Edward Malaga-Trillo

Summary

Affiliation: University of Konstanz
Country: Germany

Publications

  1. ncbi request reprint Evolution of duplicated reggie genes in zebrafish and goldfish
    Edward Malaga-Trillo
    Department of Biology, University of Konstanz, Germany
    J Mol Evol 54:235-45. 2002
  2. pmc Regulation of embryonic cell adhesion by the prion protein
    Edward Malaga-Trillo
    Department of Biology, University of Konstanz, Konstanz, Germany
    PLoS Biol 7:e55. 2009
  3. doi request reprint Fish models in prion biology: underwater issues
    Edward Malaga-Trillo
    Department of Biology, University of Konstanz, 78457 Konstanz, Germany
    Biochim Biophys Acta 1812:402-14. 2011
  4. pmc PrPs: Proteins with a purpose: Lessons from the zebrafish
    Edward Malaga-Trillo
    University of Konstanz, Department of Biology, Germany
    Prion 3:129-33. 2009
  5. ncbi request reprint Disparate evolution of prion protein domains and the distinct origin of Doppel- and prion-related loci revealed by fish-to-mammal comparisons
    Eric Rivera-Milla
    Department of Biology, University of Konstanz, Konstanz, Germany
    FASEB J 20:317-9. 2006
  6. ncbi request reprint Restricted expression of reggie genes and proteins during early zebrafish development
    Anne C von Philipsborn
    Department of Biology, University of Konstanz, 78467 Konstanz, Germany
    J Comp Neurol 482:257-72. 2005
  7. ncbi request reprint An evolutionary basis for scrapie disease: identification of a fish prion mRNA
    Eric Rivera-Milla
    Department of Biology, University of Konstanz, 78457, Konstanz, Germany
    Trends Genet 19:72-5. 2003
  8. pmc Reggie/flotillin proteins are organized into stable tetramers in membrane microdomains
    Gonzalo P Solis
    Department of Biology, University of Konstanz, 78467 Konstanz, Germany
    Biochem J 403:313-22. 2007
  9. ncbi request reprint Cellular roles of the prion protein in association with reggie/flotillin microdomains
    Gonzalo P Solis
    University of Konstanz, Department of Biology, 78457 Konstanz, Germany
    Front Biosci (Landmark Ed) 15:1075-85. 2010
  10. pmc Conserved roles of the prion protein domains on subcellular localization and cell-cell adhesion
    Gonzalo P Solis
    Department of Biology, University of Konstanz, Konstanz, Germany
    PLoS ONE 8:e70327. 2013

Collaborators

Detail Information

Publications12

  1. ncbi request reprint Evolution of duplicated reggie genes in zebrafish and goldfish
    Edward Malaga-Trillo
    Department of Biology, University of Konstanz, Germany
    J Mol Evol 54:235-45. 2002
    ..An evolutionary scenario for the evolution of reggie intron-exon structure, where loss of introns appears to be a distinctive trait in invertebrate reggie genes, is presented...
  2. pmc Regulation of embryonic cell adhesion by the prion protein
    Edward Malaga-Trillo
    Department of Biology, University of Konstanz, Konstanz, Germany
    PLoS Biol 7:e55. 2009
    ..Altogether, our data uncover evolutionarily conserved roles of PrP in cell communication, which ultimately impinge on the stability of adherens cell junctions during embryonic development...
  3. doi request reprint Fish models in prion biology: underwater issues
    Edward Malaga-Trillo
    Department of Biology, University of Konstanz, 78457 Konstanz, Germany
    Biochim Biophys Acta 1812:402-14. 2011
    ..This article is part of a Special Issue entitled Zebrafish Models of Neurological Diseases...
  4. pmc PrPs: Proteins with a purpose: Lessons from the zebrafish
    Edward Malaga-Trillo
    University of Konstanz, Department of Biology, Germany
    Prion 3:129-33. 2009
    ..Importantly, these molecular functions of PrP are conserved from fish to mammals. Here we discuss the use of the zebrafish in prion biology and how it may advance our understanding of the roles of PrP in health and disease...
  5. ncbi request reprint Disparate evolution of prion protein domains and the distinct origin of Doppel- and prion-related loci revealed by fish-to-mammal comparisons
    Eric Rivera-Milla
    Department of Biology, University of Konstanz, Konstanz, Germany
    FASEB J 20:317-9. 2006
    ....
  6. ncbi request reprint Restricted expression of reggie genes and proteins during early zebrafish development
    Anne C von Philipsborn
    Department of Biology, University of Konstanz, 78467 Konstanz, Germany
    J Comp Neurol 482:257-72. 2005
    ..Upon segmentation, a second phase of expression shows distinctly localized expression patterns, indicating tissue-specific roles and an involvement of re-1a/re-2a in neural development...
  7. ncbi request reprint An evolutionary basis for scrapie disease: identification of a fish prion mRNA
    Eric Rivera-Milla
    Department of Biology, University of Konstanz, 78457, Konstanz, Germany
    Trends Genet 19:72-5. 2003
    ..We propose that a directional trend in the evolution of prion sequence motifs associated with pathogenesis and infectivity could account for the origin of scrapie in mammals...
  8. pmc Reggie/flotillin proteins are organized into stable tetramers in membrane microdomains
    Gonzalo P Solis
    Department of Biology, University of Konstanz, 78467 Konstanz, Germany
    Biochem J 403:313-22. 2007
    ..Our data indicate that the basic structural units of reggie microdomains are reggie homo- and hetero-tetramers, which are dependent on the presence of reggie-1...
  9. ncbi request reprint Cellular roles of the prion protein in association with reggie/flotillin microdomains
    Gonzalo P Solis
    University of Konstanz, Department of Biology, 78457 Konstanz, Germany
    Front Biosci (Landmark Ed) 15:1075-85. 2010
    ....
  10. pmc Conserved roles of the prion protein domains on subcellular localization and cell-cell adhesion
    Gonzalo P Solis
    Department of Biology, University of Konstanz, Konstanz, Germany
    PLoS ONE 8:e70327. 2013
    ..Furthermore, they show that despite their large evolutionary history, the roles of PrP domains and posttranslational modifications are conserved between mouse and zebrafish. ..
  11. doi request reprint Origin of Nogo-A by domain shuffling in an early jawed vertebrate
    Aleksandra Shypitsyna
    Department of Biology, University of Konstanz, Konstanz, Germany
    Mol Biol Evol 28:1363-70. 2011
    ..Notably, the shared presence of transposable elements in ncan and rtn4 genes suggests that Nogo-A originated via insertion of an ncan-like sequence into the rtn4 gene of an early jawed vertebrate with myelinated axons...
  12. doi request reprint Reggies/flotillins regulate retinal axon regeneration in the zebrafish optic nerve and differentiation of hippocampal and N2a neurons
    Christina Munderloh
    Department of Biology, University of Konstanz, D 78457 Konstanz, Germany
    J Neurosci 29:6607-15. 2009
    ....