Philipp Lichte

Summary

Affiliation: University Hospital
Country: Germany

Publications

  1. doi request reprint Increased in-hospital mortality following severe head injury in young children: results from a nationwide trauma registry
    Philipp Lichte
    Department of Orthopaedic Trauma Surgery, University Hospital Aachen, Pauwelsstrase 30, 52074, Aachen, Germany
    Eur J Med Res 20:65. 2015
  2. doi request reprint Inhalative IL-10 treatment after bilateral femoral fractures affect pulmonary inflammation in mice
    Philipp Lichte
    Department of Orthopaedic Trauma Surgery, Harald Tscherne Lab for Orthopedic Research, Pauwelsstraβe 30, Aachen, Germany Electronic address
    Ann Anat 200:73-8. 2015
  3. doi request reprint Post-traumatic thrombo-embolic complications in polytrauma patients
    Philipp Lichte
    Department of Orthopaedic Trauma Surgery, University Hospital Aachen, Pauwelsstrase 30, 52074, Aachen, Germany
    Int Orthop 39:947-54. 2015
  4. pmc Dehydroepiandrosterone modulates the inflammatory response in a bilateral femoral shaft fracture model
    Philipp Lichte
    Department of Orthopaedic Trauma Surgery, Faculty of Medicine, RWTH Aachen University, Pauwelsstraβe 30, Aachen 52074, Germany
    Eur J Med Res 19:27. 2014
  5. doi request reprint Low dose LPS does not increase TLR4 expression on monocytes in a human in vivo model
    Philipp Lichte
    Department of Orthopaedic Trauma Surgery, Medical School of the RWTH Aachen, Pauwelsstr 30, 52074 Aachen, Germany
    Cytokine 63:74-80. 2013
  6. doi request reprint Scaffolds for bone healing: concepts, materials and evidence
    P Lichte
    Department of Trauma Surgery, University Hospital of the RWTH Aachen, Aachen, Germany
    Injury 42:569-73. 2011
  7. pmc A civilian perspective on ballistic trauma and gunshot injuries
    Philipp Lichte
    Department of Trauma Surgery, University Hospital of the RWTH Aachen, Aachen, Germany
    Scand J Trauma Resusc Emerg Med 18:35. 2010
  8. doi request reprint Detecting severe injuries of the upper body in multiple trauma patients
    Klemens Horst
    Department for Orthopaedic Trauma, RWTH Aachen University Hospital, Aachen, Germany Electronic address
    J Surg Res 199:629-34. 2015
  9. doi request reprint Increased morbidity and mortality after bilateral femoral shaft fractures: myth or reality in the era of damage control?
    Philipp Kobbe
    Department of Orthopaedic Trauma Surgery, University Hospital RWTH Aachen, Germany
    Injury 44:221-5. 2013
  10. doi request reprint Models of hemorrhagic shock: differences in the physiological and inflammatory response
    Roman Pfeifer
    Department of Orthopaedics and Trauma Surgery, Aachen University Medical Center, Aachen, Germany
    Cytokine 61:585-90. 2013

Detail Information

Publications21

  1. doi request reprint Increased in-hospital mortality following severe head injury in young children: results from a nationwide trauma registry
    Philipp Lichte
    Department of Orthopaedic Trauma Surgery, University Hospital Aachen, Pauwelsstrase 30, 52074, Aachen, Germany
    Eur J Med Res 20:65. 2015
    ..The aim of our study was to verify the in-hospital outcome of different paediatric age groups in comparison to adults with respect to the treatment strategy...
  2. doi request reprint Inhalative IL-10 treatment after bilateral femoral fractures affect pulmonary inflammation in mice
    Philipp Lichte
    Department of Orthopaedic Trauma Surgery, Harald Tscherne Lab for Orthopedic Research, Pauwelsstraβe 30, Aachen, Germany Electronic address
    Ann Anat 200:73-8. 2015
    ..We sought to investigate the effect of inhalative IL-10 administration on the systemic and pulmonary inflammatory response in a small animal model of bilateral femoral fracture...
  3. doi request reprint Post-traumatic thrombo-embolic complications in polytrauma patients
    Philipp Lichte
    Department of Orthopaedic Trauma Surgery, University Hospital Aachen, Pauwelsstrase 30, 52074, Aachen, Germany
    Int Orthop 39:947-54. 2015
    ..Our aim was to determine the incidence of arterial and venous thrombo-embolic events (TE) in severely-injured trauma patients, and its associated risk factors by using a large trauma registry...
  4. pmc Dehydroepiandrosterone modulates the inflammatory response in a bilateral femoral shaft fracture model
    Philipp Lichte
    Department of Orthopaedic Trauma Surgery, Faculty of Medicine, RWTH Aachen University, Pauwelsstraβe 30, Aachen 52074, Germany
    Eur J Med Res 19:27. 2014
    ..The present study analyzes whether DHEA is also involved in the mediation of inflammatory stimuli induced by bilateral femoral shaft fracture...
  5. doi request reprint Low dose LPS does not increase TLR4 expression on monocytes in a human in vivo model
    Philipp Lichte
    Department of Orthopaedic Trauma Surgery, Medical School of the RWTH Aachen, Pauwelsstr 30, 52074 Aachen, Germany
    Cytokine 63:74-80. 2013
    ..The aim of this human in vivo study was to investigate the expression of TLR4 and CD11b on the surface of human monocytes after in vivo low-dose LPS stimulation...
  6. doi request reprint Scaffolds for bone healing: concepts, materials and evidence
    P Lichte
    Department of Trauma Surgery, University Hospital of the RWTH Aachen, Aachen, Germany
    Injury 42:569-73. 2011
    ..Calcium phosphate ceramics show similar properties to bone and are degradable. Different modifications can improve the bioactive features. This article gives an overview about the current materials and their evidence of clinical use...
  7. pmc A civilian perspective on ballistic trauma and gunshot injuries
    Philipp Lichte
    Department of Trauma Surgery, University Hospital of the RWTH Aachen, Aachen, Germany
    Scand J Trauma Resusc Emerg Med 18:35. 2010
    ..Gunshot injuries in civilians have more focal injury patterns and should be considered distinct entities...
  8. doi request reprint Detecting severe injuries of the upper body in multiple trauma patients
    Klemens Horst
    Department for Orthopaedic Trauma, RWTH Aachen University Hospital, Aachen, Germany Electronic address
    J Surg Res 199:629-34. 2015
    ..We hypothesized that clavicular fracture in polytrauma patients would indicate the presence of further injuries of the upper extremities, head, neck, and thorax...
  9. doi request reprint Increased morbidity and mortality after bilateral femoral shaft fractures: myth or reality in the era of damage control?
    Philipp Kobbe
    Department of Orthopaedic Trauma Surgery, University Hospital RWTH Aachen, Germany
    Injury 44:221-5. 2013
    ..The objective of this study was to compare the incidence of morbidity and mortality in patients with bilateral vs. unilateral femoral shaft fractures in the era of damage control orthopaedics...
  10. doi request reprint Models of hemorrhagic shock: differences in the physiological and inflammatory response
    Roman Pfeifer
    Department of Orthopaedics and Trauma Surgery, Aachen University Medical Center, Aachen, Germany
    Cytokine 61:585-90. 2013
    ..The aim of this study was to compare the inflammatory response of different established protocols for volume-controlled shock in a murine model...
  11. pmc Plate osteosynthesis versus hemiarthroplasty in proximal humerus fractures--does routine screening of systemic inflammatory biomarkers makes sense?
    Klemens Horst
    Department of Orthopaedics and Trauma Surgery, Aachen University Medical Centre, Pauwelsstrasse 30, 52074, Aachen, Germany
    Eur J Med Res 20:5. 2015
    ..This study investigated CRP and WBC serum levels after osteosynthesis or hemiarthroplasty of humeral head fractures...
  12. pmc Inhalative IL-10 attenuates pulmonary inflammation following hemorrhagic shock without major alterations of the systemic inflammatory response
    Philipp Kobbe
    Department of Orthopaedic Trauma Surgery, Faculty of Medicine, RWTH Aachen University, Pauwelsstraβe 30, 52074 Aachen, Germany
    Mediators Inflamm 2012:512974. 2012
    ....
  13. pmc MALP-2 pre-treatment modulates systemic inflammation in hemorrhagic shock
    Roman Pfeifer
    Department of Orthopaedic Trauma Surgery, RWTH Aachen University, Pauwelsstrasse 30, 52074 Aachen, Germany
    J Inflamm (Lond) 10:17. 2013
    ..In this experiment we investigated whether immunostimulation with TLR-2 agonists under conditions of sterile inflammation (hemorrhagic shock (HS)) may affect the immune response and remote organ inflammation...
  14. pmc Low back pain during pregnancy caused by a sacral stress fracture: a case report
    Miguel Pishnamaz
    Department of Orthopedic and Trauma Surgery, University of Aachen Medical Center, 30 Pauwels Street, 52074 Aachen, Germany
    J Med Case Rep 6:98. 2012
    ..abstract:..
  15. doi request reprint Impaired Fracture Healing after Hemorrhagic Shock
    Philipp Lichte
    Harald Tscherne Research Laboratory for Orthopedic Trauma, Department of Orthopaedic Trauma Surgery, University Hospital RWTH Aachen, Pauwelsstrase 30, 52074 Aachen, Germany
    Mediators Inflamm 2015:132451. 2015
    ..This may be due to significantly diminished osteoclast recruitment. The exact mechanisms should be studied further, particularly during earlier stages of fracture healing. ..
  16. pmc Predictors of poor outcome after both column acetabular fractures: a 30-year retrospective cohort study
    Philipp Lichte
    Department of Orthopaedic Trauma Surgery, Medical School of the RWTH Aachen, Aachen, Germany
    Patient Saf Surg 7:9. 2013
    ....
  17. pmc Socio-economic outcome after blunt orthopaedic trauma: Implications on injury prevention
    Roman Pfeifer
    University of Aachen Medical Center, Department of Orthopaedic Trauma, Pauwelsstrase 30, 52074 Aachen, Germany
    Patient Saf Surg 5:9. 2011
    ..abstract:..
  18. doi request reprint Lipopolysaccharide-induced experimental immune activation does not impair memory functions in humans
    Jan Sebastian Grigoleit
    Institute of Medical Psychology and Behavioral Immunobiology, University Hospital Essen, University of Duisburg Essen, 45122 Essen, Germany
    Neurobiol Learn Mem 94:561-7. 2010
    ..However, these changes in immune and neuroendocrine parameters were not associated with alterations of memory performance, selective attention or executive functions...
  19. doi request reprint Damage control orthopedics: current evidence
    Philipp Lichte
    Department of Orthopaedic Trauma Surgery, Medical School of the RWTH Aachen University, Aachen, Germany
    Curr Opin Crit Care 18:647-50. 2012
    ..This review gives an overview of the current literature concerning this important question in the treatment of severely injured patients...
  20. doi request reprint Effects of near cortical slotted holes in locking plate constructs
    Richard Martin Sellei
    Department of Orthopaedic Trauma, University of Aachen Medical Center, Aachen, Germany
    J Orthop Trauma 25:S35-40. 2011
    ..Slotted near cortical locking holes might improve this drawback. This review summarizes the current knowledge of the healing process associated with different types of near cortical locking options...
  21. doi request reprint Complex extremity fractures following high energy injuries: the limited value of existing classifications and a proposal for a treatment-guide
    Philipp Kobbe
    Department of Orthopaedic and Trauma Surgery, University Hospital Aachen, Aachen, Germany
    Injury 40:S69-74. 2009
    ..In selected cases, primary amputation is a life-saving alternative. We present a new treatment guide taking parameters of local injury severity into account...