Research Topics
| Jürgen LorenzSummaryAffiliation: University of Hamburg Country: Germany Publications
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Detail Information
Publications
Cognitive performance, mood and experimental pain before and during morphine-induced analgesia in patients with chronic non-malignant painJ Lorenz
Institute of Physiology, University Hospital Eppendorf, Hamburg, Germany
Pain 73:369-75. 1997....- Hyperalgesia or hypervigilance? An evoked potential approach to the study of fibromyalgia syndromeJ Lorenz
Institute of Physiology, University Hospital Eppendorf, Hamburg, Germany
Z Rheumatol 57:19-22. 1998..Yet, the importance of unpleasant intensities of auditory stimulation, not applied in this study, to reveal abnormal non-nociceptive perceptual amplification in FS is discussed... - Keeping pain out of mind: the role of the dorsolateral prefrontal cortex in pain modulationJ Lorenz
Department of Neurology, University of Michigan, Neurology Research Laboratories, Veterans Affairs Medical Center, Ann Arbor, MI, USA
Brain 126:1079-91. 2003..We propose that the DLPFC exerts active control on pain perception by modulating corticosubcortical and corticocortical pathways... - Imaging of acute versus pathological pain in humansJ Lorenz
Institute of Neurophysiology and Pathophysiology, University Clinic Hamburg Eppendorf, Martinistrasse 52, D 20246 Hamburg, Germany
Eur J Pain 9:163-5. 2005.... - Contribution of attentional and cognitive factors to laser evoked brain potentialsJürgen Lorenz
Institute of Neurophysiology and Pathophysiology, University Clinic Hamburg Eppendorf, Hamburg, Germany
Neurophysiol Clin 33:293-301. 2003..This composite entity needs to be considered when LEP are experimentally or clinically used in the assessment of sensory and cognitive phenomena and abnormalities of pain sensation... - A unique representation of heat allodynia in the human brainJürgen Lorenz
Department Neurology, University of Michigan, Ann Arbor, MI 48109, USA
Neuron 35:383-93. 2002..In making this differentiation, the brain recognizes unique physiological features of different painful conditions, thus permitting adaptive responses to different pain states... - Psychophysical and cerebral responses to heat stimulation in patients with central pain, painless central sensory loss, and in healthy personsKenneth L Casey
Department of Neurology, University of Michigan, Ann Arbor, Michigan 48104, USA
Pain 153:331-41. 2012..The increased nociceptive excitability within the intralaminar thalamus and sensory-motor cortex of our sample of CP patients suggests an underlying pathophysiology for the pain in some central pain syndromes... - Cortical correlates of false expectations during pain intensity judgments--a possible manifestation of placebo/nocebo cognitionsJürgen Lorenz
Institute of Neurophysiology and Pathophysiology, University Clinic Hamburg Eppendorf, Hamburg, Germany
Brain Behav Immun 19:283-95. 2005..This result suggests a priming of early cortical nociceptive sensitivity by cues signaling pain severity. A possible contribution of the SII cortex to the manifestation of nocebo/placebo cognitions is discussed... - Activation of the opioidergic descending pain control system underlies placebo analgesiaFalk Eippert
Department of Systems Neuroscience, University Medical Center Hamburg Eppendorf, Hamburg, Germany
Neuron 63:533-43. 2009..These findings show that opioidergic signaling in pain-modulating areas and the projections to downstream effectors of the descending pain control system are crucially important for placebo analgesia... - Role of synchronized oscillatory brain activity for human pain perceptionMichael Hauck
Department of Neurophysiology and Pathophysiology, University Medical Center Hamburg Eppendorf, Germany
Rev Neurosci 19:441-50. 2008..The importance of synchronization processes for normal and pathological pain processing, such as chronic pain states, is discussed... - Attention to painful stimulation enhances gamma-band activity and synchronization in human sensorimotor cortexMichael Hauck
Department of Neurophysiology and Pathophysiology, University Medical Center Hamburg Eppendorf, 20246 Hamburg, Germany
J Neurosci 27:9270-7. 2007.... - Duration of the cue-to-pain delay increases pain intensity: a combined EEG and MEG studyMichael Hauck
Department of Neurophysiology and Pathophysiology, University Medical Center Eppendorf, Martinistr 52, 20246 Hamburg, Germany
Exp Brain Res 180:205-15. 2007..Although this reaction is adaptive if the individual is able to avoid the stimulus, it is maladaptive if such opportunity is not present... - Evidence for early activation of primary motor cortex and SMA after electrical lower limb stimulation using EEG source reconstructionMichael Hauck
Department of Neurophysiology and Pathophysiology, University Medical Center Hamburg Eppendorf, Martinistr 52, 20246 Hamburg, Germany
Brain Res 1125:17-25. 2006..We conclude that a focused view on SEP of the lower limb could be a useful tool to investigate pathological states in motor control or peripheral deafferentiation... - Mechanisms of placebo analgesia: rACC recruitment of a subcortical antinociceptive networkU Bingel
NeuroImage Nord, Institute for Systems Neuroscience, University Medical Center Hamburg Eppendorf, Germany
Pain 120:8-15. 2006..This finding supports the view that placebo analgesia depends on the enhanced functional connectivity of the rACC with subcortical brain structures that are crucial for conditioned learning and descending inhibition of nociception... - Somatotopic organization of human somatosensory cortices for pain: a single trial fMRI studyU Bingel
Cognitive Neuroscience Laboratory, Department of Neurology, Hamburg University Medical School, Germany
Neuroimage 23:224-32. 2004.... - Temporal and spatial dynamics of human forebrain activity during heat pain: analysis by positron emission tomographyK L Casey
Department of Neurology, Department of Internal Medicine, University of Michigan, Ann Arbor 48105, USA
J Neurophysiol 85:951-9. 2001.... - Habituation to pain: further support for a central componentC Rennefeld
Department of Neurology, University of Hamburg UKE, Germany
Pain 148:503-8. 2010..Taken together, these results strongly support the role of central components in the mechanism of pain habituation that do not directly involve the endogenous opioid system... - Insights into the pathophysiology of neuropathic pain through functional brain imagingKenneth L Casey
Department of Neurology and Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI 48105, USA
Exp Neurol 184:S80-8. 2003..Functional imaging, including PET, fMRI, and neurophysiological techniques, should help identify brain mechanisms that are critical targets for more effective and more specific treatments for chronic, neuropathic pain... - Somatotopy of placebo analgesia is independent of spatial attentionClaudia Domnick
Department of Neurophysiology and Pathophysiology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
J Pain Res 4:79-83. 2011..This result rather suggests that the somatotopy of placebo analgesia relies on the creation of spatially guided expectations or conditioning, but can be maintained without ongoing monitoring of the affected body part...