Affiliation: University of Munich
- Dynamic genome architecture in the nuclear space: regulation of gene expression in three dimensionsChristian Lanctôt
Department Biologie II, Ludwig Maximilians Universitat, Grosshadernerstr 2, Planegg Martinsried, Germany
Nat Rev Genet 8:104-15. 2007..Understanding how the dynamic nature of the positioning of genetic material in the nuclear space and the higher-order architecture of the nucleus are integrated is therefore essential to our overall understanding of gene regulation...
- Positioning of the mouse Hox gene clusters in the nuclei of developing embryos and differentiating embryoid bodiesChristian Lanctôt
Department Biology II, Ludwig Maximilians University Munich, Grosshadernerstr 2, Planegg Martinsried, 82152, Germany
Exp Cell Res 313:1449-59. 2007....
- Multicolor 3D fluorescence in situ hybridization for imaging interphase chromosomesMarion Cremer
Department of Biology II, Ludwig Maximilians University Biozentrum, Planegg Martinsried, Germany
Methods Mol Biol 463:205-39. 2008....
- Nuclear architecture of rod photoreceptor cells adapts to vision in mammalian evolutionIrina Solovei
Division of Anthropology and Human Genetics, Biocenter, Ludwig Maximilians University Munich, Grosshadernerstrasse 2, 82152 Planegg Martinsried, Germany
Cell 137:356-68. 2009..Comparison of the two patterns suggests that the conventional architecture prevails in eukaryotic nuclei because it results in more flexible chromosome arrangements, facilitating positional regulation of nuclear functions...
- FISH on Histological SectionsIrina Solovei
Ludwig Maximilians University Munich, Department of Biology II, AG Thomas Cremer Chair of Anthropology and Human Genetics, 82152 Martinsried Planegg, Germany
CSH Protoc 2007:pdb.prot4729. 2007..Because the goal of the technique is to obtain data on the native 3D structure of the genome, close attention is paid to the preservation of nuclear morphology...