Research Topics
| I LeuschnerSummaryAffiliation: University of Kiel Country: Germany Publications
| Collaborators
|
Detail Information
Publications
[Lipofibromatosis in a 6-year-old girl: a case report]I Leuschner
Kindertumorregister der Gesellschaft für Pädiatrische Onkologie und Hämatologie GPOH, Sektion Kinderpathologie, Institut fur Pathologie, Universitatsklinikum Schleswig Holstein, Campus Kiel, Michaelisstr 11, 24105 Kiel
Pathologe 31:150-2. 2010..The lesion showed a typical fascicular growth patter into the fatty tissue. Differential diagnosis includes fibrous hamartoma of infancy. Lipofibromatosis is a benign disease but recurrences are not unusual...
p53 and mdm-2 expression in Rhabdomyosarcoma of childhood and adolescence: clinicopathologic study by the Kiel Pediatric Tumor Registry and the German Cooperative Soft Tissue Sarcoma StudyIvo Leuschner
Department of Pathology, Kiel Paediatric Tumor Registry, Institute for Paediatric Pathology, University of Kiel, Michaelisstrasse 11, D 24105 Kiel, Germany
Pediatr Dev Pathol 6:128-36. 2003..In conclusion, we could not demonstrate that any of the investigated parameters had an influence on prognosis of RMS. p53 protein overexpression might be a crucial step in metastatic disease for patients with embryonal RMS...- Rhabdomyosarcoma of the urinary bladder and vagina: a clinicopathologic study with emphasis on recurrent disease: a report from the Kiel Pediatric Tumor Registry and the German CWS StudyI Leuschner
Kiel Pediatric Tumor Registry, Institute for Pediatric Pathology, University of Kiel, Germany
Am J Surg Pathol 25:856-64. 2001..Maturation after chemotherapy occurs frequently in RMS. In contrast to the excellent prognosis reported in other studies, we had two patients with fatal outcome despite chemotherapy-induced maturation in the recurrences... - [Histological findings in an irradiated choroidal melanoma]S Koinzer
Klinik für Ophthalmologie, UK SH Campus Kiel, Arnold Heller Strasse 3, Kiel, Germany
Ophthalmologe 108:570-4. 2011..Histological findings of choroidal melanomas after proton beam irradiation have been reported for complicated cases after enucleation. We present specimens of a tumor after transretinal probe excision... - [A rare tumour of the auricle]C Werner
Klinik fur Hals, Nasen, Ohrenheilkunde, Kopf und Halschirurgie, Christian Albrechts Universitat zu Kiel, Arnold Heller Straße 3, Haus 27, 24105, Kiel, Germany
HNO 59:61-3. 2011..Grading of these tumours can be challenging since benign as well as malign phenotypes have been described. Therefore, beside complete resection of the lesion additional radiotherapy should be discussed individually... - Combretastatin A-4 prodrug: a potent inhibitor of malignant hemangioendothelioma cell proliferationA S Böhle
Department of General Surgery and Thoracic Surgery, Christian Albrechts University, Kiel, Germany
Int J Cancer 87:838-43. 2000..in vivo, CA-4PD induces extensive intratumoral cell loss within 24 hr following systemic administration, suggesting a synergistic effect of direct cell killing and the induction of vascular shutdown... - An improved orthotopic xenotransplant procedure for human lung cancer in SCID bg miceA S Boehle
Department of General Surgery, Christian Albrechts University Hospital, Kiel, Germany
Ann Thorac Surg 69:1010-5. 2000..Overall prognosis in human lung cancer is still poor. A highly reproducible, easy to perform in vivo model, which closely resembles the clinical features of advanced human lung cancer, is required for the evaluation of novel therapies... - Artificial neural network analysis (ANNA) of prostatic transrectal ultrasoundT Loch
Klinik für Urologie der Christian Albrechts Universität, Kiel, Germany
Prostate 39:198-204. 1999..After training with this pathologically confirmed digitized TRUS information, ANNA was tested in a blinded study... - [Extended sentinel lymph node dissection in radical prostatectomy for prostate cancer: a study in the Kiel risk population]S Hautmann
Klinik für Urologie und Kinderurologie, Universitatsklinikum Schleswig Holstein, Campus Kiel, Kiel, Germany
Urologe A 47:299-303. 2008..Further studies will show whether these numbers will hold true in patients undergoing radical prostatectomy for prostate cancer... - [Inflammatory myofibroblastic tumor]I Leuschner
Kindertumorregister der Gesellschaft für Pädiatrische Onkologie und Hämatologie GPOH, Sektion Kinderpathologie, Institut fur Pathologie, Universitatsklinikum Schleswig Holstein, Campus Kiel, Michaelisstr 11, 24105 Kiel
Pathologe 31:106-8. 2010..ALK is expressed in approximately 50% of tumors. The tumors are associated with a benign behavior but recurrences occur in about one third of abdominal cases. Malignant cases are rare... - Desmoplastic small round cell tumorI Leuschner
Department of Pediatric Pathology, Kiel Pediatric Tumor Registry, University of Kiel, Germany
Semin Diagn Pathol 13:204-12. 1996..The involvement of the WT1 and EWS genes in the translocation makes this tumor an interesting subject for research on histogenesis and differentiation in small round and blue cell tumors... - [Emergent treatment of a malignant peripheral epineurial tumour]C Schafmayer
Klinik für Allgemeine Chirurgie und Thoraxchirurgie, Universitatsklinikum Schleswig Holstein, Campus Kiel, Kiel
Chirurg 77:633-6. 2006..CONCLUSION: This rare case of a malignant peripheral epineurial tumour with acute symptoms demonstrates the ability of hospitals with maximum care facilities to maintain services even in times of financial cuts in health care services... - Overexpression of phosphatidylinositol 3-kinase in human lung cancerX Lin
Department of General and Thoracic Surgery, University of Kiel, Arnold Heller Strasse 7, 24105 Kiel, Germany
Langenbecks Arch Surg 386:293-301. 2001..This study was conducted to investigate the expression of phosphatidylinositol 3-kinase (PI3K) and AKT2, a downstream effector, in primary human lung carcinomas of different histological type... - [Childhood kidney tumors -- the relevance of imaging]J P Schenk
Abteilung Pädiatrische Radiologie, Universitätsklinik Heidelberg
Radiologe 45:1112-23. 2005..In summary, diagnostic imaging in renal tumors in children plays a role in differential diagnosis, staging, monitoring of therapy, and surgical planning... - [MRI-morphology and staging of congenital mesoblastic nephroma: evaluation of a collection with 20 patients]J P Schenk
Abt Päd Radiologie Universitätsklinik Heidelberg, Im Neuenheimer Feld 153, 69120 Heidelberg
Rofo 177:1373-9. 2005..To differentiate classic and cellular type of congenital mesoblastic nephroma (CMN) in MRI and to evaluate MRI for staging according to the Societe Internationale de Oncologie Pediatrique (SIOP)... - Teratoma with malignant transformation: experiences of the cooperative GPOH protocols MAKEI 83/86/89/96W Biskup
Department of Pediatric Oncology, Hematology and Immunology, Children s Hospital, UKD, Heinrich Heine University, Dusseldorf
Klin Padiatr 218:303-8. 2006..While TMT is a rare but well recognised phenomenon in adult germ cell tumors (GCT), data on TMT in pediatric GCTs are lacking... - Identification of various exon combinations of the ews/fli1 translocation: an optimized RT-PCR method for paraffin embedded tissue -- a report by the CWS-study groupS Stegmaier
Olgahospital, Stuttgart, Germany
Klin Padiatr 216:315-22. 2004..This conflicts with the requirement for identification of various possible exon combinations by PCR simultaneously using one single primer pair with larger distance... - Results of the SIOP 93-01/GPOH trial and study for the treatment of patients with unilateral nonmetastatic Wilms TumorH Reinhard
Klinik für Päd Onkologie und Hämatologie, Universitätsklinik für Kinder und Jugendmedizin, Homburg, Germany
Klin Padiatr 216:132-40. 2004..In contrast to the National Wilms Tumor Study Group (NWTSG) the SIOP trials and studies largely focus on the issue of preoperative therapy to facilitate surgery of a shrunken tumor and to treat metastasis as early as possible... - Survival in nephroblastoma treated according to the trial and study SIOP-9/GPOH with respect to relapse and morbidityA Weirich
Department of Pediatric Oncology, University of Heidelberg, Im Neuenheimer Feld 150, D 69120 Heidelberg, Germany
Ann Oncol 15:808-20. 2004..Recent Wilms' tumor (WT) trials and studies have tried to determine the minimal therapy needed for cure. The goal was survival without morbidity... - [Decreased number of R1-resections in radical retropubic prostatectomy. Use of a newly developed fast sectioning technique]P M Braun
, , Campus Kiel
Urologe A 44:1324-31. 2005..2%, P < or =0.001). Our results demonstrate that the new frozen margin technique is clearly more sensitive for intraoperative detection of positive margins and thus leads to substantially higher rates of negative surgical margins...