I Leuschner

Summary

Affiliation: University of Kiel
Country: Germany

Publications

  1. doi request reprint [Lipofibromatosis in a 6-year-old girl: a case report]
    I Leuschner
    Kindertumorregister der Gesellschaft für Pädiatrische Onkologie und Hämatologie GPOH, Sektion Kinderpathologie, Institut fur Pathologie, Universitatsklinikum Schleswig Holstein, Campus Kiel, Michaelisstr 11, 24105 Kiel
    Pathologe 31:150-2. 2010
  2. ncbi request reprint p53 and mdm-2 expression in Rhabdomyosarcoma of childhood and adolescence: clinicopathologic study by the Kiel Pediatric Tumor Registry and the German Cooperative Soft Tissue Sarcoma Study
    Ivo Leuschner
    Department of Pathology, Kiel Paediatric Tumor Registry, Institute for Paediatric Pathology, University of Kiel, Michaelisstrasse 11, D 24105 Kiel, Germany
    Pediatr Dev Pathol 6:128-36. 2003
  3. ncbi request reprint Rhabdomyosarcoma of the urinary bladder and vagina: a clinicopathologic study with emphasis on recurrent disease: a report from the Kiel Pediatric Tumor Registry and the German CWS Study
    I Leuschner
    Kiel Pediatric Tumor Registry, Institute for Pediatric Pathology, University of Kiel, Germany
    Am J Surg Pathol 25:856-64. 2001
  4. doi request reprint [Histological findings in an irradiated choroidal melanoma]
    S Koinzer
    Klinik für Ophthalmologie, UK SH Campus Kiel, Arnold Heller Strasse 3, Kiel, Germany
    Ophthalmologe 108:570-4. 2011
  5. doi request reprint [A rare tumour of the auricle]
    C Werner
    Klinik fur Hals, Nasen, Ohrenheilkunde, Kopf und Halschirurgie, Christian Albrechts Universitat zu Kiel, Arnold Heller Straße 3, Haus 27, 24105, Kiel, Germany
    HNO 59:61-3. 2011
  6. ncbi request reprint Combretastatin A-4 prodrug: a potent inhibitor of malignant hemangioendothelioma cell proliferation
    A S Böhle
    Department of General Surgery and Thoracic Surgery, Christian Albrechts University, Kiel, Germany
    Int J Cancer 87:838-43. 2000
  7. ncbi request reprint An improved orthotopic xenotransplant procedure for human lung cancer in SCID bg mice
    A S Boehle
    Department of General Surgery, Christian Albrechts University Hospital, Kiel, Germany
    Ann Thorac Surg 69:1010-5. 2000
  8. ncbi request reprint Artificial neural network analysis (ANNA) of prostatic transrectal ultrasound
    T Loch
    Klinik für Urologie der Christian Albrechts Universität, Kiel, Germany
    Prostate 39:198-204. 1999
  9. doi request reprint [Extended sentinel lymph node dissection in radical prostatectomy for prostate cancer: a study in the Kiel risk population]
    S Hautmann
    Klinik für Urologie und Kinderurologie, Universitatsklinikum Schleswig Holstein, Campus Kiel, Kiel, Germany
    Urologe A 47:299-303. 2008
  10. doi request reprint [Inflammatory myofibroblastic tumor]
    I Leuschner
    Kindertumorregister der Gesellschaft für Pädiatrische Onkologie und Hämatologie GPOH, Sektion Kinderpathologie, Institut fur Pathologie, Universitatsklinikum Schleswig Holstein, Campus Kiel, Michaelisstr 11, 24105 Kiel
    Pathologe 31:106-8. 2010

Collaborators

Detail Information

Publications20

  1. doi request reprint [Lipofibromatosis in a 6-year-old girl: a case report]
    I Leuschner
    Kindertumorregister der Gesellschaft für Pädiatrische Onkologie und Hämatologie GPOH, Sektion Kinderpathologie, Institut fur Pathologie, Universitatsklinikum Schleswig Holstein, Campus Kiel, Michaelisstr 11, 24105 Kiel
    Pathologe 31:150-2. 2010
    ..The lesion showed a typical fascicular growth patter into the fatty tissue. Differential diagnosis includes fibrous hamartoma of infancy. Lipofibromatosis is a benign disease but recurrences are not unusual...
  2. ncbi request reprint p53 and mdm-2 expression in Rhabdomyosarcoma of childhood and adolescence: clinicopathologic study by the Kiel Pediatric Tumor Registry and the German Cooperative Soft Tissue Sarcoma Study
    Ivo Leuschner
    Department of Pathology, Kiel Paediatric Tumor Registry, Institute for Paediatric Pathology, University of Kiel, Michaelisstrasse 11, D 24105 Kiel, Germany
    Pediatr Dev Pathol 6:128-36. 2003
    ..In conclusion, we could not demonstrate that any of the investigated parameters had an influence on prognosis of RMS. p53 protein overexpression might be a crucial step in metastatic disease for patients with embryonal RMS...
  3. ncbi request reprint Rhabdomyosarcoma of the urinary bladder and vagina: a clinicopathologic study with emphasis on recurrent disease: a report from the Kiel Pediatric Tumor Registry and the German CWS Study
    I Leuschner
    Kiel Pediatric Tumor Registry, Institute for Pediatric Pathology, University of Kiel, Germany
    Am J Surg Pathol 25:856-64. 2001
    ..Maturation after chemotherapy occurs frequently in RMS. In contrast to the excellent prognosis reported in other studies, we had two patients with fatal outcome despite chemotherapy-induced maturation in the recurrences...
  4. doi request reprint [Histological findings in an irradiated choroidal melanoma]
    S Koinzer
    Klinik für Ophthalmologie, UK SH Campus Kiel, Arnold Heller Strasse 3, Kiel, Germany
    Ophthalmologe 108:570-4. 2011
    ..Histological findings of choroidal melanomas after proton beam irradiation have been reported for complicated cases after enucleation. We present specimens of a tumor after transretinal probe excision...
  5. doi request reprint [A rare tumour of the auricle]
    C Werner
    Klinik fur Hals, Nasen, Ohrenheilkunde, Kopf und Halschirurgie, Christian Albrechts Universitat zu Kiel, Arnold Heller Straße 3, Haus 27, 24105, Kiel, Germany
    HNO 59:61-3. 2011
    ..Grading of these tumours can be challenging since benign as well as malign phenotypes have been described. Therefore, beside complete resection of the lesion additional radiotherapy should be discussed individually...
  6. ncbi request reprint Combretastatin A-4 prodrug: a potent inhibitor of malignant hemangioendothelioma cell proliferation
    A S Böhle
    Department of General Surgery and Thoracic Surgery, Christian Albrechts University, Kiel, Germany
    Int J Cancer 87:838-43. 2000
    ..in vivo, CA-4PD induces extensive intratumoral cell loss within 24 hr following systemic administration, suggesting a synergistic effect of direct cell killing and the induction of vascular shutdown...
  7. ncbi request reprint An improved orthotopic xenotransplant procedure for human lung cancer in SCID bg mice
    A S Boehle
    Department of General Surgery, Christian Albrechts University Hospital, Kiel, Germany
    Ann Thorac Surg 69:1010-5. 2000
    ..Overall prognosis in human lung cancer is still poor. A highly reproducible, easy to perform in vivo model, which closely resembles the clinical features of advanced human lung cancer, is required for the evaluation of novel therapies...
  8. ncbi request reprint Artificial neural network analysis (ANNA) of prostatic transrectal ultrasound
    T Loch
    Klinik für Urologie der Christian Albrechts Universität, Kiel, Germany
    Prostate 39:198-204. 1999
    ..After training with this pathologically confirmed digitized TRUS information, ANNA was tested in a blinded study...
  9. doi request reprint [Extended sentinel lymph node dissection in radical prostatectomy for prostate cancer: a study in the Kiel risk population]
    S Hautmann
    Klinik für Urologie und Kinderurologie, Universitatsklinikum Schleswig Holstein, Campus Kiel, Kiel, Germany
    Urologe A 47:299-303. 2008
    ..Further studies will show whether these numbers will hold true in patients undergoing radical prostatectomy for prostate cancer...
  10. doi request reprint [Inflammatory myofibroblastic tumor]
    I Leuschner
    Kindertumorregister der Gesellschaft für Pädiatrische Onkologie und Hämatologie GPOH, Sektion Kinderpathologie, Institut fur Pathologie, Universitatsklinikum Schleswig Holstein, Campus Kiel, Michaelisstr 11, 24105 Kiel
    Pathologe 31:106-8. 2010
    ..ALK is expressed in approximately 50% of tumors. The tumors are associated with a benign behavior but recurrences occur in about one third of abdominal cases. Malignant cases are rare...
  11. ncbi request reprint Desmoplastic small round cell tumor
    I Leuschner
    Department of Pediatric Pathology, Kiel Pediatric Tumor Registry, University of Kiel, Germany
    Semin Diagn Pathol 13:204-12. 1996
    ..The involvement of the WT1 and EWS genes in the translocation makes this tumor an interesting subject for research on histogenesis and differentiation in small round and blue cell tumors...
  12. ncbi request reprint [Emergent treatment of a malignant peripheral epineurial tumour]
    C Schafmayer
    Klinik für Allgemeine Chirurgie und Thoraxchirurgie, Universitatsklinikum Schleswig Holstein, Campus Kiel, Kiel
    Chirurg 77:633-6. 2006
    ..Chemotherapy was carried out due to a G2 tumour classification. The patient is currently undergoing rehabilitation, during which the peripheral neurological deficits are improving gradually...
  13. ncbi request reprint Overexpression of phosphatidylinositol 3-kinase in human lung cancer
    X Lin
    Department of General and Thoracic Surgery, University of Kiel, Arnold Heller Strasse 7, 24105 Kiel, Germany
    Langenbecks Arch Surg 386:293-301. 2001
    ..This study was conducted to investigate the expression of phosphatidylinositol 3-kinase (PI3K) and AKT2, a downstream effector, in primary human lung carcinomas of different histological type...
  14. ncbi request reprint [Childhood kidney tumors -- the relevance of imaging]
    J P Schenk
    Abteilung Pädiatrische Radiologie, Universitätsklinik Heidelberg
    Radiologe 45:1112-23. 2005
    ..In summary, diagnostic imaging in renal tumors in children plays a role in differential diagnosis, staging, monitoring of therapy, and surgical planning...
  15. ncbi request reprint [MRI-morphology and staging of congenital mesoblastic nephroma: evaluation of a collection with 20 patients]
    J P Schenk
    Abt Päd Radiologie Universitätsklinik Heidelberg, Im Neuenheimer Feld 153, 69120 Heidelberg
    Rofo 177:1373-9. 2005
    ..To differentiate classic and cellular type of congenital mesoblastic nephroma (CMN) in MRI and to evaluate MRI for staging according to the Societe Internationale de Oncologie Pediatrique (SIOP)...
  16. ncbi request reprint Teratoma with malignant transformation: experiences of the cooperative GPOH protocols MAKEI 83/86/89/96
    W Biskup
    Department of Pediatric Oncology, Hematology and Immunology, Children s Hospital, UKD, Heinrich Heine University, Dusseldorf
    Klin Padiatr 218:303-8. 2006
    ..While TMT is a rare but well recognised phenomenon in adult germ cell tumors (GCT), data on TMT in pediatric GCTs are lacking...
  17. ncbi request reprint Identification of various exon combinations of the ews/fli1 translocation: an optimized RT-PCR method for paraffin embedded tissue -- a report by the CWS-study group
    S Stegmaier
    Olgahospital, Stuttgart, Germany
    Klin Padiatr 216:315-22. 2004
    ..This conflicts with the requirement for identification of various possible exon combinations by PCR simultaneously using one single primer pair with larger distance...
  18. ncbi request reprint Results of the SIOP 93-01/GPOH trial and study for the treatment of patients with unilateral nonmetastatic Wilms Tumor
    H Reinhard
    Klinik für Päd Onkologie und Hämatologie, Universitätsklinik für Kinder und Jugendmedizin, Homburg, Germany
    Klin Padiatr 216:132-40. 2004
    ..In contrast to the National Wilms Tumor Study Group (NWTSG) the SIOP trials and studies largely focus on the issue of preoperative therapy to facilitate surgery of a shrunken tumor and to treat metastasis as early as possible...
  19. ncbi request reprint Survival in nephroblastoma treated according to the trial and study SIOP-9/GPOH with respect to relapse and morbidity
    A Weirich
    Department of Pediatric Oncology, University of Heidelberg, Im Neuenheimer Feld 150, D 69120 Heidelberg, Germany
    Ann Oncol 15:808-20. 2004
    ..Recent Wilms' tumor (WT) trials and studies have tried to determine the minimal therapy needed for cure. The goal was survival without morbidity...
  20. ncbi request reprint [Decreased number of R1-resections in radical retropubic prostatectomy. Use of a newly developed fast sectioning technique]
    P M Braun
    Klinik für Urologie und Kinderurologie, Universitatsklinikum Schleswig Holstein, Campus Kiel
    Urologe A 44:1324-31. 2005
    ..2%, P < or =0.001). Our results demonstrate that the new frozen margin technique is clearly more sensitive for intraoperative detection of positive margins and thus leads to substantially higher rates of negative surgical margins...