Thomas M Link

Summary

Affiliation: University of Munich
Country: Germany

Publications

  1. ncbi request reprint High-resolution magnetic resonance imaging to assess trabecular bone structure in patients after transplantation: a review
    Thomas M Link
    Department of Radiology, Technische Universitat Munchen, Ismaninger Strasse 22, D 81675 Munich, Germany
    Top Magn Reson Imaging 13:365-75. 2002
  2. pmc Assessment of trabecular bone structure using MDCT: comparison of 64- and 320-slice CT using HR-pQCT as the reference standard
    Ahi S Issever
    Department of Radiology, Charite Campus Mitte, Universitaetsmedizin, Berlin, Germany
    Eur Radiol 20:458-68. 2010
  3. doi request reprint Assessment of trabecular bone structure of the calcaneus using multi-detector CT: correlation with microCT and biomechanical testing
    Gerd Diederichs
    Department of Radiology, Charite Universitatsmedizin Berlin, Charite Campus Mitte, Berlin, Germany
    Bone 44:976-83. 2009
  4. doi request reprint Cortical and trabecular bone structure analysis at the distal radius-prediction of biomechanical strength by DXA and MRI
    Thomas Baum
    Klinikum rechts der Isar, Institut fur Radiologie, Technische Universitat Munchen, Ismaninger Str 22, 81675, Munich, Germany
    J Bone Miner Metab 31:212-21. 2013
  5. doi request reprint Converted lumbar BMD values derived from sagittal reformations of contrast-enhanced MDCT predict incidental osteoporotic vertebral fractures
    Thomas Baum
    Institut fur Radiologie, Klinikum rechts der Isar, Technische Universitat Munchen, Ismaninger Str 22, 81675, Munich, Germany
    Calcif Tissue Int 90:481-7. 2012
  6. doi request reprint BMD measurements of the spine derived from sagittal reformations of contrast-enhanced MDCT without dedicated software
    Thomas Baum
    Institut für Röntgendiagnostik, Klinikum rechts der Isar, Technische Universitat Munchen, Ismaninger Str 22, 81675 Munchen, Germany
    Eur J Radiol 80:e140-5. 2011
  7. doi request reprint Prediction of bone strength by μCT and MDCT-based finite-element-models: How much spatial resolution is needed?
    Jan S Bauer
    Department of Radiology, Technische Universitat Munchen, Munich, Germany Department of Radiology, University of California, San Francisco, CA, United States Max Planck Institute for Extraterrestrial Physics, Garching, Germany Electronic address
    Eur J Radiol 83:e36-42. 2014
  8. doi request reprint Significance of sagittal reformations in routine thoracic and abdominal multislice CT studies for detecting osteoporotic fractures and other spine abnormalities
    Dirk Müller
    Department of Radiology, Klinikum rechts der Isar, TU Munchen, Ismaninger Str 22, 81675, Munchen, Germany
    Eur Radiol 18:1696-702. 2008
  9. ncbi request reprint Comparison of different radiography systems in an experimental study for detection of forearm fractures and evaluation of the Müller-AO and Frykman classification for distal radius fractures
    Stephan Metz
    Department of Diagnostic Radiology, Technical University of Munich, Ismaninger Strasse 22, 81675 Munich, Germany
    Invest Radiol 41:681-90. 2006
  10. doi request reprint Advances of 3T MR imaging in visualizing trabecular bone structure of the calcaneus are partially SNR-independent: analysis using simulated noise in relation to micro-CT, 1.5T MRI, and biomechanical strength
    Jan S Bauer
    Department of Radiology, Technische Universitat Munchen, Munich, Germany
    J Magn Reson Imaging 29:132-40. 2009

Collaborators

Detail Information

Publications45

  1. ncbi request reprint High-resolution magnetic resonance imaging to assess trabecular bone structure in patients after transplantation: a review
    Thomas M Link
    Department of Radiology, Technische Universitat Munchen, Ismaninger Strasse 22, D 81675 Munich, Germany
    Top Magn Reson Imaging 13:365-75. 2002
    ..In conclusion, structure measures determined in high-resolution magnetic resonance images may be useful in assessing changes of trabecular bone after organ transplantation and may improve the prediction of fracture risk...
  2. pmc Assessment of trabecular bone structure using MDCT: comparison of 64- and 320-slice CT using HR-pQCT as the reference standard
    Ahi S Issever
    Department of Radiology, Charite Campus Mitte, Universitaetsmedizin, Berlin, Germany
    Eur Radiol 20:458-68. 2010
    ..The aim of our study was to perform trabecular bone structure analysis with images from 64- and 320-slice multidetector computed tomography (MDCT) and to compare these with high-resolution peripheral computed tomography (HR-pQCT)...
  3. doi request reprint Assessment of trabecular bone structure of the calcaneus using multi-detector CT: correlation with microCT and biomechanical testing
    Gerd Diederichs
    Department of Radiology, Charite Universitatsmedizin Berlin, Charite Campus Mitte, Berlin, Germany
    Bone 44:976-83. 2009
    ..Multivariate models of BMD or structural parameters combined with texture indices improved prediction of bone strength significantly and might provide more reliable estimates of fracture risk in patients...
  4. doi request reprint Cortical and trabecular bone structure analysis at the distal radius-prediction of biomechanical strength by DXA and MRI
    Thomas Baum
    Klinikum rechts der Isar, Institut fur Radiologie, Technische Universitat Munchen, Ismaninger Str 22, 81675, Munich, Germany
    J Bone Miner Metab 31:212-21. 2013
    ....
  5. doi request reprint Converted lumbar BMD values derived from sagittal reformations of contrast-enhanced MDCT predict incidental osteoporotic vertebral fractures
    Thomas Baum
    Institut fur Radiologie, Klinikum rechts der Isar, Technische Universitat Munchen, Ismaninger Str 22, 81675, Munich, Germany
    Calcif Tissue Int 90:481-7. 2012
    ..In this longitudinal study, BMD values of the lumbar spine derived from sagittal reformations of routine abdominal contrast-enhanced MDCT predicted incidental osteoporotic vertebral fractures...
  6. doi request reprint BMD measurements of the spine derived from sagittal reformations of contrast-enhanced MDCT without dedicated software
    Thomas Baum
    Institut für Röntgendiagnostik, Klinikum rechts der Isar, Technische Universitat Munchen, Ismaninger Str 22, 81675 Munchen, Germany
    Eur J Radiol 80:e140-5. 2011
    ....
  7. doi request reprint Prediction of bone strength by μCT and MDCT-based finite-element-models: How much spatial resolution is needed?
    Jan S Bauer
    Department of Radiology, Technische Universitat Munchen, Munich, Germany Department of Radiology, University of California, San Francisco, CA, United States Max Planck Institute for Extraterrestrial Physics, Garching, Germany Electronic address
    Eur J Radiol 83:e36-42. 2014
    ..Thus, FEM were compared at decreasing resolutions with respect to local strain distribution and prediction of failure load to (1) validate MDCT-based FEM and to (2) optimize spatial resolution to save computation time...
  8. doi request reprint Significance of sagittal reformations in routine thoracic and abdominal multislice CT studies for detecting osteoporotic fractures and other spine abnormalities
    Dirk Müller
    Department of Radiology, Klinikum rechts der Isar, TU Munchen, Ismaninger Str 22, 81675, Munchen, Germany
    Eur Radiol 18:1696-702. 2008
    ..Sagittal reformations of standard MDCT images provide important additional information on spinal abnormalities; in particular, osteoporotic vertebral deformities are substantially better detected...
  9. ncbi request reprint Comparison of different radiography systems in an experimental study for detection of forearm fractures and evaluation of the Müller-AO and Frykman classification for distal radius fractures
    Stephan Metz
    Department of Diagnostic Radiology, Technical University of Munich, Ismaninger Strasse 22, 81675 Munich, Germany
    Invest Radiol 41:681-90. 2006
    ....
  10. doi request reprint Advances of 3T MR imaging in visualizing trabecular bone structure of the calcaneus are partially SNR-independent: analysis using simulated noise in relation to micro-CT, 1.5T MRI, and biomechanical strength
    Jan S Bauer
    Department of Radiology, Technische Universitat Munchen, Munich, Germany
    J Magn Reson Imaging 29:132-40. 2009
    ..5T and 3.0T and to specifically study noise effects on the visualization and quantification of trabecular architecture using conventional histomorphometric and nonlinear measures of bone structure...
  11. ncbi request reprint Reproducibility of trabecular bone structure measurements of the distal radius at 1.5 and 3.0 T magnetic resonance imaging
    Thomas Baum
    Institut fur Radiologie, Klinikum rechts der Isar, Technische Universitat Munchen, Munchen, Germany
    J Comput Assist Tomogr 36:623-6. 2012
    ..69% to 4.94% at 1.5 T MRI and from 0.38% to 5.80% at 3.0 T MRI. Thus, reproducibility errors of trabecular bone structure measurements are overall in an acceptable range and similar at 1.5 and 3.0 T MRI...
  12. doi request reprint Trabecular bone structure analysis of the spine using clinical MDCT: can it predict vertebral bone strength?
    Thomas Baum
    Institut fur Radiologie, Klinikum rechts der Isar, Technische Universitat Munchen, Ismaninger Str 22, 81675, Munich, Germany
    J Bone Miner Metab 32:56-64. 2014
    ..05). In this cadaver model, the spatial resolution of clinically available whole-body MDCT scanners was suitable for trabecular bone structure analysis of the spine and to predict vertebral bone strength. ..
  13. ncbi request reprint Improved performance of hip DXA using a novel region of interest in the upper part of the femoral neck: in vitro study using bone strength as a standard of reference
    Holger F Boehm
    Department of Diagnostic Radiology, LMU Muenchen, Germany
    J Clin Densitom 8:488-94. 2005
    ..Only a weak association was observed between failure load and FNAL...
  14. doi request reprint Magnetic resonance imaging of the ankle at 3.0 Tesla and 1.5 Tesla in human cadaver specimens with artificially created lesions of cartilage and ligaments
    Jan S Bauer
    Department of Radiology, Technical University, Munich, Germany
    Invest Radiol 43:604-11. 2008
    ..To compare magnetic resonance imaging of the ankle joint at 1.5 Tesla (T) and 3.0 T in the assessment of cartilage and ligament pathology in fresh human cadaver specimens...
  15. ncbi request reprint Normal and pathological MR findings in osteochondral autografts with longitudinal follow-up
    Thomas M Link
    Department of Radiology, Technische Universitat Munchen, Munich, Germany
    Eur Radiol 16:88-96. 2006
    ..Clinical and MR findings were not consistently associated in particular in the patients with osteochondral autograft necroses...
  16. doi request reprint Trabecular bone structure analysis in the osteoporotic spine using a clinical in vivo setup for 64-slice MDCT imaging: comparison to microCT imaging and microFE modeling
    Ahi S Issever
    Department of Radiology, Charite Campus Mitte, Universitaetsmedizin Berlin, Berlin, Germany
    J Bone Miner Res 24:1628-37. 2009
    ..However, when comparing with microFE-derived bone properties, BMD is superior compared with single parameters for microarchitecture, and correlations further improve when combining with texture measures...
  17. doi request reprint Do cartilage repair procedures prevent degenerative meniscus changes?: longitudinal t1ρ and morphological evaluation with 3.0-T MRI
    Pia M Jungmann
    Musculoskeletal and Quantitative Imaging Research, Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, California, USA
    Am J Sports Med 40:2700-8. 2012
    ..Cartilage repair (CR) procedures are widely accepted for treatment of isolated cartilage defects in the knee joint. However, it is not well known whether these procedures prevent degenerative joint disease...
  18. pmc Magnetic resonance imaging of ferumoxide-labeled mesenchymal stem cells in cartilage defects: in vitro and in vivo investigations
    Tobias D Henning
    Department of Radiology, University of Cologne, Cologne, Germany
    Mol Imaging 11:197-209. 2012
    ..The engraftment of iron oxide-labeled MASIs by simple incubation can be monitored over several weeks with MRI. Viable and apoptotic MASIs can be distinguished via imaging signs of cell proliferation at the transplantation site...
  19. ncbi request reprint Bone imaging: traditional techniques and their interpretation
    Holger F Boehm
    Department of Radiology, Technical University Muenchen, Ismaninger Strasse 22, 81375 Munich, Germany
    Curr Osteoporos Rep 2:41-6. 2004
    ..Quantitative ultrasound and structure analysis, based on high-resolution magnetic resonance imaging and computed tomography, are newer techniques in the diagnosis of osteoporosis that also focus on the assessment of bone structure...
  20. ncbi request reprint In vitro and in vivo spiral CT to determine bone mineral density: initial experience in patients at risk for osteoporosis
    Thomas M Link
    Department of Radiology, Klinikum rechts der Isar, Technische Universitaet, Munich, Germany
    Radiology 231:805-11. 2004
    ..To evaluate, both experimentally and in vivo, if nondedicated standard spiral computed tomography (CT) may be used to obtain reliable bone mineral density (BMD) data...
  21. ncbi request reprint Chest radiography with a digital flat-panel detector: experimental receiver operating characteristic analysis
    Stephan Metz
    Department of Diagnostic Radiology and Institute of Medical Statistics and Epidemiology, Technische Universitat Munchen, Ismaninger Str 22, 81675 Munich, Germany
    Radiology 234:776-84. 2005
    ....
  22. ncbi request reprint Comparison of 16-slice MSCT and MRI in the assessment of squamous cell carcinoma of the oral cavity
    Edzard Wiener
    Department of Diagnostic Radiology, University of Technology Munich, Ismaninger Str 22, D 81675 Munich, Germany
    Eur J Radiol 58:113-8. 2006
    ..4% versus 6.8% by MRI). Therefore, pre-operative MRI is recommended as the basic imaging modality of choice for treatment planning of oral SCC. MSCT is a valid alternative imaging method especially in cases with low patient compliance...
  23. ncbi request reprint Migration of iron oxide-labeled human hematopoietic progenitor cells in a mouse model: in vivo monitoring with 1.5-T MR imaging equipment
    Heike E Daldrup-Link
    Department of Radiology, Technical University, Munich, Germany
    Radiology 234:197-205. 2005
    ..To evaluate the use of clinical 1.5-T magnetic resonance (MR) imaging equipment to depict the in vivo distribution of iron oxide-labeled human hematopoietic progenitor cells in athymic mice...
  24. ncbi request reprint Assessment of vascular invasion in pancreatic head cancer with multislice spiral CT: value of multiplanar reconstructions
    Melanie Brügel
    Department of Radiology, Klinikum rechts der Isar, Technische Universitat Munchen, Ismaninger Strasse 22, 81675 Munich, Germany
    Eur Radiol 14:1188-95. 2004
    ..Thin-slice MPRs oriented perpendicularly to a possibly invaded vessel exactly depict the grade of circumferential involvement and thus have the capability to improve the assessment of vascular invasion in pancreatic cancer...
  25. ncbi request reprint Osteoporosis imaging
    Thomas M Link
    Department of Radiology, Technische Universitat Munchen, Ismaninger Strasse 22, Munich D 81675, Germany
    Radiol Clin North Am 41:813-39. 2003
    ..In this article the authors presented these standard techniques and newer diagnostic techniques that provide insights in the structure of trabecular bone...
  26. ncbi request reprint Imaging of trabecular bone structure
    Thomas M Link
    Department of Radiology, Klinikum rechts der Isar, Technische Universitat Munchen, Ismaninger Strasse 22, D 81675 Munich, Germany
    Semin Musculoskelet Radiol 6:253-61. 2002
    ..With the advances in magnetic resonance hardware and software and new CT techniques (i.e., multislice spiral CT and clinical micro-CT), noninvasive imaging of trabecular bone is becoming more feasible...
  27. ncbi request reprint The effects of geometric and threshold definitions on cortical bone metrics assessed by in vivo high-resolution peripheral quantitative computed tomography
    Kevin A Davis
    Department of Mechanical Engineering, University of California Berkeley, Berkeley, CA, USA
    Calcif Tissue Int 81:364-71. 2007
    ..Furthermore, while the direct 3D Ct.Th method is less sensitive to threshold effects, both methods are moderate predictors of mechanical strength, with the annular method being the stronger correlate...
  28. ncbi request reprint Fuzzy logic structure analysis of trabecular bone of the calcaneus to estimate proximal femur fracture load and discriminate subjects with and without vertebral fractures using high-resolution magnetic resonance imaging at 1.5 T and 3 T
    Priyesh V Patel
    Department of Radiology, University of California, San Francisco, CA 94143 0628, USA
    Calcif Tissue Int 81:294-304. 2007
    ..Local femoral measurements are still needed to estimate femoral bone strength. Overall, parameters obtained at 3.0 T performed better than those at 1.5 T...
  29. ncbi request reprint Bone structure of the distal radius and the calcaneus vs BMD of the spine and proximal femur in the prediction of osteoporotic spine fractures
    Thomas M Link
    Department of Clinical Radiology, University of Muenster, Muenster, Germany
    Eur Radiol 12:401-8. 2002
    ..A combination of BMD and structure measures did not yield any additional information on fracture status...
  30. ncbi request reprint Trabecular bone structure of the calcaneus: comparison of MR imaging at 3.0 and 1.5 T with micro-CT as the standard of reference
    Catherine M Phan
    Department of Radiology, University of California, San Francisco, 400 Parnassus Ave, A 367, Box 0628, San Francisco, CA 94143 0628, USA
    Radiology 239:488-96. 2006
    ..0-T MR imaging with that of 1.5-T MR imaging in differentiating donors with spinal fractures from those without spinal fractures...
  31. ncbi request reprint Determinants and heterogeneity of mechanical competence throughout the thoracolumbar spine of elderly women and men
    Felix Eckstein
    Department of Diagnostic Radiology, TU, Munchen, Germany
    Bone 35:364-74. 2004
    ..However, total density predicts functional segment failure stress with higher accuracy than (sub)cortical or trabecular density and is thus recommended for predicting fracture strength clinically...
  32. ncbi request reprint Trabecular bone structure of the distal radius, the calcaneus, and the spine: which site predicts fracture status of the spine best?
    Thomas M Link
    Department of Diagnostic Radiology, Technische Universitaet Muenchen, Munich, Germany
    Invest Radiol 39:487-97. 2004
    ....
  33. ncbi request reprint Sex differences of human trabecular bone microstructure in aging are site-dependent
    Felix Eckstein
    Institute of Anatomy and Musculoskeletal Research, Paracelsus Medical University, Salzburg, Austria
    J Bone Miner Res 22:817-24. 2007
    ..Significant sex differences are observed at the distal radius, femoral neck, and femoral trochanter, but not at the iliac crest, calcaneus, and lumbar vertebral body. Correlations in BV/TV between sites ranged from r = 0.13 to 0.56...
  34. ncbi request reprint Volumetric quantitative CT of the spine and hip derived from contrast-enhanced MDCT: conversion factors
    Jan S Bauer
    Department of Radiology, Technische Univerität München, Klinikum rechts der Isar, Institut für Roentgendiagnostik, Ismaninger Str 22, Munchen, Germany 81675
    AJR Am J Roentgenol 188:1294-301. 2007
    ....
  35. ncbi request reprint Trabecular bone structure obtained from multislice spiral computed tomography of the calcaneus predicts osteoporotic vertebral deformities
    Priyesh V Patel
    Chicago Medical School, North Chicago, IL, USA
    J Comput Assist Tomogr 29:246-53. 2005
    ....
  36. ncbi request reprint Reproducibility and side differences of mechanical tests for determining the structural strength of the proximal femur
    Felix Eckstein
    Musculoskeletal Research Group, Institute of Anatomy, Ludwig Maximilians Universitat, Munchen, Germany
    J Bone Miner Res 19:379-85. 2004
    ..Based on side differences in femoral failure loads in 55 pairs of femora, we estimated the upper limit of the precision error to be 15% for the side impact test, whereas the intersubject variability was >40%...
  37. ncbi request reprint Local differences in the trabecular bone structure of the proximal femur depicted with high-spatial-resolution MR imaging and multisection CT
    Ahi Sema Issever
    Magnetic Resonance Science Center, Department of Radiology, University of California, San Francisco, USA
    Acad Radiol 9:1395-406. 2002
    ..The authors performed this study to investigate structural variations in the trabecular bone of the proximal femur at high-resolution magnetic resonance (MR) imaging and high-resolution multisection computed tomography (CT)...
  38. ncbi request reprint Quantification of breast tumor microvascular permeability with feruglose-enhanced MR imaging: initial phase II multicenter trial
    Heike E Daldrup-Link
    Dept of Radiology, Univ Hosp, Technical Univ of Munich, Ismaningerstr 22, 81675 Munich, Germany
    Radiology 229:885-92. 2003
    ..To investigate use of the macromolecular contrast agent feruglose for differentiating and grading of human benign and malignant breast tumors on the basis of their microvascular characteristics...
  39. ncbi request reprint Characterization of trabecular bone structure from high-resolution magnetic resonance images using fuzzy logic
    Julio Carballido-Gamio
    MQIR, Department of Radiology, University of California, San Francisco, San Francisco, CA 94158, USA
    Magn Reson Imaging 24:1023-9. 2006
    ..85; P<.001) and good agreements based on Bland-Altman analysis, suggesting that the level of fuzziness in high-resolution magnetic resonance images could be related to the trabecular bone structure...
  40. ncbi request reprint Radiologic assessment of osteoporotic vertebral fractures: diagnostic and prognostic implications
    Thomas M Link
    Department of Radiology, University of California, San Francisco, 400 Parnassus Ave, A 367, P O Box 0628, San Francisco, CA, 94143 0628, USA
    Eur Radiol 15:1521-32. 2005
    ....
  41. ncbi request reprint Current diagnostic techniques in the evaluation of bone architecture
    Thomas M Link
    Department of Radiology, University of California, San Francisco, 400 Parnassus Avenue A 367, Box 0628, San Francisco, CA 94143, USA
    Curr Osteoporos Rep 2:47-52. 2004
    ..The methodologies described will include magnetic resonance imaging, clinical multislice spiral computed tomography, and micro-computed tomography, along with computerized analysis of radiographic patterns of trabecular bone...
  42. ncbi request reprint MR imaging of the ankle at 3 Tesla and 1.5 Tesla: protocol optimization and application to cartilage, ligament and tendon pathology in cadaver specimens
    Cameron Barr
    Department of Radiology, University of California San Francisco, San Francisco, CA, USA
    Eur Radiol 17:1518-28. 2007
    ..5 T and was significantly higher at 3.0 T for 2 out of 4 radiologists (p<0.05). Compared to 1.5 T, imaging of the ankle joint at 3.0 T significantly improved image quality and diagnostic performance in assessing cartilage pathology...
  43. doi request reprint Proximal femur specimens: automated 3D trabecular bone mineral density analysis at multidetector CT--correlation with biomechanical strength measurement
    Markus B Huber
    Musculoskeletal and Quantitative Imaging Research, Department of Radiology, University of California, San Francisco, 185 Berry St, Suite 350, San Francisco, CA 94107, USA
    Radiology 247:472-81. 2008
    ....
  44. ncbi request reprint Analysis of trabecular bone structure with multidetector spiral computed tomography in a simulated soft-tissue environment
    Jan S Bauer
    Musculoskeletal and Quantitative Imaging Research, Department of Radiology, University of California in San Francisco, San Francisco, CA, USA
    Calcif Tissue Int 80:366-73. 2007
    ..Even though ST scatter compromises image quality substantially, the major characteristics of the trabecular network can still be appreciated and quantified...
  45. ncbi request reprint Fast high-spatial-resolution MRI of the ankle with parallel imaging using GRAPPA at 3 T
    Jan Stefan Bauer
    Department of Radiology, University of California at San Francisco, San Francisco, CA, USA
    AJR Am J Roentgenol 189:240-5. 2007
    ..The purpose of our study was to compare an autocalibrating parallel imaging technique at 3 T with standard acquisitions at 3 and 1.5 T for small-field-of-view imaging of the ankle...