Research Topics
Genomes and Genes | Edward Malaga-TrilloSummaryAffiliation: University of Konstanz Country: Germany Publications
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Detail Information
Publications
Evolution of duplicated reggie genes in zebrafish and goldfishEdward Malaga-Trillo
Department of Biology, University of Konstanz, Germany
J Mol Evol 54:235-45. 2002..An evolutionary scenario for the evolution of reggie intron-exon structure, where loss of introns appears to be a distinctive trait in invertebrate reggie genes, is presented...
Regulation of embryonic cell adhesion by the prion proteinEdward Malaga-Trillo
Department of Biology, University of Konstanz, Konstanz, Germany
PLoS Biol 7:e55. 2009..Altogether, our data uncover evolutionarily conserved roles of PrP in cell communication, which ultimately impinge on the stability of adherens cell junctions during embryonic development...
Fish models in prion biology: underwater issuesEdward Malaga-Trillo
Department of Biology, University of Konstanz, 78457 Konstanz, Germany
Biochim Biophys Acta 1812:402-14. 2011..This article is part of a Special Issue entitled Zebrafish Models of Neurological Diseases...
PrPs: Proteins with a purpose: Lessons from the zebrafishEdward Malaga-Trillo
University of Konstanz, Department of Biology, Germany
Prion 3:129-33. 2009..Importantly, these molecular functions of PrP are conserved from fish to mammals. Here we discuss the use of the zebrafish in prion biology and how it may advance our understanding of the roles of PrP in health and disease...
Restricted expression of reggie genes and proteins during early zebrafish developmentAnne C von Philipsborn
Department of Biology, University of Konstanz, 78467 Konstanz, Germany
J Comp Neurol 482:257-72. 2005..Upon segmentation, a second phase of expression shows distinctly localized expression patterns, indicating tissue-specific roles and an involvement of re-1a/re-2a in neural development...
Disparate evolution of prion protein domains and the distinct origin of Doppel- and prion-related loci revealed by fish-to-mammal comparisonsEric Rivera-Milla
Department of Biology, University of Konstanz, Konstanz, Germany
FASEB J 20:317-9. 2006....
Reggie/flotillin proteins are organized into stable tetramers in membrane microdomainsGonzalo P Solis
Department of Biology, University of Konstanz, 78467 Konstanz, Germany
Biochem J 403:313-22. 2007..Our data indicate that the basic structural units of reggie microdomains are reggie homo- and hetero-tetramers, which are dependent on the presence of reggie-1...
Cellular roles of the prion protein in association with reggie/flotillin microdomainsGonzalo P Solis
University of Konstanz, Department of Biology, 78457 Konstanz, Germany
Front Biosci 15:1075-85. 2010....
Origin of Nogo-A by domain shuffling in an early jawed vertebrateAleksandra Shypitsyna
Department of Biology, University of Konstanz, Konstanz, Germany
Mol Biol Evol 28:1363-70. 2011..Notably, the shared presence of transposable elements in ncan and rtn4 genes suggests that Nogo-A originated via insertion of an ncan-like sequence into the rtn4 gene of an early jawed vertebrate with myelinated axons...
Reggies/flotillins regulate retinal axon regeneration in the zebrafish optic nerve and differentiation of hippocampal and N2a neuronsChristina Munderloh
Department of Biology, University of Konstanz, D 78457 Konstanz, Germany
J Neurosci 29:6607-15. 2009....
