Research Topics
Species | J KukoljaSummaryAffiliation: University of Cologne Country: Germany Publications
|
Detail Information
Publications
Medial temporal lobe dysfunction during encoding and retrieval of episodic memory in non-demented APOE epsilon4 carriersJ Kukolja
Cognitive Neurology Section, Institute of Neuroscience and Medicine INM 3, Research Centre Julich, Julich, Germany
Neuroscience 168:487-97. 2010..These data highlight that preclinical ApoE-related changes in neural activity are not unidirectional but dissociate depending on the memory phase, i.e., encoding or retrieval...
Noradrenergic-glucocorticoid modulation of emotional memory encoding in the human hippocampusJ Kukolja
Department of Psychiatry, University of Bonn, Bonn, Germany
Psychol Med 41:2167-76. 2011..Current rodent models emphasize the joint action of the stress mediators noradrenaline (NE) and cortisol (CORT) in conferring a memory advantage of emotional over neutral stimuli...
Cholinergic stimulation enhances neural activity associated with encoding but reduces neural activity associated with retrieval in humansJuraj Kukolja
Department of Neurology, University Hospital, Cologne University, 50924 Cologne, Germany
J Neurosci 29:8119-28. 2009..Thus, participants who were worse at baseline benefited more from cholinergic stimulation than those who had better baseline values, indicating that a cholinergic deficit contributes to the memory decline even in healthy older subjects...
Modeling a negative response bias in the human amygdala by noradrenergic-glucocorticoid interactionsJuraj Kukolja
Cognitive Neurology Section, Institute of Neuroscience and Biophysics Medicine, Research Centre Juelich, 52425 Juelich, Germany
J Neurosci 28:12868-76. 2008..Our results implicate a causative role of NE-CORT interactions in the emergence of a negative bias of cognitive and emotional functions which is germane in stress-related affective spectrum disorders...
The effect of nicotine on visuospatial attention in chronic spatial neglect depends upon lesion locationS Vossel
Cognitive Neurology Section, Institute of Neuroscience and Medicine INM 3, Research Centre Julich, Julich, Germany
J Psychopharmacol 24:1357-65. 2010..We conclude that in patients with chronic spatial neglect the performance in the location-cueing paradigm can be modulated by a cholinergic stimulant provided that the lesion spares right parietal and temporal cortex...
Ageing-related changes of neural activity associated with spatial contextual memoryJuraj Kukolja
Department of Medicine, Institute of Neuroscience and Biophysics, Research Centre Juelich, Germany
Neurobiol Aging 30:630-45. 2009..Both findings are likely to underlie the contextual memory deficit observed in older subjects...
Human amygdala reactivity is diminished by the β-noradrenergic antagonist propranololR Hurlemann
Department of Psychiatry, University of Bonn, Bonn, Germany
Psychol Med 40:1839-48. 2010....
Neural mechanisms underlying spatial judgements on seen and imagined visual stimuli in the left and right hemifields in menJuraj Kukolja
Institute of Medicine, Cognitive Neurology Group, Research Centre Julich, Germany
Neuropsychologia 44:2846-60. 2006..Overall, our findings converge with neuropsychological data showing that representational and visuospatial neglect do not always co-occur...
Judging the angles formed by visible and imaginary clock hands: a study of hemispatial effects in healthy volunteersJuraj Kukolja
Institute of Medicine, , , Germany
Cortex 40:329-37. 2004..No such operation is required in the perceptual condition where the hands are clearly visible...
Increased cortisol levels in cognitively challenging situations are beneficial in young but not older subjectsJuraj Kukolja
Cognitive Neurology Section, Institute of Neuroscience and Biophysics Medicine INB 3, Research Centre Julich, Julich, Germany
Psychopharmacology (Berl) 201:293-304. 2008..This is also reflected in age-related differences in effects of acute stress on, e.g., episodic memory. Less is known about age-related differences of the cognitive effects of individual stress responses to challenging situations...
K(+)-evoked [(3)H]-norepinephrine release in human brain slices from epileptic and non-epileptic patients is differentially modulated by gabapentin and pinacidilThomas M Freiman
Department of Neurosurgery, Neurocentre, University Hospital, Albert Ludwigs University, Breisacher Strasse 64, D 7106 Freiburg im Breisgau, Germany
Neurosci Res 55:204-10. 2006....
