Research Topics
| Christian la FougereSummaryAffiliation: University of Munich Country: Germany Publications
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Detail Information
Publications
Prediction of oligodendroglial histology and LOH 1p/19q using dynamic [(18)F]FET-PET imaging in intracranial WHO grade II and III gliomasNathalie L Jansen
Department of Nuclear Medicine, University of Munich, Munich, Germany
Neuro Oncol 14:1473-80. 2012..Histological examination is still required for an accurate diagnosis...
PET and SPECT in epilepsy: a critical reviewC la Fougere
Department of Nuclear Medicine, Ludwig Maximilian University of Munich, Marchioninistrasse 15, D 81377 Munich, Germany
Epilepsy Behav 15:50-5. 2009..Currently some of these radioligands are also used to investigate new treatment approaches...
Where in-vivo imaging meets cytoarchitectonics: the relationship between cortical thickness and neuronal density measured with high-resolution [18F]flumazenil-PETChristian la Fougere
McConnell Brain Imaging Centre, Montreal Neurological Institute, McGill University, Montreal, Canada
Neuroimage 56:951-60. 2011....
Restaging of patients with lymphoma. Comparison of low dose CT (20 mAs) with contrast enhanced diagnostic CT in combined [18F]-FDG PET/CTC la Fougere
Department of Nuclear Medicine, Ludwig Maximilians University, Munich, Germany
Nuklearmedizin 47:37-42. 2008..Assessment of the clinical benefit of i.v. contrast enhanced diagnostic CT (CE-CT) compared to low dose CT with 20 mAs (LD-CT) without contrast medium in combined [(18)F]-FDG PET/CT examinations in restaging of patients with lymphoma...
The value of the dopamine D2/3 receptor ligand 18F-desmethoxyfallypride for the differentiation of idiopathic and nonidiopathic parkinsonian syndromesChristian la Fougere
Department of Nuclear Medicine, University of Munich, Munich, Germany
J Nucl Med 51:581-7. 2010..On the basis of the superior sensitivity of PET, we hypothesized that (18)F-DMFP should have properties for the differential diagnosis of these syndromes superior to what has been reported for the more conventional SPECT procedures...
Uptake and binding of the serotonin 5-HT1A antagonist [18F]-MPPF in brain of rats: effects of the novel P-glycoprotein inhibitor tariquidarChristian la Fougere
Department of Nuclear Medicine, Ludwig Maximilians University of Munich, Germany
Neuroimage 49:1406-15. 2010..TQD (15 mg/kg) evoked a 45% global increase in [(18)F]-FDG uptake, suggesting perturbation of brain energy metabolism due to P-gp blockade...
Value of 99mTc-TRODAT-1 SPECT to predict clinical response to methylphenidate treatment in adults with attention deficit hyperactivity disorderChristian la Fougere
Department of Nuclear Medicine, Ludwig Maximilians University of Munich, Germany
Nucl Med Commun 27:733-7. 2006..In a previous study, binding of Tc-TRODAT-1 to the dopamine transporter (DAT) was found to be higher in patients with attention deficit hyperactivity disorder (ADHD) as compared to healthy controls...
Value of PET/CT versus PET and CT performed as separate investigations in patients with Hodgkin's disease and non-Hodgkin's lymphomaChristian la Fougere
Department of Nuclear Medicine, Ludwig Maximilians University of Munich, Munich, Germany
Eur J Nucl Med Mol Imaging 33:1417-25. 2006..The aim of this study was to assess the clinical benefit of combined [(18)F]FDG PET/CT in patients with malignant lymphoma as compared to separately performed PET and CT...
Hepatic yttrium-90 radioembolization of chemotherapy-refractory colorectal cancer liver metastasesTobias F Jakobs
Department of Radiology, Ludwig Maximilians University of Munich, Munich, Germany
J Vasc Interv Radiol 19:1187-95. 2008..To present data for radioembolization with yttrium-90 ((90)Y) resin microspheres in patients with colorectal cancer liver metastases in whom currently available therapies had failed...
[18F]Fallypride PET measurement of striatal and extrastriatal dopamine D 2/3 receptor availability in recently abstinent alcoholicsAxel Rominger
Department of Nuclear Medicine, Ludwig Maximilians University of Munich, Germany
Addict Biol 17:490-503. 2012..Receptor availability was unaltered by acute withdrawal, but increased in the subgroup of patients with long-term follow-up, suggesting reversibility of receptor changes...
Compensation for cranial spill-in into the cerebellum improves quantitation of striatal dopamine D₂/₃ receptors in rats with prolonged [¹⁸F]-DMFP infusionsErik Mille
Department of Nuclear Medicine, University Hospital of the Ludwig Maximilians University of Munich, Munich, Germany
Synapse 66:705-13. 2012..Based on this phenomenon, we developed an analytic method compensating for the effects of progressive cranial labeling on the estimation of specific binding in striatum...
Imaging of P-glycoprotein-mediated pharmacoresistance in the hippocampus: proof-of-concept in a chronic rat model of temporal lobe epilepsyHero Bartmann
Institute of Pharmacology, Toxicology, and Pharmacy, Ludwig Maximilians University, Munich, Germany
Epilepsia 51:1780-90. 2010..The preclinical study is intended for eventual translation to clinical research of patients with pharmacoresistant seizure disorders...
MRI-suspected low-grade glioma: is there a need to perform dynamic FET PET?Nathalie L Jansen
Department of Nuclear Medicine, Ludwig Maximilians University Munich, Marchioninistr 15, 81377 Munich, Germany
Eur J Nucl Med Mol Imaging 39:1021-9. 2012..Since differentiation between low-grade glioma (LGG) and high-grade glioma (HGG) remains challenging according to MRI criteria alone, we investigated the discriminative value of additional dynamic FET PET in patients with MRI-suspected LGG...
D2 receptor occupancy during high- and low-dose therapy with the atypical antipsychotic amisulpride: a 123I-iodobenzamide SPECT studyChristian la Fougere
Department of Nuclear Medicine, Ludwig Maximillians University of Munich, Ziemssenstrasse 1, 80336 Munich, Germany
J Nucl Med 46:1028-33. 2005..The aim of this study was to assess striatal dopamine D(2) receptor availability by means of (123)I-iodobenzamide (IBZM) SPECT in patients treated with high and low doses of this atypical antipsychotic drug...
Effects of a 6-month cognitive intervention program on brain metabolism in amnestic mild cognitive impairment and mild Alzheimer's diseaseStefan Forster
Department of Nuclear Medicine, Ludwig Maximilian University, Munich, Germany
J Alzheimers Dis 25:695-706. 2011..A six-month cognitive intervention imparted cognitive benefits in patients with aMCI, which were concurrent with an attenuated decline of glucose metabolism in cortical regions affected by neurodegenerative AD...
Quantitative assessment of cardiac allograft vasculopathy by real-time myocardial contrast echocardiography: a comparison with conventional echocardiographic analyses and [Tc99m]-sestamibi SPECTMarcus Hacker
Department of Cardiology, Medizinische Poliklinik, Innenstadt, University of Munich, Ziemssenstrasse 1, 80336 Munchen, Germany
Eur J Echocardiogr 9:494-500. 2008..To evaluate the additional benefit of visual and quantitative perfusion measurements compared with conventional real-time myocardial contrast echocardiography (MCE) in the detection of CAV...
In vivo imaging of macrophage activity in the coronary arteries using 68Ga-DOTATATE PET/CT: correlation with coronary calcium burden and risk factorsAxel Rominger
Department of Nuclear Medicine, University of Munich, Munich, Germany
J Nucl Med 51:193-7. 2010....
Real versus imagined locomotion: a [18F]-FDG PET-fMRI comparisonChristian la Fougere
Department of Nuclear Medicine, Ludwig Maximilians University of Munich, Germany
Neuroimage 50:1589-98. 2010..Real steady-state locomotion seems to use a direct pathway via the primary motor cortex, whereas imagined modulatory locomotion an indirect pathway via a supplementary motor cortex and basal ganglia loop...
F-18-fluoro-2-deoxyglucose positron emission tomography/computed tomography in the follow-up of breast cancer with elevated levels of tumor markersAlexander Robert Haug
Department of Nuclear Medicine, Ludwig Maximilians University of Munich, Germany
J Comput Assist Tomogr 31:629-34. 2007..The value of combined positron emission tomography (PET)/computed tomography (CT) in the follow-up of patients with breast cancer with elevated tumor markers but without proven metastases or local recurrence was assessed...
Re-irradiation in recurrent malignant glioma: prognostic value of [18F]FET-PETMaximilian Niyazi
Department of Radiation Oncology, Ludwig Maximilians University Munich, Marchioninistr 15, 81377, Munich, Germany
J Neurooncol 110:389-95. 2012..Thus, [(18)F]FET-PET kinetics may provide valuable additional prognostic information for treatment decisions...
Irradiation and bevacizumab in high-grade glioma retreatment settingsMaximilian Niyazi
Department of Radiation Oncology, Ludwig Maximilians University Munich, Munich, Germany
Int J Radiat Oncol Biol Phys 82:67-76. 2012..To study the feasibility of reirradiation combined with bevacizumab treatment, the toxicity and treatment outcomes of this approach were analyzed retrospectively...
Improved work-up procedure for the production of [(18)F]flumazenil and first results of its use with a high-resolution research tomograph in human strokeGassan Massaweh
McConnell Brain Imaging Centre, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada
Nucl Med Biol 36:721-7. 2009..18)F-Labeled flumazenil ([(18)F]FZ) provides a potentially useful tracer to investigate those disorders by means of positron emission tomography (PET)...
Functional representation of olfactory impairment in early Alzheimer's diseaseStefan Forster
Department of Nuclear Medicine, Ludwig Maximilian University, Munich, Germany
J Alzheimers Dis 22:581-91. 2010....
Clinical validation of the gated blood pool SPECT QBS processing software in congestive heart failure patients: correlation with MUGA, first-pass RNV and 2D-echocardiographyMarcus Hacker
Department of Nuclear Medicine, University of Munich, Munich, Germany
Int J Cardiovasc Imaging 22:407-16. 2006..Aim of the study was to evaluate a commercially available automated GBPS processing software for EF measurements and wall motion analysis in heart failure patients...
The dopamine transporter and neuroimaging in attention deficit hyperactivity disorderKlaus Henning Krause
Friedrich Baur Institute, Ludwig Maximilians University, Ziemssenstr 1a, D 80336 Munich, Germany
Neurosci Biobehav Rev 27:605-13. 2003..DAT seem to be elevated in non-smoking ADHD patients suffering from the purely inattentive subtype of ADHD as well as in those with the combined or purely hyperactive/impulsive subtype...
PET/CT in malignant melanoma: contrast-enhanced CT versus plain low-dose CTThomas Pfluger
Department of Nuclear Medicine, LMU, Munich, Germany
Eur J Nucl Med Mol Imaging 38:822-31. 2011....
Effects of peripheral vascular intervention on ischemia-modified albuminMarcus Hacker
Department of Nuclear Medicine, University of Munich, Munich, Germany
Coron Artery Dis 18:375-9. 2007....
FET-PET for malignant glioma treatment planningMaximilian Niyazi
Department of Radiation Oncology, Ludwig Maximilians University Munich, Munchen, Germany
Radiother Oncol 99:44-8. 2011....
Bilateral temporal lobe epilepsy confirmed with intracranial EEG in chorea-acanthocytosisBenedikt Bader
Neurologische Klinik und Poliklinik, Ludwig Maximilians Universitat, Marchioninistr 15, 81377 Munchen, Germany
Seizure 20:340-2. 2011....
Radioembolization in patients with hepatic metastases from breast cancerTobias F Jakobs
Department of Radiology, Ludwig Maximilians University of Munich, Campus Grosshadern, Marchioninistrasse 15, 81377 Munich, Germany
J Vasc Interv Radiol 19:683-90. 2008....
Increase of striatal dopamine transmission in first episode drug-naive schizophrenic patients as demonstrated by [(123)I]IBZM SPECTGisela Johanna Elisabeth Schmitt
Department of Psychiatry, Medical Center of the University of Munich, Munich, Germany
Psychiatry Res 173:183-9. 2009....
Molecular imaging of gliomas with PET: opportunities and limitationsChristian la Fougere
Department of Nuclear Medicine, University of Munich Campus Grosshadern, Marchioninistr 15, 81377 Munich, Germany
Neuro Oncol 13:806-19. 2011....
Myocardial perfusion imaging is feasible for infarct size quantification in mice using a clinical single-photon emission computed tomography system equipped with pinhole collimatorsTim Wollenweber
Department of Nuclear Medicine, University of Munich, Munich, Germany
Mol Imaging Biol 12:427-34. 2010..The aim of this study is to evaluate a non-invasive method for measuring myocardial perfusion defect size in mice using a clinical single-photon emission computed tomography system equipped with pinhole collimators (pinhole SPECT)...
Ictal SPECT in Sturge-Weber syndromeOzgur Bilgin
University of Munich, Klinikum Grosshadern Department of Neurology, Germany
Epilepsy Res 78:240-3. 2008..Right orbito-frontal resection and disconnection from corpus callosum resulted in seizure freedom...
