Genomes and Genes
Affiliation: University of Wuerzburg
- THOC5/FMIP, an mRNA export TREX complex protein, is essential for hematopoietic primitive cell survival in vivoAnnalisa Mancini
Institut fuer Biochemie, OE4310, Medizinische Hochschule Hannover, Carl Neuberg Str, 1, D 30623 Hannover, Germany
BMC Biol 8:1. 2010..THO complex (THOC) components are not essential for bulk poly (A)+ RNA export in higher eukaryotes, but for the nuclear export of subset of mRNAs, however, their exact role is still unclear...
- The M-CSF receptor substrate and interacting protein FMIP is governed in its subcellular localization by protein kinase C-mediated phosphorylation, and thereby potentiates M-CSF-mediated differentiationAnnalisa Mancini
Institut fur Biochemie, OE 4310, Medizinische Hochschule Hannover, Carl Neuberg Str 1, D 30623 Hannover, Germany
Oncogene 23:6581-9. 2004..We conclude M-CSF-mediated activation of PKCalpha can potentiate FMIP action to initiate survival/differentiation signaling...
- The SH2-domian-containing inositol 5-phosphatase (SHIP)-2 binds to c-Met directly via tyrosine residue 1356 and involves hepatocyte growth factor (HGF)-induced lamellipodium formation, cell scattering and cell spreadingAlexandra Koch
Institut fur Biochemie, Medizinische Hochschule Hannover, OE 4310, Carl Neuberg Str 1, Hannover D 30623, Germany
Oncogene 24:3436-47. 2005....