Research Topics
| Andrea G LudolphSummaryAffiliation: University of Ulm Country: Germany Publications
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Detail Information
Publications
Tourette syndrome and other tic disorders in childhood, adolescence and adulthoodAndrea G Ludolph
Department of Child and Adolescent Psychiatry and Psychotherapy, Ulm University Hospital, Ulm, Germany
Dtsch Arztebl Int 109:821-288. 2012..It arises in about 1% of all children, with highly varying severity. Transient and usually mild tics are seen in as many as 15% of all children in elementary school. The diagnosis is often delayed by several years...- Atomoxetine acts as an NMDA receptor blocker in clinically relevant concentrationsAndrea G Ludolph
Department of Child and Adolescent Psychiatry, University of Ulm, Germany
Br J Pharmacol 160:283-91. 2010..Atomoxetine, a selective noradrenaline reuptake inhibitor, is the first non-stimulant approved for the treatment of this disorder. Here we have evaluated the effects of atomoxetine on glutamate receptors in vitro... 
[Attention Deficit Hyperactivity Disorder (ADHD) and road traffic - special considerations for the treatment of adolescents with ADHD]Andrea G Ludolph
Klinik fur Kinder und Jugendpsychiatrie und psychotherapie, Universitatsklinikum Ulm, Ulm
Z Kinder Jugendpsychiatr Psychother 37:405-11. 2009..Given the high number of traffic deaths in these young age groups consulting regarding this matter should be of high priority...
Methylphenidate exerts no neurotoxic, but neuroprotective effects in vitroA G Ludolph
Department of Child and Adolescent Psychiatry, University of Ulm, Ulm, Germany
J Neural Transm 113:1927-34. 2006..The neurotoxic effects of MPP(+) could be significantly reduced by co-application of MPH, an effect that is most likely explained by MPH blocking the DAT...- Dose-dependent modulation of apoptotic processes by fluoxetine in maturing neuronal cells: an in vitro studyUlrike Schaz
Institute of Anatomy and Cell Biology, University of Ulm, Ulm, Germany
World J Biol Psychiatry 12:89-98. 2011..Recent studies indicate that the selective serotonin reuptake inhibitor (SSRI) fluoxetine is not solely effective by the instant inhibition of the serotonin transporter (SERT) but also by its influence on mitotic and/or apoptotic processes... - Intensified testing for attention-deficit hyperactivity disorder (ADHD) in girls should reduce depression and smoking in adult females and the prevalence of ADHD in the longtermElmar H Pinkhardt
Department of Neurology, University of Ulm, Germany
Med Hypotheses 72:409-12. 2009.... - Dopaminergic dysfunction in attention deficit hyperactivity disorder (ADHD), differences between pharmacologically treated and never treated young adults: a 3,4-dihdroxy-6-[18F]fluorophenyl-l-alanine PET studyAndrea G Ludolph
Department of Child and Adolescent Psychiatry, University of Ulm, Germany
Neuroimage 41:718-27. 2008..MP seems to down-regulate dopamine turnover. This effect might be one component in the mechanism of action of this drug in ADHD treatment... - Neurodevelopmental and neurodegenerative diseases - is there a pathophysiological link? Attention-deficit/hyperactivity disorder and amyotrophic lateral sclerosis as examplesD Lule
Department of Neurology Neurophysiology, Oberer Eselsberg 47, University of Ulm, 89081 Ulm, Germany
Med Hypotheses 70:1133-8. 2008..Our hypothesis of a link between ADHD and ALS could also be considered as an example how research on neurodevelopmental diseases might influence the understanding and possibly the prevention and treatment of neurodegenerative diseases... - Safeguarding children's rights in psychopharmacological research: ethical and legal issuesMichael Kölch
Department of Child and Adolescent Psychiatry and Psychotherapy, University Hospital of Ulm, Steinhövelstr 5, 89075 Ulm, Germany
Curr Pharm Des 16:2398-406. 2010..Considering the important legislative changes in pediatric research over the past decade in both the US and Western Europe, there is a need to review recent developments in this area... - Are amygdalar volume alterations in children with Tourette syndrome due to ADHD comorbidity?Andrea G Ludolph
Department of Child and Adolescent Psychiatry, University of Ulm, Oberer Eselsberg 45, Ulm, Germany
Dev Med Child Neurol 50:524-9. 2008..Future studies should investigate if the involvement of the amygdala is due to TS or rather caused by the genetically-linked most frequent comorbidity ADHD... - European clinical guidelines for Tourette syndrome and other tic disorders. Part II: pharmacological treatmentVeit Roessner
Department of Child and Adolescent Psychiatry, University of Dresden Medical School, Fetscherstrasse 74, 01307 Dresden, Germany
Eur Child Adolesc Psychiatry 20:173-96. 2011..This summary is, however, rather a status quo of a clinically helpful but merely low evidence guideline, mainly driven by expert experience and opinion, since rigorous experimental studies are scarce... - Prone to excitement: adolescent females with Non-suicidal self-injury (NSSI) show altered cortical pattern to emotional and NSS-related materialPaul L Plener
Department of Child and Adolescent Psychiatry and Psychotherapy, University of Ulm, Ulm, Germany
Psychiatry Res 203:146-52. 2012..Behavioural data highlight proneness to excitement regarding NSSI topics. This fMRI study provides evidence for emotion-regulation deficits in the developing brain of adolescents with NSSI... - Grey-matter abnormalities in boys with Tourette syndrome: magnetic resonance imaging study using optimised voxel-based morphometryAndrea G Ludolph
Department of Child and Adolescent Psychiatry, University of Ulm, Oberer Eselsberg 45, 889081 Ulm, Germany
Br J Psychiatry 188:484-5. 2006..This unbiased analysis confirmed an association between striatal abnormalities and Tourette syndrome, and the hippocampal volume alterations indicate an involvement of temporolimbic pathways of the CSTC in the syndrome...