Research Topics
Species | Andreas H MarxSummaryAffiliation: University Medical Center Hamburg-Eppendorf Country: Germany Publications
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Detail Information
Publications
Homogeneous EGFR amplification defines a subset of aggressive Barrett's adenocarcinomas with poor prognosisAndreas H Marx
Institute of Pathology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
Histopathology 57:418-26. 2010..The aim of this study was performed to determine the potential impact of tumour heterogeneity on anti-EGFR therapy in Barrett's adenocarcinoma (BAC)...- AMACR expression in colorectal cancer is associated with left-sided tumor localizationAndreas Marx
Institute for Pathology, University Medical Center Hamburg Eppendorf, Martinistr 52, 20246 Hamburg, Germany
Virchows Arch 453:243-8. 2008..We hypothesize that the association of AMACR expression with tumor localization may be related to differences in the metabolism/exposure to fatty acids occurring along the colon... - Combined alpha-methylacyl coenzyme A racemase/p53 analysis to identify dysplasia in inflammatory bowel diseaseAndreas Marx
Institute of Pathology, University Medical Center Hamburg Eppendorf, 20246 Hamburg, Germany
Hum Pathol 40:166-73. 2009..It is concluded that combined alpha-methylacyl coenzyme A racemase/p53 analysis may represent a helpful tool to confirm dysplasia in inflammatory bowel disease... - HER-2 amplification is highly homogenous in gastric cancerAndreas H Marx
Institute of Pathology, University Medical Center Hamburg Eppendorf, Germany
Hum Pathol 40:769-77. 2009..The high level of HER-2 amplification in combination with the homogeneity of its expression in primary and metastatic tumors argues for a possible therapeutic utility of trastuzumab in HER-2-amplified gastric adenocarcinomas... - Heterogenous high-level HER-2 amplification in a small subset of colorectal cancersAndreas H Marx
Institute for Pathology, Hubertus Wald Tumorzentrum University Cancer Center Hamburg, University Medical Center Hamburg Eppendorf, Martinistr 52, 20246 Hamburg, Germany
Hum Pathol 41:1577-85. 2010..Heterogeneity of amplification may limit the utility of anti- HER-2 therapy in some of these tumors and therefore, adequate clinical trials are needed to further evaluate this approach... 
ALCAM (CD166) expression and serum levels in pancreatic cancerMichael Tachezy
Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg Eppendorf, Hamburg, Germany
PLoS ONE 7:e39018. 2012....- Overexpression of cell division cycle 7 homolog is associated with gene amplification frequency in breast cancerMatthias Choschzick
Institute of Pathology, University Medical Centre Hamburg Eppendorf, 20246 Hamburg, Germany
Hum Pathol 41:358-65. 2010..These data support the potential utility of newly developed small molecule cell division cycle 7 inhibitors as a therapeutic alternative in at least a subset of breast carcinomas... - ALCAM (CD166) expression as novel prognostic biomarker for pancreatic neuroendocrine tumor patientsMichael Tachezy
Department of General, Visceral, and Thoracic Surgery, University Medical Center Hamburg Eppendorf, Hamburg, Germany
J Surg Res 170:226-32. 2011..The aim of this study was to determine the expression of ALCAM in PNET to learn more about the prevalence and clinical significance of ALCAM expression in PNET... - Intratumoral heterogeneity of KRAS mutation is rare in non-small-cell lung cancerWinfried H Alsdorf
Institute of Pathology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
Exp Mol Pathol 94:155-9. 2013..This suggests heterogeneity of the primary tumor in respect to its KRAS status. We therefore aimed to examine the frequency and the extent of such intratumoral heterogeneity... - Heterogeneity of ERBB2 amplification in adenocarcinoma, squamous cell carcinoma and large cell undifferentiated carcinoma of the lungTobias J Grob
Department of Pathology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
Mod Pathol 25:1566-73. 2012..Heterogeneity of amplification may limit the utility of anti-HER2 therapy in some of these tumors. Further attempts to assess the utility of HER2-targeting therapy in homogeneously amplified lung cancers appear to be justified... - Omental infarction in the postpartum period: a case report and a review of the literatureMichael Tachezy
Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg Eppendorf, Martinistrase 52, 20246 Hamburg
J Med Case Reports 4:368. 2010..Omental infarction is a rare and often misdiagnosed clinical event with unspecific symptoms. It affects predominantly young and middle aged women... 
Frequent homogeneous HER-2 amplification in primary and metastatic adenocarcinoma of the esophagusUta Reichelt
Department of Pathology, University Medical Center Hamburg Eppendorf, University of Hamburg, Hamburg, Germany
Mod Pathol 20:120-9. 2007..The strong concordance of the HER-2 status in primary and metastatic cancers argues for a possible response of metastases from patients with HER-2-positive primary tumors to Herceptin...