A Michalsen

Summary

Affiliation: University of Essen
Country: Germany

Publications

  1. pmc Checklist for the qualitative evaluation of clinical studies with particular focus on external validity and model validity
    Gudrun Bornhöft
    Witten Herdecke University, Gerhard Kienle Weg 4, Herdecke, Germany
    BMC Med Res Methodol 6:56. 2006
  2. ncbi request reprint [Effects of nutritional factors on haemostasis]
    A Michalsen
    Abteilung Innere Medizin V, Integrative Medizin, Lehrstuhl Naturheilkunde der Universitätsklinik Essen, Am Deimelsberg 34a, 45276 Essen
    Hamostaseologie 25:13-7. 2005
  3. ncbi request reprint [Glycotoxins and cellular dysfunction. A new mechanism for understanding the preventive effects of lifestyle modifications]
    A Michalsen
    Abteilung Innere Medizin, Naturheilkunde und Integrative Medizin, Kliniken Essen Mitte, Am Deimelsberg 34a, 45276 Essen, BRD
    Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 49:773-9. 2006
  4. ncbi request reprint Incorporation of fasting therapy in an integrative medicine ward: evaluation of outcome, safety, and effects on lifestyle adherence in a large prospective cohort study
    Andreas Michalsen
    Department of Integrative and Internal Medicine V, Kliniken Essen Mitte, and Complementary and Integrative Medicine of the Alfred Krupp von Bohlen und Halbach Foundation, University Duisburg Essen, Essen, Germany
    J Altern Complement Med 11:601-7. 2005
  5. ncbi request reprint Psychological and quality-of-life outcomes from a comprehensive stress reduction and lifestyle program in patients with coronary artery disease: results of a randomized trial
    Andreas Michalsen
    Kliniken Essen Mitte, Chair of Complementary and Integrative Medicine of the University Duisburg Essen, Department of Internal Medicine V and Integrative Medicine, Essen, Germany
    Psychother Psychosom 74:344-52. 2005
  6. ncbi request reprint Prolonged fasting in patients with chronic pain syndromes leads to late mood-enhancement not related to weight loss and fasting-induced leptin depletion
    Andreas Michalsen
    Department of Internal Medicine V, University Duisburg Essen, Kliniken Essen Mitte, Am Deimelsberg 34 a, 45276 Essen, Germany
    Nutr Neurosci 9:195-200. 2006
  7. ncbi request reprint Mediterranean diet has no effect on markers of inflammation and metabolic risk factors in patients with coronary artery disease
    A Michalsen
    Department of Internal Medicine V, Kliniken Essen Mitte, University Duisburg Essen, Germany
    Eur J Clin Nutr 60:478-85. 2006
  8. ncbi request reprint Rapid stress reduction and anxiolysis among distressed women as a consequence of a three-month intensive yoga program
    Andreas Michalsen
    Department of Integrative and Internal Medicine V, Kliniken Essen Mitte, Chair of Complementary Medicine at the University Duisburg Essen, Germany
    Med Sci Monit 11:CR555-561. 2005
  9. pmc Mediterranean diet or extended fasting's influence on changing the intestinal microflora, immunoglobulin A secretion and clinical outcome in patients with rheumatoid arthritis and fibromyalgia: an observational study
    Andreas Michalsen
    Kliniken Essen Mitte, Department of Internal and Integrative Medicine, University Duisburg Essen, Am Deimelsberg 34a, 45276 Essen, Germany
    BMC Complement Altern Med 5:22. 2005
  10. ncbi request reprint Effects of lifestyle modification on the progression of coronary atherosclerosis, autonomic function, and angina--the role of GNB3 C825T polymorphism
    Andreas Michalsen
    Abteilung Innere Medizin V, Kliniken Essen Mitte, Germany
    Am Heart J 151:870-7. 2006

Detail Information

Publications43

  1. pmc Checklist for the qualitative evaluation of clinical studies with particular focus on external validity and model validity
    Gudrun Bornhöft
    Witten Herdecke University, Gerhard Kienle Weg 4, Herdecke, Germany
    BMC Med Res Methodol 6:56. 2006
    ..Although tools for its evaluation have been established, there is a lack of awareness of their significance and application. In this article, a comprehensive checklist is presented addressing these relevant criteria...
  2. ncbi request reprint [Effects of nutritional factors on haemostasis]
    A Michalsen
    Abteilung Innere Medizin V, Integrative Medizin, Lehrstuhl Naturheilkunde der Universitätsklinik Essen, Am Deimelsberg 34a, 45276 Essen
    Hamostaseologie 25:13-7. 2005
    ..In the clinical context, mediterranean diet may exert its beneficial effects through synergistic action on haemostasis, endothelial function and vascular inflammation...
  3. ncbi request reprint [Glycotoxins and cellular dysfunction. A new mechanism for understanding the preventive effects of lifestyle modifications]
    A Michalsen
    Abteilung Innere Medizin, Naturheilkunde und Integrative Medizin, Kliniken Essen Mitte, Am Deimelsberg 34a, 45276 Essen, BRD
    Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 49:773-9. 2006
    ..The clinical impact of low-AGE diets and fasting and the interaction between stress and food intake should be further investigated in controlled trials...
  4. ncbi request reprint Incorporation of fasting therapy in an integrative medicine ward: evaluation of outcome, safety, and effects on lifestyle adherence in a large prospective cohort study
    Andreas Michalsen
    Department of Integrative and Internal Medicine V, Kliniken Essen Mitte, and Complementary and Integrative Medicine of the Alfred Krupp von Bohlen und Halbach Foundation, University Duisburg Essen, Essen, Germany
    J Altern Complement Med 11:601-7. 2005
    ..The aim of this study was to implement fasting therapy in an inpatient integrative medicine ward and to evaluate safety, acceptance, and effects on health-related outcomes and lifestyle adherence...
  5. ncbi request reprint Psychological and quality-of-life outcomes from a comprehensive stress reduction and lifestyle program in patients with coronary artery disease: results of a randomized trial
    Andreas Michalsen
    Kliniken Essen Mitte, Chair of Complementary and Integrative Medicine of the University Duisburg Essen, Department of Internal Medicine V and Integrative Medicine, Essen, Germany
    Psychother Psychosom 74:344-52. 2005
    ..Given recent significant improvements in cardiac care, we evaluated the current benefit of stress reduction/lifestyle modification on QoL and emotional distress in patients with coronary artery disease (CAD)...
  6. ncbi request reprint Prolonged fasting in patients with chronic pain syndromes leads to late mood-enhancement not related to weight loss and fasting-induced leptin depletion
    Andreas Michalsen
    Department of Internal Medicine V, University Duisburg Essen, Kliniken Essen Mitte, Am Deimelsberg 34 a, 45276 Essen, Germany
    Nutr Neurosci 9:195-200. 2006
    ..Our findings suggest that fasting induces specific mood-enhancement. The physiological mediator appears to be neither leptin nor cortisol, the role of other mechanisms has to be further studied...
  7. ncbi request reprint Mediterranean diet has no effect on markers of inflammation and metabolic risk factors in patients with coronary artery disease
    A Michalsen
    Department of Internal Medicine V, Kliniken Essen Mitte, University Duisburg Essen, Germany
    Eur J Clin Nutr 60:478-85. 2006
    ..We therefore investigated the effect of Mediterranean diet on markers of inflammation and metabolic risk factors in patients with treated CAD...
  8. ncbi request reprint Rapid stress reduction and anxiolysis among distressed women as a consequence of a three-month intensive yoga program
    Andreas Michalsen
    Department of Integrative and Internal Medicine V, Kliniken Essen Mitte, Chair of Complementary Medicine at the University Duisburg Essen, Germany
    Med Sci Monit 11:CR555-561. 2005
    ..We aimed to evaluate potential effects of Iyengar Hatha yoga on perceived stress and associated psychological outcomes in mentally distressed women...
  9. pmc Mediterranean diet or extended fasting's influence on changing the intestinal microflora, immunoglobulin A secretion and clinical outcome in patients with rheumatoid arthritis and fibromyalgia: an observational study
    Andreas Michalsen
    Kliniken Essen Mitte, Department of Internal and Integrative Medicine, University Duisburg Essen, Am Deimelsberg 34a, 45276 Essen, Germany
    BMC Complement Altern Med 5:22. 2005
    ....
  10. ncbi request reprint Effects of lifestyle modification on the progression of coronary atherosclerosis, autonomic function, and angina--the role of GNB3 C825T polymorphism
    Andreas Michalsen
    Abteilung Innere Medizin V, Kliniken Essen Mitte, Germany
    Am Heart J 151:870-7. 2006
    ....
  11. ncbi request reprint [Nicotine withdrawal in hospital coworkers: opportunities instead of prohibitions]
    Andreas Michalsen
    Kliniken Essen Mitte, Abteilung Innere Medizin V, Naturheilkunde und Integrative Medizin, Am Deimelsberg 34 a, 45276 Essen
    Pflege Z 56:507-11. 2003
  12. ncbi request reprint The short-term effects of fasting on the neuroendocrine system in patients with chronic pain syndromes
    A Michalsen
    Department of Internal Medicine V and Integrative Medicine, Kliniken Essen Mitte, Am Deimelsberg 34 a, 45276 Essen, Germany
    Nutr Neurosci 6:11-8. 2003
    ..Our results show that short-term fasting leads to neuroendocrine activation and may suggest that the extent of this response is dependent on the individual metabolic and endocrine state at baseline...
  13. ncbi request reprint Effects of short-term modified fasting on sleep patterns and daytime vigilance in non-obese subjects: results of a pilot study
    A Michalsen
    Department of Internal Medicine V, Kliniken Essen Mitte, Essen, Germany
    Ann Nutr Metab 47:194-200. 2003
    ..The effects of a home-based 1-week modified fasting on sleep patterns and daytime vigilance and performance were analysed in 15 healthy non-obese volunteers...
  14. doi request reprint Impact of stimulation dose and personality on autonomic and psychological effects induced by acupuncture
    M Backer
    Department of Complementary and Integrative Medicine, University of Duisburg Essen, Kliniken Essen Mitte, Germany
    Auton Neurosci 170:48-55. 2012
    ..After needle insertion subjects who tend to augment incoming stimuli might show a lack of psychological relaxation when receiving high dose stimulation...
  15. ncbi request reprint [Short-term therapeutic fasting in the treatment of chronic pain and fatigue syndromes--well-being and side effects with and without mineral supplements]
    A Michalsen
    Abteilung für Innere Medizin V, Naturheilkunde und Integrative Medizin, Kliniken Essen Mitte, Essen
    Forsch Komplementarmed Klass Naturheilkd 9:221-7. 2002
    ..Mineral supplements are frequently used in order to compensate for fasting-induced tissue acidosis and to reduce side effects. There are only limited data that support this practice...
  16. doi request reprint [Alternative and complementary therapies in fibromyalgia syndrome]
    J Langhorst
    Klinik für Innere Medizin V, Naturheilkunde und Integrative Medizin, Kliniken Essen Mitte, Am Deimelsberg 34a, 45276 Essen
    Schmerz 22:324-33. 2008
    ..Interdisciplinary S3 level guidelines were devised in cooperation with 8 medical, 2 psychological and 2 patient support groups. Results were elaborated in a multilevel group process...
  17. ncbi request reprint A functional GNAS promoter polymorphism is associated with altered weight loss during short-term fasting
    U H Frey
    Institut für Pharmakogenetik, Universitatsklinikum, Essen, Germany
    Eur J Med Res 13:576-8. 2008
    ..2 +/- 1.2, n = 9; p = 0.0003). The present study reconfirms our earlier reported findings and suggests that GNAS genotypes also influence weight loss during short-term fasting. related to a low vascular density (CD31 expression) in CDC...
  18. ncbi request reprint [Acupuncture in the treatment of pain--hypothesis to adaptive effects]
    M Backer
    Klinik für Innere Medizin V Naturheilkunde und Integrative Medizin, Essen
    Forsch Komplementarmed Klass Naturheilkd 11:335-45. 2004
    ....
  19. ncbi request reprint [Health-related control belief and quality of life in chronically ill patients after a behavioral intervention in an integrative medicine clinic--an observational study]
    B Hoffmann
    Institut für Medizinische Informatik, Biometrie und Epidemiologie, Universitatsklinikum Essen, Germany
    Forsch Komplementarmed Klass Naturheilkd 11:159-70. 2004
    ..The goal is to increase health-related quality of life (QoL) as well as control beliefs and to reduce morbidity in later life...
  20. ncbi request reprint [Complementary treatment of pneumonia with pleural effusion]
    Thomas Rampp
    Kliniken Essen Mitte Knappschafts Krankenhaus, Innere Medizin V Naturheikunde und Integrative Medizin, Essen, Deutschland corrected
    Forsch Komplementmed 13:116-8. 2006
    ..The multimodal CAM treatment resulted in a rapid clinical and x-ray resolution of pneumonia, and cantharidin treatment effectively relieved pain. The case and the potential of topical cantharidin in pain syndromes are discussed...
  21. doi request reprint Acupuncture in migraine: investigation of autonomic effects
    Marcus Backer
    Complementary and Integrative Medicine, Department of Internal Medicine V, University of Duisburg Essen, Kliniken Essen Mitte, Germany
    Clin J Pain 24:106-15. 2008
    ..As acupuncture has been shown to exhibit considerable autonomic effects, we tested whether the clinical effects of acupuncture in migraine prophylaxis are mediated by changes of the autonomic regulation...
  22. ncbi request reprint Effects of mind-body therapy on quality of life and neuroendocrine and cellular immune functions in patients with ulcerative colitis
    Sigrid Elsenbruch
    Departement of Medical Psychology, University Clinic of Essen, Essen, Germany
    Psychother Psychosom 74:277-87. 2005
    ..The aim of this study was to investigate the effects of mind-body therapy on neuroendocrine and cellular immune measures, health-related quality of life and disease activity in patients with ulcerative colitis (UC) in remission...
  23. ncbi request reprint Thermal hydrotherapy improves quality of life and hemodynamic function in patients with chronic heart failure
    Andreas Michalsen
    Kliniken Essen Mitte, Department of Internal Medicine V, Essen, Germany
    Am Heart J 146:728-33. 2003
    ..European hydrotherapy (according to Kneipp) additionally uses short cold water stimuli, which lead to prolonged vasodilation and adaptive responses. Studies on the efficacy of hydrotherapy in chronic heart failure are lacking...
  24. ncbi request reprint [Mind-body medicine as a part of German integrative medicine]
    G Dobos
    Stiftungslehrstuhl für Naturheilkunde der Alfried Krupp von Bohlen und Halbach Stiftung, Universitat Duisburg Essen, Kliniken Essen Mitte, Am Deimelsberg 34a, 45276 Essen, BRD
    Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 49:723-8. 2006
    ..Considering that a growing number of health issues arises due to maladaptive lifestyles, MBM is being identified as a development that supports a shift from increasingly expensive treatments to more cost-effective preventive approaches...
  25. ncbi request reprint [Smoking cessation for hospital staff. A controlled intervention study]
    A Michalsen
    Abt für Innere Medizin V und Integrative Medizin, Kliniken Essen Mitte, Germany
    Dtsch Med Wochenschr 127:1742-7. 2002
    ....
  26. ncbi request reprint Effects of a comprehensive lifestyle modification program on quality-of-life in patients with ulcerative colitis: a twelve-month follow-up
    Jost Langhorst
    University of Duisburg Essen, Kliniken Essen Mitte, Germany
    Scand J Gastroenterol 42:734-45. 2007
    ....
  27. ncbi request reprint Patterns of complementary and alternative medicine (CAM) use in patients with inflammatory bowel disease: perceived stress is a potential indicator for CAM use
    Jost Langhorst
    University of Duisburg Essen, Department of Internal Medicine, Chair of Complementary and Integrative Medicine, Kliniken Essen Mitte, Am Deimelsberg 34a, D 45276 Essen, Germany
    Complement Ther Med 15:30-7. 2007
    ....
  28. doi request reprint Randomised clinical trial: a herbal preparation of myrrh, chamomile and coffee charcoal compared with mesalazine in maintaining remission in ulcerative colitis - a double-blind, double-dummy study
    J Langhorst
    Department for Integrative Gastroenterology, Kliniken Essen Mitte, University of Duisburg Essen, Essen, Germany Department for Internal and Integrative Medicine, Kliniken Essen Mitte, University of Duisburg Essen, Essen, Germany
    Aliment Pharmacol Ther 38:490-500. 2013
    ..Aminosalicylates are used as standard treatment for maintaining remission in ulcerative colitis (UC)...
  29. ncbi request reprint Noninvasive markers in the assessment of intestinal inflammation in inflammatory bowel diseases: performance of fecal lactoferrin, calprotectin, and PMN-elastase, CRP, and clinical indices
    Jost Langhorst
    Department of Internal and Integrative Medicine, Kliniken Essen Mitte, University of Duisburg Essen, Germany
    Am J Gastroenterol 103:162-9. 2008
    ....
  30. doi request reprint Elevated human beta-defensin-2 levels indicate an activation of the innate immune system in patients with irritable bowel syndrome
    Jost Langhorst
    Department of Internal Medicine, University of Duisburg Essen, Kliniken Essen Mitte, Essen, Germany
    Am J Gastroenterol 104:404-10. 2009
    ..Recent results imply that HBD-2 is expressed in active intestinal inflammation, especially in ulcerative colitis (UC). Our aim was to evaluate fecal measurements of HBD-2 in patients with active UC and IBS, and in healthy controls (HCs)...
  31. ncbi request reprint Comparison of 4 neutrophil-derived proteins in feces as indicators of disease activity in ulcerative colitis
    Jost Langhorst
    Department of Internal Medicine, Kliniken Essen Mitte, University of Duisburg Essen, Essen, Germany
    Inflamm Bowel Dis 11:1085-91. 2005
    ....
  32. ncbi request reprint Leech therapy for symptomatic treatment of knee osteoarthritis: results and implications of a pilot study
    Andreas Michalsen
    Department of Internal and Integrative Medicine, Kliniken Essen Mitte, Germany
    Altern Ther Health Med 8:84-8. 2002
    ..There is renewed interest in leech therapy in the field of complementary medicine and empirical evidence for specific benefit in knee osteoarthritis...
  33. ncbi request reprint Amount of systemic steroid medication is a strong predictor for the use of complementary and alternative medicine in patients with inflammatory bowel disease: results from a German national survey
    Jost Langhorst
    Department of Internal Medicine, Kliniken Essen Mitte, Germany
    Inflamm Bowel Dis 11:287-95. 2005
    ..To further elucidate this phenomenon, we sent questionnaires to a large sample of IBD patients in Germany to determine the patterns and predictors of their CAM use...
  34. ncbi request reprint Effectiveness of leech therapy in osteoarthritis of the knee: a randomized, controlled trial
    Andreas Michalsen
    Kliniken Essen Mitte, Academic Teaching Hospital of the University of Duisburg Essen, Karl and Veronica Carstens Foundation, and Institute for Medical Informatics, Biometry and Epidemiology, University of Duisburg Essen, Essen, Germany
    Ann Intern Med 139:724-30. 2003
    ..Leech therapy was commonly used in traditional medicine for treating localized pain. Clinically significant pain relief after leech therapy for osteoarthritis of the knee has been demonstrated by preliminary data...
  35. ncbi request reprint MR colonography without bowel purgation for the assessment of inflammatory bowel diseases: diagnostic accuracy and patient acceptance
    Jost Langhorst
    Department of Internal and Integrative Medicine, Kliniken Essen Mitte, Germany
    Inflamm Bowel Dis 13:1001-8. 2007
    ..In addition, patient acceptance was compared with conventional colonoscopy (CC)...
  36. doi request reprint [Pain-relieving effect of cantharidin blister on lumbar spinal stenosis]
    Thomas Rampp
    Innere Medizin V, Naturheilkunde und Integrative Medizin, Kliniken Essen Mitte Knappschafts Krankenhaus, Essen, Deutschland
    Forsch Komplementmed 16:246-50. 2009
    ..We tested the pain-relieving effect of lumbar cantharidin blisters in a non-randomised controlled pilot study...
  37. doi request reprint Effectiveness of leech therapy in women with symptomatic arthrosis of the first carpometacarpal joint: a randomized controlled trial
    Andreas Michalsen
    Department of Internal and Integrative Medicine, Kliniken Essen Mitte, Academic Teaching Hospital, Am Deimelsberg 34a, 45276 Essen, Germany
    Pain 137:452-9. 2008
    ..A single course of leech therapy is effective in relieving pain, improving disability and QoL for at least 2 months. The potential of leech therapy for treatment of arthritic pain and underlying mechanisms should be further investigated...
  38. doi request reprint Functional chronic pain syndromes and naturopathic treatments: neurobiological foundations
    Frauke Musial
    Alfried Krupp von Bohlen und Halbach Foundation, University of Duisburg Essen, Germany
    Forsch Komplementmed 15:97-103. 2008
    ..Further clarification of the mechanisms of action of reflex therapies will support their clinical evidence and add to our understanding of the neurobiology of complementary medicine...
  39. doi request reprint Effects of rhythmic embrocation therapy with solum oil in chronic pain patients: a prospective observational study
    Thomas Ostermann
    Department of Medical Theory and Complementary Medicine, University of Witten, Germany
    Clin J Pain 24:237-43. 2008
    ..The present study evaluates the therapeutic effects of rhythmic embrocation with a lavender/peat extract [Solum Oil (German: Solum Ol)]...
  40. ncbi request reprint Heart rate reduction through lifestyle modification
    Andreas Michalsen
    Eur Heart J 26:1806-7; author reply 1807-8. 2005
  41. ncbi request reprint [Endocannabinoids as molecular instruments of health promotion]
    Tobias Esch
    Studiengang der Integrierenden Gesundheitsförderung, Hochschule für Angewandte Wissenschaften Coburg, Friedrich Streib Str 2, D 96450 Coburg
    Med Monatsschr Pharm 29:397-403. 2006
    ..This leads to an interesting research potential, particularly when one considers the long-term effects of applied health promotion and its coupling to motivational neurobiological phenomena...
  42. ncbi request reprint The effect of Gua Sha treatment on the microcirculation of surface tissue: a pilot study in healthy subjects
    Arya Nielsen
    Beth Israel Medical Center s Continuum Center for Health and Healing, New York, NY, USA
    Explore (NY) 3:456-66. 2007
    ..There are case reports in Western literature but no studies on the physiological effects of Gua Sha...
  43. ncbi request reprint [Who represents natural and complementary and alternative medicine?]
    Andreas Michalsen
    Forsch Komplementmed 14:272-3. 2007