Matthias Maschke

Summary

Affiliation: University of Essen
Country: Germany

Publications

  1. ncbi request reprint Dysfunction of the basal ganglia, but not the cerebellum, impairs kinaesthesia
    Matthias Maschke
    Sensorimotor Control Laboratory, University of Minnesota, Minneapolis, USA
    Brain 126:2312-22. 2003
  2. ncbi request reprint Depth perception in cerebellar and basal ganglia disease
    Matthias Maschke
    Department of Neurology, University of Duisburg Essen, Hufelandstrasse 55, 45122, Essen, Germany
    Exp Brain Res 175:165-76. 2006
  3. ncbi request reprint Update on neuroimaging in infectious central nervous system disease
    Matthias Maschke
    Department of Neurology and Department of Radiology, University of Duisburg Essen, Essen, Germany
    Curr Opin Neurol 17:475-80. 2004
  4. ncbi request reprint Vermal atrophy of alcoholics correlate with serum thiamine levels but not with dentate iron concentrations as estimated by MRI
    Matthias Maschke
    Department of Neurology, University Duisburg Essen, Hufelandstr 55, 45122 Essen, Germany
    J Neurol 252:704-11. 2005
  5. ncbi request reprint Differences in trace and delay visuomotor associative learning in cerebellar patients
    Matthias Maschke
    Department of Neurology, University of Essen, Hufelandstrasse 55, 45122 Essen, Germany
    Exp Brain Res 147:538-48. 2002
  6. pmc The effect of subthalamic nucleus stimulation on kinaesthesia in Parkinson's disease
    M Maschke
    Sensorimotor Control Laboratory, Division of Kinesiology, University of Minnesota, Minneapolis, MN, USA
    J Neurol Neurosurg Psychiatry 76:569-71. 2005
  7. ncbi request reprint Limb flexion reflex-related areas in human cerebellum
    Matthias Maschke
    Department of Nuclear Medicine, University of Essen, Hufelandstr 55, 45122 Essen, Germany
    Neuroreport 13:2325-30. 2002
  8. ncbi request reprint Hereditary cerebellar ataxia progressively impairs force adaptation during goal-directed arm movements
    Matthias Maschke
    Sensorimotor Control Laboratory, University of Minnesota, Minneapolis, Minnesota 55455, USA
    J Neurophysiol 91:230-8. 2004
  9. ncbi request reprint [Multiple sclerosis. Current aspects of the disease and treatment]
    Matthias Maschke
    Klinik und Poliklinik fur Neurologie, Universitätsklinik Essen, Universitat Duisburg Essen, Hufelandstr 55, 45122 Essen
    Med Monatsschr Pharm 26:404-8; quiz 409-10. 2003
  10. ncbi request reprint Age-related changes of the dentate nuclei in normal adults as revealed by 3D fast low angle shot (FLASH) echo sequence magnetic resonance imaging
    Matthias Maschke
    Department of Neurology, University of Duisburg Essen, Hufelandstr 55, 45122 Essen, Germany
    J Neurol 251:740-6. 2004

Detail Information

Publications81

  1. ncbi request reprint Dysfunction of the basal ganglia, but not the cerebellum, impairs kinaesthesia
    Matthias Maschke
    Sensorimotor Control Laboratory, University of Minnesota, Minneapolis, USA
    Brain 126:2312-22. 2003
    ..These results imply that an intact cerebro-basal ganglia loop is essential for awareness of limb position and suggest a selective role of the basal ganglia but not the cerebellum in kinaesthesia...
  2. ncbi request reprint Depth perception in cerebellar and basal ganglia disease
    Matthias Maschke
    Department of Neurology, University of Duisburg Essen, Hufelandstrasse 55, 45122, Essen, Germany
    Exp Brain Res 175:165-76. 2006
    ....
  3. ncbi request reprint Update on neuroimaging in infectious central nervous system disease
    Matthias Maschke
    Department of Neurology and Department of Radiology, University of Duisburg Essen, Essen, Germany
    Curr Opin Neurol 17:475-80. 2004
    ..It focuses on imaging of viral encephalitis, including that caused by exotic and emerging viruses, and on imaging in immunodeficient patients...
  4. ncbi request reprint Vermal atrophy of alcoholics correlate with serum thiamine levels but not with dentate iron concentrations as estimated by MRI
    Matthias Maschke
    Department of Neurology, University Duisburg Essen, Hufelandstr 55, 45122 Essen, Germany
    J Neurol 252:704-11. 2005
    ..344, p = 0.028). These results support the view that thiamine deficiency rather than direct neurotoxic effects of alcohol is the main causative factor for the development of alcoholic cerebellar degeneration...
  5. ncbi request reprint Differences in trace and delay visuomotor associative learning in cerebellar patients
    Matthias Maschke
    Department of Neurology, University of Essen, Hufelandstrasse 55, 45122 Essen, Germany
    Exp Brain Res 147:538-48. 2002
    ..The lack of a better performance in the trace-condition compared to the delay-condition in cerebellar patients suggests deficits in learning the stimulus-response association...
  6. pmc The effect of subthalamic nucleus stimulation on kinaesthesia in Parkinson's disease
    M Maschke
    Sensorimotor Control Laboratory, Division of Kinesiology, University of Minnesota, Minneapolis, MN, USA
    J Neurol Neurosurg Psychiatry 76:569-71. 2005
    ..Parkinson's disease is accompanied by deficits in passive motion and limb position sense...
  7. ncbi request reprint Limb flexion reflex-related areas in human cerebellum
    Matthias Maschke
    Department of Nuclear Medicine, University of Essen, Hufelandstr 55, 45122 Essen, Germany
    Neuroreport 13:2325-30. 2002
    ..Limb flexion reflex areas probably reflect efferent reflex modulation as well as sensory inputs from the stimulus itself and/or the reflex response...
  8. ncbi request reprint Hereditary cerebellar ataxia progressively impairs force adaptation during goal-directed arm movements
    Matthias Maschke
    Sensorimotor Control Laboratory, University of Minnesota, Minneapolis, Minnesota 55455, USA
    J Neurophysiol 91:230-8. 2004
    ..The failure to generalize learning suggests that cerebellar degeneration prevents the formation of an internal representation of the limb dynamics...
  9. ncbi request reprint [Multiple sclerosis. Current aspects of the disease and treatment]
    Matthias Maschke
    Klinik und Poliklinik fur Neurologie, Universitätsklinik Essen, Universitat Duisburg Essen, Hufelandstr 55, 45122 Essen
    Med Monatsschr Pharm 26:404-8; quiz 409-10. 2003
  10. ncbi request reprint Age-related changes of the dentate nuclei in normal adults as revealed by 3D fast low angle shot (FLASH) echo sequence magnetic resonance imaging
    Matthias Maschke
    Department of Neurology, University of Duisburg Essen, Hufelandstr 55, 45122 Essen, Germany
    J Neurol 251:740-6. 2004
    ..These age-dependent changes have to be taken into account in interpretation of disease related MR changes of cerebellar nuclei in patients with degenerative or acquired cerebellar ataxia...
  11. ncbi request reprint CNS manifestations of cytomegalovirus infections: diagnosis and treatment
    Matthias Maschke
    Department of Neurology, University Clinic of Essen, Germany
    CNS Drugs 16:303-15. 2002
    ..Despite therapy, the prognosis for long-term survival is very poor, especially in patients with AIDS...
  12. ncbi request reprint A possible role of the human cerebellum in conditioning of the jaw-opening reflex
    M Maschke
    Department of Neurology, University of Essen, Hufelandstrasse 55, 45122, Essen, Germany
    Neurosci Lett 285:213-7. 2000
    ..Thus, the intermediate cerebellum appears to be involved in classical conditioning of the jaw-opening reflex in humans...
  13. pmc Fear conditioned potentiation of the acoustic blink reflex in patients with cerebellar lesions
    M Maschke
    Department of Neurology, University of Essen, Germany
    J Neurol Neurosurg Psychiatry 68:358-64. 2000
    ..To investigate whether the human cerebellum takes part in fear conditioned potentiation of the acoustic blink reflex...
  14. ncbi request reprint Perception of heaviness in Parkinson's disease
    Matthias Maschke
    Sensorimotor Control Laboratory, University of Minnesota, Minneapolis, USA
    Mov Disord 21:1013-8. 2006
    ..These findings underline the growing evidence that proprioceptive and possibly haptic dysfunction is a common feature of PD...
  15. pmc Incidence and prevalence of neurological disorders associated with HIV since the introduction of highly active antiretroviral therapy (HAART)
    M Maschke
    Department of Neurology, University Clinic Essen, Hufelandstrasse 55, 45122 Essen, Germany
    J Neurol Neurosurg Psychiatry 69:376-80. 2000
    ....
  16. pmc Fear conditioned changes of heart rate in patients with medial cerebellar lesions
    M Maschke
    Department of Neurology, University of Essen, Hufelandstrasse 55, 45122 Essen, Germany
    J Neurol Neurosurg Psychiatry 72:116-8. 2002
    ..However, there were no significant fear conditioned changes in electrodermal responses in either group. In summary, the medial cerebellum seems to be involved in fear-conditioned bradycardia in humans...
  17. ncbi request reprint Involvement of the human medial cerebellum in long-term habituation of the acoustic startle response
    M Maschke
    Department of Neurology, University of Essen, Germany
    Exp Brain Res 133:359-67. 2000
    ..The present findings suggest that the medial cerebellum is involved in long-term habituation of the blink component of the startle response in humans...
  18. doi request reprint Recovery of upper limb function after cerebellar stroke: lesion symptom mapping and arm kinematics
    Jurgen Konczak
    Human Sensorimotor Control Laboratory, University of Minnesota, Minneapolis, MN 55455, USA
    Stroke 41:2191-200. 2010
    ..This study provides a comprehensive assessment of how lesion site and arm dysfunction are associated in the acute stage and outlines the course of upper limb motor recovery for the first 4 months after the infarction...
  19. ncbi request reprint Timing of conditioned eyeblink responses is impaired in cerebellar patients
    Marcus Gerwig
    Department of Neurology, University of Duisburg Essen, D 45147 Essen, Germany
    J Neurosci 25:3919-31. 2005
    ..Extracerebellar premotoneuronal disinhibition, however, is another possible explanation for changes in CR timing...
  20. ncbi request reprint Habituation of the auditory startle response in cervical dystonia and Parkinson's disease
    Norman Putzki
    Department of Neurology, University of Duisburg Essen, Essen, Germany
    Eur Neurol 59:172-8. 2008
    ..Normal latencies and sequence activation indicate intact neural pathways mediating the ASR in FD. Impaired habituation of the ASR points towards a reduced inhibition of acoustic stimuli in FD...
  21. doi request reprint Cytokine levels in CSF and neuropsychological performance in HIV patients
    Thorsten Nolting
    Department of Neurology, Medical School, Heinrich Heine University, Duesseldorf, Germany
    J Neurovirol 18:157-61. 2012
    ..Therapeutic strategies to ameliorate a negative impact of an altered cytokine milieu may aid in slowing the evolution of neurocognitive dysfunction...
  22. ncbi request reprint Functional recovery and rehabilitation of postural impairment and gait ataxia in patients with acute cerebellar stroke
    Uta Bultmann
    Department of Neurology, University of Duisburg Essen, Hufelandstr 55, 45122 Essen, Germany
    Gait Posture 39:563-9. 2014
    ..Treadmill training did not show significant effects. Future studies are needed to investigate whether intensive coordinative training is of benefit in patients with cerebellar stroke. ..
  23. ncbi request reprint Cerebellar representation of the eyeblink response as revealed by PET
    Matthias Maschke
    Department of Neurology, University of Essen, Hufelandstr 55, 45122 Essen, Germany
    Neuroreport 14:1371-4. 2003
    ..In conclusion, vermal lobule VI extending to ipsilateral paravermal areas appears to be involved in control of the unconditioned eyeblink response...
  24. ncbi request reprint Involvement of the human cerebellum in fear-conditioned potentiation of the acoustic startle response: a PET study
    Markus Frings
    Department of Neurology, University of Essen, Hufelandstrasse 55, 45122 Essen, Germany
    Neuroreport 13:1275-8. 2002
    ..Subtraction of condition L from LT, as a measure of fear-conditioned potentiation, revealed an increase of rCBF in the medial cerebellum. Different parts of the cerebellum appear to be involved in this form of motor associative learning...
  25. ncbi request reprint Involvement of the human cerebellum in short-term and long-term habituation of the acoustic startle response: a serial PET study
    Markus Frings
    Department of Neurology, University of Duisburg Essen, Hufelandstrasse 55, D 45122 Essen, Germany
    Clin Neurophysiol 117:1290-300. 2006
    ..The present study sought to distinguish which areas of the human cerebellum and brain-stem are involved in short-term habituation (STH) and long-term habituation (LTH) of the acoustic startle response...
  26. ncbi request reprint Transcranial sonography of the third ventricle and cognitive dysfunction in HIV patients
    Ozgur Yaldizli
    Department of Neurology, University of Duisburg Essen, Hufelandstr 55, Essen 45122, Germany
    J Neurol 253:1185-8. 2006
    ..Previous magnetic resonance imaging (MRI) studies showed a correlation between brain atrophy, enlargement of the ventricles and cognitive impairment in HIV patients...
  27. doi request reprint Aphasia and neglect are uncommon in cerebellar disease: negative findings in a prospective study in acute cerebellar stroke
    Benedikt Frank
    Department of Neurology, University of Duisburg Essen, Hufelandstr 55, 45122, Essen, Germany
    Cerebellum 9:556-66. 2010
    ..This does not exclude, however, that abnormalities may be present in more sophisticated testing of language and visuospatial functions...
  28. ncbi request reprint Eyeblink-related areas in human cerebellum as shown by fMRI
    Albena Dimitrova
    Department of Neurology, University of Essen, Hufelandstrasse 55, D 45122 Essen, Germany
    Hum Brain Mapp 17:100-15. 2002
    ..These eyeblink-related areas agree with trigeminal projection areas and blink reflex control areas shown in previous animal studies...
  29. ncbi request reprint The role of the human cerebellum in short- and long-term habituation of postural responses
    Achim Schwabe
    Department of Neurology, University of Essen, Hufelandstrasse 55, 45122 Essen, Germany
    Gait Posture 19:16-23. 2004
    ..The amount of changes within and across days did not significantly differ between groups. The present findings suggest that changes of postural response size to repeated perturbations do not depend upon the integrity of the cerebellum...
  30. ncbi request reprint Cerebellar activation during leg withdrawal reflex conditioning: an fMRI study
    Albena Dimitrova
    Department of Neurology, University of Duisburg Essen, Hufelandstrasse 55, 45122 Essen, Germany
    Clin Neurophysiol 115:849-57. 2004
    ..Because of the aversive nature of the unconditioned stimulus effects of accompanying fear conditioning were expected...
  31. ncbi request reprint Reliability and validity of ICARS in focal cerebellar lesions
    Beate Schoch
    Department of Neurosurgery, University of Duisburg Essen, Essen, Germany
    Mov Disord 22:2162-9. 2007
    ..Validity of subscores however is good in focal, but not in degenerative disorders...
  32. ncbi request reprint Degree of cerebellar ataxia correlates with three-dimensional mri-based cerebellar volume in pure cerebellar degeneration
    Stefanie Richter
    Department of Neurology, University of Duisburg Essen, Essen, Germany
    Eur Neurol 54:23-7. 2005
    ..The results suggest that the degree of cerebellar atrophy in pure cerebellar degenerative disorders is accompanied by comparable functional impairment (i.e. degree of cerebellar ataxia)...
  33. ncbi request reprint Acquisition of simple auditory and visual sequences in cerebellar patients
    Markus Frings
    Department of Neurology, University of Duisburg Essen, Essen, Germany
    Cerebellum 5:206-11. 2006
    ..Differences in findings between previous and the present study may be explained by differences in motor demands and the explicit nature of the tasks...
  34. ncbi request reprint Correlation of epidermal nerve fiber density with pain-related evoked potentials in HIV neuropathy
    Mark Obermann
    Department of Neurology, University of Duisburg Essen, Hufelandstr 55, 45122 Essen, Germany
    Pain 138:79-86. 2008
    ..The method of pain-related evoked potential conduction appears to be a sensitive, fast, non-invasive technique for the detection of small-fiber neuropathy and may prove to become a valuable diagnostic asset...
  35. ncbi request reprint Sensory disinhibition on passive movement in cervical dystonia
    Mark Obermann
    Department of Neurology, University of Duisburg Essen, Essen, Germany
    Mov Disord 25:2627-33. 2010
    ..The observed sensory overactivation suggests a general disinhibition of the somatosensory system in CD as it was not limited to the motor-system or the direct neuronal representation of the affected dystonic musculature alone...
  36. doi request reprint Proprioception and motor control in Parkinson's disease
    Jurgen Konczak
    School of Kinesiology, University of Minnesota, Minneapolis, MN 55455, USA
    J Mot Behav 41:543-52. 2009
    ..The authors conclude that a failure to evaluate and to map proprioceptive information onto voluntary and reflexive motor commands is an integral part of the observed motor symptoms in PD...
  37. ncbi request reprint Pain related potentials by electrical stimulation of skin for detection of small-fiber neuropathy in HIV
    Zaza Katsarava
    Department of Neurology, University of Essen, Hufelandstr 55, 45122, Essen, Germany, and Institute of Neurology, The National Hospital for Neurology and Neurosurgery, London, UK
    J Neurol 253:1581-4. 2006
    ..SNC testing revealed a neuropathy in only 31%, whereas PREP was abnormal in 74% of symptomatic patients. This result hints that PREP is more sensitive in the detection of HIV-associated small fiber neuropathy than standard neurography...
  38. ncbi request reprint Morphometric changes of sensorimotor structures in focal dystonia
    Mark Obermann
    Department of Neurology, University of Duisburg Essen, Essen, Germany
    Mov Disord 22:1117-23. 2007
    ..They also demonstrate structural similarities of the investigated focal dystonias, possibly reflecting a shared common pathophysiological origin...
  39. ncbi request reprint Kinesthesia is impaired in focal dystonia
    Norman Putzki
    Department of Neurology, University of Duisburg Essen, Essen, Germany
    Mov Disord 21:754-60. 2006
    ..Results of the present study point to impaired kinesthesia in FD. Defective sensory processing could be involved in the pathophysiology of the disease and may influence dystonic contractions...
  40. doi request reprint Neuroimaging of infections of the central nervous system
    Oliver Kastrup
    Department of Neurology, University Duisburg Essen, Hufelandstrasse 55, Essen, Germany
    Semin Neurol 28:511-22. 2008
    ..In patients with viral encephalitis, DWI allows earlier lesion detection. MRI has revolutionized the rapid diagnosis of spinal abscess...
  41. ncbi request reprint Trace eyeblink conditioning in human subjects with cerebellar lesions
    M Gerwig
    Department of Neurology, University of Duisburg Essen, Hufelandstrasse 55, 45147, Essen, Germany
    Exp Brain Res 170:7-21. 2006
    ....
  42. ncbi request reprint Carotid intima-media thickness in HIV-infected individuals: relationship of premature atherosclerosis to neuropsychological deficits?
    Ozgur Yaldizli
    Department of Neurology, University of Duisburg Essen, Germany
    Eur Neurol 55:166-71. 2006
    ..Therefore, the objective of this study was to investigate the correlation between IMT and neuropsychological deficits in HIV patients...
  43. ncbi request reprint Adaptive motor behavior of cerebellar patients during exposure to unfamiliar external forces
    Stefanie Richter
    University of Düsseldorf and University of Essen, Germany
    J Mot Behav 36:28-38. 2004
    ..Force adaptation may have been preserved because single-joint movements were performed, whereas the negative viscous force alone and no interaction forces had to be compensated...
  44. ncbi request reprint Intravenous thrombolysis in German stroke units before and after regulatory approval of recombinant tissue plasminogen activator
    C Weimar
    Department of Neurology, University of Duisburg Essen, Essen, Germany
    Cerebrovasc Dis 22:429-31. 2006
    ..Intravenous thrombolysis with recombinant tissue plasminogen activator (rt-PA) within 3 h after onset of focal cerebral ischemia was approved in Germany in August 2000...
  45. ncbi request reprint Efficacy of natalizumab in second line therapy of relapsing-remitting multiple sclerosis: results from a multi-center study in German speaking countries
    N Putzki
    Department of Neurology, University Clinic Essen, University of Duisburg Essen, Germany
    Eur J Neurol 17:31-7. 2010
    ..The pivotal trials were not conducted to investigate natalizumab monotherapy in this patient population...
  46. pmc Effects of aspirin plus extended-release dipyridamole versus clopidogrel and telmisartan on disability and cognitive function after recurrent stroke in patients with ischaemic stroke in the Prevention Regimen for Effectively Avoiding Second Strokes (PRoFE
    Hans Christoph Diener
    Department of Neurology, University of Duisburg Essen, Essen, Germany
    Lancet Neurol 7:875-84. 2008
    ..The putative neuroprotective effects of antiplatelet compounds and the angiotensin II receptor antagonist telmisartan were investigated in the Prevention Regimen for Effectively Avoiding Second Strokes (PRoFESS) trial...
  47. ncbi request reprint Prevalence of trigeminal autonomic symptoms in migraine: a population-based study
    M Obermann
    Department of Neurology, University of Duisburg Essen, Essen, Germany
    Cephalalgia 27:504-9. 2007
    ..Migraine patients with accompanying autonomic symptoms seem to experience their pain more unilateral and more severe than non-UA patients...
  48. ncbi request reprint Posterior reversible encephalopathy syndrome due to severe hypercalcemia
    O Kastrup
    Neurologische Universitatsklinik, Hufelandstr 55, 45122 Essen, Germany
    J Neurol 249:1563-6. 2002
    ..We report two cases of PRES in normotensive patients with severe hypercalcemia as the only identifiable cause. Possible pathophysiological mechanisms are discussed...
  49. ncbi request reprint Progressive multifocal leukoencephalopathy limited to the brain stem
    O Kastrup
    Neurologische Universitatsklinik, University of Essen, Germany
    Neuroradiology 44:227-9. 2002
    ..This case was also notable because of the rapid progression despite improved immune status with antiretroviral therapy...
  50. ncbi request reprint Wernicke's encephalopathy: unusual contrast enhancement revealed by magnetic resonance imaging
    Ilker Kavuk
    Department of Neurology, University of Essen, Hufelandstrasse 55, D 45122 Essen, Germany
    Eur J Med Res 8:492-4. 2003
    ..As a consequence from the guideline for managing Wernicke's encephalopathy by the Royal College of Physicians early B-vitamin treatment in suspected is recommended cases...
  51. ncbi request reprint Amplitude changes of unconditioned eyeblink responses in patients with cerebellar lesions
    M Gerwig
    Department of Neurology, University of Duisburg Essen, Hufelandstr 55, 45147, Essen, Germany
    Exp Brain Res 155:341-51. 2004
    ..These areas partly overlap with areas known to be critical in eyeblink conditioning...
  52. ncbi request reprint Use of sequence information in associative learning in control subjects and cerebellar patients
    D Timmann
    Department of Neurology, University of Duisburg Essen, Germany
    Cerebellum 3:75-82. 2004
    ..Results suggest that impaired sequencing of sensory stimuli may contribute to disorders in visuomotor associative learning in cerebellar patients...
  53. ncbi request reprint Presumed pharmacologically induced change from upbeat- to downbeat nystagmus in a patient with Wernicke's encephalopathy
    O Kastrup
    Department of Neurology, University of Essen, Hufelandstr 55, 45122 Essen, Germany
    Clin Neurol Neurosurg 107:70-2. 2004
    ..The case was also notable for the finding of positive oligoclonal bands in the CSF. The underlying pathophysiological mechanisms and a possible effect of baclofen treatment are discussed...
  54. ncbi request reprint Eyeblink conditioning in patients with hereditary ataxia: a one-year follow-up study
    D Timmann
    Department of Neurology, University of Duisburg Essen, Hufelandstrasse 55, 45122, Essen, Germany
    Exp Brain Res 162:332-45. 2005
    ..In other heredoataxias (such as SCA3 and FRDA), extracerebellar involvement not assessed by ICARS likely contributes to eyeblink conditioning abnormalities...
  55. ncbi request reprint Motor deficits cannot explain impaired cognitive associative learning in cerebellar patients
    Dagmar Timmann
    Department of Neurology, University of Essen, Hufelandstrasse 55, D 45122 Essen, Germany
    Neuropsychologia 40:788-800. 2002
    ..However, this deficit was independent of the motor difficulty of the task. The cerebellum seems to contribute to motor-independent processes, which are generally involved in associative learning...
  56. ncbi request reprint Hashimoto encephalopathy and neuralgic amyotrophy--causal link or chance association?
    O Kastrup
    Department of Neurology, University Duisburg Essen, Essen, Germany
    Eur Neurol 53:98-9. 2005
  57. ncbi request reprint Cavernous malformation with hemorrhage of the conus medullaris and progressive sensory loss
    M Obermann
    Department of Neurology, University Duisburg Essen, Germany
    Clin Neuropathol 25:95-7. 2006
    ..It is essential to achieve complete removal during the first operation to avoid any residues that may lead to further bleeding...
  58. ncbi request reprint Evolution of purely infratentorial PML under HAART--negative outcome under rapid immune reconstitution
    O Kastrup
    Department of Neurology, University of Duisburg Essen, Hufelandstr 55, 45122 Essen, Germany
    Clin Neurol Neurosurg 107:509-13. 2005
    ..Possible underlying immunological mechanisms are discussed...
  59. ncbi request reprint Basal ganglia infarction mimicking glioblastoma
    O Yaldizli
    Department of Neurology, University of Essen, Hufelandstr 55, D 45122 Essen, Germany
    Eur J Med Res 10:400-1. 2005
    ..Our case demonstrates that brain infarctions can mimick glioblastoma in taking cystic appearance and contrast enhancement. Stereotactic biopsy would have been a precipitated invasive procedure in this case...
  60. ncbi request reprint MRI of intracranial toxoplasmosis after bone marrow transplantation
    U Dietrich
    Department of Neuroradiology, University Hospital, Hufelandstrasse 55, 45122 Essen, Germany
    Neuroradiology 42:14-8. 2000
    ..In patients with a low leukocyte count and/or high doses of immunosuppressive therapy, typical contrast enhancement may be absent...
  61. ncbi request reprint Children and adolescents with chronic cerebellar lesions show no clinically relevant signs of aphasia or neglect
    S Richter
    Department of Neurology, University of Duisburg Essen, Germany
    J Neurophysiol 94:4108-20. 2005
    ..In sum, chronic focal cerebellar lesions acquired in childhood or youth do not result in persistent language disorders or clinically significant signs of spatial neglect or extinction...
  62. ncbi request reprint Strategies in detection of the primary tumour in anti-Yo associated paraneoplastic cerebellar degeneration
    Markus Frings
    Dept of Neurology, University of Duisburg Essen, Hufelandstrasse 55, 45122 Essen, Germany
    J Neurol 252:197-201. 2005
    ..It may help in guidance of needle biopsy or to optimise the results of deliberate surgery and it provides whole-body tumour staging in a single session with higher diagnostic accuracy than PET alone...
  63. ncbi request reprint Behavioral and affective changes in children and adolescents with chronic cerebellar lesions
    Stefanie Richter
    Department of Neurology, University of Duisburg Essen, Hufelandstr, 55 45122 Essen, Germany
    Neurosci Lett 381:102-7. 2005
    ..In conclusion, minor behavioral and affective changes were present in a subset of children with chronic vermal lesions...
  64. ncbi request reprint Effect of functional NMDA-antagonist flupirtine on automatic postural responses in Parkinson's disease
    Norman Putzki
    Department of Neurology, University of Essen, Hufelandstrasse 55, Germany
    J Neurol 249:824-8. 2002
    ..No improvement in the UPDRS motor subscale was observed. As no beneficial effect on the clinical presentation and no effect on postural responses could be demonstrated, flupirtine does not seem to be a therapeutic option in PD...
  65. ncbi request reprint Comparison of eyeblink conditioning in patients with superior and posterior inferior cerebellar lesions
    M Gerwig
    Department of Neurology, University of Essen, Department of Neurology, Fachklinik Rhein Ruhr, Essen, Germany
    Brain 126:71-94. 2003
    ..To summarize, unilateral cortical lesions of the superior cerebellum appear to be sufficient to reduce eyeblink conditioning in humans significantly...
  66. ncbi request reprint The human cerebellum contributes to motor, emotional and cognitive associative learning. A review
    D Timmann
    Department of Neurology, University of Duisburg Essen, Hufelandstrasse 55, Essen, Germany
    Cortex 46:845-57. 2010
    ..The overall task of the cerebellum may be the ability to provide correct predictions about the relationship between sensory stimuli...
  67. doi request reprint Measurement of soluble inflammatory mediators in cerebrospinal fluid of human immunodeficiency virus-positive patients at distinct stages of infection by solid-phase protein array
    Thorsten Nolting
    Department of Neurology, Heinrich Heine University, Duesseldorf, Germany
    J Neurovirol 15:390-400. 2009
    ..Pending further validation on a larger number of patients, this method may be a useful tool in CSF diagnostics and the longitudinal evaluation of patient with HAD...
  68. pmc Neuroimaging of infections
    Oliver Kastrup
    Department of Neurology, University Duisburg Essen, 45122 Essen, Germany
    NeuroRx 2:324-32. 2005
    ..In patients with herpes simplex and more exotic viruses like West Nile and Murray Valley virus DWI allows earlier lesion detection and therapeutic intervention with virustatic drugs...
  69. doi request reprint Substantia nigra hyperechogenicity and CSF dopamine depletion in HIV
    Mark Obermann
    Department of Neurology, University of Duisburg Essen, Hufelandstr 55, 45122, Essen, Germany
    J Neurol 256:948-53. 2009
    ..Our results indicate changes in the nigrostriatal system in HIV-infected patients that are detectable as hyperechogenic SN precede prominent extrapyramidal symptoms and cognitive dysfunction...
  70. ncbi request reprint Probabilistic 3D MRI atlas of the human cerebellar dentate/interposed nuclei
    A Dimitrova
    Department of Neurology, University of Duisburg Essen, Hufelandstrasse 44, 45122 Essen, Germany
    Neuroimage 30:12-25. 2006
    ..A probabilistic 3D MRI atlas of the cerebellar dentate/interposed nuclei is presented based on findings in all subjects...
  71. ncbi request reprint Impaired trigeminal nociceptive processing in patients with trigeminal neuralgia
    M Obermann
    Department of Neurology, University Duisburg Essen, Essen, Germany
    Neurology 69:835-41. 2007
    ..Between the attacks the patient is usually asymptomatic, but a constant dull background pain may persist in some cases. The mechanisms associated with the development of this chronic pain are not well understood...
  72. ncbi request reprint Clinical feature profile of spinocerebellar ataxia type 1-8 predicts genetically defined subtypes
    Matthias Maschke
    Department of Neurology, University of Duisburg Essen, Essen, Germany
    Mov Disord 20:1405-12. 2005
    ..Sensitivities and specificities found in the present study validate the use of algorithms to help to prioritize specific SCA gene testing, which will help to reduce costs for gene testing...
  73. ncbi request reprint Cerebellar responses evoked by nociceptive leg withdrawal reflex as revealed by event-related FMRI
    A Dimitrova
    Department of Neurology, University of Essen, 45122 Essen, Germany
    J Neurophysiol 90:1877-86. 2003
    ..Additional activation within vermal lobule VI and hemispheral lobules VI/Crus I may be related to other pain-related processes (e.g., facial grimacing, fear, and startlelike reactions)...
  74. ncbi request reprint Multiple intracerebral metastases of a 17-year-old girl with previously diagnosed neurofibromatosis type I
    M Maschke
    Department of Neurology, University of Essen, Germany
    Clin Neuropathol 18:42-4. 1999
    ..The patient was referred to the neurosurgical department, where two of the intracerebral tumors were excised. The histological examination revealed metastases of a neurosarcoma...
  75. doi request reprint Gray matter changes related to chronic posttraumatic headache
    Mark Obermann
    Department of Neurology, University of Duisburg Essen, 45122 Essen, Germany
    Neurology 73:978-83. 2009
    ..Although up to 15% of patients with whiplash injury develop chronic headache, the basis and mechanisms of this posttraumatic headache are not well understood...
  76. ncbi request reprint Cerebral aspergillosis: comparison of radiological and neuropathologic findings in patients with bone marrow transplantation
    U Dietrich
    Department of Neuroradiology, University Hospital, Essen, Germany
    Eur Radiol 11:1242-9. 2001
    ..Small lesions with high signal on T2WI and low signal on T1WI could not necessarily be related to Aspergillus infection...
  77. ncbi request reprint Is stereotactic biopsy a reliable method to differentiate tumor from radiation necrosis?
    C E Ehrenfeld
    Department of Neurology, University of Essen, Germany
    Clin Neuropathol 21:9-12. 2002
    ..This case demonstrates that radiation necrosis and tumor recurrence may develop concurrently and that it may be difficult to distinguish them by clinical or radiological methods...
  78. ncbi request reprint Increased basal-ganglia activation performing a non-dystonia-related task in focal dystonia
    M Obermann
    Department of Neurology, University of Duisburg Essen, Essen, Germany
    Eur J Neurol 15:831-8. 2008
    ....
  79. ncbi request reprint A placebo-controlled trial of gabapentin for painful HIV-associated sensory neuropathies
    K Hahn
    Department of Neurology, Charite Campus Mitte, Schumannstr 20 21, D 10117 Berlin, Germany
    J Neurol 251:1260-6. 2004
    ..The pathogenesis is unknown and the treatment very limited. Gabapentin (GBP) is effective in painful diabetic neuropathy and postherpetic neuralgia and its effectiveness on painful HIV-SN has been reported anecdotally...
  80. ncbi request reprint The perception of passive motion in Parkinson's disease
    Jurgen Konczak
    Human Sensorimotor Control Lab, University of Minnesota 400 Cooke Hall, 1900 University Ave S E, MN 55414, USA
    J Neurol 254:655-63. 2007
    ..The impaired processing of proprioceptive signals likely contributes to motor symptoms in PD...
  81. ncbi request reprint Copper deficiency myelopathy induced by repetitive parenteral zinc supplementation during chronic hemodialysis
    Ozgur Yaldizli
    J Neurol 253:1507-9. 2006