Hans Jurgen Moller

Summary

Affiliation: University of Munich
Country: Germany

Publications

  1. doi request reprint A case of persistent retrograde amnesia following a dissociative fugue: neuropsychological and neurofunctional underpinnings of loss of autobiographical memory and self-awareness
    Kristina Hennig-Fast
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Nussbaumstr 7, Munich, Germany
    Neuropsychologia 46:2993-3005. 2008
  2. ncbi request reprint Bipolar disorder and schizophrenia: distinct illnesses or a continuum?
    Hans Jurgen Moller
    Psychiatric Department of the University of Munich, Munich, Germany
    J Clin Psychiatry 64:23-7; discussion 28. 2003
  3. ncbi request reprint The bipolar spectrum: diagnostic and pharmacologic considerations
    Hans Jurgen Moller
    Psychiatric Department, University of Munich, Nussbaumstr 7, D 80336 Munich, Germany
    Expert Rev Neurother 4:S3-8. 2004
  4. ncbi request reprint Amisulpride: efficacy in the management of chronic patients with predominant negative symptoms of schizophrenia
    H J Moller
    Department of Psychiatry, University of Munich, Germany
    Eur Arch Psychiatry Clin Neurosci 251:217-24. 2001
  5. ncbi request reprint Methodological aspects in the assessment of severity of depression by the Hamilton Depression Scale
    H J Moller
    Department of Psychiatry Ludwig Maximilians University, Munich, Germany
    Eur Arch Psychiatry Clin Neurosci 251:II13-20. 2001
  6. ncbi request reprint Definition, psychopharmacological basis and clinical evaluation of novel/atypical neuroleptics: methodological issues and clinical consequences
    H J Moller
    Psychiatric Hospital, Ludwig Maximilian University, Munich, Germany
    World J Biol Psychiatry 1:75-91. 2000
  7. ncbi request reprint State of the art of drug treatment of schizophrenia and the future position of the novel/atypical antipsychotics
    H J Moller
    Department of Psychiatry, Ludwig Maximilians University, Nussbaumstr 7, 80336 Munich, Germany
    World J Biol Psychiatry 1:204-14. 2000
  8. ncbi request reprint Treatment of bipolar disorder
    Hans Jurgen Moller
    Psychiatric Department of University Munich, Munich, Germany
    J Clin Psychiatry 64:9-17; discussion 28. 2003
  9. ncbi request reprint Anxiety associated with comorbid depression
    Hans Jurgen Moller
    Department of Psychiatry, Psychiatrische Universitatsklinik, Munich, Germany
    J Clin Psychiatry 63:22-6. 2002
  10. ncbi request reprint Management of the negative symptoms of schizophrenia: new treatment options
    Hans Jurgen Moller
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    CNS Drugs 17:793-823. 2003

Collaborators

Detail Information

Publications137 found, 100 shown here

  1. doi request reprint A case of persistent retrograde amnesia following a dissociative fugue: neuropsychological and neurofunctional underpinnings of loss of autobiographical memory and self-awareness
    Kristina Hennig-Fast
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Nussbaumstr 7, Munich, Germany
    Neuropsychologia 46:2993-3005. 2008
    ..It is posited that our data provide evidence for the important role of visual processing in autobiographical memory as well as for the efficiency of protective control mechanisms that constitute functional retrograde amnesia...
  2. ncbi request reprint Bipolar disorder and schizophrenia: distinct illnesses or a continuum?
    Hans Jurgen Moller
    Psychiatric Department of the University of Munich, Munich, Germany
    J Clin Psychiatry 64:23-7; discussion 28. 2003
    ..Ongoing research should aid in the understanding of bipolar disorder and foster the development of more effective treatment...
  3. ncbi request reprint The bipolar spectrum: diagnostic and pharmacologic considerations
    Hans Jurgen Moller
    Psychiatric Department, University of Munich, Nussbaumstr 7, D 80336 Munich, Germany
    Expert Rev Neurother 4:S3-8. 2004
    ....
  4. ncbi request reprint Amisulpride: efficacy in the management of chronic patients with predominant negative symptoms of schizophrenia
    H J Moller
    Department of Psychiatry, University of Munich, Germany
    Eur Arch Psychiatry Clin Neurosci 251:217-24. 2001
    ..Amisulpride was well tolerated with a safety profile similar to placebo. These results open a new therapeutic approach for negative symptoms, one of the most disabling aspects of schizophrenia...
  5. ncbi request reprint Methodological aspects in the assessment of severity of depression by the Hamilton Depression Scale
    H J Moller
    Department of Psychiatry Ludwig Maximilians University, Munich, Germany
    Eur Arch Psychiatry Clin Neurosci 251:II13-20. 2001
    ..This is demonstrated by the evaluation of two sertraline-amitriptyline comparative studies...
  6. ncbi request reprint Definition, psychopharmacological basis and clinical evaluation of novel/atypical neuroleptics: methodological issues and clinical consequences
    H J Moller
    Psychiatric Hospital, Ludwig Maximilian University, Munich, Germany
    World J Biol Psychiatry 1:75-91. 2000
    ..It also describes differences in the unwanted adverse events profile of the different new/atypical antipsychotics...
  7. ncbi request reprint State of the art of drug treatment of schizophrenia and the future position of the novel/atypical antipsychotics
    H J Moller
    Department of Psychiatry, Ludwig Maximilians University, Nussbaumstr 7, 80336 Munich, Germany
    World J Biol Psychiatry 1:204-14. 2000
    ..As was the situation with the classical neuroleptics, the physician also has to choose the most adequate drug under consideration of the risk/benefit profile of each drug in relation to the disposition of the individual patient...
  8. ncbi request reprint Treatment of bipolar disorder
    Hans Jurgen Moller
    Psychiatric Department of University Munich, Munich, Germany
    J Clin Psychiatry 64:9-17; discussion 28. 2003
    ..This article provides an overview of current management strategies for patients with bipolar disorder and describes how these approaches can be incorporated into clinical practice...
  9. ncbi request reprint Anxiety associated with comorbid depression
    Hans Jurgen Moller
    Department of Psychiatry, Psychiatrische Universitatsklinik, Munich, Germany
    J Clin Psychiatry 63:22-6. 2002
    ..It also compares efficacy data from trials of benzodiazepines used alone and in combination with antidepressants for the treatment of anxiety disorders comorbid with depression...
  10. ncbi request reprint Management of the negative symptoms of schizophrenia: new treatment options
    Hans Jurgen Moller
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    CNS Drugs 17:793-823. 2003
    ..Other traditionally suggested approaches, such as comedication with an antiepileptic drug, lithium or beta-adrenoceptor antagonist, cannot generally be recommended on the basis of the available data...
  11. ncbi request reprint [Antistigma and awareness program: saying no to the discrimination of the mentally ill]
    H J Moller
    Klinik und Poliklinik fur Psychiatrie und Psychotherapie, Klinikum der Universitat Munchen
    MMW Fortschr Med 145:33. 2003
  12. ncbi request reprint Amisulpride: limbic specificity and the mechanism of antipsychotic atypicality
    Hans Jurgen Moller
    Department of Psychiatry, Ludwig Maximilians University, Nussbaumstrasse 7, 80336 Munich, Germany
    Prog Neuropsychopharmacol Biol Psychiatry 27:1101-11. 2003
    ..In addition, the fast dissociation hypothesis can contribute to the explanation of the atypical clinical profile of amisulpride. The relevance of the D3 blockade in the context of atypicality is not yet completely clear...
  13. ncbi request reprint [49. Phobic disorder, panic or generalized anxiety? Basic principles in diagnosis and therapy]
    H J Moller
    Psychiatrische Klinik, Ludwig Maximilians Universitat Munchen
    MMW Fortschr Med 145:I-VIII; quiz IX-X. 2003
  14. ncbi request reprint Associations of SNAP-25 polymorphisms with cognitive dysfunctions in Caucasian patients with schizophrenia during a brief trail of treatment with atypical antipsychotics
    Ilja Spellmann
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University of Munich, Nussbaumstrasse 7, 80336, Munich, Germany
    Eur Arch Psychiatry Clin Neurosci 258:335-44. 2008
    ....
  15. ncbi request reprint Reduced hippocampal volumes associated with the long variant of the serotonin transporter polymorphism in major depression
    Thomas Frodl
    Department of Psychiatry, Ludwig Maximilians University of Munich, Munich, Germany
    Arch Gen Psychiatry 61:177-83. 2004
    ..Several studies have found reciprocal interactions between the serotonergic system and both brain-derived neurotrophic factor and glutamate, which are known to modulate or affect hippocampal morphologic characteristics...
  16. doi request reprint Depression during an acute episode of schizophrenia or schizophreniform disorder and its impact on treatment response
    Markus Jager
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Psychiatry Res 158:297-305. 2008
    ..Therefore, the hypothesis that depressive symptoms are predictive of a favorable treatment response was not supported by the present study...
  17. doi request reprint Remission and recovery and their predictors in schizophrenia spectrum disorder: results from a 1-year follow-up naturalistic trial
    Rebecca Schennach
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University Munich, Nussbaumstrasse 7, 80336, Munich, Germany
    Psychiatr Q 83:187-207. 2012
    ..0113) were found to be significantly predictive of recovery. Our results underline the need to implement more specific treatment strategies to improve long-term outcome...
  18. doi request reprint Predictors of relapse in the year after hospital discharge among patients with schizophrenia
    Rebecca Schennach
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Nussbaumstreet 7, 80336 Munich, Germany
    Psychiatr Serv 63:87-90. 2012
    ..Relapse and its predictors were examined among patients with schizophrenia in the year after hospital discharge...
  19. doi request reprint Homer-1 polymorphisms are associated with psychopathology and response to treatment in schizophrenic patients
    Ilja Spellmann
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University of Munich, Nußbaumstrasse 7, 80336 Munich, Germany
    J Psychiatr Res 45:234-41. 2011
    ..Thus, these data might further help in detecting differential therapy response in individuals with schizophrenia...
  20. doi request reprint Functional connectivity bias of the orbitofrontal cortex in drug-free patients with major depression
    Thomas Frodl
    Department of Psychiatry and Psychotherapy, Ludwig Maximilian University, Munich, Germany
    Biol Psychiatry 67:161-7. 2010
    ..The aim of this study was to compare the functional connectivity of the OFC during emotion processing in patients with major depression and healthy control subjects...
  21. doi request reprint Quality of life and subjective well-being in schizophrenia and schizophrenia spectrum disorders: valid predictors of symptomatic response and remission?
    Rebecca Schennach-Wolff
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
    World J Biol Psychiatry 11:729-38. 2010
    ..To examine quality of life and subjective well-being as predictors of symptomatic treatment outcome...
  22. ncbi request reprint Association of the brain-derived neurotrophic factor Val66Met polymorphism with reduced hippocampal volumes in major depression
    Thomas Frodl
    Department of Psychiatry and Psychotherapy and Radiology, Ludwig Maximilians University, Munich, Germany
    Arch Gen Psychiatry 64:410-6. 2007
    ..Brain-derived neurotrophic factor (BDNF) modulates hippocampal plasticity, which is believed to be altered in patients with major depression...
  23. ncbi request reprint Elevated brain serotonin transporter availability in patients with obsessive-compulsive disorder
    Oliver Pogarell
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Biol Psychiatry 54:1406-13. 2003
    ..The aim of this study was to investigate the serotonin transporter availability in patients with OCD as an in vivo marker of the central serotonergic system...
  24. ncbi request reprint The influence of concomitant neuroleptic medication on safety, tolerability and clinical effectiveness of electroconvulsive therapy
    Caroline Nothdurfter
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
    World J Biol Psychiatry 7:162-70. 2006
    ..In these cases, concomitant pharmacotherapy can be a useful augmentation strategy to improve clinical effectiveness. Interestingly, there is not much data about ECT and concomitant neuroleptic medication...
  25. ncbi request reprint Striatal dopamine release after prefrontal repetitive transcranial magnetic stimulation in major depression: preliminary results of a dynamic [123I] IBZM SPECT study
    Oliver Pogarell
    Department of Psychiatry, Ludwig Maximilians University, Nussbaumstr 7, D 80336 Munich, Germany
    J Psychiatr Res 40:307-14. 2006
    ..In future, this approach can be used to differentiate specific and non-specific reward-related effects of rTMS on dopaminergic neurotransmission...
  26. doi request reprint Depressive symptoms and their association with acute treatment outcome in first-episode schizophrenia patients: comparing treatment with risperidone and haloperidol
    Michael Riedel
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
    World J Biol Psychiatry 13:30-8. 2012
    ..To evaluate depressive symptoms regarding their association with the acute outcome in first-episode schizophrenia comparing risperidone and haloperidol...
  27. ncbi request reprint Altered brain activation during a verbal working memory task in subjects with amnestic mild cognitive impairment
    Arun L W Bokde
    Department of Psychiatry and Psychotherapy, Ludwig Maximilian University, Alzheimer Memorial Center, Munich, Germany
    J Alzheimers Dis 21:103-18. 2010
    ..The activation differences between groups may be compensatory mechanisms within the MCI group for the effects of the putative AD neuropathology. This has been the first study that has examined verbal working memory in MCI...
  28. ncbi request reprint Does early improvement in major depression protect against treatment emergent suicidal ideation?
    Florian Seemüller
    Department of Psychiatry, Ludwig Maximilians University, Nussbaumstr 7, Munich, Germany
    J Affect Disord 124:183-6. 2010
    ..To investigate the association of early improvement and treatment emergent suicidal ideation in a large sample (N=705) of naturalistically treated inpatients with major depressive disorder...
  29. ncbi request reprint Anterior cingulum volumetry, auditory P300 in schizophrenia with negative symptoms
    Ulrich W Preuss
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Nussbaumstrasse 7, D 80336 Munich, Germany
    Psychiatry Res 183:133-9. 2010
    ..In addition, while right hemisphere ACC volumes significantly differ between schizophrenia subgroups, combining measures of event-related potential (ERP) and ACC volumetry does not add additional information...
  30. ncbi request reprint The dysbindin gene in major depression: an association study
    Peter Zill
    Psychiatric Hospital of the Ludwig Maximilians University, Munich, Germany
    Am J Med Genet B Neuropsychiatr Genet 129:55-8. 2004
    ..Further analysis are needed to confirm these results...
  31. ncbi request reprint Amygdala volume and depressive symptoms in patients with borderline personality disorder
    Thomas Zetzsche
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
    Biol Psychiatry 60:302-10. 2006
    ..The aim of this study was to examine whether a co-occurrence of MD is associated with structural changes in the amygdala of BPD patients...
  32. doi request reprint Multivariate patterns of brain-cognition associations relating to vulnerability and clinical outcome in the at-risk mental states for psychosis
    Nikolaos Koutsouleris
    Department of Psychiatry and Psychotherapy, Ludwig Maximilian University, Munich, Germany
    Hum Brain Mapp 33:2104-24. 2012
    ..However, structure-cognition relationships in the ARMS have not been directly explored using multivariate neuroimaging techniques...
  33. doi request reprint Differences in hippocampal volume between major depression and schizophrenia: a comparative neuroimaging study
    Eva M Meisenzahl
    Department of Psychiatry and Psychotherapy, Ludwig Maximilian University, Nussbaumstrasse 7, Munich, Germany
    Eur Arch Psychiatry Clin Neurosci 260:127-37. 2010
    ....
  34. ncbi request reprint Effects of risperidone and quetiapine on cognition in patients with schizophrenia and predominantly negative symptoms
    Michael Riedel
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University of Munich, Nussbaumstrasse 7, 80336, Munich, Germany
    Eur Arch Psychiatry Clin Neurosci 257:360-70. 2007
    ..Also, the improvements in cognition following treatment with quetiapine and risperidone may enhance long-term outcomes for these patients...
  35. ncbi request reprint Association analysis of a polymorphism in the G-protein stimulatory alpha subunit in patients with major depression
    Peter Zill
    Psychiatric Hospital of the Ludwig Maximilians University, Munich, Germany
    Am J Med Genet 114:530-2. 2002
    ....
  36. ncbi request reprint Prediction of symptom remission in schizophrenia during inpatient treatment
    Markus Jager
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    World J Biol Psychiatry 10:426-34. 2009
    ..The present study applied the symptom-severity component of these criteria to a sample of inpatients in order to determine the rates of remission during inpatient treatment and to explore predictors of remission...
  37. doi request reprint Neuroanatomical correlates of executive dysfunction in the at-risk mental state for psychosis
    Nikolaos Koutsouleris
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
    Schizophr Res 123:160-74. 2010
    ....
  38. doi request reprint Use of neuroanatomical pattern regression to predict the structural brain dynamics of vulnerability and transition to psychosis
    Nikolaos Koutsouleris
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
    Schizophr Res 123:175-87. 2010
    ..To date, it is unknown whether these dynamic brain changes can be predicted at the single-subject level prior to disease transition using MRI-based machine-learning techniques...
  39. pmc Reduced hippocampal volume correlates with executive dysfunctioning in major depression
    Thomas Frodl
    Department of Psychiatry, Ludwig Maximilians University of Munich, Munich, Germany
    J Psychiatry Neurosci 31:316-23. 2006
    ..We aimed to investigate whether reduced hippocampal volumes correlate with executive dysfunctioning or memory dysfunctioning or with depression severity...
  40. ncbi request reprint Tachykinin receptor 1 variants associated with aggression in suicidal behavior
    Ina Giegling
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Am J Med Genet B Neuropsychiatr Genet 144:757-61. 2007
    ..In conclusion, our study suggests that TACR1 gene variants have no major influence on suicidal behavior but may modulate aggression features...
  41. ncbi request reprint Estrogen receptor gene 1 variants are not associated with suicidal behavior
    Ina Giegling
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Psychiatry Res 160:1-7. 2008
    ..In conclusion, our study does not support the hypothesis that estrogen receptor alpha gene variants are major contributors to suicide or to anger- or aggression-related behaviors...
  42. ncbi request reprint Kinematical analysis of motor function in schizophrenic patients: a possibility to separate negative symptoms from extrapyramidal dysfunction induced by neuroleptics?
    Verena Henkel
    Department of Psychiatry, Ludwig Maximilians University Munich, Munich, Germany
    Pharmacopsychiatry 37:110-8. 2004
    ..In this prospective matched case-control study, hand movement analysis was conducted using a digitizing tablet (kinematical analysis)...
  43. ncbi request reprint A functional single nucleotide polymorphism (V158M) in the COMT gene is associated with aggressive personality traits
    Dan Rujescu
    Department of Psychiatry, Division of Molecular Neurobiology, Ludwig Maximilians University, Munich, Germany
    Biol Psychiatry 54:34-9. 2003
    ..Catechol-O-methyltransferase (COMT) is an enzyme involved in catecholamine inactivation. In this study, we examined the influence of a functional COMT (V158M) polymorphism on suicidal behavior and anger-related traits...
  44. ncbi request reprint Depression with atypical features in a sample of primary care outpatients: prevalence, specific characteristics and consequences
    Verena Henkel
    Department of Psychiatry, Ludwig Maximilians University Munich, Nussbaumstr 7, D 80336 Munich, Germany
    J Affect Disord 83:237-42. 2004
    ....
  45. ncbi request reprint Correlation of cerebrospinal fluid levels of tau protein phosphorylated at threonine 231 with rates of hippocampal atrophy in Alzheimer disease
    Harald Hampel
    Alzheimer Memorial Center and Geriatric Psychiatry Branch, Dementia and Neuroimaging Section, Department of Psychiatry, Ludwig Maximilian University, Munich, Germany
    Arch Neurol 62:770-3. 2005
    ..We hypothesized that these variations partially reflect differences in the degree of neuronal damage and therefore may be used to predict structural disease progression...
  46. ncbi request reprint Anger- and aggression-related traits are associated with polymorphisms in the 5-HT-2A gene
    Ina Giegling
    Molecular and Clinical Neurobiology, Department of Psychiatry, University of Munich, Germany
    J Affect Disord 96:75-81. 2006
    ....
  47. doi request reprint Influence of ANKK1 and DRD2 polymorphisms in response to haloperidol
    Ina Giegling
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Eur Arch Psychiatry Clin Neurosci 263:65-74. 2013
    ..Our findings support a possible role of ANKK1 and DRD2 variability on haloperidol efficacy. However, due to the discrepancies between the results in the two samples, our results need further validation...
  48. doi request reprint Response trajectories in "real-world" naturalistically treated schizophrenia patients
    Rebecca Schennach
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
    Schizophr Res 139:218-24. 2012
    ..To date, research has identified distinct antipsychotic response trajectories yet focussing on data from randomized-controlled trials (RCTs). Therefore, the heterogeneity of response in "real-world" schizophrenia patients is still unknown...
  49. ncbi request reprint Celecoxib treatment in an early stage of schizophrenia: results of a randomized, double-blind, placebo-controlled trial of celecoxib augmentation of amisulpride treatment
    Norbert Muller
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians Universitat Munchen, Germany
    Schizophr Res 121:118-24. 2010
    ..In future, further trials are needed to investigate the effect of COX-2 inhibitors on prodromal and negative symptoms of schizophrenia...
  50. ncbi request reprint Use of brief depression screening tools in primary care: consideration of heterogeneity in performance in different patient groups
    Verena Henkel
    Department of Psychiatry, Ludwig Maximilians University Munich, Nussbaumstr 7, D 80336 Munich, Germany
    Gen Hosp Psychiatry 26:190-8. 2004
    ..This should be considered if routine depression screening should be widely introduced. Of course, the benefit of routine screening also depends on efforts made for treatment and monitoring of patients in whom depression was diagnosed...
  51. ncbi request reprint Auditory cortex and anterior cingulate cortex sources of the early evoked gamma-band response: relationship to task difficulty and mental effort
    Christoph Mulert
    Department of Psychiatry, LMU, Nussbaumstrasse 7, D 80336 Munich, Germany
    Neuropsychologia 45:2294-306. 2007
    ..These findings are in line with a top-down influence of dACC-activity to the auditory association area 22 during the early evoked GBR...
  52. ncbi request reprint Inefficient neural activity in patients with schizophrenia and nonpsychotic relatives of schizophrenic patients: evidence from a working memory task
    Susanne Karch
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Nussbaumstrasse 7, D 80336 Munich, Germany
    J Psychiatr Res 43:1185-94. 2009
    ..In addition, compensatory strategies were demonstrated. These findings suggest that the genetic risk for schizophrenia is accompanied by neural inefficiency which is associated with cognitive deficits, especially in difficult tasks...
  53. doi request reprint Reduced early auditory evoked gamma-band response in patients with schizophrenia
    Gregor Leicht
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, 7D 80336 Munich, Germany
    Biol Psychiatry 67:224-31. 2010
    ..power and phase-locking in schizophrenic patients?; and 2) Is this possible decrease a result of reduced activity in the auditory cortex and/or the anterior cingulate cortex (ACC), which were identified as sources of the GBR previously?..
  54. ncbi request reprint Clinical predictors of response and remission in inpatients with depressive syndromes
    Michael Riedel
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University Munich, Nussbaumstrasse 7, 80336 Munich, Germany
    J Affect Disord 133:137-49. 2011
    ..We aimed at detecting a set of clinical baseline variables for prediction of response and remission in 1014 naturalistically treated inpatients with major depressive episode treated for 53.62 ± 47.5 days...
  55. ncbi request reprint Beneficial antipsychotic effects of celecoxib add-on therapy compared to risperidone alone in schizophrenia
    Norbert Muller
    Psychiatric and Psychotherapeutic Hospital, Ludwig Maximilians University, Munich, Germany
    Am J Psychiatry 159:1029-34. 2002
    ..The authors conducted a trial of the new selective cyclooxygenase-2 inhibitor celecoxib, an immunomodulatory drug, in schizophrenic patients to evaluate its therapeutic effects...
  56. ncbi request reprint Beta-1-adrenergic receptor gene in major depression: influence on antidepressant treatment response
    Peter Zill
    Psychiatric Hospital of the Ludwig Maximilians University, Munich, Germany
    Am J Med Genet B Neuropsychiatr Genet 120:85-9. 2003
    ..05). However, after correction for multiple testing (Bonferroni) these results did not remain significant. Nevertheless, these findings suggest that the presence of the C allele might be an indicator for antidepressant treatment response...
  57. ncbi request reprint Differential diagnosis of Alzheimer disease with cerebrospinal fluid levels of tau protein phosphorylated at threonine 231
    Katharina Buerger
    Dementia Research Section and Memory Clinic, Alzheimer Memorial Center, Geriatric Psychiatry Branch, Department of Psychiatry, Ludwig Maximilian University, Nussbaumstrasse 7, 80336 Munich, Germany
    Arch Neurol 59:1267-72. 2002
    ....
  58. doi request reprint Attention to emotion: auditory-evoked potentials in an emotional choice reaction task and personality traits as assessed by the NEO FFI
    Verena Mittermeier
    Department of Psychiatry and Psychotherapy, LMU, Munich, Germany
    Eur Arch Psychiatry Clin Neurosci 261:111-20. 2011
    ..Interestingly, subjects with high scores in the personality trait extraversion showed significantly higher EPN amplitudes for emotional paradigms (syllables and words) than introverted subjects...
  59. ncbi request reprint Dopa decarboxylase and tyrosine hydroxylase gene variants in suicidal behavior
    Ina Giegling
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Am J Med Genet B Neuropsychiatr Genet 147:308-15. 2008
    ..In conclusion, our study does not support the involvement of TH gene variants as major contributors to suicide, whereas DDC variants could mediate some features related to suicide and be involved in violent suicidal behavior...
  60. ncbi request reprint Hippocampal and amygdala changes in patients with major depressive disorder and healthy controls during a 1-year follow-up
    Thomas Frodl
    Department of Psychiatry, Clinical Center Innenstadt, Ludwig Maximilians University, Nussbaumstrasse 7, 80336 Munich, Germany
    J Clin Psychiatry 65:492-9. 2004
    ....
  61. ncbi request reprint Serotonergic dysfunction in schizophrenia assessed by the loudness dependence measure of primary auditory cortex evoked activity
    Georg Juckel
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Schizophr Res 64:115-24. 2003
    ..These results suggest that the loudness dependence of primary auditory cortex evoked activity is well suitable to assess serotonergic dysfunction in schizophrenia...
  62. pmc Early recognition and disease prediction in the at-risk mental states for psychosis using neurocognitive pattern classification
    Nikolaos Koutsouleris
    Department of Psychiatry and Psychotherapy, Ludwig Maximilian University, Nussbaumstrasse 7, 80336 Munich, Germany
    Schizophr Bull 38:1200-15. 2012
    ....
  63. ncbi request reprint Akathisia and suicidal ideation in first-episode schizophrenia
    Florian Seemüller
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
    J Clin Psychopharmacol 32:694-8. 2012
    ..The allocated treatment, anxiety, and nervousness had no influence. The present findings suggest a promoting effect of akathisia on suicidal ideation can not be ruled out in patients with FES...
  64. doi request reprint Influencing factors and predictors of early improvement in the acute treatment of schizophrenia and schizophrenia spectrum disorder
    Rebecca Schennach-Wolff
    Department of Psychiatry, Ludwig Maximilians University, Nussbaumstr 7, 80336 Munich, Germany
    J Psychiatr Res 45:1639-47. 2011
    ..To examine the influencing factors and predictors of early improvement in schizophrenia patients...
  65. ncbi request reprint A Ser9Gly polymorphism in the dopamine D3 receptor gene (DRD3) and event-related P300 potentials
    Christoph Mulert
    Department of Psychiatry, University of Munich, LMU, Munich, Germany
    Neuropsychopharmacology 31:1335-44. 2006
    ..Further studies should address the direct role of the DRD3 Ser9Gly polymorphism in attenuated P300 amplitudes in psychiatric disorders like schizophrenia or alcoholism...
  66. ncbi request reprint A pharmacological model for psychosis based on N-methyl-D-aspartate receptor hypofunction: molecular, cellular, functional and behavioral abnormalities
    Dan Rujescu
    Division of Molecular and Clinical Neurobiology, Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Biol Psychiatry 59:721-9. 2006
    ....
  67. pmc Psychopathological characteristics and treatment response of first episode compared with multiple episode schizophrenic disorders
    Markus Jager
    Department of Psychiatry, Ludwig Maximilians University, Nussbaumstr 7, D 80336 Munich, Germany
    Eur Arch Psychiatry Clin Neurosci 257:47-53. 2007
    ..The aim was to investigate the hypothesis that patients with first episode schizophrenic disorders have a more favorable treatment response than those with multiple episodes...
  68. ncbi request reprint NOS-I and -III gene variants are differentially associated with facets of suicidal behavior and aggression-related traits
    Dan Rujescu
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Am J Med Genet B Neuropsychiatr Genet 147:42-8. 2008
    ..0002; sliding haplotype T-G, P = 0.002). In conclusion, our study suggests a possible involvement of NOS-I and NOS-III gene variants in suicidal behavior and related intermediate phenotypes...
  69. ncbi request reprint Efficacy of olanzapine versus quetiapine on cognitive dysfunctions in patients with an acute episode of schizophrenia
    Michael Riedel
    Dept of Psychiatry and Psychotherapy, Ludwig Maximilians University of Munich, Nussbaumstrasse 7, 80336 Munich, Germany
    Eur Arch Psychiatry Clin Neurosci 257:402-12. 2007
    ..Furthermore, quetiapine produced a significantly greater improvement in reaction quality/attention than olanzapine...
  70. doi request reprint Short-term treatment with risperidone or haloperidol in first-episode schizophrenia: 8-week results of a randomized controlled trial within the German Research Network on Schizophrenia
    Hans Jurgen Moller
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
    Int J Neuropsychopharmacol 11:985-97. 2008
    ..Risperidone has better extrapyramidal tolerability and treatment retention rate than the equivalent dose of haloperidol in these patients...
  71. ncbi request reprint World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for biological treatment of bipolar disorders. Part I: Treatment of bipolar depression
    Heinz Grunze
    Department of Psychiatry, Ludwig Maximilians University, Nussbaumstrasse 7, 80336 Munich, Germany
    World J Biol Psychiatry 3:115-24. 2002
    ..As these guidelines are intended for clinical use, the scientific evidence was not only graded, but also commented on by the experts of the task force to ensure practicability...
  72. ncbi request reprint Differentiation of geriatric major depression from Alzheimer's disease with CSF tau protein phosphorylated at threonine 231
    Katharina Buerger
    Dementia Research Section and Memory Clinic, Alzheimer Memorial Center and Geriatric Psychiatry Branch, Department of Psychiatry, Ludwig Maximilian University, Munich, Germany
    Am J Psychiatry 160:376-9. 2003
    ..The authors asked whether p-tau(231) levels improve the differential diagnosis between geriatric major depression and Alzheimer's disease...
  73. ncbi request reprint Sound level dependence of the primary auditory cortex: Simultaneous measurement with 61-channel EEG and fMRI
    Christoph Mulert
    Department of Psychiatry, LMU, Munich, Germany
    Neuroimage 28:49-58. 2005
    ..In addition, the correspondence of the ERP-based data and the fMRI results further supports the validity of the ERP localization approach...
  74. ncbi request reprint The Munich 15-year follow-up study (MUFUSSAD) on first-hospitalized patients with schizophrenic or affective disorders: comparison of psychopathological and psychosocial course and outcome and prediction of chronicity
    Hans Jurgen Moller
    Department of Psychiatry, University of Munich, Nussbaumstrasse 7, 80336, Munich, Germany
    Eur Arch Psychiatry Clin Neurosci 260:367-84. 2010
    ..The Strauss-Carpenter Scale, male gender as well as several psychopathological syndromes are the most relevant predictors for chronicity...
  75. doi request reprint Influence of neuronal cell adhesion molecule (NCAM1) variants on suicidal behaviour and correlated traits
    Ina Giegling
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Psychiatry Res 179:222-5. 2010
    ..However, independent studies are needed to validate these results...
  76. ncbi request reprint Negative symptoms in depressed and schizophrenic patients: how do they differ?
    Ronald Bottlender
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    J Clin Psychiatry 64:954-8. 2003
    ..nonenduring) can help to improve their specificity for schizophrenia...
  77. ncbi request reprint On the descriptive validity of ICD-10 schizophrenia: empirical analyses in the spectrum of non-affective functional psychoses
    Markus Jager
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Psychopathology 36:152-9. 2003
    ..The results are in line with a high descriptive validity of ICD-10 schizophrenia and highlight the importance of negative symptoms for this diagnosis...
  78. ncbi request reprint Does clinical judgment of baseline severity and changes in psychopathology depend on the patient population? Results of a CGI and PANSS linking analysis in a naturalistic study
    Rebecca Schennach-Wolff
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University Munich, Munich, Germany
    J Clin Psychopharmacol 30:726-31. 2010
    ..Furthermore, these linking results were compared with those derived from randomized controlled trials to examine if the baseline severity might influence the linking results...
  79. doi request reprint Predictors of response and remission in the acute treatment of first-episode schizophrenia patients--is it all about early response?
    Rebecca Schennach-Wolff
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
    Eur Neuropsychopharmacol 21:370-8. 2011
    ..To evaluate the predictive validity of early response compared to other well-known predictor variables in acutely ill first-episode patients...
  80. doi request reprint Neurocognition and its influencing factors in the treatment of schizophrenia-effects of aripiprazole, olanzapine, quetiapine and risperidone
    M Riedel
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University Munich, Munich, Germany
    Hum Psychopharmacol 25:116-25. 2010
    ..To examine influencing variables of neurocognition in patients with schizophrenia and to predict cognition during antipsychotic treatment...
  81. doi request reprint Early improvement as a predictor of remission and response in schizophrenia: Results from a naturalistic study
    M Jager
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Eur Psychiatry 24:501-6. 2009
    ..To examine the predictive validity of early improvement in a naturalistic sample of inpatients and to identify the criterion that best defines early improvement...
  82. doi request reprint Is the polarity of relapse/recurrence in bipolar-I disorder patients related to serum lithium levels? Results from an empirical study
    W E Severus
    Department of Psychiatry, University of Munich, Munich, Germany
    J Affect Disord 115:466-70. 2009
    ..Preliminary evidence suggests that the polarity of relapse/recurrence (depressive vs. hypomanic/manic/mixed) in bipolar patients on lithium might be related to serum lithium levels...
  83. ncbi request reprint Cerebral network deficits in post-acute catatonic schizophrenic patients measured by fMRI
    J Scheuerecker
    Department of Psychiatry, Ludwig Maximilians University, Nussbaumstrasse 7, 80336 Munich, Germany
    J Psychiatr Res 43:607-14. 2009
    ..Our findings are in agreement with earlier behavioral data, which show deficits in self-initiated movements in catatonic patients but no impairment of externally triggered movements...
  84. ncbi request reprint Association of short-term response to haloperidol treatment with a polymorphism in the dopamine D(2) receptor gene
    M Schafer
    Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Am J Psychiatry 158:802-4. 2001
    ..Pharmacogenetic influences on therapeutic response to neuroleptic treatment are poorly understood. This study investigates the association of response to short-term haloperidol treatment with a Taq I polymorphism in the DRD2 gene...
  85. ncbi request reprint Loudness dependence of primary auditory-cortex-evoked activity as predictor of therapeutic outcome to prophylactic lithium treatment in affective disorders--a retrospective study
    G Juckel
    Section of Clinical Neurophysiology, Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Pharmacopsychiatry 37:46-51. 2004
    ....
  86. doi request reprint Effect of aripiprazole on cognition in the treatment of patients with schizophrenia
    M Riedel
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
    Pharmacopsychiatry 43:50-7. 2010
    ..The aim of this study was to assess the cognitive effects of aripiprazole in inpatients with schizophrenia...
  87. doi request reprint Time course of antipsychotic treatment response in schizophrenia: results from a naturalistic study in 280 patients
    M Jager
    Department of Psychiatry, Ludwig Maximilians University, Nussbaumstr 7, D 80336 Munich, Germany
    Schizophr Res 118:183-8. 2010
    ..To describe the course of positive and negative symptoms during inpatient treatment and examine remission and response rates under routine clinical care conditions...
  88. ncbi request reprint Enlarged cerebrospinal fluid spaces in opiate-dependent male patients: a stereological CT study
    P Danos
    Department of Psychiatry, University of Magdeburg, Germany
    Neuropsychobiology 38:80-3. 1998
    ..The present results suggest that opiate dependence is associated with structural brain alterations. However, the relationship between opiate dependence and structural brain changes is complex and still not well understood...
  89. doi request reprint [Core symptoms of depression. Effectiveness of antidepressant therapy]
    J Damm
    Klinik fur Psychiatrie und Psychotherapie, Ludwig Maximilians Universitat, Nussbaumstrasse 7, 80336, Munchen
    Nervenarzt 80:515-6, 518, 520 passim. 2009
    ..Because the positive diagnosis of the core symptoms of depression may include clinical consequences, it would be useful to integrate all these concepts into the upcoming new versions of the diagnostic systems DSM-V and ICD-11...
  90. doi request reprint Postmortem proteomic analysis in human amygdala of drug addicts: possible impact of tubulin on drug-abusing behavior
    P Zill
    Department of Psychiatry, Division of Psychiatric Genetics and Neurochemistry, Ludwig Maximilians University Munich, Nussbaumstrasse 7, 80336 Munich, Germany
    Eur Arch Psychiatry Clin Neurosci 261:121-31. 2011
    ..Although further studies have to confirm our results, this might be a possible pathway that may increase our understanding of drug addiction...
  91. ncbi request reprint Are antidepressants less effective in the acute treatment of bipolar I compared to unipolar depression?
    H J Moller
    Department of Psychiatry of the Ludwig Maximilians University, Nussbaumstrasse 7, 80336 Munich, Germany
    J Affect Disord 67:141-6. 2001
    ..Using our routine documentation system we evaluated the hypothesis that antidepressants may be less effective in the acute treatment of bipolar I depressed patients compared to unipolar depressed patients...
  92. doi request reprint A critical analysis and discussion of the appropriateness of the schizophrenia consensus remission criteria in clinical pharmaceutical trials
    R Schennach-Wolff
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
    Pharmacopsychiatry 43:245-51. 2010
    ..The aim of this paper is to apply the proposed consensus remission criteria to an acutely ill inpatient sample at admission and evaluate their adaptability in this patient population and pharmaceutical trials...
  93. doi request reprint A pilot study of the safety and efficacy of amisulpride and risperidone in elderly psychotic patients
    M Riedel
    Department of Psychiatry, Ludwig Maximilians University, Nussbaumstrasse 7, D 80336 Munich, Germany
    Eur Psychiatry 24:149-53. 2009
    ....
  94. doi request reprint Single-trial coupling of the gamma-band response and the corresponding BOLD signal
    C Mulert
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich, Germany
    Neuroimage 49:2238-47. 2010
    ..Single-trial coupling might be a useful method in order to increase our knowledge about the functional neuroanatomy of "neural ensembles" coupled by 40 Hz oscillations...
  95. doi request reprint Striatal D2/D3 receptor occupancy, clinical response and side effects with amisulpride: an iodine-123-iodobenzamide SPET study
    E M Meisenzahl
    Department of Psychiatry, LMU University of Munich, Munich, Germany
    Pharmacopsychiatry 41:169-75. 2008
    ..Amisulpride appears to be an effective atypical agent for treating schizophrenia in a dose-dependent manner...
  96. ncbi request reprint Decreased soluble interleukin-6 receptor in cerebrospinal fluid of patients with Alzheimer's disease
    H Hampel
    Department of Psychiatry, Ludwig Maximilian University Munich, School of Medicine, Germany
    Brain Res 780:356-9. 1998
    ..We found a statistically significant decrease in sIL-6R levels in the AD group compared to controls. Complete analysis of the IL-6R complex seems crucial to better understand the impact of IL-6 in AD pathophysiology...
  97. ncbi request reprint Neuroleptic malignant syndrome due to atypical neuroleptics: three episodes in one patient
    R Bottlender
    Department of Psychiatry, Ludwig Maximilians University, Munich
    Pharmacopsychiatry 35:119-21. 2002
    ..The epivodes of NMS occured under treatment with clozapine, risperidone, and amisulpride. These episodes had some atypical features that will be discussed with regard to the pathophysiological mechanisms leading to NMS...
  98. ncbi request reprint In vivo imaging of region and cell type specific neocortical neurodegeneration in Alzheimer's disease. Perspectives of MRI derived corpus callosum measurement for mapping disease progression and effects of therapy. Evidence from studies with MRI, EEG and
    H Hampel
    Department of Psychiatry, Alzheimer Memorial Center and Geriatric Psychiatry Branch, Dementia and Neuroimaging Section, Ludwig Maximilian University, Munich, Federal Republic of Germany
    J Neural Transm 109:837-55. 2002
    ....
  99. ncbi request reprint Are bipolar I depressive patients less responsive to treatment with antidepressants than unipolar depressive patients? Results from a case control study
    R Bottlender
    Department of Psychiatry, Ludwig Maximilians University, Nussbaumstr 7, 80336 Munich, Germany
    Eur Psychiatry 17:200-5. 2002
    ....
  100. ncbi request reprint Association of anger-related traits with SNPs in the TPH gene
    D Rujescu
    Molecular Neurobiology, Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Mol Psychiatry 7:1023-9. 2002
    ..These findings support the hypothesis that the A218C and the A779C SNP in the TPH gene may be associated with anger-related traits in German samples...
  101. ncbi request reprint Kinematic analysis of handwriting movements in patients with Alzheimer's disease, mild cognitive impairment, depression and healthy subjects
    A Schroter
    Department of Psychiatry, Ludwig Maximilian University Munich, Munich, Germany
    Dement Geriatr Cogn Disord 15:132-42. 2003
    ..Both patients with MCI and patients with probable AD exhibited loss of fine motor performance. Movements of AD patients were significantly less regular than those of healthy controls...