W Miekisch

Summary

Affiliation: University of Rostock
Country: Germany

Publications

  1. ncbi request reprint Analysis of volatile disease markers in blood
    W Miekisch
    Department of Anesthesiology and Intensive Care Medicine, University Hospital of Rostock, Schillingallee 35, 18057 Rostock, Germany
    Clin Chem 47:1053-60. 2001
  2. doi request reprint Assessment of propofol concentrations in human breath and blood by means of HS-SPME-GC-MS
    Wolfram Miekisch
    Department of Anesthesia and Intensive Care, University of Rostock, Schillingallee 35, 18057 Rostock Germany
    Clin Chim Acta 395:32-7. 2008
  3. ncbi request reprint Diagnostic potential of breath analysis--focus on volatile organic compounds
    Wolfram Miekisch
    Department of Anaesthesia and Intensive Care Medicine, University Hospital of Rostock, Rostock, Germany
    Clin Chim Acta 347:25-39. 2004
  4. ncbi request reprint Impact of inspired substance concentrations on the results of breath analysis in mechanically ventilated patients
    J K Schubert
    Department of Anaesthesiology and Intensive Care, University of Rostock, Rostock, Germany
    Biomarkers 10:138-52. 2005
  5. ncbi request reprint Determination of antibiotic drug concentrations in circulating human blood by means of solid phase micro-extraction
    Jochen K Schubert
    Department of Anaesthesia and Intensive Care, University of Rostock, 18057 Rostock, Germany
    Clin Chim Acta 386:57-62. 2007
  6. ncbi request reprint A novel visually CO2 controlled alveolar breath sampling technique
    Thomas Birken
    University of Rostock, Department of Anaesthesiology and Intensive Care, Rostock, Germany
    Technol Health Care 14:499-506. 2006
  7. ncbi request reprint The extent of induction of CYP3A by St. John's wort varies among products and is linked to hyperforin dose
    Silke C Mueller
    Center of Pharmacology and Toxicology, Institute of Clinical Pharmacology, University of Rostock, Schillingallee 70, 18057, Rostock, Germany
    Eur J Clin Pharmacol 62:29-36. 2006
  8. ncbi request reprint Breath analysis in critically ill patients: potential and limitations
    Jochen K Schubert
    Department of Anaesthesiology and Intensive Care, University of Rostock, Schillingallee 35, 18057 Rostock, Germany
    Expert Rev Mol Diagn 4:619-29. 2004
  9. ncbi request reprint Breath markers and soluble lipid peroxidation markers in critically ill patients
    Joachim Scholpp
    Department of Anaesthesia, University Hospital of Freiburg, Germany
    Clin Chem Lab Med 40:587-94. 2002
  10. ncbi request reprint Lipid peroxidation early after brain injury
    Joachim Scholpp
    Department of Anesthesia, University Hospital of Freiburg, Freiburg i Brsg, Germany
    J Neurotrauma 21:667-77. 2004

Collaborators

Detail Information

Publications12

  1. ncbi request reprint Analysis of volatile disease markers in blood
    W Miekisch
    Department of Anesthesiology and Intensive Care Medicine, University Hospital of Rostock, Schillingallee 35, 18057 Rostock, Germany
    Clin Chem 47:1053-60. 2001
    ..To overcome this problem, we developed a method to assess trace amounts of hydrocarbons (pentane and isoprene), ketones (acetone), halogenated compounds (isoflurane), and thioethers (dimethyl sulfide) in the blood of humans and animals...
  2. doi request reprint Assessment of propofol concentrations in human breath and blood by means of HS-SPME-GC-MS
    Wolfram Miekisch
    Department of Anesthesia and Intensive Care, University of Rostock, Schillingallee 35, 18057 Rostock Germany
    Clin Chim Acta 395:32-7. 2008
    ....
  3. ncbi request reprint Diagnostic potential of breath analysis--focus on volatile organic compounds
    Wolfram Miekisch
    Department of Anaesthesia and Intensive Care Medicine, University Hospital of Rostock, Rostock, Germany
    Clin Chim Acta 347:25-39. 2004
    ..Analytical procedures, issues concerning biochemistry and exhalation mechanisms of volatile substances, and future developments will be discussed...
  4. ncbi request reprint Impact of inspired substance concentrations on the results of breath analysis in mechanically ventilated patients
    J K Schubert
    Department of Anaesthesiology and Intensive Care, University of Rostock, Rostock, Germany
    Biomarkers 10:138-52. 2005
    ..Hence, substances having inspired concentrations>5% of expired concentrations should not be used as breath markers in these patients without knowledge of concentrations in blood and breath...
  5. ncbi request reprint Determination of antibiotic drug concentrations in circulating human blood by means of solid phase micro-extraction
    Jochen K Schubert
    Department of Anaesthesia and Intensive Care, University of Rostock, 18057 Rostock, Germany
    Clin Chim Acta 386:57-62. 2007
    ..This study was intended to extend this technique to a clinically relevant antibiotic drug under close to physiological conditions in human blood...
  6. ncbi request reprint A novel visually CO2 controlled alveolar breath sampling technique
    Thomas Birken
    University of Rostock, Department of Anaesthesiology and Intensive Care, Rostock, Germany
    Technol Health Care 14:499-506. 2006
    ..Monitoring of expired CO2 can be used to identify alveolar gas. The purpose of this study was to evaluate a bed side version of this technique using visual CO2 control by means of a capnometer...
  7. ncbi request reprint The extent of induction of CYP3A by St. John's wort varies among products and is linked to hyperforin dose
    Silke C Mueller
    Center of Pharmacology and Toxicology, Institute of Clinical Pharmacology, University of Rostock, Schillingallee 70, 18057, Rostock, Germany
    Eur J Clin Pharmacol 62:29-36. 2006
    ..Since SJW products vary in the amount of HYF and other main constituents, the aim of the study was to evaluate the effect on CYP3A function of SJW preparations with a range from very low to high HYF content...
  8. ncbi request reprint Breath analysis in critically ill patients: potential and limitations
    Jochen K Schubert
    Department of Anaesthesiology and Intensive Care, University of Rostock, Schillingallee 35, 18057 Rostock, Germany
    Expert Rev Mol Diagn 4:619-29. 2004
    ..Analytical procedures, problems concerning the physiologic meaning of breath markers and future developments will be discussed...
  9. ncbi request reprint Breath markers and soluble lipid peroxidation markers in critically ill patients
    Joachim Scholpp
    Department of Anaesthesia, University Hospital of Freiburg, Germany
    Clin Chem Lab Med 40:587-94. 2002
    ..More detailed insights into inflammatory processes can be obtained when the volatile markers and the serum markers are considered together...
  10. ncbi request reprint Lipid peroxidation early after brain injury
    Joachim Scholpp
    Department of Anesthesia, University Hospital of Freiburg, Freiburg i Brsg, Germany
    J Neurotrauma 21:667-77. 2004
    ..n-Pentane seems to be a valuable marker to detect lipid peroxidation early after brain trauma. Malondialdehyde may be of value only later in the course of the disease. TBARS are not a specific marker and should therefore not be used...
  11. doi request reprint Intercomparison of infrared cavity leak-out spectroscopy and gas chromatography-flame ionization for trace analysis of ethane
    Sven Thelen
    Institut fur Lasermedizin, Universitat Dusseldorf, Universitatstrasse 1, 40225 Dusseldorf, Germany
    Anal Chem 80:2768-73. 2008
    ..This opens new analytical possibilities, e.g., for real-time monitoring of ethane traces in exhaled human breath...
  12. doi request reprint Breath isoprene--aspects of normal physiology related to age, gender and cholesterol profile as determined in a proton transfer reaction mass spectrometry study
    Ievgeniia Kushch
    Department of Anaesthesiology and Critical Care Medicine, Innsbruck Medical University, Innsbruck, Austria
    Clin Chem Lab Med 46:1011-8. 2008
    ..Our cohort consisted of 205 adult volunteers of different smoking background without health complaints. Total cholesterol in blood serum was measured in 79 of these volunteers...