Affiliation: University of Regensburg
Morsczeck C, Völlner F, Saugspier M, Brandl C, Reichert T, Driemel O, et al
. Comparison of human dental follicle cells (DFCs) and stem cells from human exfoliated deciduous teeth (SHED) after neural differentiation in vitro. Clin Oral Investig. 2010;14:433-40 pubmed publisher
..In conclusion, SHED and DFCs have different neural differentiation potentials under the same cell culture conditions. ..
Morsczeck C. Cellular senescence in dental pulp stem cells. Arch Oral Biol. 2019;99:150-155 pubmed publisher
..However, there is no cell culture protocol available that prevents dental stem cell senescence. Therefore, more knowledge about molecular processes in stem cells is needed before and after the induction of senescence. ..
Morsczeck C, Reck A, Reichert T. WNT5A supports viability of senescent human dental follicle cells. Mol Cell Biochem. 2019;455:21-28 pubmed publisher
..However, an inhibition of WNT5A did only slightly effect the osteogenic differentiation of DFCs. Our results suggest that WNT5A supports viability during both cell proliferation and osteogenic differentiation of DFCs. ..
Morsczeck C, Reichert T, Völlner F, Gerlach T, Driemel O. [The state of the art in human dental stem cell research]. Mund Kiefer Gesichtschir. 2007;11:259-66 pubmed
..Nonetheless dental stem cells are CD45 negative and they express rarely hematopoietic stem cell markers. These research results plead for the participation of dental stem cells in dental practice in future. ..
Morsczeck C, Frerich B, Driemel O. Dental stem cell patents. Recent Pat DNA Gene Seq. 2009;3:39-43 pubmed
..This following review summarizes patents about dental stem cells for dental tissue engineering and considers their value for regenerative dentistry. ..
Morsczeck C, Schmalz G, Reichert T, Völlner F, Galler K, Driemel O. Somatic stem cells for regenerative dentistry. Clin Oral Investig. 2008;12:113-8 pubmed publisher
..These cells are easily accessible and, in contrast to bone-marrow-derived mesenchymal stem cells, are more closely related to dental tissues. This review gives a short overview of stem cells of dental origin. ..
Morsczeck C, Schmalz G, Reichert T, Völlner F, Saugspier M, Viale Bouroncle S, et al
. Gene expression profiles of dental follicle cells before and after osteogenic differentiation in vitro. Clin Oral Investig. 2009;13:383-91 pubmed publisher
..In conclusion, we present the first transcriptome of human DFCs before and after osteogenic differentiation. This study sheds new light on the complex mechanism of osteogenic differentiation in DFCs. ..
Morsczeck C, Ernst W, Florian C, Reichert T, Proff P, Bauer R, et al
. Gene expression of nestin, collagen type I and type III in human dental follicle cells after cultivation in serum-free medium. Oral Maxillofac Surg. 2008;12:89-92 pubmed publisher
..In the age of bovine spongiform encephalopathy (BSE), a serum-free cell culture system for dental follicle cells are recommended, if these cells will be applied in dentistry...
Morsczeck C, Schmalz G. Transcriptomes and proteomes of dental follicle cells. J Dent Res. 2010;89:445-56 pubmed publisher
..This review describes the transcriptomes and proteomes of dental follicle cells before and after differentiation, and compares them with differentially expressed populations from dental tissue or bone marrow...