Jakob Matschke

Summary

Affiliation: University Medical Center Hamburg-Eppendorf
Country: Germany

Publications

  1. pmc Shaken baby syndrome: a common variant of non-accidental head injury in infants
    Jakob Matschke
    Forensische Neuropathologie, Institut für Neuropathologie, Universitatsklinikum Hamburg Eppendorf, Hamburg
    Dtsch Arztebl Int 106:211-7. 2009
  2. ncbi request reprint Fatal ischemic stroke due to dissecting aneurysm of the intracranial arteries presenting as sudden unexpected death in childhood
    Jakob Matschke
    Forensic Neuropathology Unit, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Am J Forensic Med Pathol 31:364-9. 2010
  3. doi request reprint Nonaccidental head injury is the most common cause of subdural bleeding in infants <1 year of age
    Jakob Matschke
    Forensic Neuropathology, University Medical Center Hamburg Eppendorf, Martinistrasse 52, D 20246 Hamburg, Germany
    Pediatrics 124:1587-94. 2009
  4. doi request reprint Ocular pathology in shaken baby syndrome and other forms of infantile non-accidental head injury
    Jakob Matschke
    Forensic Neuropathology, University Medical Centre Hamburg Eppendorf, Hamburg, Germany
    Int J Legal Med 123:189-97. 2009
  5. doi request reprint Frequent genetic alterations in EGFR- and HER2-driven pathways in breast cancer brain metastases
    Ina Hohensee
    Department of Tumor Biology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Am J Pathol 183:83-95. 2013
  6. ncbi request reprint Intracranial arteriovenous malformations presenting as sudden unexpected death: a report of 3 cases and review of the literature
    Jakob Matschke
    Institute of Neuropathology, University Medical Center Hamburg, Hamburg, Germany
    Am J Forensic Med Pathol 28:173-6. 2007
  7. doi request reprint Plasma levels of neuron specific enolase quantify the extent of neuronal injury in murine models of ischemic stroke and multiple sclerosis
    Mathias Gelderblom
    Department of Neurology, University Medical Center Hamburg Eppendorf, Martinistr 52, 20246 Hamburg, Germany
    Neurobiol Dis 59:177-82. 2013
  8. doi request reprint Deposition of hyperphosphorylated tau in cerebellum of PS1 E280A Alzheimer's disease
    Diego Sepulveda-Falla
    Institute of Neuropathology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Brain Pathol 21:452-63. 2011
  9. doi request reprint Blister-like aneurysms--a diagnostic and therapeutic challenge
    Jan Regelsberger
    Universitatsklinikum Hamburg Eppendorf, Neurochirurgische Klinik, Hamburg, Germany
    Neurosurg Rev 34:409-16. 2011
  10. doi request reprint Autoantibodies against beta-amyloid are common in Alzheimer's disease and help control plaque burden
    Alexander Kellner
    Institute of Neuropathology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Ann Neurol 65:24-31. 2009

Collaborators

Detail Information

Publications14

  1. pmc Shaken baby syndrome: a common variant of non-accidental head injury in infants
    Jakob Matschke
    Forensische Neuropathologie, Institut für Neuropathologie, Universitatsklinikum Hamburg Eppendorf, Hamburg
    Dtsch Arztebl Int 106:211-7. 2009
    ..Abuse of infants often leaves few external signs of injury and therefore merits special diligence, especially in the case of non-accidental head injury, which has high morbidity and mortality...
  2. ncbi request reprint Fatal ischemic stroke due to dissecting aneurysm of the intracranial arteries presenting as sudden unexpected death in childhood
    Jakob Matschke
    Forensic Neuropathology Unit, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Am J Forensic Med Pathol 31:364-9. 2010
    ..Outcome is poor, with more than 20% of patients dying. We report 4 cases of sudden unexpected death due to arterial ischemic stroke after cerebral arterial dissection in childhood and present a review of the literature...
  3. doi request reprint Nonaccidental head injury is the most common cause of subdural bleeding in infants <1 year of age
    Jakob Matschke
    Forensic Neuropathology, University Medical Center Hamburg Eppendorf, Martinistrasse 52, D 20246 Hamburg, Germany
    Pediatrics 124:1587-94. 2009
    ..We analyzed a large series of infants' autopsies for the presence and causes of SDB, which should be a common event according to the unified hypothesis...
  4. doi request reprint Ocular pathology in shaken baby syndrome and other forms of infantile non-accidental head injury
    Jakob Matschke
    Forensic Neuropathology, University Medical Centre Hamburg Eppendorf, Hamburg, Germany
    Int J Legal Med 123:189-97. 2009
    ..This review summarizes the present knowledge of ocular pathology in inflicted infantile neurotrauma, focusing strongly on SBS. Furthermore, a review of the most recent literature on the subject is given...
  5. doi request reprint Frequent genetic alterations in EGFR- and HER2-driven pathways in breast cancer brain metastases
    Ina Hohensee
    Department of Tumor Biology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Am J Pathol 183:83-95. 2013
    ..In contrast, none of these pathways was associated with an increased risk of bone metastasis. These findings highlight the importance of both pathways as possible targets in the treatment of brain metastases in breast cancer...
  6. ncbi request reprint Intracranial arteriovenous malformations presenting as sudden unexpected death: a report of 3 cases and review of the literature
    Jakob Matschke
    Institute of Neuropathology, University Medical Center Hamburg, Hamburg, Germany
    Am J Forensic Med Pathol 28:173-6. 2007
    ..We present 3 cases of sudden death due to hemorrhage of AVM and discuss the literature and the differential diagnosis in cases of sudden death due to intracranial hemorrhage...
  7. doi request reprint Plasma levels of neuron specific enolase quantify the extent of neuronal injury in murine models of ischemic stroke and multiple sclerosis
    Mathias Gelderblom
    Department of Neurology, University Medical Center Hamburg Eppendorf, Martinistr 52, 20246 Hamburg, Germany
    Neurobiol Dis 59:177-82. 2013
    ..We aimed at validating a plasma biomarker for neuronal damage that can be used in acute and chronic models of neurological diseases...
  8. doi request reprint Deposition of hyperphosphorylated tau in cerebellum of PS1 E280A Alzheimer's disease
    Diego Sepulveda-Falla
    Institute of Neuropathology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Brain Pathol 21:452-63. 2011
    ..The presence of pTau in cerebellum in PS1-E280A underscores the relevance of cerebellar involvement in AD and might be correlated to clinical phenotype...
  9. doi request reprint Blister-like aneurysms--a diagnostic and therapeutic challenge
    Jan Regelsberger
    Universitatsklinikum Hamburg Eppendorf, Neurochirurgische Klinik, Hamburg, Germany
    Neurosurg Rev 34:409-16. 2011
    ..If endovascular treatment is not promising, wrapping and revascularization techniques come true to still be an important part of the neurosurgeons toolbox for reconstructing a vessel lumen and preserving a sufficient cerebral blood flow...
  10. doi request reprint Autoantibodies against beta-amyloid are common in Alzheimer's disease and help control plaque burden
    Alexander Kellner
    Institute of Neuropathology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Ann Neurol 65:24-31. 2009
    ..Here, we investigate whether naturally occurring autoantibodies to beta-amyloid contribute to beta-amyloid plaque removal in nonimmunized AD patients...
  11. ncbi request reprint Sudden death due to central alveolar hypoventilation syndrome (Ondine's curse) in a 39-year-old woman with heterotopia of the inferior olive
    Jakob Matschke
    Institute of Neuropathology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Am J Forensic Med Pathol 28:141-4. 2007
    ..Mechanisms in the present case are discussed and a review of similar cases published so far is given. The necessity of sound investigation, including neuropathologic studies in cases of sudden unexplained death, is underlined...
  12. ncbi request reprint Understanding the natural variability of prion diseases
    Markus Geissen
    Institute of Neuropathology, Universitatsklinikum Hamburg Eppendorf, 20246 Hamburg, Germany
    Vaccine 25:5631-6. 2007
    ..Current classification systems are based on the assessment of clinical presentation, genetic investigations, neuropathological findings and biochemical analysis of PrP(Sc)...
  13. ncbi request reprint Sudden unexpected death due to undiagnosed glioblastoma: report of three cases and review of the literature
    Jakob Matschke
    Institute of Neuropathology, University Medical Centre, Martinistrasse 52, 20246 Hamburg, Germany
    Int J Legal Med 119:280-4. 2005
    ....
  14. ncbi request reprint Sudden death in a 35-year-old man with occult malformation of the brain and aseptic meningitis
    Jakob Matschke
    Institute of Neuropathology, University Hospital of Hamburg Eppendorf, Hamburg, Germany
    Am J Forensic Med Pathol 24:83-6. 2003
    ..The morphologic findings of this case are presented, and the probable mechanisms of death are discussed...