Miriam Lenhard

Summary

Affiliation: University of Munich
Country: Germany

Publications

  1. ncbi request reprint Immunosuppressive Glycodelin A is an independent marker for poor prognosis in endometrial cancer
    Miriam Lenhard
    Department of Obstetrics and Gynecology, Ludwig Maximilians University Munich, Campus Grosshadern, Marchioninistr, 15, 81377 Munich, Germany
    BMC Cancer 13:616. 2013
  2. pmc Steroid hormone receptor expression in ovarian cancer: progesterone receptor B as prognostic marker for patient survival
    Miriam Lenhard
    Department of Obstetrics and Gynecology, Grosshadern Campus, Ludwig Maximilians University Hospital, Marchioninistrasse 15, Munich 81377, Germany
    BMC Cancer 12:553. 2012
  3. ncbi request reprint The diagnostic accuracy of two human epididymis protein 4 (HE4) testing systems in combination with CA125 in the differential diagnosis of ovarian masses
    Miriam Lenhard
    Department of Obstetrics and Gynecology, Ludwig Maximilians University Munich, Grosshadern Campus, Munich, Germany
    Clin Chem Lab Med 49:2081-8. 2011
  4. pmc Human chorionic gonadotropin and its relation to grade, stage and patient survival in ovarian cancer
    Miriam Lenhard
    Department of Obstetrics and Gynecology, Grosshadern Campus, Ludwig Maximilians University Hospital, Munich, Germany
    BMC Cancer 12:2. 2012
  5. doi request reprint Relapse and survival in early-stage ovarian cancer
    S Miriam Lenhard
    Department of Obstetrics and Gynecology, Ludwig Maximilians University Munich, Campus Grosshadern, Marchioninistrasse 15, Munich 80337, Germany
    Arch Gynecol Obstet 280:71-7. 2009
  6. doi request reprint Long-term follow-up after ovarian borderline tumor: relapse and survival in a large patient cohort
    Miriam S Lenhard
    Department of Obstetrics and Gynecology, Ludwig Maximilians University Munich, Campus Grosshadern, Munich, Germany
    Eur J Obstet Gynecol Reprod Biol 145:189-94. 2009
  7. doi request reprint Predictive value of CA 125 and CA 72-4 in ovarian borderline tumors
    Miriam S Lenhard
    Department of Obstetrics and Gynecology, Ludwig Maximilians University Munich, Campus Grosshadern, Munich, Germany
    Clin Chem Lab Med 47:537-42. 2009
  8. ncbi request reprint PET-CT in recurrent ovarian cancer: impact on treatment planning
    Miriam S Lenhard
    Department of Obstetrics and Gynecology, Ludwig Maximilians University Munich, Campus Grosshadem, Munich, Germany
    Anticancer Res 28:2303-8. 2008
  9. doi request reprint Predictive value of PET-CT imaging versus AGO-scoring in patients planned for cytoreductive surgery in recurrent ovarian cancer
    S M Lenhard
    Department of Obstetrics and Gynecology, Ludwig Maximilians University Munich, Campus Grosshadern, Marchioninistrasse 15, 80337 Munich, Germany
    Eur J Obstet Gynecol Reprod Biol 140:263-8. 2008
  10. doi request reprint Breast cancer and pregnancy: challenges of chemotherapy
    Miriam S Lenhard
    Department of Obstetrics and Gynecology, Campus Grosshadern, Ludwig Maximilians University of Munich, Marchioninistrasse 15, 80337 Munich, Germany
    Crit Rev Oncol Hematol 67:196-203. 2008

Detail Information

Publications35

  1. ncbi request reprint Immunosuppressive Glycodelin A is an independent marker for poor prognosis in endometrial cancer
    Miriam Lenhard
    Department of Obstetrics and Gynecology, Ludwig Maximilians University Munich, Campus Grosshadern, Marchioninistr, 15, 81377 Munich, Germany
    BMC Cancer 13:616. 2013
    ..The aim of this study was to assess Glycodelin (Gd) and its immunosuppressive isoform Glycodelin A (GdA) in endometrial cancer tissue and to analyze its impact on clinical and pathological features and patient outcome...
  2. pmc Steroid hormone receptor expression in ovarian cancer: progesterone receptor B as prognostic marker for patient survival
    Miriam Lenhard
    Department of Obstetrics and Gynecology, Grosshadern Campus, Ludwig Maximilians University Hospital, Marchioninistrasse 15, Munich 81377, Germany
    BMC Cancer 12:553. 2012
    ..The aim of this study was to assess the expression of the receptor isoforms ER-α/-β and PR-A/-B in OC tissue and to analyze its impact on clinical and pathological features and patient outcome...
  3. ncbi request reprint The diagnostic accuracy of two human epididymis protein 4 (HE4) testing systems in combination with CA125 in the differential diagnosis of ovarian masses
    Miriam Lenhard
    Department of Obstetrics and Gynecology, Ludwig Maximilians University Munich, Grosshadern Campus, Munich, Germany
    Clin Chem Lab Med 49:2081-8. 2011
    ..Cancer antigen 125 (CA125) is the best known single tumor marker for ovarian cancer (OC). We investigated whether the additional information of the human epididymis protein 4 (HE4) improves diagnostic accuracy...
  4. pmc Human chorionic gonadotropin and its relation to grade, stage and patient survival in ovarian cancer
    Miriam Lenhard
    Department of Obstetrics and Gynecology, Grosshadern Campus, Ludwig Maximilians University Hospital, Munich, Germany
    BMC Cancer 12:2. 2012
    ....
  5. doi request reprint Relapse and survival in early-stage ovarian cancer
    S Miriam Lenhard
    Department of Obstetrics and Gynecology, Ludwig Maximilians University Munich, Campus Grosshadern, Marchioninistrasse 15, Munich 80337, Germany
    Arch Gynecol Obstet 280:71-7. 2009
    ..To analyze the prognostic influence of patient characteristics, diagnostic markers or therapeutic procedures in women diagnosed with early ovarian cancer based on relapse and survival in long term follow-up...
  6. doi request reprint Long-term follow-up after ovarian borderline tumor: relapse and survival in a large patient cohort
    Miriam S Lenhard
    Department of Obstetrics and Gynecology, Ludwig Maximilians University Munich, Campus Grosshadern, Munich, Germany
    Eur J Obstet Gynecol Reprod Biol 145:189-94. 2009
    ..To assess long-term survival and relapse rate of patients diagnosed with a borderline tumor of the ovary (BOT) with special focus on the influence of primary surgery...
  7. doi request reprint Predictive value of CA 125 and CA 72-4 in ovarian borderline tumors
    Miriam S Lenhard
    Department of Obstetrics and Gynecology, Ludwig Maximilians University Munich, Campus Grosshadern, Munich, Germany
    Clin Chem Lab Med 47:537-42. 2009
    ..The aim of this study was to assess the prognostic value of cancer antigen (CA) 125 and CA 72-4 in patients with ovarian borderline tumor (BOT)...
  8. ncbi request reprint PET-CT in recurrent ovarian cancer: impact on treatment planning
    Miriam S Lenhard
    Department of Obstetrics and Gynecology, Ludwig Maximilians University Munich, Campus Grosshadem, Munich, Germany
    Anticancer Res 28:2303-8. 2008
    ..Positron emission tomography-computed tomography (PET-CT) is currently not established in the management of recurrent ovarian cancer. Here, its value in diagnosis and therapy planning was evaluated...
  9. doi request reprint Predictive value of PET-CT imaging versus AGO-scoring in patients planned for cytoreductive surgery in recurrent ovarian cancer
    S M Lenhard
    Department of Obstetrics and Gynecology, Ludwig Maximilians University Munich, Campus Grosshadern, Marchioninistrasse 15, 80337 Munich, Germany
    Eur J Obstet Gynecol Reprod Biol 140:263-8. 2008
    ..To assess the predictive value of positron emission tomography computed tomography (PET-CT) imaging in comparison to AGO-scoring in patients planned for cytoreductive surgery in recurrent ovarian cancer...
  10. doi request reprint Breast cancer and pregnancy: challenges of chemotherapy
    Miriam S Lenhard
    Department of Obstetrics and Gynecology, Campus Grosshadern, Ludwig Maximilians University of Munich, Marchioninistrasse 15, 80337 Munich, Germany
    Crit Rev Oncol Hematol 67:196-203. 2008
    ..As evidence-based data on diagnostics and treatment is lacking, current recommendations mostly derive from nonrandomized experiences. We reviewed the current literature with focus on chemotherapy during pregnancy and lactation...
  11. ncbi request reprint Phyllodes tumour of the breast: clinical follow-up of 33 cases of this rare disease
    Miriam S Lenhard
    Department of Obstetrics and Gynecology, University Hospital Munich, Ludwig Maximilians University of Munich, Grosshadern, Marchioninistrasse 15, Munich, Germany
    Eur J Obstet Gynecol Reprod Biol 138:217-21. 2008
    ..The "cystosarcoma phyllodes" of the breast is a rare entity which accounts for 0.5% of all breast neoplasms. The aim of our study was to analyse the clinical management with respect to patient outcome...
  12. ncbi request reprint Use of novel serum markers in clinical follow-up of Sertoli-Leydig cell tumours
    Miriam Lenhard
    Department of Obstetrics and Gynaecology, Campus Grosshadern, Ludwig Maximilians University, Munich, Germany
    Clin Chem Lab Med 45:657-61. 2007
    ..Sertoli-Leydig cell tumours of the ovary account for only 0.2% of malignant ovarian tumours. Two-thirds of all patients become apparent due to the tumour's hormone production...
  13. ncbi request reprint Obstetrical and gynecological writing and publishing in Europe
    Miriam S Lenhard
    Department of Obstetrics and Gynecology, Ludwig Maximilians University Munich, Campus Grosshadern, Marchioninistrasse 15, 81377 Munich, Germany
    Eur J Obstet Gynecol Reprod Biol 129:119-23. 2006
    ..To assess the number and quality of scientific articles published by authors from the European Union (EU) and Germany in the field of obstetrics and gynecology...
  14. ncbi request reprint The high-grade endometrial sarcoma: a rare entity
    S M Lenhard
    Department of Obstetrics and Gynecology, Ludwig Maximilians University Munich, Campus Grosshadern, Marchioninistrasse 15, 80337, Munich, Germany
    Arch Gynecol Obstet 274:56-9. 2006
    ..It is subclassified into a high-grade and a prognostically better low-grade type. Evidence-based data for a standardized therapy is lacking...
  15. ncbi request reprint Three-dimensional pelvimetry by computed tomography
    M Lenhard
    Department of Obstetrics and Gynecology, Ludwig Maximilians University Munich, Campus Grosshadern, Munich, Germany
    Radiol Med 114:827-34. 2009
    ..This study was undertaken to assess the agreement of computed tomography (CT) pelvimetry with different postprocessing techniques...
  16. ncbi request reprint Nelfinavir induces the unfolded protein response in ovarian cancer cells, resulting in ER vacuolization, cell cycle retardation and apoptosis
    Ansgar Brüning
    University Hospital Munich, Department of Obstetrics Gynecology, Maistrasse 11, München 80337, Germany
    Cancer Biol Ther 8:226-32. 2009
    ..Because nelfinavir represents an already approved drug for use in humans with HIV infection, it could rapidly be tested in clinical studies as a potential treatment strategy against drug-resistant ovarian cancer...
  17. pmc The G-protein coupled estrogen receptor (GPER/GPR30) is a gonadotropin receptor dependent positive prognosticator in ovarian carcinoma patients
    Sabine Heublein
    Department of Obstetrics and Gynaecology, Campus Innenstadt, Ludwig Maximilians University of Munich, Munich, Germany
    PLoS ONE 8:e71791. 2013
    ..Further studies are needed to evaluate the impact of GPER activation on a clinical scheme...
  18. pmc Glycodelin A is a prognostic marker to predict poor outcome in advanced stage ovarian cancer patients
    Christoph Scholz
    Department of Obstetrics and Gynecology, Heinrich Heine University, Dusseldorf, Germany
    BMC Res Notes 5:551. 2012
    ..Further the use of Glycodelin as a serum marker in benign and malignant ovarian diseases was evaluated...
  19. ncbi request reprint Human epididymis protein 4 (HE4) in benign and malignant diseases
    Linda Hertlein
    Department of Obstetrics and Gynecology, University ofMunich, Campus Grosshadern, Munich, Germany
    Clin Chem Lab Med 50:2181-8. 2012
    ....
  20. ncbi request reprint Inducers of G-protein coupled estrogen receptor (GPER) in endometriosis: potential implications for macrophages and follicle maturation
    Sabine Heublein
    Department of Obstetrics and Gynaecology, Campus Innenstadt, Ludwig Maximilians University of Munich, Munich, Germany
    J Reprod Immunol 97:95-103. 2013
    ..The multiple roles of GPER as presented herein make it a promising future candidate for targeted molecular endometriosis treatment...
  21. ncbi request reprint Thyroid hormone receptor (TR)alpha and TRbeta expression in breast cancer
    Nina Ditsch
    Department of Obstetrics and Gynecology Großhadern, Ludwig Maximilians University, Munich, Germany
    Histol Histopathol 28:227-37. 2013
    ..Discussion: Our results revealed specific alterations in the expression of TRs - especially of TRalpha2 - in breast cancer patients, suggesting it as a marker with possible prognostic validity...
  22. doi request reprint Bortezomib treatment of ovarian cancer cells mediates endoplasmic reticulum stress, cell cycle arrest, and apoptosis
    Ansgar Brüning
    Department of Obstetrics Gynecology, University Hospital Munich, Maistrasse 11, 80337, Munich, Germany
    Invest New Drugs 27:543-51. 2009
    ..However, a combination treatment with taxanes may not be beneficial and may even be less effective...
  23. doi request reprint Cetuximab monotherapy in advanced cervical cancer: a retrospective study with five patients
    Linda Hertlein
    Department of Obstetrics and Gynecology, Ludwig Maximilians University Munich, Campus Grosshadern, Marchioninistrasse 15, Munich, Germany
    Arch Gynecol Obstet 283:109-13. 2011
    ..In cervical cancer the expression of EGFR is reported in up to 85% of the tumour cells. Therefore, Cetuximab monotherapy could be a new option in the treatment of patients with advanced cervical cancer...
  24. pmc The association between vitamin D receptor expression and prolonged overall survival in breast cancer
    Nina Ditsch
    Department of Obstetrics and Gynecology Großhadern, Ludwig Maximilians University, Munich, Germany
    J Histochem Cytochem 60:121-9. 2012
    ..The present data suggest that VDR expression in breast cancer tissue may be of clinical significance, and the results provide evidence that VDR may be a factor with prognostic relevance...
  25. ncbi request reprint Staining of MUC1 in ovarian cancer tissues with PankoMab-GEX detecting the tumour-associated epitope, TA-MUC1, as compared to antibodies HMFG-1 and 115D8
    Darius Dian
    Department of Obstetrics and Gynecology, Ludwig Maximilians University Munich, Munich, Germany
    Histol Histopathol 28:239-44. 2013
    ..The findings are encouraging with respect to a potential use of PankoMab-GEX as a new therapeutic antibody for the treatment of ovarian cancer patients...
  26. pmc Mucin-1 and its relation to grade, stage and survival in ovarian carcinoma patients
    Verena Engelstaedter
    Department of Obstetrics and Gynaecology, University of Cologne, Kerpener Straße 34, Cologne, 50931, Germany
    BMC Cancer 12:600. 2012
    ..29. Another aim of this study was to evaluate Mucin-1 expression by immunohistochemistry in a different cohort of ovarian carcinoma patients with respect to grade, stage and survival...
  27. pmc Her-2/neu expression is a negative prognosticator in ovarian cancer cases that do not express the follicle stimulating hormone receptor (FSHR)
    Sabine Heublein
    Department of Obstetrics and Gynaecology Campus Innenstadt, Ludwig Maximilians University of Munich, Maistrasse 11, 80337, Munich, Germany
    J Ovarian Res 6:6. 2013
    ..abstract:..
  28. doi request reprint A retrospective investigation of women's experience with breast reconstruction after mastectomy
    Nina Ditsch
    Department of Obstetrics and Gynaecology, Breast Center, Ludwig Maximilians University, Campus Grosshadern, Marchioninistr 15, 81377 Munich, Germany
    Arch Gynecol Obstet 287:555-61. 2013
    ..Hence, many patients opt for reconstructive surgery. This study evaluated the effects of different types of reconstructive surgery after mastectomy on the functional and psychological adjustment of patients...
  29. ncbi request reprint KRAS, BRAF genotyping reveals genetic heterogeneity of ovarian borderline tumors and associated implants
    Sabine Heublein
    Department of Pathology, Ludwig Maximilians University of Munich, Munich, Germany
    BMC Cancer 13:483. 2013
    ..It remains obscure whether these implants actually resemble metastasis owning the same genetic pattern as the ovarian primary or whether they develop independently...
  30. doi request reprint Malnutrition and clinical outcome in gynecologic patients
    Linda Hertlein
    Department of Obstetrics and Gynecology, University of Munich Campus Grosshadern, Munich, Germany Electronic address
    Eur J Obstet Gynecol Reprod Biol 174:137-40. 2014
    ..Therefore an assessment of malnutrition is needed to detect malnourished patients in gynecology and initiate nutritional therapy if needed...
  31. doi request reprint The G-protein-coupled estrogen receptor (GPER) is expressed in normal human ovaries and is upregulated in ovarian endometriosis and pelvic inflammatory disease involving the ovary
    Sabine Heublein
    Department of Obstetrics and Gynaecology, Ludwig Maximilians University of Munich, Munich, Germany
    Reprod Sci 19:1197-204. 2012
    ..Moreover, GPER was upregulated in ovarian endometriosis and PID. Overexpression of GPER in both inflammation and endometriosis affecting the ovary may prove useful in explaining/predicting the main endometriosis-related symptoms...
  32. doi request reprint Nelfinavir induces TRAIL receptor upregulation in ovarian cancer cells
    Ansgar Brüning
    University Hospital Munich, Department of Obstetrics Gynecology, Maistrasse 11, 80337 Munich, Germany
    Biochem Biophys Res Commun 377:1309-14. 2008
    ....
  33. ncbi request reprint Images in cardiovascular medicine. Detection of cardiac metastasis by positron-emission tomography-computed tomography
    Thorsten R C Johnson
    Department of Clinical Radiology, University of Munich, Munich, Germany
    Circulation 112:e61-2. 2005
  34. ncbi request reprint Material differentiation by dual energy CT: initial experience
    Thorsten R C Johnson
    Department of Clinical Radiology, University of Munich Grosshadern Campus, Marchioninistrasse 15, 81377 Munich, Germany
    Eur Radiol 17:1510-7. 2007
    ..Dual energy CT offers a more specific tissue characterization in CT and can improve the assessment of vascular disease. Further studies are required to draw conclusions on the diagnostic value of the individual applications...
  35. ncbi request reprint Thyroid function in breast cancer patients
    Nina Ditsch
    Department of Obstetrics and Gynecology Grosshadern, Ludwig Maximilians University, Munich, Germany
    Anticancer Res 30:1713-7. 2010
    ..In addition, oestrogen-like effects of thyroid hormones on breast cancer cell growth are seen in vitro. Therefore, this study evaluated thyroid function in breast cancer patients, women with benign breast tumour and healthy controls...