B Langguth

Summary

Affiliation: University of Regensburg
Country: Germany

Publications

  1. pmc Transcranial magnetic stimulation for the treatment of tinnitus: effects on cortical excitability
    Berthold Langguth
    Department of Psychiatry, Psychosomatics and Psychotherapy, University of Regensburg, Regensburg, Germany
    BMC Neurosci 8:45. 2007
  2. pmc The revolving door phenomenon revisited: time to readmission in 17'415 patients with 37'697 hospitalisations at a German psychiatric hospital
    Ulrich Frick
    Department of Psychiatry and Psychotherapy, University of Regensburg, Regensburg, Germany Döpfer University of Applied Sciences, Department of Psychology, Cologne, Germany Research Institute on Public Health and Addiction, University of Zurich, Zurich, Switzerland
    PLoS ONE 8:e75612. 2013
  3. pmc Neuroimaging and neuromodulation: complementary approaches for identifying the neuronal correlates of tinnitus
    Berthold Langguth
    Department of Psychiatry and Psychotherapy, University of Regensburg Regensburg, Germany
    Front Syst Neurosci 6:15. 2012
  4. doi request reprint Tinnitus: therapeutic use of superficial brain stimulation
    Berthold Langguth
    Interdisciplinary Tinnitus Clinic, Department of Psychiatry and Psychotherapy, University of Regensburg, Regensburg, Germany Electronic address
    Handb Clin Neurol 116:441-67. 2013
  5. pmc Regensburg Insomnia Scale (RIS): a new short rating scale for the assessment of psychological symptoms and sleep in insomnia; study design: development and validation of a new short self-rating scale in a sample of 218 patients suffering from insomnia and
    Tatjana Crönlein
    Department of Psychiatry and Psychotherapy, University Regensburg, Universitaetsstrasse 84, Regensburg 93042, Germany
    Health Qual Life Outcomes 11:65. 2013
  6. pmc Tinnitus assessment by means of standardized self-report questionnaires: psychometric properties of the Tinnitus Questionnaire (TQ), the Tinnitus Handicap Inventory (THI), and their short versions in an international and multi-lingual sample
    Florian Zeman
    Center for Clinical Studies, University Hospital Regensburg, Regensburg, 93042, Germany
    Health Qual Life Outcomes 10:128. 2012
  7. pmc Linking the Tinnitus Questionnaire and the subjective Clinical Global Impression: which differences are clinically important?
    Ilya Adamchic
    Institute of Neuroscience and Medicine Neuromodulation, Research Center Julich, Leo Brand Straße, 52425, Julich, Germany
    Health Qual Life Outcomes 10:79. 2012
  8. pmc Sexually dimorphic effects of oxytocin receptor gene (OXTR ) variants on Harm Avoidance
    Trayana Stankova
    Department of Psychiatry and Psychotherapy, University of Regensburg, Universitaetsstrasse 84, 93053 Regensburg, Germany
    Biol Sex Differ 3:17. 2012
  9. pmc Mindfulness-and body-psychotherapy-based group treatment of chronic tinnitus: a randomized controlled pilot study
    Peter M Kreuzer
    Department of Psychiatry and Psychotherapy, University of Regensburg, Universitaetsstrasse, Regensburg, Germany
    BMC Complement Altern Med 12:235. 2012
  10. doi request reprint Tinnitus: causes and clinical management
    Berthold Langguth
    Department of Psychiatry and Psychotherapy, University of Regensburg, Regensburg, Germany
    Lancet Neurol 12:920-30. 2013

Detail Information

Publications76

  1. pmc Transcranial magnetic stimulation for the treatment of tinnitus: effects on cortical excitability
    Berthold Langguth
    Department of Psychiatry, Psychosomatics and Psychotherapy, University of Regensburg, Regensburg, Germany
    BMC Neurosci 8:45. 2007
    ..Clinical improvement was assessed with a standardized tinnitus-questionnaire...
  2. pmc The revolving door phenomenon revisited: time to readmission in 17'415 patients with 37'697 hospitalisations at a German psychiatric hospital
    Ulrich Frick
    Department of Psychiatry and Psychotherapy, University of Regensburg, Regensburg, Germany Döpfer University of Applied Sciences, Department of Psychology, Cologne, Germany Research Institute on Public Health and Addiction, University of Zurich, Zurich, Switzerland
    PLoS ONE 8:e75612. 2013
    ....
  3. pmc Neuroimaging and neuromodulation: complementary approaches for identifying the neuronal correlates of tinnitus
    Berthold Langguth
    Department of Psychiatry and Psychotherapy, University of Regensburg Regensburg, Germany
    Front Syst Neurosci 6:15. 2012
    ..Available data indicate the important value added by brain stimulation as a complementary approach to neuroimaging for identifying the neuronal correlates of the various clinical aspects of tinnitus...
  4. doi request reprint Tinnitus: therapeutic use of superficial brain stimulation
    Berthold Langguth
    Interdisciplinary Tinnitus Clinic, Department of Psychiatry and Psychotherapy, University of Regensburg, Regensburg, Germany Electronic address
    Handb Clin Neurol 116:441-67. 2013
    ..In spite of the promising results of the different brain stimulation approaches, further research is needed before these techniques can be recommended for routine clinical use. ..
  5. pmc Regensburg Insomnia Scale (RIS): a new short rating scale for the assessment of psychological symptoms and sleep in insomnia; study design: development and validation of a new short self-rating scale in a sample of 218 patients suffering from insomnia and
    Tatjana Crönlein
    Department of Psychiatry and Psychotherapy, University Regensburg, Universitaetsstrasse 84, Regensburg 93042, Germany
    Health Qual Life Outcomes 11:65. 2013
    ..A specific purpose of the new scale is the evaluation of the outcome of insomnia- specific cognitive behaviour therapy (CBT-I)...
  6. pmc Tinnitus assessment by means of standardized self-report questionnaires: psychometric properties of the Tinnitus Questionnaire (TQ), the Tinnitus Handicap Inventory (THI), and their short versions in an international and multi-lingual sample
    Florian Zeman
    Center for Clinical Studies, University Hospital Regensburg, Regensburg, 93042, Germany
    Health Qual Life Outcomes 10:128. 2012
    ....
  7. pmc Linking the Tinnitus Questionnaire and the subjective Clinical Global Impression: which differences are clinically important?
    Ilya Adamchic
    Institute of Neuroscience and Medicine Neuromodulation, Research Center Julich, Leo Brand Straße, 52425, Julich, Germany
    Health Qual Life Outcomes 10:79. 2012
    ..In this study we aimed to estimate the minimum change of the TQ score that could be considered clinically relevant...
  8. pmc Sexually dimorphic effects of oxytocin receptor gene (OXTR ) variants on Harm Avoidance
    Trayana Stankova
    Department of Psychiatry and Psychotherapy, University of Regensburg, Universitaetsstrasse 84, 93053 Regensburg, Germany
    Biol Sex Differ 3:17. 2012
    ..abstract:..
  9. pmc Mindfulness-and body-psychotherapy-based group treatment of chronic tinnitus: a randomized controlled pilot study
    Peter M Kreuzer
    Department of Psychiatry and Psychotherapy, University of Regensburg, Universitaetsstrasse, Regensburg, Germany
    BMC Complement Altern Med 12:235. 2012
    ..Here we conducted a randomized, controlled clinical study to investigate the efficacy of a specific mindfulness- and body-psychotherapy based program in patients suffering from chronic tinnitus...
  10. doi request reprint Tinnitus: causes and clinical management
    Berthold Langguth
    Department of Psychiatry and Psychotherapy, University of Regensburg, Regensburg, Germany
    Lancet Neurol 12:920-30. 2013
    ..New pathophysiological insights have prompted the development of innovative brain-based treatment approaches to directly target the neuronal correlates of tinnitus...
  11. doi request reprint Current pharmacological treatments for tinnitus
    Berthold Langguth
    Department of Psychiatry and Psychotherapy, University of Regensburg, Regensburg, Germany
    Expert Opin Pharmacother 13:2495-509. 2012
    ..Tinnitus, the phantom perception of sound, is a highly prevalent disorder and treatment is elusive...
  12. pmc Deep resequencing of the voltage-gated potassium channel subunit KCNE3 gene in chronic tinnitus
    Philipp G Sand
    Department of Otorhinolaryngology, University of Regensburg, Franz Josef Strauss Allee 11, Regensburg, Germany
    Behav Brain Funct 7:39. 2011
    ..More extensive investigations are invited, including tests for possible effects of variation in this ion channel protein on the response to treatment...
  13. pmc Design of a placebo-controlled, randomized study of the efficacy of repetitive transcranial magnetic stimulation for the treatment of chronic tinnitus
    Michael Landgrebe
    Department of Psychiatry, Psychosomatics, and Psychotherapy, University of Regensburg, Germany
    BMC Psychiatry 8:23. 2008
    ..However available studies have been mono-centric and are characterized by small sample sizes. Therefore, this multi-center trial will test the efficacy of rTMS treatment in a large sample of chronic tinnitus patients...
  14. pmc Abnormal resting-state cortical coupling in chronic tinnitus
    Winfried Schlee
    Department of Psychology, University of Konstanz, Konstanz, Germany
    BMC Neurosci 10:11. 2009
    ..We hypothesized that this difference is expressed by differential activation of distributed cortical networks...
  15. pmc The Tinnitus Research Initiative (TRI) database: a new approach for delineation of tinnitus subtypes and generation of predictors for treatment outcome
    Michael Landgrebe
    Department of Psychiatry, University of Regensburg, Universitaetsstrasse 84, 93053 Regensburg, Germany
    BMC Med Inform Decis Mak 10:42. 2010
    ....
  16. pmc Treatment options for subjective tinnitus: self reports from a sample of general practitioners and ENT physicians within Europe and the USA
    Deborah A Hall
    NIHR National Biomedical Research Unit in Hearing, Nottingham, UK
    BMC Health Serv Res 11:302. 2011
    ....
  17. doi request reprint Stable motor cortex excitability in red and green lighting conditions
    Berthold Langguth
    Department of Psychiatry, University of Regensburg, Universitaetsstrasse 84, 93053 Regensburg, Germany
    Neurosci Lett 460:32-5. 2009
    ..Our results suggest that motor cortex excitability as assessed by TMS is not sensitive to the modulatory effects of context-independent red and green light...
  18. ncbi request reprint Tinnitus severity, depression, and the big five personality traits
    B Langguth
    Department of Psychiatry, University of Regensburg, Regensburg, Germany
    Prog Brain Res 166:221-5. 2007
    ..001) and TQ scores (p=.028), but not with THI ratings (n.s.). In addition to confirming the established roles of trait anxiety and depression, low 'Agreeableness' was thus identified as a novel predictor of tinnitus severity on the THI...
  19. doi request reprint Allelic variation in the serotonin transporter promoter modulates cortical excitability
    Berthold Langguth
    Department of Psychiatry, University of Regensburg, Universitaetsstrasse 84, Regensburg D 93053, Germany
    Biol Psychiatry 66:283-6. 2009
    ..Transcranial magnetic stimulation (TMS) is a noninvasive procedure that may be used to study individual differences in motor cortex excitability. Such differences are assumed to reflect serotonergic and other inputs to the motor cortex...
  20. ncbi request reprint Consensus for tinnitus patient assessment and treatment outcome measurement: Tinnitus Research Initiative meeting, Regensburg, July 2006
    B Langguth
    Department of Psychiatry, University of Regensburg, Regensburg, Germany
    Prog Brain Res 166:525-36. 2007
    ..It is hoped that this will contribute towards better cooperation between research centres in finding and evaluating treatments for tinnitus by allowing better comparability between studies...
  21. ncbi request reprint Tinnitus and Coxsackie B infections: a case series
    Berthold Langguth
    Department of Psychiatry, Psychosomatics and Psychotherapy, University of Regensburg, Germany
    Neuro Endocrinol Lett 28:554-5. 2007
    ..This observation suggests that Coxsackie B Virus infections might be involved in the development of some cases of tinnitus and indicate that further systematic investigations are warranted...
  22. ncbi request reprint Pre-treatment anterior cingulate activity as a predictor of antidepressant response to repetitive transcranial magnetic stimulation (rTMS)
    Berthold Langguth
    Department of Psychiatry, Psychosomatics and Psychotherapy, University of Regensburg, Germany
    Neuro Endocrinol Lett 28:633-8. 2007
    ..Therefore we investigated whether either alterations of regional cerebral blood flow (rCBF) or clinical characteristics may predict antidepressant response to rTMS...
  23. ncbi request reprint Modulation of human motor cortex excitability by quetiapine
    Berthold Langguth
    Department of Psychiatry, University of Regensburg, Universitaetsstrasse 84, D 93053 Regensburg, Germany
    Psychopharmacology (Berl) 196:623-9. 2008
    ..Quetiapine is increasingly used for the treatment of patients with psychosis and bipolar disorder. However, the neurobiological mechanisms, which may account for the favourable risk/benefit profile of this drug, are not entirely understood...
  24. ncbi request reprint High-frequency priming stimulation does not enhance the effect of low-frequency rTMS in the treatment of tinnitus
    Berthold Langguth
    Department of Psychiatry, Psychotherapy and Psychosomatics, University of Regensburg, Universitaetsstrasse 84, 93053 Regensburg, Germany
    Exp Brain Res 184:587-91. 2008
    ..Our data does not support an enhancing effect of higher frequency priming on low-frequency rTMS in the treatment of tinnitus...
  25. doi request reprint Modulating cerebello-thalamocortical pathways by neuronavigated cerebellar repetitive transcranial stimulation (rTMS)
    B Langguth
    Department of Psychiatry, Psychosomatics and Psychotherapy, University of Regensburg, Universitaetsstrasse, 84, 93053 Regensburg, Germany
    Neurophysiol Clin 38:289-95. 2008
    ..This study explores the effects of cerebellar repetitive transcranial magnetic stimulation (rTMS) on cerebello-thalamocortical pathways...
  26. pmc Emerging pharmacotherapy of tinnitus
    Berthold Langguth
    University of Regensburg, Interdisciplinary Tinnitus Clinic, Department of Psychiatry and Psychotherapy, Universitaetsstrabetae 84, 93053 Regensburg, Germany
    Expert Opin Emerg Drugs 14:687-702. 2009
    ....
  27. doi request reprint rTMS for the treatment of tinnitus: the role of neuronavigation for coil positioning
    B Langguth
    Department of Psychiatry and Psychotherapy, University of Regensburg, Universitaetsstrasse 84, 93053 Regensburg, Germany
    Neurophysiol Clin 40:45-58. 2010
    ....
  28. ncbi request reprint [Low frequency repetitive transcranial magnetic stimulation (rTMS) for the treatment of chronic tinnitus--are there long-term effects?]
    Berthold Langguth
    Klinik für Psychiatrie und Psychotherapie der Universität am Bezirksklinikum Regensburg
    Psychiatr Prax 31:S52-4. 2004
    ..Low frequency repetitive transcranial magnetic stimulation (rTMS) has been proposed as an efficient method in treating brain hyperexcitability disorders...
  29. ncbi request reprint Altered motor cortex excitability in tinnitus patients: a hint at crossmodal plasticity
    Berthold Langguth
    Department of Psychiatry and Psychotherapy, University of Regensburg, Universitaetsstrasse 84, 93053 Regensburg, Germany
    Neurosci Lett 380:326-9. 2005
    ..Our results give further support to crossmodal interactions involving neuroplastic changes in some forms of tinnitus and may help to better understand mechanisms of maladaptive cortical reorganisation involved in phantom perceptions...
  30. ncbi request reprint Repetitive transcranial magnetic stimulation in a patient suffering from depression and rheumatoid arthritis: evidence for immunomodulatory effects
    Berthold Langguth
    Department of Psychiatry, Psychosomatics and Psychotherapy, University of Regensburg, Germany
    Neuro Endocrinol Lett 26:314-6. 2005
    ..Improvement of depressive symptoms during 20 Hz rTMS of the left dorsolateral prefrontal cortex was repeatedly associated with a systemic inflammatory reaction, suggesting that rTMS induced an immunomodulatory effect...
  31. ncbi request reprint Emerging pharmacotherapy of tinnitus
    Berthold Langguth
    University of Regensburg, Interdisciplinary Tinnitus Clinic, Department of Psychiatry and Psychotherapy, Universitaetsstraße 84, 93053 Regensburg, Germany 49 941 941 2099 49 941 941 2025
    Expert Opin Emerg Drugs 16:603-6. 2011
    ..A glimpse of hope is appearing in the horizon as an increasing number of pharmaceutical industries now have compounds targeting tinnitus in their pipeline...
  32. ncbi request reprint Transcranial magnetic stimulation for the treatment of tinnitus: a new coil positioning method and first results
    Berthold Langguth
    Department of Psychiatry, Psychotherapy and Psychosomatics, University of Regensburg, Universitatsstrasse 84, 93053 Regensburg, Germany
    Brain Topogr 18:241-7. 2006
    ..001). The newly developed coil positioning strategy may have the potential to offer a more easy-to-use stimulation approach for treating chronic tinnitus as compared with highly sophisticated, imaging guided treatment methods...
  33. doi request reprint A review of tinnitus symptoms beyond 'ringing in the ears': a call to action
    Berthold Langguth
    Department of Psychiatry, University of Regensburg, Regensburg, Germany
    Curr Med Res Opin 27:1635-43. 2011
    ..Tinnitus, often referred to as 'ringing in the ears', is highly prevalent. However, patients may also present with a number of other symptoms...
  34. doi request reprint Tinnitus and depression
    Berthold Langguth
    Department of Psychiatry and Psychotherapy, University of Regensburg, Regensburg, Germany
    World J Biol Psychiatry 12:489-500. 2011
    ..Depressive symptoms are common in individuals with tinnitus and may substantially aggravate their distress. The mechanisms, however, by which depression and tinnitus mutually interact are still not fully understood...
  35. ncbi request reprint Modulation of human motor cortex excitability by the cholinesterase inhibitor rivastigmine
    Berthold Langguth
    Department of Psychiatry and Psychotherapy, University of Regensburg, Germany
    Neurosci Lett 415:40-4. 2007
    ..The differential effect between acute and chronic administration of rivastigmine may reflect dynamic properties of different receptor subtypes...
  36. doi request reprint Tinnitus: the complexity of standardization
    Berthold Langguth
    Department of Psychiatry and Psychotherapy, University of Regensburg, Regensburg, Germany
    Eval Health Prof 34:429-33. 2011
    ..They should also contain treatment recommendations that have shown clinically highly relevant effects in case series of specific tinnitus subgroups...
  37. doi request reprint Controversy: Does repetitive transcranial magnetic stimulation/ transcranial direct current stimulation show efficacy in treating tinnitus patients?
    Berthold Langguth
    Department of Psychiatry, University of Regensburg, Germany
    Brain Stimul 1:192-205. 2008
    ..Therefore, targeted modulation of auditory cortex has been proposed as a new therapeutic approach for chronic tinnitus...
  38. ncbi request reprint TMS for treatment of chronic tinnitus: neurobiological effects
    P Eichhammer
    Department of Psychiatry, University of Regensburg, Universitaetsstrasse 84, 93053, Regensburg, Germany
    Prog Brain Res 166:369-75. 2007
    ..All other signs of cortical excitability that we studied remained unchanged. These findings suggest, that low frequency rTMS may evoke long-term depression (LTD)-like effects resulting in enhancement of subcortical inhibition...
  39. ncbi request reprint Altered cortical excitability in subjectively electrosensitive patients: results of a pilot study
    Michael Landgrebe
    Department of Psychiatry, Psychosomatics, and Psychotherapy, University of Regensburg, Regensburg, Germany
    J Psychosom Res 62:283-8. 2007
    ....
  40. ncbi request reprint Left temporal low-frequency rTMS for the treatment of tinnitus: clinical predictors of treatment outcome--a retrospective study
    G Frank
    Department of Psychiatry and Psychotherapy, University of Regensburg, Regensburg, Germany
    Eur J Neurol 17:951-6. 2010
    ..However, treatment results are characterized by high interindividual variability. Therefore, the identification of predictors for treatment response is of high clinical relevance...
  41. doi request reprint Cognitive and neurobiological alterations in electromagnetic hypersensitive patients: results of a case-control study
    M Landgrebe
    Department of Psychiatry, Psychosomatics, and Psychotherapy, University of Regensburg, Regensburg, Germany
    Psychol Med 38:1781-91. 2008
    ....
  42. ncbi request reprint Functional imaging of chronic tinnitus: the use of positron emission tomography
    P Eichhammer
    Department of Psychiatry, University of Regensburg, Universitaetsstrasse 84, 93053, Regensburg, Germany
    Prog Brain Res 166:83-8. 2007
    ..PET studies that map distinct neurochemical pathways and receptors by the use of specific ligands may in the future provide new possibilities for pharmacologically based treatment of some forms of tinnitus...
  43. ncbi request reprint Long-term effects of repetitive transcranial magnetic stimulation (rTMS) in patients with chronic tinnitus
    Tobias Kleinjung
    Department of Otorhinolaryngology, University of Regensburg, Germany
    Otolaryngol Head Neck Surg 132:566-9. 2005
    ..Recent studies demonstrated focal brain activation in the auditory cortex of patients with chronic tinnitus. Low-frequency repetitive transcranial magnetic stimulation (rTMS) is able to reduce cortical hyperexcitability...
  44. ncbi request reprint Efficacy of different protocols of transcranial magnetic stimulation for the treatment of tinnitus: Pooled analysis of two randomized controlled studies
    B Langguth
    Department of Psychiatry and Psychotherapy, University of Regensburg, Regensburg, Germany
    World J Biol Psychiatry 15:276-85. 2014
    ..Targeted modulation of these areas by repetitive transcranial magnetic stimulation (rTMS) has been proposed as a new therapeutic approach for chronic tinnitus...
  45. ncbi request reprint High-frequency repetitive transcranial magnetic stimulation in schizophrenia: a combined treatment and neuroimaging study
    G Hajak
    Department of Psychiatry and Psychotherapy, University of Regensburg, Regensburg, Germany
    Psychol Med 34:1157-63. 2004
    ..In this context, disentangling of negative and depressive symptoms is of the utmost importance when understanding specific rTMS effects on schizophrenic symptoms...
  46. ncbi request reprint Cortical excitability in neuroleptic-naive first-episode schizophrenic patients
    Peter Eichhammer
    Department of Psychiatry and Psychotherapy, University of Regensburg, Universitaetsstrasse 84, 93053 Regensburg, Germany
    Schizophr Res 67:253-9. 2004
    ..In agreement with recent results of functional imaging, our neurophysiological findings suggest that drug-induced and naturally occurring psychosis may share a common pathway, which may base on dysfunctional glutamatergic mechanisms...
  47. ncbi request reprint Transcranial magnetic stimulation (TMS) for treatment of chronic tinnitus: clinical effects
    T Kleinjung
    Department of Otorhinolaryngology, University of Regensburg, Regensburg, Germany
    Prog Brain Res 166:359-67. 2007
    ..This chapter will review clinical studies using rTMS for the treatment of tinnitus...
  48. ncbi request reprint Sleep deprivation in depression stabilizing antidepressant effects by repetitive transcranial magnetic stimulation
    P Eichhammer
    Department of Psychiatry and Psychotherapy, University of Regensburg, Germany
    Life Sci 70:1741-9. 2002
    ..Active stimulation prolonged significantly (p < 0.001) the antidepressant effect of PSD up to 4 days. This finding indicates that rTMS is an efficacious method to prevent relapse after PSD...
  49. ncbi request reprint Genetics of chronic tinnitus
    P G Sand
    Department of Psychiatry, University of Regensburg, Regensburg, Germany
    Prog Brain Res 166:159-68. 2007
    ..The present article incorporates recent advancements in the field, including the epidemiology of tinnitus in subjects with neuropsychiatric illness, and highlights pilot studies of candidate genes...
  50. ncbi request reprint Neuronavigated repetitive transcranial magnetic stimulation in patients with tinnitus: a short case series
    Peter Eichhammer
    Department of Psychiatry and Psychotherapy, University of Regensburg, Universitaetstrasse 84, Regensburg 93053, Germany
    Biol Psychiatry 54:862-5. 2003
    ..Low-frequency repetitive transcranial magnetic stimulation (rTMS) has been proposed as an efficient method in treating brain hyperexcitability disorders by reducing cortical excitability...
  51. ncbi request reprint [GABA-B-associated neuropsychiatric disorders]
    Peter Eichhammer
    Klinik für Psychiatrie und Psychotherapie der Universität Regensburg
    Psychiatr Prax 31:S44-6. 2004
    ..Transcranial magnetic stimulation (TMS) provides an intriguing in vivo method to investigate GABA-B associated aspects of cortical inhibition, thus allowing to detect disease-related cortical inhibitory processes...
  52. ncbi request reprint [The neuronal level of motor activity: determination of motor cortex excitability by TMS]
    Peter Eichhammer
    Klinik und Poliklinik für Psychiatrie und Psychotherapie der Universität Regensburg
    Psychiatr Prax 32:S43-6. 2005
    ..In combination with genetic aspects, TMS is able to bridge the gap between molecular research and clinical approach...
  53. ncbi request reprint Tinnitus and insomnia
    Tatjana Crönlein
    Sleep Disorders and Research Center, Department of Psychiatry and Psychotherapy, University of Regensburg, Universitätsstr 84, 93053, Regensburg, Germany
    Prog Brain Res 166:227-33. 2007
    ..Similarities between the results from these two groups suggest that sleep specific psychotherapeutic methods, which are established for treating insomnia, should be further developed for the use in patients with insomnia and tinnitus...
  54. doi request reprint Structural brain changes in tinnitus: grey matter decrease in auditory and non-auditory brain areas
    Michael Landgrebe
    Department of Psychiatry, Psychosomatics, and Psychotherapy, University of Regensburg, Universitaetsstrasse 84, 93053 Regensburg, Germany
    Neuroimage 46:213-8. 2009
    ..3.) Even groups with similar clinical characteristics might differ in the underlying neurobiological changes...
  55. ncbi request reprint Effects of colour exposure on auditory and somatosensory perception--hints for cross-modal plasticity
    Michael Landgrebe
    Department of Psychiatry, Psychosomatics and Psychotherapy, University of Regensburg, Regensburg, Germany
    Neuro Endocrinol Lett 29:518-21. 2008
    ..To get further insight into these complex synesthetic phenomena, the effect of colour stimulation on auditory and somatosensory perception was systematically investigated...
  56. pmc Association of tinnitus and electromagnetic hypersensitivity: hints for a shared pathophysiology?
    Michael Landgrebe
    Department of Psychiatry, Psychosomatics, and Psychotherapy, University of Regensburg, Regensburg, Germany
    PLoS ONE 4:e5026. 2009
    ..The aim of the study was to elucidate the relationship between EMF-exposure, electromagnetic hypersensitivity and tinnitus using a case-control design...
  57. ncbi request reprint Neuronavigated rTMS in a patient with chronic tinnitus. Effects of 4 weeks treatment
    Berthold Langguth
    Department of Psychiatry, University of Regensburg, Germany
    Neuroreport 14:977-80. 2003
    ..These findings suggest that neuronavigated rTMS of increased PAC activity might offer a new option for treating auditory phantom perceptions like chronic tinnitus...
  58. ncbi request reprint Cerebellar and thalamic metabolic changes visualized by [18]-FDG-PET in olanzapine-induced acute akathisia
    Michael Landgrebe
    Department of Psychiatry, Psychosomatics and Psychotherapy, University of Regensburg, Germany
    Neuro Endocrinol Lett 27:737-9. 2006
    ..Akathisia is a clinical important symptom, frequently induced by neuroleptic treatment. Despite its clinical importance, less is known about its pathophysiology...
  59. doi request reprint Combined temporal and prefrontal transcranial magnetic stimulation for tinnitus treatment: a pilot study
    Tobias Kleinjung
    Department of Otorhinolaryngology, University of Regensburg, Regensburg, Germany
    Otolaryngol Head Neck Surg 138:497-501. 2008
    ..Therefore, we have developed a new rTMS treatment strategy for tinnitus patients that consists of a combination of high-frequency prefrontal and low-frequency temporal rTMS...
  60. ncbi request reprint Neuronal correlates of symptom formation in functional somatic syndromes: a fMRI study
    Michael Landgrebe
    Department of Psychiatry, Psychosomatics, and Psychotherapy, University of Regensburg, Germany
    Neuroimage 41:1336-44. 2008
    ....
  61. pmc Resequencing of the auxiliary GABA(B) receptor subunit gene KCTD12 in chronic tinnitus
    P G Sand
    Department of Psychiatry, University of Regensburg Regensburg, Germany
    Front Syst Neurosci 6:41. 2012
    ..Issues that are yet to be addressed include the effects of neighboring variants, e.g., in the KCTD12 gene regulatory region, plus interactions with variants of GABA(B1) and GABA(B2)...
  62. doi request reprint Repetitive transcranial magnetic stimulation for the treatment of negative symptoms in residual schizophrenia: rationale and design of a sham-controlled, randomized multicenter study
    Joachim Cordes
    Department of Psychiatry and Psychotherapy, Heinrich Heine University of Dusseldorf, Bergische Landstr 2, 40629 Düsseldorf, Germany
    Eur Arch Psychiatry Clin Neurosci 259:S189-97. 2009
    ..Main limitations of the trial are the potential influence of antipsychotic dosage changes and the difficulty to ensure adequate blinding...
  63. ncbi request reprint Allelic variation in the serotonin transporter promoter affects neuromodulatory effects of a selective serotonin transporter reuptake inhibitor (SSRI)
    Peter Eichhammer
    Department of Psychiatry and Psychotherapy, University of Regensburg, Universitaetsstrasse 84, 93053, Regensburg, Germany
    Psychopharmacology (Berl) 166:294-7. 2003
    ..Paired pulse transcranial magnetic stimulation is a feasible tool in detecting changes of motor cortex excitability induced by SSRIs...
  64. doi request reprint Levodopa does not enhance the effect of low-frequency repetitive transcranial magnetic stimulation in tinnitus treatment
    Tobias Kleinjung
    Department of Otorhinolaryngology, University of Regensburg, Regensburg, Germany
    Otolaryngol Head Neck Surg 140:92-5. 2009
    ..Here we investigated whether administration of the dopamine precursor levodopa before low-frequency rTMS enhances its efficacy in tinnitus treatment...
  65. ncbi request reprint Transcranial magnetic stimulation: a new diagnostic and therapeutic tool for tinnitus patients
    Tobias Kleinjung
    Department of Otorhinolaryngology, University of Regensburg, Regensburg, Germany
    Int Tinnitus J 14:112-8. 2008
    ..g., hearing loss, tinnitus duration, age) and stimulation-related (e.g., stimulation site, stimulation protocols) factors seem to influence treatment outcome; however, their exact impact still remains to be clarified...
  66. ncbi request reprint Effects of spinal cord stimulation on cortical excitability in patients with chronic neuropathic pain: a pilot study
    Jürgen R Schlaier
    Department of Neurosurgery, University of Regensburg, 93053 Regensburg, Franz Josef Strauss Allee 11, Germany
    Eur J Pain 11:863-8. 2007
    ..Current information suggests that the effects of SCS are mediated by a complex set of interactions at several levels of the nervous system including spinal and supraspinal mechanisms...
  67. ncbi request reprint Which tinnitus patients benefit from transcranial magnetic stimulation?
    Tobias Kleinjung
    Department of Otorhinolaryngology, University of Regensburg, Germany
    Otolaryngol Head Neck Surg 137:589-95. 2007
    ..Low-frequency repetitive transcranial magnetic stimulation (rTMS) of the temporal cortex has been proposed as a treatment for chronic tinnitus. This study determined the factors that predict a beneficial outcome with rTMS treatment...
  68. ncbi request reprint Strategies for enhancement of transcranial magnetic stimulation effects in tinnitus patients
    Tobias Kleinjung
    Department of Otorhinolaryngology and Interdisciplinary Tinnitus Center, University of Regensburg, Regensburg, Germany
    Int Tinnitus J 15:154-60. 2009
    ..Successful enhancement of treatment effects will depend on a more detailed understanding of the neuronal correlates of the different forms of tinnitus and the mechanisms by which rTMS exerts its effects...
  69. ncbi request reprint Repetitive transcranial magnetic stimulation for maintenance treatment of depression: a case report
    Berthold Langguth
    J Clin Psychiatry 67:835-6. 2006
  70. ncbi request reprint Neuronavigated transcranial magnetic stimulation and auditory hallucinations in a schizophrenic patient: monitoring of neurobiological effects
    Berthold Langguth
    Schizophr Res 84:185-6. 2006
  71. doi request reprint Tinnitus treatment with memantine
    Ricardo Rodrigues Figueiredo
    OTOSUL Otorrinolaringologia Sul Fluminense
    Otolaryngol Head Neck Surg 138:492-6. 2008
    ..To evaluate efficacy and safety of memantine in the treatment of tinnitus...
  72. ncbi request reprint [No evidence for gender-specific sharing of COMT alleles in schizophrenia]
    Philipp Sand
    Klinik und Poliklinik für Psychiatrie und Psychotherapie der Universität am Bezirksklinikum Regensburg
    Psychiatr Prax 31:S58-60. 2004
    ..4). While studies involving same-sex siblings are lacking, gender-specific sharing of alleles does not appear to be a consistent feature of the COMT variant investigated...
  73. doi request reprint Tinnitus aurium in persons with normal hearing: 55 years later
    Luca Del Bo
    Fondazione Ascolta e Vivi, Milan, Italy
    Otolaryngol Head Neck Surg 139:391-4. 2008
    ..The aim of this study was to investigate the effect of silence on the appearance of auditory phantom perceptions in normal-hearing adults, with specific emphasis on the influence of suggestion...
  74. ncbi request reprint COMT Association Data in Schizophrenia: New Caveats
    Philipp G Sand
    Biol Psychiatry 60:663-4; author reply 664-5. 2006
  75. ncbi request reprint Transcranial magnetic stimulation: potential treatment for tinnitus?
    Saxby Pridmore
    Discipline of Psychiatry, University of Tasmania, Hobart, Tasmania, Australia
    Psychiatry Clin Neurosci 60:133-8. 2006
    ..There is a good theoretical basis and early research evidence suggesting that TMS may have treatment potential in tinnitus. Further, larger studies are necessary...
  76. ncbi request reprint A putative DRD3 schizophrenia risk haplotype deconstructed
    Philipp G Sand
    Biol Psychiatry 63:e21; author reply e23-5. 2008