Research Topics
| Th W F MittlmeierSummaryAffiliation: University of Rostock Country: Germany Publications
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Detail Information
Publications
Investigation of first ray mobility during gait by kinematic fluoroscopic imaging--a novel methodHeiner Martin
Institute for Biomedical Engineering, University of Rostock, F Barnewitz Str, 4, D 18119 Rostock, Germany
BMC Musculoskelet Disord 13:14. 2012..The aim of this study was to develop a technique which allows for a quantification of the in-vivo sagittal mobility of the joints of the medial foot column during the roll-over process under full weight bearing...
[Articulated external fixator at the elbow]T Mittlmeier
Abteilung für Unfall und Wiederherstellungschirurgie, Chirurgische Klinik und Poliklinik der Universität Rostock, Rostock, Germany
Unfallchirurg 112:506-12. 2009..The articulated external fixator further represents a salvage procedure for delayed reconstructions and distraction arthrolysis, as well. A precise surgical technique is a prerequisite for the success of the procedure...
[Posttraumatic arthritis in the hind foot]T Mittlmeier
Abteilung für Unfall und Wiederherstellungschirurgie, Chirurgische Klinik und Poliklinik der Universität Rostock
Unfallchirurg 109:125-46; quiz 147-8. 2006..In general, an arthrodesis of any hind foot joint, as a key element in hind foot reconstruction, will be successful if correction of the underlying deformity is also adequately addressed...
[Clinical gait analysis]T Mittlmeier
Abt für Unfall und Wiederherstellungschirurgie, Chirurgische Klinik und Poliklinik der Universität Rostock
Unfallchirurg 108:614-29. 2005..Simple procedures of gait analysis may suffice to obtain information on gait function which can not be derived by mere clinical observation and which can be incorporated into a clinical concept...
[Retrograde medullary locking nail in periprosthetic distal femoral fracture after condylar knee joint replacement]T Mittlmeier
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Unfallchirurg 108:497-501. 2005
[Periprosthetic fractures after total knee joint arthroplasty]T Mittlmeier
Abteilung für Unfall und Wiederherstellungschirurgie, Chirurgische Klinik und Poliklinik der Universität Rostock
Unfallchirurg 108:481-95; quiz 496. 2005....
[Charcot foot. Current situation and outlook]T Mittlmeier
Abteilung für Unfall und Wiederherstellungschirurgie, Chirurgische Klinik und Poliklinik der Universität Rostock, Schillingallee 35, 18055, Rostock, Deutschland
Unfallchirurg 111:218-31. 2008..As such, surgical reconstruction can contribute to the long-term preservation of the affected foot and help to maintain or improve the patient's mobility and quality of life...
[How to become a trauma surgeon: analysis of the current situation and concepts for career development in the new common field of orthopaedics and trauma surgery--part II]T Mittlmeier
Abteilung für Unfall und Wiederherstellungschirurgie, Chirurgische Klinik und Poliklinik der Universität Rostock, Schillingallee 35, 18055, Rostock, Deutschland
Unfallchirurg 113:598-605. 2010..Thus a systematic and creative reorganization of the residency and fellowship phases will overcome any problem of attractiveness...
[Dislocation of the adult elbow joint]T Mittlmeier
Abteilung für Unfall und Wiederherstellungschirurgie, Chirurgische Klinik und Poliklinik der Universität Rostock, Rostock, Germany
Unfallchirurg 112:487-505. 2009..A standardized surgical algorithm may provide the basis to achieve a satisfactory functional result in this challenging clinical entity of elbow trauma...
[Tarsometatarsal injuries--an often neglected entity]Th Mittlmeier
Chirurgische Klinik und Poliklinik der Universität Rostock, Abteilung für Unfall und Wiederherstellungschirurgie, Rostock
Ther Umsch 61:459-65. 2004....
Sesamoid and toe fracturesThomas Mittlmeier
Chirurgische Klinik und Poliklinik der Universität Rostock, Abteilung für Unfall und Wiederherstellungschirurgie, Germany
Injury 35:SB87-97. 2004....
Should one consider primary surgical reconstruction in charcot arthropathy of the feet?Thomas Mittlmeier
Chirurgische Klinik und Poliklinik der Universität Rostock, Abteilung für Unfall und Wiederherstellungschirurgie, Schillingallee 35, 18055, Rostock, Germany
Clin Orthop Relat Res 468:1002-11. 2010..Level of Evidence: Level IV, therapeutic study (case series). See Guidelines for Authors for a complete description of levels of evidence...
[Acute compartment syndrome and complex trauma of the foot]T Mittlmeier
Abteilung für Unfall und Wiederherstellungschirurgie, Chirurgischen Klinik und Poliklinik, Schillingallee 35, 18055, Rostock, Deutschland
Unfallchirurg 114:893-900. 2011..An interdisciplinary approach is often deemed to be essential for a reasonable outcome. None of the accepted scores have proven to be useful for primary decision-making of amputation or for the assessment of the long-term prognosis...
[The infected diabetic foot]T Mittlmeier
Abteilung für Unfall und Wiederherstellungschirurgie, Chirurgische Klinik und Poliklinik der Universität Rostock, Schillingallee 35, 18055, Rostock, Deutschland
Unfallchirurg 114:227-35. 2011....
[Injuries of the midfoot]T Mittlmeier
Abt für Unfall und Wiederherstellungschirurgie, Chirurgische Klinik und Poliklinik, Universitat Rostock, Deutschland
Chirurg 82:169-86; quiz 187-8. 2011..The principal strategy of treatment includes anatomical reconstruction of the joint structures, the geometric proportions of the medial, central and lateral foot columns and the diagnostics and treatment of ligamentous instabilities...
[Management of severe soft-tissue trauma in the upper extremity - shoulder, upper and lower arm]Thomas Mittlmeier
Abteilung für Unfall und Wiederherstellungschirurgie, Chirurgische Klinik und Poliklinik, Universitat Rostock
Oper Orthop Traumatol 22:196-211. 2010..Limitation of secondary soft-tissue loss. Prevention of infection...
[How to become a trauma surgeon: analysis of the current situation and concepts for career development in the new common field of orthopaedics and trauma surgery--part I]T Mittlmeier
Abt für Unfall und Wiederherstellungschirurgie, Chirurgische Klinik und Poliklinik der Universität Rostock, Schillingallee 35, 18055, Rostock, Deutschland
Unfallchirurg 113:504-12. 2010....
Stabilization of proximal humeral fractures with an angular and sliding stable antegrade locking nail (Targon PH)Th W F Mittlmeier
Chirugische Klinik und Poliklinik der Universitaet Rostock, , Rostock, Germany
J Bone Joint Surg Am 85:136-46. 2003
Angular and sliding stable antegrade nailing (Targon PH) for the treatment of proximal humeral fracturesGeorg Gradl
Department of Trauma and Reconstructive Surgery, University of Rostock, Schillingallee 35, 18055, Rostock, Germany
Arch Orthop Trauma Surg 127:937-44. 2007..The purpose of this study was to evaluate the functional outcome and the complication rate of an angular and sliding stable antegrade interlocking nail for the treatment of displaced proximal humeral fractures...
Benefit and accuracy of intraoperative 3D-imaging after pedicle screw placement: a prospective study in stabilizing thoracolumbar fracturesMarkus Beck
Department of Trauma and Reconstructive Surgery, University of Rostock, Schillingallee 35, 18057, Rostock, Germany
Eur Spine J 18:1469-77. 2009..But intraoperative evaluation of the 3D scans resulted in a primary revision rate of 2.7% of the pedicle screws and we could lower the secondary revision rate to 0.5%...
Introduction of a new interlocked intramedullary nailing device for stabilization of critically sized femoral defects in the rat: A combined biomechanical and animal experimental studyMatthias Schoen
Institute for Experimental Surgery, University of Rostock, 18055 Rostock, Germany
J Orthop Res 26:184-9. 2008..Nevertheless, our data corroborate the necessity of an internal fixation device with sufficient axial and rotational stability...
Microcirculatory sequelae of the rotator cuff after antegrade nailing in proximal humerus fracturePhilip Gierer
Department of Trauma and Reconstructive Surgery, University of Rostock, Schillingallee 35, 18057, Rostock, Germany
Arch Orthop Trauma Surg 130:687-91. 2010..Since the surgical procedure in antegrade humeral nailing requires a split of the supraspinatus tendon, the question arises whether the surgical approach causes microcirculatory dysfunction of the tendon...
Intraoperative three-dimensional fluoroscopy assessment of iliosacral screws and lumbopelvic implants stabilizing fractures of the os sacrumMarkus Beck
Department of Trauma and Reconstructive Surgery, University of Rostock, Germany
Arch Orthop Trauma Surg 130:1363-9. 2010..The current standard to control the screw position is postoperative computed tomography. The study presents the results of assessment of these implants by intraoperative three-dimensional fluoroscopy...
[Fixation of distal radial fractures with the Targon DR nail]Georg Gradl
Abteilung für Unfall und Wiederherstellungschirurgie, Chirurgische Klinik und Poliklinik der Universität Rostock, Rostock, Germany
Oper Orthop Traumatol 21:472-83. 2009..Anatomic restoration and intramedullary fixation of distal radial fractures using a hybrid between plate and nail (Targon DR). The technique provides a less invasive operative approach from radial...
Intraoperative position determination of bone cement trocars by 3-dimensional imaging in patients with osteoporotic vertebral fracturesMarkus Beck
Department of Trauma and Reconstructive Surgery, University of Rostock, Rostock, Germany
J Spinal Disord Tech 23:e16-23. 2010..A prospective diagnostic study to evaluate the use of intraoperative 3-dimensional (3D) imaging...
Partial weight bearing after surgery for fractures of the lower extremity--is it achievable?Attila Vasarhelyi
Abteilung für Unfall und Wiederherstellungschirurgie Klinik und Poliklinik für Chirurgie, Universitat Rostock, Schillingallee 35, 18055 Rostock, Germany
Gait Posture 23:99-105. 2006..006 and 0.037). This study implies that the conventional concept of postoperative partial weight bearing starting from 200 N and a stepwise increase of the load level until full weight bearing is not valid during clinical practice...
Fractures of the distal radius treated with a nonbridging external fixation technique using multiplanar k-wiresGeorg Gradl
Chirurgische Klinik und Poliklinik der Universität Rostock, Rostock, Germany
J Hand Surg Am 30:960-8. 2005..A method of nonbridging hybrid fixation of distal radius fractures facilitates fracture reduction and allows for free wrist movement...
Sublethal trauma model with systemic endotoxemia for the study of microcirculatory disorders after the second hitPhilip Gierer
Institute for Experimental Surgery, University of Rostock, Rostock, Germany
J Surg Res 147:68-74. 2008..We present an experimental animal model combining initial standardized soft tissue trauma to the left hindlimb of rats with subsequent sublethal systemic endotoxemia...
Efficiency of small-volume resuscitation in restoration of disturbed skeletal muscle microcirculation after soft-tissue trauma and haemorrhagic shockPhilip Gierer
Department of Trauma and Reconstructive Surgery, University of Rostock, Schillingallee 35, 18057 Rostock, Germany
Langenbecks Arch Surg 389:40-5. 2004..Herein, we report on the efficiency of small-volume resuscitation to improve compromised perfusion of traumatised skeletal muscle tissue in shock...
Effect of systemic hypothermia on local soft tissue trauma-induced microcirculatory and cellular dysfunction in miceThomas Knappe
Department of Experimental Surgery, University of Rostock, Rostock, Germany
Crit Care Med 33:1805-13. 2005..These experimental results clearly support clinical efforts to prevent hypothermia in the acutely traumatized patient...
Biomechanical in vitro testing of human osteoporotic lumbar vertebrae following prophylactic kyphoplasty with different candidate materialsRobert Rotter
Department of Trauma and Reconstructive Surgery, University of Rostock, Rostock, Germany
Spine (Phila Pa 1976) 32:1400-5. 2007..Biomechanical study of human osteoporotic lumbar vertebrae following prophylactic kyphoplasty...
Ebselen reduces inflammation and microvascular perfusion failure after blunt skeletal muscle injury of the ratPhilip Gierer
Institute of Experimental Surgery, Department of Trauma and Reconstructive Surgery, University of Rostock, Rostock, Germany
J Trauma 68:853-8. 2010....
Ischemic preconditioning prevents skeletal muscle tissue injury, but not nerve lesion upon tourniquet-induced ischemiaMatthias Schoen
Institute for Experimental Surgery, Department of Trauma and Reconstructive Surgery, University of Rostock, Rostock, Germany
J Trauma 63:788-97. 2007..We demonstrate that tourniquet hind limb ischemia-induced injury of the muscle benefits from IPC, whereas the peripheral nerve suffers from prolonged ischemia time and mechanical deterioration on IPC...
In vivo evidence for apoptosis, but not inflammation in the hindlimb muscle of neuropathic ratsGeorg Gradl
Department of Trauma and Reconstructive Surgery, University of Rostock, Rostock, Germany
Pain 112:121-30. 2004..e. prompting muscle cells to undergo non-inflammatory apoptotic cell death. This finding deserves further investigation in that apoptosis may contribute to neuropathic pain conditions like CRPS...
Gene expression profile and synovial microcirculation at early stages of collagen-induced arthritisPhilip Gierer
Department of Experimental Surgery, University of Rostock, Rostock, Germany
Arthritis Res Ther 7:R868-76. 2005..Online in vivo data on synovial tissue microcirculation, together with gene expression profiling, emphasize the potential role played by early inflammatory events in the development of arthritis...
Selective cyclooxygenase-2 inhibition reverses microcirculatory and inflammatory sequelae of closed soft-tissue trauma in an animal modelPhilip Gierer
Departments of Experimental Surgery, University of Rostock, Schillingallee 70, 18055 Rostock, Germany
J Bone Joint Surg Am 87:153-60. 2005..These results deserve further investigation to prove that selective COX-2 inhibitors improve performance and promote healing following closed soft-tissue injury...
Biomechanical comparison of four anterior atlantoaxial plate systemsFrank Kandziora
Unfall und Wiederherstellungschirurgie, Universitätsklinikum Charité der Humboldt Universität Berlin, Germany
J Neurosurg 96:313-20. 2002..Therefore, three new anterior atlantoaxial plate designs were developed. The purpose of this study was to compare these three newly designed plate systems biomechanically with that used in Harms anterior atlantoaxial plate fixation...
Immediate microcirculatory derangements in skeletal muscle and periosteum after closed tibial fractureLi Zhang
Department of Trauma and Reconstructive Surgery, , Humboldt-University, Berlin, Germany
J Trauma 54:979-85. 2003..It provides a useful approach for the development of therapeutic strategies to counteract fracture-induced microvascular dysfunction...
Acute effects of N-acetylcysteine on skeletal muscle microcirculation following closed soft tissue trauma in ratsKlaus D Schaser
Department of Trauma and Reconstructive Surgery, Charite, Campus Virchow Klinikum, Humboldt Universitat zu Berlin, Augustenburger Platz 1, 13353 Berlin, Germany
J Orthop Res 23:231-41. 2005..Additional studies aimed at long-term analysis and investigation of injury severity--or dosage dependency are needed...
Influence of cage design on interbody fusion in a sheep cervical spine modelFrank Kandziora
Unfall and Wiederherstellungschirurgie, Universitätsklinikum Charité der Humboldt Universität Berlin, Germany
J Neurosurg 96:321-32. 2002....
The logic and clinical applications of blocking screwsHans-Werner Stedtfeld
Department of Trauma, , Germany
J Bone Joint Surg Am 86:17-25. 2004
Exaggeration of tissue trauma induces signs and symptoms of acute CRPS I, however displays distinct differences to experimental CRPS IIGeorg Gradl
Department of Trauma and Reconstructive Surgery, University of Rostock, Germany
Neurosci Lett 402:267-72. 2006..Pain perception displays differences to that in CRPS II. Apoptosis turns out to be a distinctive marker for CRPS, warranting further evaluation in clinical studies...
Prolonged superficial local cryotherapy attenuates microcirculatory impairment, regional inflammation, and muscle necrosis after closed soft tissue injury in ratsKlaus Dieter Schaser
Center of Musculoskeletal Surgery, Charite University Medicine Berlin, Germany
Am J Sports Med 35:93-102. 2007..While superficial cooling reduces swelling, pain, and cellular oxygen demand, the effects of cryotherapy on posttraumatic microcirculation are incompletely understood...
Supernatant of traumatized muscle induces inflammation and pain, but not microcirculatory perfusion failure and apoptotic cell deathGeorg Gradl
Department of Experimental Surgery, University of Rostock, 18055 Rostock, Germany
Shock 24:219-25. 2005..This finding may prompt future efforts in the therapy of closed soft tissue trauma to focus not only on antimediator strategies, but to add regimens targeting perfusion failure and tissue apoptosis...
Activated protein C reduces tissue hypoxia, inflammation, and apoptosis in traumatized skeletal muscle during endotoxemiaPhilip Gierer
Institute for Experimental Surgery, University of Rostock, Germany
Crit Care Med 35:1966-71. 2007..Activated protein C, a natural coagulatory inhibitor, was recently shown to reduce mortality in septic patients. We herein report on the actions of activated protein C on skeletal muscle injury in experimental endotoxemia...
Granulocyte-colony stimulating factor enhances muscle proliferation and strength following skeletal muscle injury in ratsIoannis Stratos
Inst for Experimental Surgery, Univ of Rostock, Schillingallee 69a, 18055 Rostock, Germany
J Appl Physiol 103:1857-63. 2007..Thus G-CSF might represent a therapeutic option to optimize the posttraumatic course of muscle tissue healing...
Bone morphogenetic protein-2 application by a poly(D,L-lactide)-coated interbody cage: in vivo results of a new carrier for growth factorsFrank Kandziora
Unfall und Wiederherstellungschirurgie, Universitätsklinikum Charité der Humboldt Universität Berlin, Germany
J Neurosurg 97:40-8. 2002....
IGF-I and TGF-beta1 application by a poly-(D,L-lactide)-coated cage promotes intervertebral bone matrix formation in the sheep cervical spineFrank Kandziora
Unfall und Wiederherstellungschirurgie, , , Klinikum, Berlin, Germany
Spine 27:1710-23. 2002..Additional longer-term studies are required to determine whether combined IGF-I and TGF-beta1 application leads to a successful spinal fusion...
Atlantoaxial instability in Dyggve-Melchior-Clausen syndrome. Case report and review of the literatureFrank Kandziora
Unfall und Wiederherstellungschirurgie, and Institut für Humangenetik, Universitätsklinikum Charité der Humboldt Universität Berlin, Germany
J Neurosurg 96:112-7. 2002..Specific care must be taken to determine the course of the VA. If posterior and transoral fusion are impossible, anterior transarticular atlantoaxial screw fixation might be the only alternative...
Intra-articular pressure measurement in the radioulnocarpal joint using a novel sensor: in vitro and in vivo resultsDaniel A Rikli
Surgical Department, Kantonsspital Lucerne, Lucerne, Switzerland
J Hand Surg Am 32:67-75. 2007..We performed an in vitro validation of a specifically developed capacitive pressure-sensor device and an in vivo measurement of force transmission and pressure distribution at the radioulnocarpal joint in a healthy volunteer...
