Sarah Minner

Summary

Affiliation: University of Hamburg
Country: Germany

Publications

  1. ncbi request reprint [Tumors of the urinary system. Current and old problems]
    S Minner
    Institut fur Pathologie, Universitatsklinikum Hamburg Eppendorf, Martinistr 52, 20246, Hamburg, Germany
    Pathologe 30:179-84. 2009
  2. doi request reprint Marked heterogeneity of ERG expression in large primary prostate cancers
    Sarah Minner
    Institute of Pathology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Mod Pathol 26:106-16. 2013
  3. ncbi request reprint High level of Ets-related gene expression has high specificity for prostate cancer: a tissue microarray study of 11 483 cancers
    Sarah Minner
    Institute of Pathology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Histopathology 61:445-53. 2012
  4. doi request reprint Epidermal growth factor receptor protein expression and genomic alterations in renal cell carcinoma
    Sarah Minner
    Institute of Pathology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Cancer 118:1268-75. 2012
  5. doi request reprint Y chromosome loss is a frequent early event in urothelial bladder cancer
    Sarah Minner
    Institute of Pathology, University Medical Center Hamburg Eppendorf, Germany
    Pathology 42:356-9. 2010
  6. doi request reprint ERG status is unrelated to PSA recurrence in radically operated prostate cancer in the absence of antihormonal therapy
    Sarah Minner
    Institute of Pathology and Departments of Clinical Chemistry, Bone Marrow Transplantation with Section, Pneumology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Clin Cancer Res 17:5878-88. 2011
  7. doi request reprint Recurrent deletion of 3p13 targets multiple tumour suppressor genes and defines a distinct subgroup of aggressive ERG fusion-positive prostate cancers
    Antje Krohn
    Institute of Pathology, University Medical Centre Hamburg Eppendorf, Hamburg, Germany
    J Pathol 231:130-41. 2013
  8. pmc High mitochondria content is associated with prostate cancer disease progression
    Katharina Grupp
    Institute of Pathology, University Medical Center Hamburg Eppendorf, Martinistr, 52, 20246 Hamburg, Germany
    Mol Cancer 12:145. 2013
  9. ncbi request reprint MALDI imaging on tissue microarrays identifies molecular features associated with renal cell cancer phenotype
    Stefan Steurer
    Institute of Clinical Chemistry, University Medical Center Hamburg Eppendorf, Bldg N27, Room 00 008, Martinistr 52, 20246 Hamburg, Germany
    Anticancer Res 34:2255-61. 2014
  10. ncbi request reprint Prognostic value of alpha-methyl CoA racemase (AMACR) expression in renal cell carcinoma
    Christian Eichelberg
    Department of Urology, University Medical Center Hamburg Eppendorf, Martinistr 52, 20246, Hamburg, Germany
    World J Urol 31:847-53. 2013

Collaborators

Detail Information

Publications53

  1. ncbi request reprint [Tumors of the urinary system. Current and old problems]
    S Minner
    Institut fur Pathologie, Universitatsklinikum Hamburg Eppendorf, Martinistr 52, 20246, Hamburg, Germany
    Pathologe 30:179-84. 2009
    ..Targeted therapy in bladder cancer is particularly interesting, since a high number of oncogenes are activated and overexpressed (e.g. HER2 and EGFR)...
  2. doi request reprint Marked heterogeneity of ERG expression in large primary prostate cancers
    Sarah Minner
    Institute of Pathology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Mod Pathol 26:106-16. 2013
    ..Marked heterogeneity also compromises the concept of analyzing ERG status for treatment decisions in diagnostic needle core biopsies...
  3. ncbi request reprint High level of Ets-related gene expression has high specificity for prostate cancer: a tissue microarray study of 11 483 cancers
    Sarah Minner
    Institute of Pathology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Histopathology 61:445-53. 2012
    ..This study was undertaken to determine the prevalence of ERG overexpression in other tumour types as well as in normal tissues...
  4. doi request reprint Epidermal growth factor receptor protein expression and genomic alterations in renal cell carcinoma
    Sarah Minner
    Institute of Pathology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Cancer 118:1268-75. 2012
    ..Epidermal growth factor receptor (EGFR) is involved in the progression of many cancer types and represents an important therapeutic target...
  5. doi request reprint Y chromosome loss is a frequent early event in urothelial bladder cancer
    Sarah Minner
    Institute of Pathology, University Medical Center Hamburg Eppendorf, Germany
    Pathology 42:356-9. 2010
    ..The aim of this study was to further clarify the potential relevance of Y chromosome losses in bladder cancer with respect to clinical outcome and patient age...
  6. doi request reprint ERG status is unrelated to PSA recurrence in radically operated prostate cancer in the absence of antihormonal therapy
    Sarah Minner
    Institute of Pathology and Departments of Clinical Chemistry, Bone Marrow Transplantation with Section, Pneumology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Clin Cancer Res 17:5878-88. 2011
    ..A secondary aim was to search for differences between these tumor classes...
  7. doi request reprint Recurrent deletion of 3p13 targets multiple tumour suppressor genes and defines a distinct subgroup of aggressive ERG fusion-positive prostate cancers
    Antje Krohn
    Institute of Pathology, University Medical Centre Hamburg Eppendorf, Hamburg, Germany
    J Pathol 231:130-41. 2013
    ..In summary, our data show that deletion of 3p13 defines a distinct and aggressive molecular subset of ERG(+) prostate cancers, which is possibly driven by inactivation of multiple tumour suppressors...
  8. pmc High mitochondria content is associated with prostate cancer disease progression
    Katharina Grupp
    Institute of Pathology, University Medical Center Hamburg Eppendorf, Martinistr, 52, 20246 Hamburg, Germany
    Mol Cancer 12:145. 2013
    ..Mitochondria are suggested to be important organelles for cancer initiation and promotion. This study was designed to evaluate the prognostic value of MTC02, a marker for mitochondrial content, in prostate cancer...
  9. ncbi request reprint MALDI imaging on tissue microarrays identifies molecular features associated with renal cell cancer phenotype
    Stefan Steurer
    Institute of Clinical Chemistry, University Medical Center Hamburg Eppendorf, Bldg N27, Room 00 008, Martinistr 52, 20246 Hamburg, Germany
    Anticancer Res 34:2255-61. 2014
    ..To identify molecular features associated with clinico-pathological parameters in renal cell cancer...
  10. ncbi request reprint Prognostic value of alpha-methyl CoA racemase (AMACR) expression in renal cell carcinoma
    Christian Eichelberg
    Department of Urology, University Medical Center Hamburg Eppendorf, Martinistr 52, 20246, Hamburg, Germany
    World J Urol 31:847-53. 2013
    ..The aim of this study was to asses AMACR protein expression in different RCC subtypes and to investigate its prognostic significance...
  11. doi request reprint Overexpression of the chromatin remodeler death-domain-associated protein in prostate cancer is an independent predictor of early prostate-specific antigen recurrence
    Maria Christina Tsourlakis
    Institute of Pathology, University Medical Center Hamburg Eppendorf, D 20246 Hamburg, Germany
    Hum Pathol 44:1789-96. 2013
    ..Furthermore, DAXX appears to exert biologically different effects in ERG-positive and ERG-negative prostate cancers. ..
  12. doi request reprint High tissue density of FOXP3+ T cells is associated with clinical outcome in prostate cancer
    Anna Flammiger
    Department of Oncology and Hematology, University Medical Center Hamburg Eppendorf, Hubertus Wald Tumorzentrum University Cancer Center Hamburg, Martinistrasse 52, 20246 Hamburg, Germany
    Eur J Cancer 49:1273-9. 2013
    ..Our study suggests that the intratumoural presence of regulatory T cells may have substantial functional impact and may confer an adverse clinical course in prostate cancer...
  13. doi request reprint Loss of pSer2448-mTOR expression is linked to adverse prognosis and tumor progression in ERG-fusion-positive cancers
    Julia Muller
    Department of Pathology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Int J Cancer 132:1333-40. 2013
    ....
  14. ncbi request reprint NY-ESO-1 expression is tightly linked to TMPRSS2-ERG fusion in prostate cancer
    Katharina Grupp
    General, Visceral and Thoracic Surgery Department and Clinic, University Medical Center Hamburg Eppendorf, Hamburg, Germany Institute of Pathology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Prostate 74:1012-22. 2014
    ..This study was undertaken to explore the relationship of NY-ESO-1 with tumor phenotype, biochemical recurrence, and molecular subgroups in hormone-naive prostate cancers...
  15. ncbi request reprint Strong expression of the neuronal transcription factor FOXP2 is linked to an increased risk of early PSA recurrence in ERG fusion-negative cancers
    Laura Stumm
    Institute of Pathology, University Medical Center, Hamburg Eppendorf, Germany
    J Clin Pathol 66:563-8. 2013
    ..Transcription factors of the forkhead box P (FOXP1-4) family have been implicated in various human cancer types before. The relevance and role of neuronal transcription factor FOXP2 in prostate cancer is unknown...
  16. doi request reprint Low activated leukocyte cell adhesion molecule expression is associated with advanced tumor stage and early prostate-specific antigen relapse in prostate cancer
    Sarah Minner
    Institute of Pathology, University Medical Center Hamburg Eppendorf, 20246 Hamburg, Germany
    Hum Pathol 42:1946-52. 2011
    ..The abundant presence of activated leukocyte cell adhesion molecule and its membranous localization in prostate cancer epithelium make activated leukocyte cell adhesion molecule a potentially attractive structure for targeted therapy...
  17. ncbi request reprint High RNA-binding motif protein 3 expression is an independent prognostic marker in operated prostate cancer and tightly linked to ERG activation and PTEN deletions
    Katharina Grupp
    General, Visceral and Thoracic Surgery Department and Clinic, University Medical Center Hamburg Eppendorf, Hamburg, Germany Institute of Pathology, University Medical Center Hamburg Eppendorf, Hamburg, Germany Electronic address
    Eur J Cancer 50:852-61. 2014
    ..The RNA-binding motif protein 3 (RBM3) has recently been suspected as a prognostic biomarker in several cancers...
  18. doi request reprint Y chromosome losses are exceedingly rare in prostate cancer and unrelated to patient age
    Phillip R Stahl
    Institute of Pathology, University Medical Center Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
    Prostate 72:898-903. 2012
    ..This study was undertaken to investigate the frequency of Y chromosome losses and this chromosomal abnormality might play a potential role in prostate cancer...
  19. ncbi request reprint Patterns of ALK expression in different human cancer types
    Pierre Tennstedt
    Martini Clinic, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    J Clin Pathol 67:477-81. 2014
    ....
  20. doi request reprint SPINK1 expression is tightly linked to 6q15- and 5q21-deleted ERG-fusion negative prostate cancers but unrelated to PSA recurrence
    Katharina Grupp
    General, Visceral and Thoracic Surgery Department and Clinic, University Medical Center Hamburg Eppendorf, Hamburg, Germany Institute of Pathology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Prostate 73:1690-8. 2013
    ..It was the aim of this study to further study the clinical relevance of SPINK1 expression and its relationship with other key genomic alterations of prostate cancer...
  21. doi request reprint Intratumoral T but not B lymphocytes are related to clinical outcome in prostate cancer
    Anna Flammiger
    Departments of Oncology and Hematology, University Medical Center Hamburg Eppendorf, Hubertus Wald Tumorzentrum University Cancer Center Hamburg, Hamburg, Germany
    APMIS 120:901-8. 2012
    ..This study indicates that the density of T but not B cells plays a functional role in the biology of prostate cancer and may have an impact on clinical outcome in this frequent neoplasia...
  22. ncbi request reprint High lysophosphatidylcholine acyltransferase 1 expression independently predicts high risk for biochemical recurrence in prostate cancers
    Katharina Grupp
    General, Visceral and Thoracic Surgery Department and Clinic, University Medical Center Hamburg Eppendorf, Germany Institute of Pathology, University Medical Center Hamburg Eppendorf, Germany Electronic address
    Mol Oncol 7:1001-11. 2013
    ..It is concluded, that LPCAT1 measurement, either alone or in combination, may be utilized for better clinical decision-making. These data also highlight the potentially important role of lipid metabolism in prostate cancer biology...
  23. ncbi request reprint PTEN deletions are related to disease progression and unfavourable prognosis in early bladder cancer
    Inga Cordes
    Institute of Pathology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Histopathology 63:670-7. 2013
    ..This study aimed to determine the prevalence and clinical significance of deletions of the tumour suppressor gene PTEN in bladder cancer...
  24. doi request reprint Genomic deletion of MAP3K7 at 6q12-22 is associated with early PSA recurrence in prostate cancer and absence of TMPRSS2:ERG fusions
    Martina Kluth
    Institute of Pathology, University Medical Center Hamburg Eppendorf, 20246 Hamburg, Germany
    Mod Pathol 26:975-83. 2013
    ....
  25. doi request reprint CHD1 is a 5q21 tumor suppressor required for ERG rearrangement in prostate cancer
    Lia Burkhardt
    Institute of Pathology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Cancer Res 73:2795-805. 2013
    ..Our study establishes CHD1 as the 5q21 tumor suppressor gene in prostate cancer and shows a key role of this chromatin remodeling factor in prostate cancer biology...
  26. doi request reprint Genomic deletion of PTEN is associated with tumor progression and early PSA recurrence in ERG fusion-positive and fusion-negative prostate cancer
    Antje Krohn
    Institute of Pathology, Prostate Cancer Center and Section for Translational Prostate Cancer Research at the Clinic of Urology at University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Am J Pathol 181:401-12. 2012
    ....
  27. doi request reprint The impact of the number of cores on tissue microarray studies investigating prostate cancer biomarkers
    Pierre Tennstedt
    Institute of Pathology, University Medical Center, Hamburg Eppendorf, Germany
    Int J Oncol 40:261-8. 2012
    ..Multiple cores may even lead to statistical problems if unequal amounts of tissue are analyzed per tumor...
  28. ncbi request reprint The prognostic impact of high Nijmegen breakage syndrome (NBS1) gene expression in ERG-negative prostate cancers lacking PTEN deletion is driven by KPNA2 expression
    Katharina Grupp
    General, Visceral and Thoracic Surgery Department and Clinic, University Medical Center Hamburg Eppendorf, Germany Institute of Pathology, University Medical Center Hamburg Eppendorf, Germany
    Int J Cancer 135:1399-407. 2014
    ..The prognostic impact of NBS1 expression in ERG-negative, PTEN non-deleted cancers was dependent of the expression status of its interaction partner KPNA2. ..
  29. doi request reprint βIII-tubulin overexpression is an independent predictor of prostate cancer progression tightly linked to ERG fusion status and PTEN deletion
    Maria C Tsourlakis
    Institute of Pathology, University Medical Center Hamburg Eppendorf, Hamburg, Germany Electronic address
    Am J Pathol 184:609-17. 2014
    ..The significant associations with key genomic alterations of prostate cancer, such as TMPRSS2:ERG fusions and PTEN deletions, suggest interactions with several pivotal pathways involved in prostate cancer. ..
  30. doi request reprint Reduced CD147 expression is linked to ERG fusion-positive prostate cancers but lacks substantial impact on PSA recurrence in patients treated by radical prostatectomy
    Katharina Grupp
    General, Visceral and Thoracic Surgery Department and Clinic, Institute of Pathology, University Medical Center Hamburg Eppendorf, Martinistr 52, Germany Institute of Pathology, University Medical Center Hamburg Eppendorf, Martinistr 52, Germany Electronic address
    Exp Mol Pathol 95:227-34. 2013
    ..Despite a weak association with PSA recurrence, CD147 cannot be considered a relevant prognostic biomarker...
  31. doi request reprint Cysteine-rich secretory protein 3 overexpression is linked to a subset of PTEN-deleted ERG fusion-positive prostate cancers with early biochemical recurrence
    Katharina Grupp
    General, Visceral and Thoracic Surgery Department and Clinic, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Mod Pathol 26:733-42. 2013
    ..The tight link of strong CRISP3 expression to the ERG fusion-positive prostate cancers with PTEN deletions provides further evidence for the existence of molecularly distinct subgroups of prostate cancers...
  32. doi request reprint Neurovascular structure-adjacent frozen-section examination (NeuroSAFE) increases nerve-sparing frequency and reduces positive surgical margins in open and robot-assisted laparoscopic radical prostatectomy: experience after 11,069 consecutive patients
    Thorsten Schlomm
    Martini Clinic, Prostate Cancer Center, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Eur Urol 62:333-40. 2012
    ..Intraoperative frozen-section analysis allows real-time histologic assessment of surgical margins (SMs) and identification of candidates for nerve-sparing (NS) procedures...
  33. ncbi request reprint Reduced membranous MET expression is linked to bladder cancer progression
    Martina Kluth
    Institute of Pathology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Cancer Genet 207:147-52. 2014
    ..Accordingly, rare amplification of the genomic area including the MET gene was not associated with MET protein overexpression. ..
  34. doi request reprint Patterns of TPD52 overexpression in multiple human solid tumor types analyzed by quantitative PCR
    Pierre Tennstedt
    Martini Clinic, Section for Translational Prostate Cancer Research, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Int J Oncol 44:609-15. 2014
    ..These results demonstrate that TPD52 is frequently and strongly upregulated in many human cancer types, which may represent candidate tumor types for potential anti-TPD52 therapies...
  35. doi request reprint High nuclear karyopherin α 2 expression is a strong and independent predictor of biochemical recurrence in prostate cancer patients treated by radical prostatectomy
    Katharina Grupp
    1 General, Visceral and Thoracic Surgery Department and Clinic, Hamburg, Germany 2 Institute of Pathology, Hamburg, Germany
    Mod Pathol 27:96-106. 2014
    ..The data also emphasize a critical role of the functionality of the nuclear import machinery for prostate cancer biology. ..
  36. doi request reprint Reduced CD151 expression is related to advanced tumour stage in urothelial bladder cancer
    Sarah Minner
    Institute of Pathology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Pathology 44:448-52. 2012
    ..The aim of this study was to clarify the relationship of CD151 expression with tumour phenotype and clinical outcome in bladder cancer...
  37. doi request reprint Low level HER2 overexpression is associated with rapid tumor cell proliferation and poor prognosis in prostate cancer
    Sarah Minner
    Institute of Pathology, Department of Urology, Prostate Cancer Center University Medical Center, Hamburg Eppendorf, Germany
    Clin Cancer Res 16:1553-60. 2010
    ..The purpose of this study was to learn more on the prevalence and clinical significance of HER2 amplification and overexpression in prostate cancer...
  38. doi request reprint Epithelial cell adhesion molecule is an independent prognostic marker in clear cell renal carcinoma
    Christian Eichelberg
    Department of Urology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Int J Cancer 132:2948-55. 2013
    ..Our findings indicate that EPCAM is an independent prognostic molecular marker in ccRCC and, especially in localized ccRCC, might be able to provide auxiliary information for a better prognostication...
  39. ncbi request reprint Clinical significance of different types of p53 gene alteration in surgically treated prostate cancer
    Martina Kluth
    Institute of Pathology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Int J Cancer 135:1369-80. 2014
    ..Strong p53 immunostaining-most likely accompanying dominant negative or oncogenic p53 mutation-has independent prognostic relevance and may thus represent a clinical useful molecular feature of prostate cancer. ..
  40. ncbi request reprint Loss of somatostatin receptor subtype 2 in prostate cancer is linked to an aggressive cancer phenotype, high tumor cell proliferation and predicts early metastatic and biochemical relapse
    Jan K Hennigs
    Department of Pathology, University Medical Center Hamburg Eppendorf, Hamburg, Germany Department of Internal Medicine II Oncology, Hematology, BMT With Section Pneumology, Hubertus Wald Tumorzentrum University Cancer Center Hamburg UCCH University Medical Center Hamburg Eppendorf, Hamburg, Germany
    PLoS ONE 9:e100469. 2014
    ..Therefore, SSTR2 expression seems an important factor in the pathogenesis of prostate cancer and re-introduction of the receptor in SSTR2-negative prostate cancers may feature a promising target for novel gene therapy approaches. ..
  41. ncbi request reprint Continuous tissue microarray based identification of cancers with homogeneous target expression for successful targeted therapy in clinical routine practice
    Eike Burandt
    Institute of Pathology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Genes Chromosomes Cancer 53:228-39. 2014
    ..The successful treatment of one patient with homogeneously HER2 positive metastatic colorectal cancer argues for the clinical utility of this approach at least in carefully selected, homogeneous cancers...
  42. doi request reprint High level PSMA expression is associated with early PSA recurrence in surgically treated prostate cancer
    Sarah Minner
    Institute of Pathology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Prostate 71:281-8. 2011
    ..This study was undertaken, to gain more insight on the role of PSMA in early prostate cancer and its distribution in various normal tissues...
  43. doi request reprint ALCAM (CD166) expression and serum levels are markers for poor survival of esophageal cancer patients
    Michael Tachezy
    Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Int J Cancer 131:396-405. 2012
    ..In addition, ALCAM expression in a subset of DTC of the bone marrow indicates a potential function in the metastatic cascade of EC...
  44. doi request reprint Prognostic role and HER2 expression of circulating tumor cells in peripheral blood of patients prior to radical cystectomy: a prospective study
    Michael Rink
    Department of Urology, University Medical Centre Hamburg Eppendorf, Hamburg, Germany
    Eur Urol 61:810-7. 2012
    ..Preliminary research has suggested the potential prognostic value of circulating tumor cells (CTC) in patients with advanced nonmetastatic urothelial carcinoma of the bladder (UCB)...
  45. doi request reprint Older patients suffer from adverse histopathological features after radical cystectomy
    Michael Rink
    Department of Urology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Int J Urol 18:576-84. 2011
    ..Perioperative morbidity can be significant and it can represent a limitation for its indication in this population. The aim of the present study was to evaluate the outcomes of RC in elderly patients from a large single-center cohort...
  46. doi request reprint MALDI mass spectrometric imaging based identification of clinically relevant signals in prostate cancer using large-scale tissue microarrays
    Stefan Steurer
    Institute of Pathology, University Medical Center Hamburg Eppendorf, Germany
    Int J Cancer 133:920-8. 2013
    ..The combination of MSI and large-scale TMAs reflects a powerful approach enabling immediate prioritization of MSI signals based on associations with clinico-pathological and molecular data...
  47. doi request reprint Detection of circulating tumour cells in peripheral blood of patients with advanced non-metastatic bladder cancer
    Michael Rink
    Department of Urology, University Medical Centre Hamburg Eppendorf, Hamburg, Germany
    BJU Int 107:1668-75. 2011
    ..To prospectively detect and evaluate the biological significance of circulating tumour cells (CTC) in patients with bladder cancer, especially in those patients with non-metastatic, advanced bladder cancer (NMABC)...
  48. pmc No detection of XMRV in blood samples and tissue sections from prostate cancer patients in Northern Europe
    Kristin Stieler
    Institute for Medical Microbiology and Virology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    PLoS ONE 6:e25592. 2011
    ....
  49. ncbi request reprint Clinical significance of p53 alterations in surgically treated prostate cancers
    Thorsten Schlomm
    Martini Clinic, Prostate Cancer Center, University Medical Center, Hamburg Eppendorf, Germany
    Mod Pathol 21:1371-8. 2008
    ..The rate of p53 alterations increases with prostate cancer progression...
  50. doi request reprint MALDI imaging on large-scale tissue microarrays identifies molecular features associated with tumour phenotype in oesophageal cancer
    Alexander Quaas
    Institute of Pathology, University of Hamburg, Hamburg, Germany
    Histopathology 63:455-62. 2013
    ....
  51. doi request reprint Combined alpha-methylacyl coenzyme A racemase/p53 analysis to identify dysplasia in inflammatory bowel disease
    Andreas Marx
    Institute of Pathology, University Medical Center Hamburg Eppendorf, 20246 Hamburg, Germany
    Hum Pathol 40:166-73. 2009
    ..It is concluded that combined alpha-methylacyl coenzyme A racemase/p53 analysis may represent a helpful tool to confirm dysplasia in inflammatory bowel disease...
  52. doi request reprint O-GlcNAc transferase integrates metabolic pathways to regulate the stability of c-MYC in human prostate cancer cells
    Harri M Itkonen
    Prostate Research Group, Centre for Molecular Medicine Norway, Nordic EMBL Partnership, University of Oslo and Oslo University Hospital, Oslo, Norway
    Cancer Res 73:5277-87. 2013
    ..Our findings identify HBP as a modulator of prostate cancer growth and c-MYC as a key target of OGT function in prostate cancer cells...