Research Topics
Species | D LichtermannSummaryAffiliation: University of Bonn Country: Germany Publications
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Detail Information
Publications
The genetic epidemiology of schizophrenia and of schizophrenia spectrum disordersD Lichtermann
Department of Psychiatry, University of Bonn, Germany
Eur Arch Psychiatry Clin Neurosci 250:304-10. 2000....- Pharmacogenomics and addiction to opiatesD Lichtermann
Department of Psychiatry, University of Bonn, Sigmund Freud Str 25, D 53105, Bonn, Germany
Eur J Pharmacol 410:269-279. 2000..The present state of pharmacogenomic and pharmacogenetic studies in animals and humans with respect to opiate addiction is reviewed in this paper... - Support for allelic association of a polymorphic site in the promoter region of the serotonin transporter gene with risk for alcohol dependenceD Lichtermann
Department of Psychiatry and Medical Psychology, University Medical School of Pecs, Hungary
Am J Psychiatry 157:2045-7. 2000..The authors sought additional evidence for this association from a family-based study... - Incidence of cancer among persons with schizophrenia and their relativesD Lichtermann
Department of Psychiatry, University of Bonn, Sigmund Freud Str 25, D 53105 Bonn, Germany
Arch Gen Psychiatry 58:573-8. 2001..Confirmation of these associations could lead to hypotheses on shared risk or protective factors, either genetic or environmental... - Concordance for sex and the pseudoautosomal gene hypothesis revisited: no evidence of increased sex concordance in a nationwide Finnish sample of siblings with paternally derived schizophreniaD Lichtermann
Department of Human Molecular Genetics, National Public Health Institute, Helsinki, Finland
Am J Psychiatry 155:1365-75. 1998.... - Linkage analysis of putative schizophrenia gene candidate regions on chromosomes 3p, 5q, 6p, 8p, 20p and 22q in a population-based sampled Finnish family setI Hovatta
Department of Human Molecular Genetics, National Public Health Institute, Helsinki, Finland
Mol Psychiatry 3:452-7. 1998..We were not able to find significant evidence for linkage on any of these chromosomal regions. However, some support for linkage was found on all studied chromosomal regions, except 3p... - Evaluation of linkage of bipolar affective disorder to chromosome 18 in a sample of 57 German familiesM M Nöthen
Institute of Human Genetics, University of Bonn, Germany
Mol Psychiatry 4:76-84. 1999..2 and 18q22-23 support prior evidence for susceptibility loci in these regions. The parent-of-origin effect on 18p11.2 is confirmed in our sample. The delineation of characteristics of 'either' families requires further study... 
Support for a chromosome 18p locus conferring susceptibility to functional psychoses in families with schizophrenia, by association and linkage analysisS G Schwab
Molecular Genetics Laboratory, Department of Psychiatry, University of Bon, Germany
Am J Hum Genet 63:1139-52. 1998..009). These results suggest the existence, on chromosome 18p, of a potential susceptibility locus for functional psychoses...- A possible susceptibility locus for bipolar affective disorder in chromosomal region 10q25--q26S Cichon
Institute of Human Genetics, University of Bonn, Wilhelmstr 31, D 53111 Bonn, Germany
Mol Psychiatry 6:342-9. 2001..12 (P = 0.0013). Positive linkage findings that have been reported by two independent studies further support the hypothesis of a susceptibility gene for bipolar affective disorder on 10q25-q26... - Recurrent brief depression in general practice. Clinical features, comorbidity with other disorders, and need for treatmentW Maier
Department of Psychiatry, University of Mainz, Germany
Eur Arch Psychiatry Clin Neurosci 244:196-204. 1994..This new diagnostic category needs more attention as only as small minority of patients with RBD received specific antidepressant treatment... - hSKCa3: no association of the polymorphic CAG repeat with bipolar affective disorder and schizophreniaT Rohrmeier
Department of Psychiatry, University of Regensburg, Germany
Psychiatr Genet 9:169-75. 1999..Thus, our data do not support the hypothesis that longer CAG repeats in the hSkCa3 gene contribute to the susceptibility for bipolar disorder and schizophrenia... - Human delta-opioid receptor gene and susceptibility to heroin and alcohol dependenceP Franke
Department of Psychiatry, University of Bonn, Bonn, Germany
Am J Med Genet 88:462-4. 1999..Our results, therefore, do not support an association between genetic variation of the delta-opioid receptor and addictive behavior in man... - Association study of the low-activity allele of catechol-O-methyltransferase and alcoholism using a family-based approachT Wang
Institute of Human Genetics, University of Bonn, Wilhelmstr 31, 53111 Bonn, Germany
Mol Psychiatry 6:109-11. 2001..83, P = 0.028). Our results provide further evidence for an involvement of the COMT low-activity allele in the development of alcoholism and demonstrate the need for further studies in large samples of alcoholic patients... - A genome screen for genes predisposing to bipolar affective disorder detects a new susceptibility locus on 8qS Cichon
Institute of Human Genetics, University of Bonn, Wilhelmstrasse 31, D 53111 Bonn, Germany
Hum Mol Genet 10:2933-44. 2001..Putative paternally imprinted loci were identified in chromosomal regions 2p24-p21 and 2q31-q32. Maternally imprinted susceptibility genes may be located on 14q32 and 16q21-q23... - Brief depression among patients in general practice. Prevalence and variation by recurrence and severityW Maier
Department of Psychiatry, University of Mainz, Germany
Eur Arch Psychiatry Clin Neurosci 244:190-5. 1994..The diagnostic definition of RBD has a major impact on the sex ratio of cases: the less restrictive the diagnosis, the more balanced are the prevalence rates between males and females... - Genome-wide scan for schizophrenia in the Finnish population: evidence for a locus on chromosome 7q22J Ekelund
Department of Human Molecular Genetics, National Public Health Institute, Helsinki, Finland
Hum Mol Genet 9:1049-57. 2000..Our data demonstrate the importance of genealogical information for studies aiming at identification of predisposing loci in complex diseases... - The impact of gender and age at onset on the familial aggregation of schizophreniaW Maier
Department of Psychiatry, University of Mainz, Germany
Eur Arch Psychiatry Clin Neurosci 242:279-85. 1993..Affective disorders occurred in families independently of the probands' gender. Aetiological heterogeneity or ascertainment bias may account for the modifying effect of proband's gender in schizophrenia... - A large population cohort provides normative data for investigation of temperamentJ Miettunen
Department of Psychiatry, Oulu University, Oulu University Hospital, Oulu, Finland
Acta Psychiatr Scand 110:150-7. 2004..We simultaneously compared the properties of the temperament dimensions of the Tridimensional Personality Questionnaire (TPQ) and of the Temperament and Character Inventory (TCI)... - Identification of two novel polymorphisms and a rare deletion variant in the human dopamine D4 receptor geneS Cichon
Institute of Human Genetics, University of Bonn, Germany
Psychiatr Genet 5:97-103. 1995..We were unable to detect the deletion in patients with schizophrenia and bipolar affective disorder, nor in healthy controls...