A Luchner

Summary

Affiliation: University of Regensburg
Country: Germany

Publications

  1. ncbi request reprint Comparison of the cardiac markers B-type natriuretic peptide and N-terminal pro B-type natriuretic peptide
    Stefan Buchner
    , Kardiologie, , Franz Josef Strauss Allee 11, 93042 Regensburg, Germany
    Biomark Med 3:465-81. 2009
  2. doi request reprint N-terminal pro brain natriuretic peptide in the management of patients in the medical emergency department (PROMPT): correlation with disease severity, utilization of hospital resources, and prognosis in a large, prospective, randomized multicentre trial
    Andreas Luchner
    Kliniken und Polikliniken für Innere Medizin I und II, Universitatsklinikum, F J Strauss Allee 11, Regensburg, Germany
    Eur J Heart Fail 14:259-67. 2012
  3. pmc Time course of eosinophilic myocarditis visualized by CMR
    Kurt Debl
    Klinik und Poliklinik fur Innere Medizin II, Klinikum der Universitat, Regensburg, Germany
    J Cardiovasc Magn Reson 10:21. 2008
  4. pmc Electrocardiographic diagnosis of left ventricular hypertrophy in aortic valve disease: evaluation of ECG criteria by cardiovascular magnetic resonance
    Stefan Buchner
    Klinik und Poliklinik fur Innere Medizin II, Universitatsklinikum Regensburg, Germany
    J Cardiovasc Magn Reson 11:18. 2009
  5. pmc Eplerenone prevents salt-induced vascular stiffness in Zucker diabetic fatty rats: a preliminary report
    Markus Resch
    Department of Internal Medicine II, Regensburg University Medical Center, Germany
    Cardiovasc Diabetol 10:94. 2011
  6. doi request reprint Improvement of the cardiac marker N-terminal-pro brain natriuretic peptide through adjustment for renal function: a stratified multicenter trial
    Andreas Luchner
    Klinik und Poliklinik fur Innere Medizin II, Klinikum der Universitat Regensburg, Regensburg, Germany
    Clin Chem Lab Med 48:121-8. 2010
  7. ncbi request reprint Effect of compensated renal dysfunction on approved heart failure markers: direct comparison of brain natriuretic peptide (BNP) and N-terminal pro-BNP
    Andreas Luchner
    Klinik und Poliklinik fur Innere Medizin II, University of Regensburg, Germany
    Hypertension 46:118-23. 2005
  8. ncbi request reprint Interactions between the sympathetic nervous system and the cardiac natriuretic peptide system
    A Luchner
    Klinik und Poliklinik fur Innere Medizin II, Klinikum der Universitat Regensburg, Franz Josef Strauss Allee 11, Regensburg 93042, Germany
    Cardiovasc Res 63:443-9. 2004
  9. ncbi request reprint N-terminal pro-brain natriuretic peptide after myocardial infarction: a marker of cardio-renal function
    Andreas Luchner
    Klinik und Poliklinik fur Innere Medizin II, Klinikum der Universitat, Regensburg, Germany
    Hypertension 39:99-104. 2002
  10. ncbi request reprint Relationship between left ventricular wall stress and ANP gene expression during the evolution of rapid ventricular pacing-induced heart failure in the dog
    A Luchner
    Klinik und Poliklinik fur Innere Medizin II, Universitat Regensburg, F J Strauss Allee 11, 93042 Regensburg, Germany
    Eur J Heart Fail 2:379-86. 2000

Collaborators

Detail Information

Publications33

  1. ncbi request reprint Comparison of the cardiac markers B-type natriuretic peptide and N-terminal pro B-type natriuretic peptide
    Stefan Buchner
    , Kardiologie, , Franz Josef Strauss Allee 11, 93042 Regensburg, Germany
    Biomark Med 3:465-81. 2009
    ....
  2. doi request reprint N-terminal pro brain natriuretic peptide in the management of patients in the medical emergency department (PROMPT): correlation with disease severity, utilization of hospital resources, and prognosis in a large, prospective, randomized multicentre trial
    Andreas Luchner
    Kliniken und Polikliniken für Innere Medizin I und II, Universitatsklinikum, F J Strauss Allee 11, Regensburg, Germany
    Eur J Heart Fail 14:259-67. 2012
    ..N-terminal pro brain natriuretic peptide (NT-proBNP) is a potent marker of heart failure and other cardiac diseases. The value of NT-proBNP testing in the medical emergency department (ED) was assessed in patients >65 years old...
  3. pmc Time course of eosinophilic myocarditis visualized by CMR
    Kurt Debl
    Klinik und Poliklinik fur Innere Medizin II, Klinikum der Universitat, Regensburg, Germany
    J Cardiovasc Magn Reson 10:21. 2008
    ..This case therefore highlights the clinical importance of CMR to visualize the extent of endomyocardial involvement in the diagnosis and treatment of eosinophilic myocarditis...
  4. pmc Electrocardiographic diagnosis of left ventricular hypertrophy in aortic valve disease: evaluation of ECG criteria by cardiovascular magnetic resonance
    Stefan Buchner
    Klinik und Poliklinik fur Innere Medizin II, Universitatsklinikum Regensburg, Germany
    J Cardiovasc Magn Reson 11:18. 2009
    ..Additionally, the effects of concentric and eccentric LVH on depolarization and repolarization were assessed...
  5. pmc Eplerenone prevents salt-induced vascular stiffness in Zucker diabetic fatty rats: a preliminary report
    Markus Resch
    Department of Internal Medicine II, Regensburg University Medical Center, Germany
    Cardiovasc Diabetol 10:94. 2011
    ..The aim of this study was to examine the effect of the aldosterone antagonist eplerenone on structural and mechanical properties of resistance arteries of ZDF-rats on normal and high-salt diet...
  6. doi request reprint Improvement of the cardiac marker N-terminal-pro brain natriuretic peptide through adjustment for renal function: a stratified multicenter trial
    Andreas Luchner
    Klinik und Poliklinik fur Innere Medizin II, Klinikum der Universitat Regensburg, Regensburg, Germany
    Clin Chem Lab Med 48:121-8. 2010
    ..It was our objective to assess the relationship between NT-proBNP concentrations in plasma and worsening renal function, and to attempt adjustment of NT-proBNP for renal dysfunction in a prospective, stratified multi-center study...
  7. ncbi request reprint Effect of compensated renal dysfunction on approved heart failure markers: direct comparison of brain natriuretic peptide (BNP) and N-terminal pro-BNP
    Andreas Luchner
    Klinik und Poliklinik fur Innere Medizin II, University of Regensburg, Germany
    Hypertension 46:118-23. 2005
    ..Renal dysfunction is a potential cause of elevated marker concentrations in the absence of LVD, and cut-off concentrations should be stratified according to renal function...
  8. ncbi request reprint Interactions between the sympathetic nervous system and the cardiac natriuretic peptide system
    A Luchner
    Klinik und Poliklinik fur Innere Medizin II, Klinikum der Universitat Regensburg, Franz Josef Strauss Allee 11, Regensburg 93042, Germany
    Cardiovasc Res 63:443-9. 2004
    ..In the current manuscript, results from in vivo and in vitro studies will be reviewed with a focus on sympathetic outflow on the control of natriuretic peptide release...
  9. ncbi request reprint N-terminal pro-brain natriuretic peptide after myocardial infarction: a marker of cardio-renal function
    Andreas Luchner
    Klinik und Poliklinik fur Innere Medizin II, Klinikum der Universitat, Regensburg, Germany
    Hypertension 39:99-104. 2002
    ..Cutoff concentrations have to be chosen according to renal function to optimize the predictive value of NT-proBNP...
  10. ncbi request reprint Relationship between left ventricular wall stress and ANP gene expression during the evolution of rapid ventricular pacing-induced heart failure in the dog
    A Luchner
    Klinik und Poliklinik fur Innere Medizin II, Universitat Regensburg, F J Strauss Allee 11, 93042 Regensburg, Germany
    Eur J Heart Fail 2:379-86. 2000
    ..The current studies provide new insight into the temporal pattern of ANP-activation and the disparity between left ventricular systolic wall stress and ANP-activation in a large animal model of progressive CHF...
  11. ncbi request reprint Differential expression of cardiac ANP and BNP in a rabbit model of progressive left ventricular dysfunction
    A Luchner
    Klinik und Poliklinik fur Innere Medizin II, Klinikum der Universitat Regensburg, F J Strauss Allee 11, 93042, Regensburg, Germany
    Cardiovasc Res 51:601-7. 2001
    ....
  12. ncbi request reprint Contribution of the endothelin system to the renal hypoperfusion associated with experimental congestive heart failure
    E B Friedrich
    Klinik und Poliklinik fur Innere Medizin II, Universitat Regensburg, Germany
    J Cardiovasc Pharmacol 34:612-7. 1999
    ..They indicate a principal functional role for the ETA receptor in renal vasoconstriction and suggest blockade of the renal ETA receptor as an important strategy to attenuate renal hypoperfusion in CHF...
  13. ncbi request reprint Alterations in myocardial creatinine kinase (CK) and lactate dehydrogenase (LDH) isoenzyme-distribution in a model of left ventricular dysfunction
    F Muders
    , , 93042, Regensburg, Germany
    Eur J Heart Fail 3:1-5. 2001
    ..The current study demonstrates changes in cardiac energy metabolism including an impaired LDH activity with a shift towards anaerobic isoenzymes as well as a more efficient CK system in a model of catecholamine-induced LV dysfunction...
  14. doi request reprint Quantification of left-to-right shunting in adult congenital heart disease: phase-contrast cine MRI compared with invasive oximetry
    K Debl
    Klinik und Poliklinik fur Innere Medizin II, Universitatsklinikum Regensburg, Germany
    Br J Radiol 82:386-91. 2009
    ..75:1 (area under curve (AUC) = 0.99). Quantification of left-to-right shunting can be performed reliably and accurately by PC-MRI and the data obtained by this method correlate closely to those from invasive oximetry...
  15. ncbi request reprint Familial predisposition of left ventricular hypertrophy
    H Schunkert
    Klinik und Poliklinik fur Innere Medizin II, University of Regensburg, Germany
    J Am Coll Cardiol 33:1685-91. 1999
    ..The study evaluated the contribution of familial predisposition to the risk of left ventricular hypertrophy (LVH)...
  16. ncbi request reprint Differential effects of antihypertensive drugs on neurohormonal activation: insights from a population-based sample
    H Schunkert
    Klinik und Poliklinik fur Innere Medizin II, University of Regensburg, Germany
    J Intern Med 244:109-19. 1998
    ..In the present study, we examined the relative contribution of antihypertensive therapy to the variability of neurohormonal levels in a well defined population based sample...
  17. doi request reprint Increased aldosterone levels in a model of type 2 diabetes mellitus
    S Fredersdorf
    Klinik und Poliklinik fur Innere Medizin II, University of Regensburg, Regensburg, Germany
    Exp Clin Endocrinol Diabetes 117:15-20. 2009
    ....
  18. ncbi request reprint Lack of association between a polymorphism of the aldosterone synthase gene and left ventricular structure
    H Schunkert
    Klinik und Poliklinik fur Innere Medizin II, University of Regensburg, Regensburg, Germany
    Circulation 99:2255-60. 1999
    ..The aim of the present study was to reinvestigate the implications of aldosterone synthase -344C/T allele status for serum aldosterone levels, blood pressure, and LV structure and function in large population-based samples...
  19. ncbi request reprint Assessment of the anatomic regurgitant orifice in aortic regurgitation: a clinical magnetic resonance imaging study
    K Debl
    Klinik und Poliklinik fur Innere Medizin II, Klinikum der Universitat, Regensburg, Germany
    Heart 94:e8. 2008
    ....
  20. ncbi request reprint BNP as a marker of diastolic dysfunction in the general population: Importance of left ventricular hypertrophy
    T V Lukowicz
    Klinik und Poliklinik fur Innere Medizin II, Klinikum der Universitat Regensburg, 93042 Regensburg, Germany
    Eur J Heart Fail 7:525-31. 2005
    ..Population-wide screening for diastolic dysfunction with BNP cannot be recommended although a normal BNP test usually excludes diastolic dysfunction and LV hypertrophy...
  21. ncbi request reprint Modulation of renal blood flow by endogenous endothelin-1 in conscious rabbits with left ventricular dysfunction
    F Muders
    , , Regensburg, Germany
    Am J Hypertens 12:835-8. 1999
    ..05) in heart failure. The current study provides new insight into the pathophysiology of renal vasoconstriction associated with heart failure and the specific role of the renal ET(A) receptor in this pathophysiologic adaptation...
  22. doi request reprint Safety of the novel atrial-selective K+-channel blocker AVE0118 in experimental heart failure
    H J Schneider
    Klinik und Poliklinik fur Innere Medizin II, University of Regensburg, Franz Josef Strauss Allee 11, 93053, Regensburg, Germany
    Naunyn Schmiedebergs Arch Pharmacol 379:225-32. 2009
    ..In conclusion, atrial-selective K(+)-channel blockade by AVE0118 appears safe in experimental CHF...
  23. ncbi request reprint MRI planimetry for diagnosis and follow-up of valve area in mitral stenosis treated with valvuloplasty
    B Djavidani
    Institut für Röntgendiagnostik, Universitatsklinikum Regensburg, Regensburg
    Rofo 178:781-6. 2006
    ....
  24. ncbi request reprint [64-year-old patient with dyspnea at risk and ankle edema in recurrent tachycardia. Heart failure]
    M Stubanus
    Klinik und Poliklinik fur Innere Medizin II, Klinikum der Universitat Regensburg, Franz Josef Strauss Allee 11, 93053 Regensburg
    Internist (Berl) 43:1597-601. 2002
  25. doi request reprint Effects of selective and unselective endothelin-receptor antagonists on prostacyclin synthase gene expression in experimental pulmonary hypertension
    S Schroll
    Department of Internal Medicine II, Pneumology, University of Regensburg, Germany
    Scand J Clin Lab Invest 68:270-6. 2008
    ..Our hypothesis was that treatment with Ambrisentan leads to an increase in prostacyclin synthase I (PGIS) expression compared to Bosentan...
  26. pmc Delayed hyperenhancement in magnetic resonance imaging of left ventricular hypertrophy caused by aortic stenosis and hypertrophic cardiomyopathy: visualisation of focal fibrosis
    K Debl
    Klinik und Poliklinik fur Innere Medizin II, Klinikum der Universitat, Regensburg, Germany
    Heart 92:1447-51. 2006
    ....
  27. ncbi request reprint [48-year old woman with diffuse pulmonary calcifications after allogeneic kidney transplantation. A rare manifestation of tertiary hyperparathyroidism]
    T Leingärtner
    Klinik und Poliklinik fur Innere Medizin II, Klinikum der Universitat Regensburg
    Med Klin (Munich) 96:408-13. 2001
    ..The patient had had an end-stage renal disease of unknown cause and was on hemodialysis since 1993. 1997 she received a cadaveric renal transplant...
  28. doi request reprint Extracorporeal pumpless interventional lung assist in clinical practice: determinants of efficacy
    T Muller
    Department of Internal Medicine II, University Hospital of Regensburg, Franz Josef Strauss Allee 11, 93053 Regensburg, Germany
    Eur Respir J 33:551-8. 2009
    ..Despite limited contribution to oxygen transfer it may allow a more protective ventilation in severe respiratory failure...
  29. ncbi request reprint Mechanisms of regional wall motion abnormalities in contrast-enhanced dobutamine stress echocardiography
    N Heinicke
    Klinik und Poliklinik fur Innere Medizin II, University of Regensburg, 93042, Regensburg, Germany
    Clin Res Cardiol 95:650-6. 2006
    ..In the diagnosis of coronary artery disease (CAD) with Dobutamine Stress Echocardiography (DSE), regional wall motion abnormalities (RWMA) are assumed to indicate a perfusion deficit...
  30. ncbi request reprint Clinical applications of B-type natriuretic peptide (BNP) testing
    M R Cowie
    National Heart and Lung Institute, Imperial College, London, UK
    Eur Heart J 24:1710-8. 2003
    ..However, as BNP levels rise with age and are affected by gender, comorbidity and drug therapy, the plasma BNP measurement should not be used in isolation from the clinical context...
  31. ncbi request reprint [Epidemiology of left ventricular systolic dysfunction in the general population of Germany: results of an echocardiographic study of a large population-based sample]
    M Fischer
    Klinik und Poliklinik für Innere Medizin, Universitat Regensburg, Germany
    Z Kardiol 92:294-302. 2003
    ..However, severe LVSD is rare in subjects without any concomitant cardiovascular disease. Thus, echocardiographic screening cannot be recommended in the unselected, middle-aged population to identify such patients...
  32. ncbi request reprint NT-proBNP and the diagnosis of heart failure: a pooled analysis of three European epidemiological studies
    T A McDonagh
    Department of Cardiology, Royal and Western Infirmaries, University of Glasgow, 10 Alexandra Parade, Glasgow, Scotland G31 2ER, UK
    Eur J Heart Fail 6:269-73. 2004
    ..An elevated NT-proBNP merely indicates the presence of 'cardio-renal distress' and should prompt referral for further investigation...
  33. doi request reprint Unicuspid aortic valve disease: a magnetic resonance imaging study
    K Debl
    Klinik und Poliklinik fur Innere Medizin II, Universitatsklinikum Regensburg
    Rofo 180:983-7. 2008
    ..The aim of our study was to describe valve morphology and the dimensions of the proximal aorta in a cohort of 12 patients with UAV in comparison to tricuspid aortic valve disease (TAV) using magnetic resonance imaging (MRI)...