Rory E Morty

Summary

Affiliation: University of Giessen
Country: Germany

Publications

  1. request reprint
    Morty R, Morehead J. Cloning and characterization of a leucyl aminopeptidase from three pathogenic Leishmania species. J Biol Chem. 2002;277:26057-65 pubmed
    ..Lap was not secreted by Leishmania in vitro and was localized to the parasite cytosol. ..
  2. Morty R, Bulau P, Pelle R, Wilk S, Abe K. Pyroglutamyl peptidase type I from Trypanosoma brucei: a new virulence factor from African trypanosomes that de-blocks regulatory peptides in the plasma of infected hosts. Biochem J. 2006;394:635-45 pubmed
    ..The abnormal degradation of TRH and GnRH, and perhaps other neuropeptides N-terminally blocked with a pyroglutamyl moiety, by trypanosome PGP, may contribute to some of the endocrine lesions observed in African trypanosomiasis. ..
  3. request reprint
    Morty R, Nejman B, Kwapiszewska G, Hecker M, Zakrzewicz A, Kouri F, et al. Dysregulated bone morphogenetic protein signaling in monocrotaline-induced pulmonary arterial hypertension. Arterioscler Thromb Vasc Biol. 2007;27:1072-8 pubmed
    ..BMP signaling and BMP-regulated physiological phenomena are perturbed in MCT-treated rats, lending solid support to the proposed roles for BMP signaling in the pathogenesis of human PAH. ..
  4. Morty R, Eickelberg O, Seeger W. Alveolar fluid clearance in acute lung injury: what have we learned from animal models and clinical studies?. Intensive Care Med. 2007;33:1229-1240 pubmed publisher
    ..The failure of patients to resolve the alveolar edema associated with these conditions is a major contributing factor to mortality; hence there is continued interest to understand the mechanisms of alveolar edema fluid clearance...
  5. Surate Solaligue D, Rodríguez Castillo J, Ahlbrecht K, Morty R. Recent advances in our understanding of the mechanisms of late lung development and bronchopulmonary dysplasia. Am J Physiol Lung Cell Mol Physiol. 2017;:ajplung.00343.2017 pubmed publisher
    ....
  6. Morty R. Accepting the challenge: maintaining AJP-Lung as the best place to publish basic and translational studies in lung biology and pathophysiology. Am J Physiol Lung Cell Mol Physiol. 2017;:ajplung.00488.2017 pubmed publisher
    ....

Locale

Detail Information

Publications6

  1. request reprint
    Morty R, Morehead J. Cloning and characterization of a leucyl aminopeptidase from three pathogenic Leishmania species. J Biol Chem. 2002;277:26057-65 pubmed
    ..Lap was not secreted by Leishmania in vitro and was localized to the parasite cytosol. ..
  2. Morty R, Bulau P, Pelle R, Wilk S, Abe K. Pyroglutamyl peptidase type I from Trypanosoma brucei: a new virulence factor from African trypanosomes that de-blocks regulatory peptides in the plasma of infected hosts. Biochem J. 2006;394:635-45 pubmed
    ..The abnormal degradation of TRH and GnRH, and perhaps other neuropeptides N-terminally blocked with a pyroglutamyl moiety, by trypanosome PGP, may contribute to some of the endocrine lesions observed in African trypanosomiasis. ..
  3. request reprint
    Morty R, Nejman B, Kwapiszewska G, Hecker M, Zakrzewicz A, Kouri F, et al. Dysregulated bone morphogenetic protein signaling in monocrotaline-induced pulmonary arterial hypertension. Arterioscler Thromb Vasc Biol. 2007;27:1072-8 pubmed
    ..BMP signaling and BMP-regulated physiological phenomena are perturbed in MCT-treated rats, lending solid support to the proposed roles for BMP signaling in the pathogenesis of human PAH. ..
  4. Morty R, Eickelberg O, Seeger W. Alveolar fluid clearance in acute lung injury: what have we learned from animal models and clinical studies?. Intensive Care Med. 2007;33:1229-1240 pubmed publisher
    ..The failure of patients to resolve the alveolar edema associated with these conditions is a major contributing factor to mortality; hence there is continued interest to understand the mechanisms of alveolar edema fluid clearance...
  5. Surate Solaligue D, Rodríguez Castillo J, Ahlbrecht K, Morty R. Recent advances in our understanding of the mechanisms of late lung development and bronchopulmonary dysplasia. Am J Physiol Lung Cell Mol Physiol. 2017;:ajplung.00343.2017 pubmed publisher
    ....
  6. Morty R. Accepting the challenge: maintaining AJP-Lung as the best place to publish basic and translational studies in lung biology and pathophysiology. Am J Physiol Lung Cell Mol Physiol. 2017;:ajplung.00488.2017 pubmed publisher
    ....