hence less sensitive to small changes in input from other areas. These cortical changes may constitute an adaptive response to abnormal basal ganglia-motor cortex inputs...
  29. pmc Identification and functional analysis of novel THAP1 mutations
    Katja Lohmann
    Section of Clinical and Molecular Neurogenetics, Department of Neurology, University of Lubeck, Lubeck, Germany
    Eur J Hum Genet 20:171-5. 2012
    ..Speech was affected in four mutation carriers. In conclusion, THAP1 mutations are rare in unselected dystonia patients and functional analysis is necessary to distinguish between benign variants and pathogenic mutations...
  30. doi request reprint Arm tremor in cervical dystonia--is it a manifestation of dystonia or essential tremor?
    Sarah Schiebler
    Department of Neurology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Mov Disord 26:1789-92. 2011
    ..From this point of view, we outline this tremor debate and add some new clinical data...
  31. ncbi request reprint Clinical and neurophysiological profile of four german families with spinocerebellar ataxia type 14
    Christos Ganos
    Department of Neurology, University Medical Centre Hamburg Eppendorf, Hamburg, Germany
    Cerebellum 13:89-96. 2014
    ..Other neurophysiological parameters did not differ between groups. SCA14 is a slowly progressive ataxia associated with mild dystonia and myoclonus. Reduced SICI reflects abnormalities of intracortical inhibitory circuits. ..
  32. ncbi request reprint Are premonitory urges a prerequisite of tic inhibition in Gilles de la Tourette syndrome?
    Christos Ganos
    Movement Disorders Research Group, Department of Neurology, University Medical Centre Hamburg Eppendorf, Martinistr 52, 20246 Hamburg, Germany
    J Neurol Neurosurg Psychiatry 83:975-8. 2012
    ..We examined the relation of the trait of premonitory urges with tics and tic suppression. We hypothesised that patients with more urges would be more efficient at inhibiting tics...
  33. doi request reprint Corticospinal system excitability at rest is associated with tic severity in tourette syndrome
    Michael Orth
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, London, United Kingdom
    Biol Psychiatry 64:248-51. 2008
    ..However, it is not clear whether these represent abnormalities of specific pathways or reflect a more widespread reduction of motor cortex excitability. Their significance for the clinical phenotype is also unknown...
  34. ncbi request reprint Observation of a finger or an object movement primes imitative responses differentially
    M Jonas
    Department of Neurology, University Medical Center Hamburg Eppendorf, Martinistr 52, 20246, Hamburg, Germany
    Exp Brain Res 177:255-65. 2007
    ..Thus, S1 immediately elicits an imitative response tendency. As an overt imitation of S1 is inadequate in the present setting, the response is inhibited which, in turn, modulates congruency effects...
  35. pmc Mirtazapine increases cortical excitability in healthy controls and epilepsy patients with major depression
    A Munchau
    Sobell Department of Motor Neuroscience and Movement Disorders, Dept of Clinical and Experimental Epilepsy, Institute of Neurology, National Hospital for Neurology and Neurosurgery, Queen Square, London, UK
    J Neurol Neurosurg Psychiatry 76:527-33. 2005
    ..Epilepsy is often complicated by depression requiring antidepressant treatment. Such treatment might be proconvulsive...
  36. ncbi request reprint Do simple intransitive finger movements consistently activate frontoparietal mirror neuron areas in humans?
    M Jonas
    NeuroImage Nord, Hamburg Kiel Lübeck, Germany
    Neuroimage 36:T44-53. 2007
    ..We propose that the responsiveness of human frontoparietal mirror neuron areas to simple intransitive movements critically depends on the experimental context...
  37. ncbi request reprint Interhemispheric effects of high and low frequency rTMS in healthy humans
    A Gorsler
    Department of Neurology, University Hospital Hamburg Eppendorf, Hamburg, Germany
    Clin Neurophysiol 114:1800-7. 2003
    ..We investigated whether repetitive transcranial magnetic stimulation (rTMS) applied to the right motor cortex modified the excitability of the unstimulated left motor cortex...
  38. ncbi request reprint Motor excitability in a patient with a somatosensory cortex lesion
    Joachim Liepert
    Department of Neurology, University of Hamburg, University Hospital Eppendorf, Martinistrasse 52, D 20246, Hamburg, Germany
    Clin Neurophysiol 114:1003-8. 2003
    ..We report a patient with an ischemic lesion in right somatosensory cortex who developed dystonic posturing and pseudo-athetotic involuntary left-sided finger movements during voluntary muscle contractions...
  39. doi request reprint Sensory afferent inhibition within and between limbs in humans
    R Bikmullina
    Department of Neurology, University Medical Centre Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
    Clin Neurophysiol 120:610-8. 2009
    ..To examine the distribution and inter-limb interaction of short-latency afferent inhibition (SAI) in the arm and leg...
  40. ncbi request reprint Modulation of motor cortex excitability induced by pinch grip repetition
    A Gorsler
    Department of Neurology, University Hospital, Hamburg Eppendorf, Germany
    J Neural Transm 111:1005-16. 2004
    ..In another experiment, these stimulations were performed before and after a 30-minute right handed pinch grip training...
  41. pmc Altered synaptic plasticity in Tourette's syndrome and its relationship to motor skill learning
    Valerie Cathérine Brandt
    Institute of Neurogenetics, University of Lubeck, Lubeck, Schleswig Holstein, Germany Department of Neurology, University Clinic Hamburg Eppendorf, Hamburg, Hamburg, Germany
    PLoS ONE 9:e98417. 2014
    ..Moreover, synaptic plasticity appears to be related to symptom severity. ..
  42. doi request reprint Hirayama disease is a pure spinal motor neuron disorder--a combined DTI and transcranial magnetic stimulation study
    Kai Boelmans
    Department of Psychiatry, Memory Clinic, University Hospital Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
    J Neurol 260:540-8. 2013
    ..CMCT was normal in HirD patients. Combined anatomical and functional measurements established normal integrity of the supraspinal CST in HirD patients lending support to the notion that HirD is a pure spinal motor neuron disorder...
  43. doi request reprint The pathophysiology of echopraxia/echolalia: relevance to Gilles de la Tourette syndrome
    Christos Ganos
    Department of Neurology, University Medical Center Hamburg Eppendorf UKE, Hamburg, Germany
    Mov Disord 27:1222-9. 2012
    ..The neural basis of echophenomena will also be addressed. © 2012 Movement Disorder Society...
  44. ncbi request reprint Autosomal dominant myoclonus-dystonia and Tourette syndrome in a family without linkage to the SGCE gene
    Michael Orth
    Department of Neurology, University Medical Centre Hamburg Eppendorf, Hamburg, Germany
    Mov Disord 22:2090-6. 2007
    ..The SGCE and the SLITRK1 gene were sequenced and investigated by gene dosage analysis in selected family members. Linkage to the SGCE, DYT15, DYT1, DRD2, and SLITRK1 loci was also tested...
  45. doi request reprint Cost of illness in patients with Gilles de la Tourette's syndrome
    Ines Dodel
    Department of Neurology, Philipps University Marburg, Rudolf Bultmann Str 8, Marburg, Germany
    J Neurol 257:1055-61. 2010
    ..Unfortunately, no cost of illness studies are available for comparison. Further health economic studies, especially cost-effectiveness studies, are necessary for a basis for rational resource allocation...
  46. ncbi request reprint Subthreshold 5-Hz repetitive transcranial magnetic stimulation of the human primary motor cortex reduces intracortical paired-pulse inhibition
    A Peinemann
    Department of Neurology, Technische Universitat Munchen, D 81675, Munich, Germany
    Neurosci Lett 296:21-4. 2000
    ..The lasting effect of subthreshold 5-Hz rTMS on intracortical inhibition provides a useful probe for studying short-term plasticity of the human M1(HAND)...
  47. doi request reprint Altered modulation of intracortical excitability during movement preparation in Gilles de la Tourette syndrome
    K F Heise
    Department of Neurology, University Medical Center Hamburg Eppendorf, 20246 Hamburg, Germany
    Brain 133:580-90. 2010
    ....
  48. ncbi request reprint Right temporoparietal gray matter predicts accuracy of social perception in the autism spectrum
    Nicole David
    Department of Neurophysiology and Pathophysiology, University Medical Center Hamburg Eppendorf, Martinistr 52, 20246, Hamburg, Germany
    J Autism Dev Disord 44:1433-46. 2014
    ..Our findings suggest that social-perceptual difficulties in ASD cannot be reduced to deficits in spatial-temporal integration. ..
  49. ncbi request reprint Life-threatening respiratory failure due to cranial dystonia after dental procedure in a patient with multiple system atrophy
    Farsin Hamzei
    Neurology Department, Hamburg University, Hamburg, Germany
    Mov Disord 18:959-61. 2003
    ..Dystonia spread rapidly to involve other facial muscles and the larynx causing stridor with respiratory failure necessitating crush intubation...
  50. ncbi request reprint ATP13A2 mutations impair mitochondrial function in fibroblasts from patients with Kufor-Rakeb syndrome
    Anne Grünewald
    Section of Clinical and Molecular Neurogenetics, Department of Neurology, University of Lubeck, Lubeck, Germany
    Neurobiol Aging 33:1843.e1-7. 2012
    ..These findings collectively suggest that ATP13A2 contributes to the maintenance of a healthy mitochondrial pool, supporting the hypothesis that impaired mitochondrial clearance represents an important pathogenic mechanism underlying KRS...
  51. ncbi request reprint How to assess motor impairment in writer's cramp
    Kirsten E Zeuner
    Department of Neurology, Christian Albrechts University Kiel, Kiel, Germany
    Mov Disord 22:1102-9. 2007
    ..Future studies need to address which combination of clinical scores and kinematic measures are most appropriate to quantify impairment in writer's cramp...
  52. doi request reprint Subthalamotomy in cervical dystonia: A case study of lesion location and clinical outcome
    Christian K E Moll
    Department of Neurophysiology and Pathophysiology, Center of Experimental Medicine, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Mov Disord 23:1751-6. 2008
    ....
  53. ncbi request reprint Abnormal excitability of premotor-motor connections in de novo Parkinson's disease
    C Buhmann
    Department of Neurology, University of Hamburg, Hamburg, Germany
    Brain 127:2732-46. 2004
    ....
  54. doi request reprint Psychogenic paroxysmal movement disorders--clinical features and diagnostic clues
    Christos Ganos
    Sobell Department of Motor Neuroscience and Movement Disorders, UCL Institute of Neurology, University College London, Queen Square, London WC1N 3BG, UK Department of Neurology, University Medical Center Hamburg Eppendorf UKE, Hamburg, Germany
    Parkinsonism Relat Disord 20:41-6. 2014
    ..The diagnosis of psychogenic paroxysmal movement disorders (PPMD) can be challenging, in particular their distinction from the primary paroxysmal dyskinesias (PxD) remains difficult...
  55. ncbi request reprint Lesion of the dorsorostral midbrain sparing the nigrostriatal tract mimics axial rigidity seen in progressive supranuclear palsy
    Jan Lewerenz
    Department of Neurology, University of Hamburg, Hamburg, Germany
    Mov Disord 20:1071-5. 2005
    ..We suggest that dorsorostral midbrain pathology rather than dopamine deficiency due to degeneration of nigrostriatal dopaminergic neurons or basal ganglia nuclei might be responsible for axial rigidity in extension...
  56. ncbi request reprint Implementation of visuospatial cues in response selection
    Thilo van Eimeren
    NeuroImage Nord, Department of Neurology, University Medical Center Hamburg Eppendorf, Germany
    Neuroimage 29:286-94. 2006
    ..We propose that the latter set of dorsal parieto-frontal areas subserves rapid implementation of spatial information during visually guided response selection...
  57. ncbi request reprint Image-based classification of parkinsonian syndromes using T2'-atlases
    Nils Daniel Forkert
    Department of Medical Informatics, University Medical Center Hamburg Eppendorf, Germany
    Stud Health Technol Inform 169:465-9. 2011
    ..The evaluation using leave-one-out validation revealed that the proposed method achieves a classification accuracy of 91%. The presented method might serve as the basis for an improved automatic classification of PS in the future...
  58. ncbi request reprint Clinical and genetic features of myoclonus-dystonia in 3 cases: a video presentation
    Norman Kock
    Department of Neurology, University of Schleswig Holstein, Lubeck, Germany
    Mov Disord 19:231-4. 2004
    ..We describe 3 children with a similar clinical picture of autosomal dominant M-D and an SGCE mutation in only one of them, suggesting that M-D is genetically heterogeneous...
  59. ncbi request reprint Sensorimotor integration is abnormal in asymptomatic Parkin mutation carriers: a TMS study
    T Baumer
    Department of Neurology, University of Hamburg, Martinistrasse 52, 20246 Hamburg, Germany
    Neurology 69:1976-81. 2007
    ....