Angelika Lampert

Summary

Affiliation: University of Erlangen-Nuremberg
Country: Germany

Publications

  1. pmc Bisphenol A binds to the local anesthetic receptor site to block the human cardiac sodium channel
    Andrias O O'Reilly
    Institute of Physiology and Pathophysiology, Friedrich Alexander Universitat Erlangen Nurnberg, Bavaria, Germany
    PLoS ONE 7:e41667. 2012
  2. ncbi request reprint Sodium channelopathies and pain
    Angelika Lampert
    Department of Physiology and Pathophysiology, Friedrich Alexander University Erlangen Nuremberg, Universitatsstrasse 17, 91054, Erlangen, Germany
    Pflugers Arch 460:249-63. 2010
  3. doi request reprint Inherited pain: sodium channel Nav1.7 A1632T mutation causes erythromelalgia due to a shift of fast inactivation
    Mirjam Eberhardt
    From the Institute of Physiology and Pathophysiology, Friedrich Alexander Universitat Erlangen Nurnberg, Universitatsstrasse 17, 91054 Erlangen, Germany
    J Biol Chem 289:1971-80. 2014
  4. pmc Sea-anemone toxin ATX-II elicits A-fiber-dependent pain and enhances resurgent and persistent sodium currents in large sensory neurons
    Alexandra B Klinger
    Institute of Physiology and Pathophysiology, Friedrich Alexander Universitat Erlangen Nurnberg, Universitätsstraße 17, 91054 Erlangen, Germany
    Mol Pain 8:69. 2012
  5. doi request reprint The distinct effects of lipid emulsions used for "lipid resuscitation" on gating and bupivacaine-induced inhibition of the cardiac sodium channel Nav1.5
    Felix Nadrowitz
    From the Departments of Anesthesiology and Intensive Care Medicine and Neurology, Hannover Medical School, Hannover, Germany and Institute for Physiology and Pathophysiology, Friedrich Alexander Universitat Erlangen Nurnberg, Germany
    Anesth Analg 117:1101-8. 2013
  6. doi request reprint Sensory renal innervation: a kidney-specific firing activity due to a unique expression pattern of voltage-gated sodium channels?
    Wolfgang Freisinger
    Dept of Medicine 4, Univ of Erlangen Nürnberg, Loschgestraβe 8, 91054 Erlangen, Germany
    Am J Physiol Renal Physiol 304:F491-7. 2013

Collaborators

Detail Information

Publications6

  1. pmc Bisphenol A binds to the local anesthetic receptor site to block the human cardiac sodium channel
    Andrias O O'Reilly
    Institute of Physiology and Pathophysiology, Friedrich Alexander Universitat Erlangen Nurnberg, Bavaria, Germany
    PLoS ONE 7:e41667. 2012
    ..Therefore BPA block of the human heart sodium channel involves the local anesthetic receptor and both BPA and mexiletine may enter the closed-state pore via membrane-located side fenestrations...
  2. ncbi request reprint Sodium channelopathies and pain
    Angelika Lampert
    Department of Physiology and Pathophysiology, Friedrich Alexander University Erlangen Nuremberg, Universitatsstrasse 17, 91054, Erlangen, Germany
    Pflugers Arch 460:249-63. 2010
    ..We also recapitulate the role of Nav1.8 for peripheral pain processing and of additional sodium channelopathies which have been linked to disorders with pain as a significant component...
  3. doi request reprint Inherited pain: sodium channel Nav1.7 A1632T mutation causes erythromelalgia due to a shift of fast inactivation
    Mirjam Eberhardt
    From the Institute of Physiology and Pathophysiology, Friedrich Alexander Universitat Erlangen Nurnberg, Universitatsstrasse 17, 91054 Erlangen, Germany
    J Biol Chem 289:1971-80. 2014
    ..7 mutation, A1632T. Therefore, persistent and resurgent currents are likely to determine whether a mutation in Nav1.7 leads to IEM or PEPD. ..
  4. pmc Sea-anemone toxin ATX-II elicits A-fiber-dependent pain and enhances resurgent and persistent sodium currents in large sensory neurons
    Alexandra B Klinger
    Institute of Physiology and Pathophysiology, Friedrich Alexander Universitat Erlangen Nurnberg, Universitätsstraße 17, 91054 Erlangen, Germany
    Mol Pain 8:69. 2012
    ..Here, we investigated if ATX-II induces resurgent currents in sensory neurons of the dorsal root ganglion (DRGs) and how this may translate into human sensations...
  5. doi request reprint The distinct effects of lipid emulsions used for "lipid resuscitation" on gating and bupivacaine-induced inhibition of the cardiac sodium channel Nav1.5
    Felix Nadrowitz
    From the Departments of Anesthesiology and Intensive Care Medicine and Neurology, Hannover Medical School, Hannover, Germany and Institute for Physiology and Pathophysiology, Friedrich Alexander Universitat Erlangen Nurnberg, Germany
    Anesth Analg 117:1101-8. 2013
    ..5. In this study, we sought to determine whether lipid emulsions functionally interact with Nav1.5 or counteract inhibition by bupivacaine...
  6. doi request reprint Sensory renal innervation: a kidney-specific firing activity due to a unique expression pattern of voltage-gated sodium channels?
    Wolfgang Freisinger
    Dept of Medicine 4, Univ of Erlangen Nürnberg, Loschgestraβe 8, 91054 Erlangen, Germany
    Am J Physiol Renal Physiol 304:F491-7. 2013
    ..Our findings support that this is due to an increased expression and activation of TTX-resistant Navs...