A T Mehlhorn

Summary

Affiliation: University of Freiburg
Country: Germany

Publications

  1. ncbi request reprint Mesenchymal stem cells maintain TGF-beta-mediated chondrogenic phenotype in alginate bead culture
    A T Mehlhorn
    Department of Orthopaedic and Trauma Surgery, Albert Ludwigs University Freiburg, Freiburg, Germany
    Tissue Eng 12:1393-403. 2006
  2. ncbi request reprint Clinical evaluation of a new custom offset shoulder prosthesis for treatment of complex fractures of the proximal humerus
    Alexander T Mehlhorn
    Department of Orthopaedic and Trauma Surgery, Albert Ludwigs University Freiburg, Germany
    Acta Orthop Belg 72:387-94. 2006
  3. ncbi request reprint Alendronate decreases TRACP 5b activity in osteoarthritic bone
    Alexander T Mehlhorn
    Department of Orthopaedic and Trauma Surgery, Albert Ludwigs Universitat Freiburg, Hugstetterstr, 55 79106 Freiburg, Germany
    Eur J Med Res 13:21-5. 2008
  4. ncbi request reprint Seizure-induced muscle force can caused lumbar spine fracture
    A T Mehlhorn
    Department of Orthopaedics and Trauma Surgery, Albert Ludwigs University Freiburg, Freiburg, Germany
    Acta Chir Orthop Traumatol Cech 74:202-5. 2007
  5. ncbi request reprint Differential effects of BMP-2 and TGF-beta1 on chondrogenic differentiation of adipose derived stem cells
    A T Mehlhorn
    Department of Orthopaedic and Trauma Surgery, University Medical Center Freiberg, Germany
    Cell Prolif 40:809-23. 2007
  6. ncbi request reprint bFGF influences human articular chondrocyte differentiation
    H Schmal
    Department of Orthopedics and Traumatology, University of Freiburg Medical Center, Freiburg, Germany
    Cytotherapy 9:184-93. 2007
  7. ncbi request reprint Differential expression pattern of extracellular matrix molecules during chondrogenesis of mesenchymal stem cells from bone marrow and adipose tissue
    A T Mehlhorn
    Department of Orthopaedic and Trauma Surgery, University Medical Center, Albert Ludwigs University, Freiburg, Germany
    Tissue Eng 12:2853-62. 2006
  8. ncbi request reprint Survival of human mesenchymal stromal cells from bone marrow and adipose tissue after xenogenic transplantation in immunocompetent mice
    P Niemeyer
    Department of Orthopedic Surgery and Traumatology, Freiburg University Hospital, Freiburg, Germany
    Cytotherapy 10:784-95. 2008
  9. ncbi request reprint Stimulation of chondrocytes in vitro by gene transfer with plasmids coding for epidermal growth factor (hEGF) and basic fibroblast growth factor (bFGF)
    H Schmal
    Department of Orthopedics and Traumatology, University of Freiburg Medical Center, Freiburg, Germany
    Cytotherapy 7:292-300. 2005
  10. doi request reprint Percutaneous iliosacral screw insertion: malpositioning and revision rate of screws with regards to application technique (navigated vs. Conventional)
    J Zwingmann
    Department of Orthopaedic and Trauma Surgery, University of Freiburg Medical Center, Freiburg, Germany
    J Trauma 69:1501-6. 2010

Detail Information

Publications11

  1. ncbi request reprint Mesenchymal stem cells maintain TGF-beta-mediated chondrogenic phenotype in alginate bead culture
    A T Mehlhorn
    Department of Orthopaedic and Trauma Surgery, Albert Ludwigs University Freiburg, Freiburg, Germany
    Tissue Eng 12:1393-403. 2006
    ..These findings give rise to a better understanding of the behavior of cartilage grafts affected by local factors of osteochondral transplantation sites in vivo...
  2. ncbi request reprint Clinical evaluation of a new custom offset shoulder prosthesis for treatment of complex fractures of the proximal humerus
    Alexander T Mehlhorn
    Department of Orthopaedic and Trauma Surgery, Albert Ludwigs University Freiburg, Germany
    Acta Orthop Belg 72:387-94. 2006
    ..These results emphasise the importance of a careful initial decision to select the most appropriate treatment modality in complex fractures of the proximal humerus...
  3. ncbi request reprint Alendronate decreases TRACP 5b activity in osteoarthritic bone
    Alexander T Mehlhorn
    Department of Orthopaedic and Trauma Surgery, Albert Ludwigs Universitat Freiburg, Hugstetterstr, 55 79106 Freiburg, Germany
    Eur J Med Res 13:21-5. 2008
    ..Consequently, they are more effective in areas of well-supplied bone than in osteoarthritic bone tissue...
  4. ncbi request reprint Seizure-induced muscle force can caused lumbar spine fracture
    A T Mehlhorn
    Department of Orthopaedics and Trauma Surgery, Albert Ludwigs University Freiburg, Freiburg, Germany
    Acta Chir Orthop Traumatol Cech 74:202-5. 2007
    ..Seizures-induced injuries can appear clinically asymptomatic and can easily be overseen due to absence of trauma and post-ictal impairment of consciousness...
  5. ncbi request reprint Differential effects of BMP-2 and TGF-beta1 on chondrogenic differentiation of adipose derived stem cells
    A T Mehlhorn
    Department of Orthopaedic and Trauma Surgery, University Medical Center Freiberg, Germany
    Cell Prolif 40:809-23. 2007
    ..TGF-beta1 was expected to modulate the BMP-2-induced effects through transcriptional regulation of Dlx-5, Msx-2 and Runx-2...
  6. ncbi request reprint bFGF influences human articular chondrocyte differentiation
    H Schmal
    Department of Orthopedics and Traumatology, University of Freiburg Medical Center, Freiburg, Germany
    Cytotherapy 9:184-93. 2007
    ..The possible functional role of basic fibroblast growth factor (bFGF) in regulating the mitotic and metabolic activity of primary human articular chondrocytes was investigated...
  7. ncbi request reprint Differential expression pattern of extracellular matrix molecules during chondrogenesis of mesenchymal stem cells from bone marrow and adipose tissue
    A T Mehlhorn
    Department of Orthopaedic and Trauma Surgery, University Medical Center, Albert Ludwigs University, Freiburg, Germany
    Tissue Eng 12:2853-62. 2006
    ..These findings may direct the development of a cell-specific culture environment either to prevent hypertrophy in BMSCs or to promote chondrogenic maturation in ADASCs...
  8. ncbi request reprint Survival of human mesenchymal stromal cells from bone marrow and adipose tissue after xenogenic transplantation in immunocompetent mice
    P Niemeyer
    Department of Orthopedic Surgery and Traumatology, Freiburg University Hospital, Freiburg, Germany
    Cytotherapy 10:784-95. 2008
    ..The purpose of the current paper was to evaluate the survival of undifferentiated and osteogenically induced human MSC from different origins after transplantation in immunocompetent mice...
  9. ncbi request reprint Stimulation of chondrocytes in vitro by gene transfer with plasmids coding for epidermal growth factor (hEGF) and basic fibroblast growth factor (bFGF)
    H Schmal
    Department of Orthopedics and Traumatology, University of Freiburg Medical Center, Freiburg, Germany
    Cytotherapy 7:292-300. 2005
    ..Temporary in vitro gene transfer of the growth factors hEGF and bFGF provides a method to stimulate chondrocyte proliferation and induces signs of dedifferentiation, which would limit a reasonable clinical application...
  10. doi request reprint Percutaneous iliosacral screw insertion: malpositioning and revision rate of screws with regards to application technique (navigated vs. Conventional)
    J Zwingmann
    Department of Orthopaedic and Trauma Surgery, University of Freiburg Medical Center, Freiburg, Germany
    J Trauma 69:1501-6. 2010
    ....
  11. ncbi request reprint Regulative mechanisms of chondrocyte adhesion
    Hagen Schmal
    Department of Orthopedics and Traumatology, University of Freiburg Medical Center, Freiburg, Germany
    Tissue Eng 12:741-50. 2006
    ..Matrix design in cartilage engineering must meet the biological demands of amplified cells, because adhesion of chondrocytes depends on their differentiation status and is regulated by bFGF...