Research Topics
| M R LemkeSummaryAffiliation: University of Kiel Country: Germany Publications
| Collaborators
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Detail Information
Publications
Depression and Parkinson's diseaseMatthias R Lemke
Rhine Clinic Bonn, Kaiser Karl Ring 20, 53111 Bonn, Germany
J Neurol 251:VI/24-7. 2004..New dopamine agonists pramipexole and ropinirole appear to ameliorate depressive symptoms in PD in addition to effects on motor symptoms. There is a lack of appropriate rating scales and controlled studies regarding depression in PD...
Motor activity and perception of sleep in depressed patientsM R Lemke
Department of Psychiatry, University of Kiel, Germany
J Psychiatr Res 33:215-24. 1999..The results warrant further controlled studies to evaluate the role of psychological factors for objective measurements and subjective perception of sleep patterns...
Temporal segmentation of human short-term behavior in everyday activities and interview sessionsM R Lemke
Klinik fur Psychiatrie und Psychotherapie, Christian Albrechts Universitat, Kiel, Germany
Naturwissenschaften 86:289-92. 1999..This method could be a promising tool to investigate time patterns of movements and psychomotor alterations in psychiatric patients during interview sessions...
Timing of movements in depressed patients and healthy controlsM R Lemke
Department of Psychiatry, Christian Albrechts University of Kiel, Germany
J Affect Disord 56:209-14. 1999..Timing may depend on cognitive and emotional functions which are affected in depression. Therefore, time structure of action units in depressed patients was compared to healthy controls...
Segmentation of behavior and time structure of movements in depressed patientsM R Lemke
Department of Psychiatry, Christian Albrechts University of Kiel, Germany
Psychopathology 33:131-6. 2000..Altered time structure of movements represents an observable psychopathological sign and may be relevant for pathophysiological and behavioral aspects in depression...
Spatiotemporal gait patterns during over ground locomotion in major depression compared with healthy controlsM R Lemke
Department of Psychiatry, University of Kiel, D 24105 Kiel, Germany
J Psychiatr Res 34:277-83. 2000..The results may indicate possible deficiencies in the motor control system in depression. These first results about alterations of spatiotemporal gait patterns in depression warrant further longitudinal and experimental studies...
[Disordered behavioral control in psychiatric illnesses. Neurophysiological aspects of impulsive behavior]M R Lemke
Klinik fur Psychiatrie und Psychotherapie, Klinikum der Christian Albrechts Universität zu Kiel, Niemannsweg 147, 24105 Kiel
Nervenarzt 72:342-6. 2001..Because new techniques enable objective assessment of behavior generation and execution, the current knowledge about neurophysiological aspects of behavioral control is summarized...
[Motor behavior in depression: applications and limitations of actigraphic analyses]M R Lemke
Klinik fur Psychiatrie und Psychotherapie, Christian Albrechts Universitat zu Kiel
Psychiatr Prax 28:219-25. 2001..Functions and application of actigraphy and empirical findings in depression will be summarised and discussed...
Effect of reboxetine on depression in Parkinson's disease patientsMatthias R Lemke
Department of Psychiatry University of Kiel, Germany
J Clin Psychiatry 63:300-4. 2002..The efficacy of reboxetine, a novel norepinephrine reuptake inhibitor, has been shown in major depressive disorder, with specific effects on motivation and negligible effects on psychomotor and cognitive function...
Early improvement as a predictor of remission and response in schizophrenia: Results from a naturalistic studyM Jager
Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
Eur Psychiatry 24:501-6. 2009..To examine the predictive validity of early improvement in a naturalistic sample of inpatients and to identify the criterion that best defines early improvement...
Time course of antipsychotic treatment response in schizophrenia: results from a naturalistic study in 280 patientsM Jager
Department of Psychiatry, Ludwig Maximilians University, Nussbaumstr 7, D 80336 Munich, Germany
Schizophr Res 118:183-8. 2010..To describe the course of positive and negative symptoms during inpatient treatment and examine remission and response rates under routine clinical care conditions...
Dopamine agonists in the treatment of non-motor symptoms of Parkinson's disease: depressionM R Lemke
Department of Psychiatry, University of Kiel, Kliniken Alsterdorf, Hamburg, Germany
Eur J Neurol 15:9-14. 2008..Depressive symptoms in patients with PD are a major complication that impairs quality of life independent of motor symptoms. The relationship between PD and comorbid depression is not completely understood...
Depressive symptoms in Parkinson's diseaseM R Lemke
Department of Psychiatry, University of Kiel, Kiel, Germany
Eur J Neurol 15:21-5. 2008..Because of the data available as well as clinical reasoning, pramipexole may be used as a first-line treatment in patients with PD and depression...
Standardized remission criteria in schizophrenia: descriptive validity and comparability with previously used outcome measuresM Jager
Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
Pharmacopsychiatry 41:190-5. 2008..Standardized consensus criteria for remission in schizophrenia were recently proposed. As yet, the validity of these criteria and their comparability with previously used outcome measures are unclear...
Effects of the dopamine agonist pramipexole on depression, anhedonia and motor functioning in Parkinson's diseaseMatthias R Lemke
Center of Psychiatry and Neurology, Rhine Clinic Bonn, Germany
J Neurol Sci 248:266-70. 2006..Drop-outs due to adverse events occurred in 3.5%. Future studies should investigate specificity of anti-anhedonic and antidepressive properties of pramipexole...
Anhedonia, depression, and motor functioning in Parkinson's disease during treatment with pramipexoleMatthias R Lemke
Center of Psychiatry and Neurology, Rhine Clinic Bonn, Germany
J Neuropsychiatry Clin Neurosci 17:214-20. 2005..Future studies should further investigate antianhedonic efficacy of dopamine agonists including pramipexole in depressed patients with Parkinson's disease...
Psychopathological characteristics and treatment response of first episode compared with multiple episode schizophrenic disordersMarkus Jager
Department of Psychiatry, Ludwig Maximilians University, Nussbaumstr 7, D 80336 Munich, Germany
Eur Arch Psychiatry Clin Neurosci 257:47-53. 2007..The aim was to investigate the hypothesis that patients with first episode schizophrenic disorders have a more favorable treatment response than those with multiple episodes...
Suicide attempts in schizophrenia and affective disorders with relation to some specific demographical and clinical characteristicsDaniel J Muller
Centre for Addiction and Mental Health, Neurogenetics Section, University of Toronto, 250 College Street, M5T 1R8 Toronto, ON, Canada
Eur Psychiatry 20:65-9. 2005..Suicide attempts were associated with poor premorbid social adjustment, low age at onset, low scores on the "Global Assessment Scale" and childlessness in females...
