Jens Kuhn

Summary

Affiliation: University of Cologne
Country: Germany

Publications

  1. doi request reprint Deep brain stimulation in addiction due to psychoactive substance use
    Jens Kuhn
    Department of Psychiatry and Psychotherapy, University Hospital Cologne, Cologne, Germany Electronic address
    Handb Clin Neurol 116:259-69. 2013
  2. pmc Clinical effectiveness of unilateral deep brain stimulation in Tourette syndrome
    J Kuhn
    Department of Psychiatry and Psychotherapy, University of Cologne, Cologne, Germany
    Transl Psychiatry 1:e52. 2011
  3. doi request reprint [Deep brain stimulation in schizophrenia]
    J Kuhn
    Klinik und Poliklinik fur Psychiatrie und Psychotherapie, Klinikum der Universität Köln, Koln
    Fortschr Neurol Psychiatr 79:632-41. 2011
  4. pmc Deep brain stimulation for psychiatric disorders
    Jens Kuhn
    Klinik fur Psychiatrie und Psychotherapie, Klinikum der Universität zu Köln, Germany
    Dtsch Arztebl Int 107:105-13. 2010
  5. doi request reprint Successful deep brain stimulation of the nucleus accumbens in severe alcohol dependence is associated with changed performance monitoring
    Jens Kuhn
    Department of Psychiatry and Psychotherapy, University of Cologne, Germany
    Addict Biol 16:620-3. 2011
  6. doi request reprint Deep brain stimulation as a new therapeutic approach in therapy-resistant mental disorders: ethical aspects of investigational treatment
    Jens Kuhn
    Department of Psychiatry and Psychotherapy, University of Cologne, Kerpener Strasse 62, 50924 Cologne, Germany
    Eur Arch Psychiatry Clin Neurosci 259:S135-41. 2009
  7. doi request reprint Observations on unaided smoking cessation after deep brain stimulation of the nucleus accumbens
    J Kuhn
    Department of Psychiatry and Psychotherapy, University of Cologne, DE 50937 Cologne, Germany
    Eur Addict Res 15:196-201. 2009
  8. doi request reprint Novel KRIT1 mutation and no molecular evidence of anticipation in a family with cerebral and spinal cavernous malformations
    Jens Kuhn
    Department of Psychiatry and Psychotherapy, University of Cologne, Kerpener Strasse 62, Koln, Germany
    Eur Neurol 61:154-8. 2009
  9. doi request reprint Disappearance of self-aggressive behavior in a brain-injured patient after deep brain stimulation of the hypothalamus: technical case report
    Jens Kuhn
    Department of Psychiatry and Psychotherapy, University of Cologne, Cologne, Germany
    Neurosurgery 62:E1182; discussion E1182. 2008
  10. pmc Remission of alcohol dependency following deep brain stimulation of the nucleus accumbens: valuable therapeutic implications?
    Jens Kuhn
    Department of Psychiatry and Psychotherapy, University of Cologne, Kerpener Strasse 62, 50924 Cologne, Germany
    J Neurol Neurosurg Psychiatry 78:1152-3. 2007

Collaborators

Detail Information

Publications26

  1. doi request reprint Deep brain stimulation in addiction due to psychoactive substance use
    Jens Kuhn
    Department of Psychiatry and Psychotherapy, University Hospital Cologne, Cologne, Germany Electronic address
    Handb Clin Neurol 116:259-69. 2013
    ..The objective of this review is to provide an overview of the published results on DBS in addiction, and to discuss whether these preliminary results justify further research, given the novelty of this treatment approach. ..
  2. pmc Clinical effectiveness of unilateral deep brain stimulation in Tourette syndrome
    J Kuhn
    Department of Psychiatry and Psychotherapy, University of Cologne, Cologne, Germany
    Transl Psychiatry 1:e52. 2011
    ..Potential implications and gains of the unilateral approach are discussed...
  3. doi request reprint [Deep brain stimulation in schizophrenia]
    J Kuhn
    Klinik und Poliklinik fur Psychiatrie und Psychotherapie, Klinikum der Universität Köln, Koln
    Fortschr Neurol Psychiatr 79:632-41. 2011
    ....
  4. pmc Deep brain stimulation for psychiatric disorders
    Jens Kuhn
    Klinik fur Psychiatrie und Psychotherapie, Klinikum der Universität zu Köln, Germany
    Dtsch Arztebl Int 107:105-13. 2010
    ..In a number of recently published case series, DBS yielded an impressive therapeutic benefit in patients with medically intractable psychiatric diseases...
  5. doi request reprint Successful deep brain stimulation of the nucleus accumbens in severe alcohol dependence is associated with changed performance monitoring
    Jens Kuhn
    Department of Psychiatry and Psychotherapy, University of Cologne, Germany
    Addict Biol 16:620-3. 2011
    ..Thus, this case supports the hypothesis that DBS of the NAc could have a positive effect on addiction trough a normalization of craving associated with aMCC dysfunction...
  6. doi request reprint Deep brain stimulation as a new therapeutic approach in therapy-resistant mental disorders: ethical aspects of investigational treatment
    Jens Kuhn
    Department of Psychiatry and Psychotherapy, University of Cologne, Kerpener Strasse 62, 50924 Cologne, Germany
    Eur Arch Psychiatry Clin Neurosci 259:S135-41. 2009
    ..It suggests some additional requirements for ethically justifiable therapeutic research employing DBS in psychiatric patients...
  7. doi request reprint Observations on unaided smoking cessation after deep brain stimulation of the nucleus accumbens
    J Kuhn
    Department of Psychiatry and Psychotherapy, University of Cologne, DE 50937 Cologne, Germany
    Eur Addict Res 15:196-201. 2009
    ..We explore whether clinical research on deep brain stimulation (DBS) of the nucleus accumbens (NAc) to treat addiction is justified besides theoretical speculation...
  8. doi request reprint Novel KRIT1 mutation and no molecular evidence of anticipation in a family with cerebral and spinal cavernous malformations
    Jens Kuhn
    Department of Psychiatry and Psychotherapy, University of Cologne, Kerpener Strasse 62, Koln, Germany
    Eur Neurol 61:154-8. 2009
    ..Familial CCM is inherited as an autosomal-dominant trait. There is one study in the literature which reports statistical evidence for anticipation in familial CCM...
  9. doi request reprint Disappearance of self-aggressive behavior in a brain-injured patient after deep brain stimulation of the hypothalamus: technical case report
    Jens Kuhn
    Department of Psychiatry and Psychotherapy, University of Cologne, Cologne, Germany
    Neurosurgery 62:E1182; discussion E1182. 2008
    ..Self-mutilation is a severe symptom of diseases with varying etiologies. It can be observed in the context of mental retardation and after traumatic brain injury. Pharmacological treatment approaches often prove ineffective...
  10. pmc Remission of alcohol dependency following deep brain stimulation of the nucleus accumbens: valuable therapeutic implications?
    Jens Kuhn
    Department of Psychiatry and Psychotherapy, University of Cologne, Kerpener Strasse 62, 50924 Cologne, Germany
    J Neurol Neurosurg Psychiatry 78:1152-3. 2007
    ..Our case report demonstrates the extremely effective treatment of alcohol dependency by means of DBS of the nucleus accumbens and may reveal new prospects in overcoming therapy resistance in dependencies in general...
  11. ncbi request reprint Treatment of symptomatic heterozygous aceruloplasminemia with oral zinc sulphate
    J Kuhn
    Department of Psychiatry and Psychotherapy, University of Cologne, Kerpener Strasse 62, 50924 Cologne, Germany
    Brain Dev 29:450-3. 2007
    ..The present report concerns the beneficial treatment of an 18-year-old girl with extrapyramidal and cerebellar-mediated movement disorder caused by a heterozygous mutation of the ceruloplasmin gene using oral zinc sulphate...
  12. doi request reprint Transient Manic-like Episode Following Bilateral Deep Brain Stimulation of the Nucleus Accumbens and the Internal Capsule in a Patient With Tourette Syndrome
    Jens Kuhn
    Departments of Psychiatry and Psychotherapy and Stereotaxy and Functional Neurosurgery, University of Cologne, Cologne, Germany and Institute of Anatomy I, Heinrich Heine University of Dusseldorf, Dusseldorf, Germany
    Neuromodulation 11:128-31. 2008
    ..Yet, future controlled studies are needed to determine optimal stimulation parameters and to reduce negative side-effects such as transient hypomanic episodes...
  13. ncbi request reprint Parkinson's disease patients with subthalamic stimulation and carers judge quality of life differently
    Catharine J Lewis
    Department of Neurology, University of Cologne, Cologne, Germany
    Parkinsonism Relat Disord 20:514-9. 2014
    ..This disruption could negatively influence the family dynamic, leading to different perceptions of the STN-DBS outcome by patients and caregivers...
  14. doi request reprint Stimulate or degenerate: deep brain stimulation of the nucleus basalis Meynert in Alzheimer dementia
    Katja Hardenacke
    Department of Psychiatry and Psychotherapy, University of Cologne, Cologne, Germany
    World Neurosurg 80:S27.e35-43. 2013
    ..Latest research suggests beneficial effects of DBS in Alzheimer dementia (AD). Because of the high prevalence and the considerable burden of the disease, we endeavored to discuss and reveal the challenges of DBS in AD...
  15. doi request reprint Unilateral deep brain stimulation of the nucleus accumbens in patients with treatment-resistant obsessive-compulsive disorder: Outcomes after one year
    Wolfgang Huff
    Department of Psychiatry and Psychotherapy, University of Cologne, Germany
    Clin Neurol Neurosurg 112:137-43. 2010
    ..Predominantly bilateral stimulation of the anterior limb of the internal capsule was utilized...
  16. doi request reprint Patients' expectations of deep brain stimulation, and subjective perceived outcome related to clinical measures in Parkinson's disease: a mixed-method approach
    Franziska Maier
    Department of Neurology, University of Cologne, Cologne, Germany
    J Neurol Neurosurg Psychiatry 84:1273-81. 2013
    ..To study patients' expectations of subthalamic deep brain stimulation (STN-DBS) and their subjective perceived outcome, by using qualitative and quantitative methods in Parkinson's disease (PD)...
  17. ncbi request reprint Hypomania and mania related to dopamine replacement therapy in Parkinson's disease
    Franziska Maier
    Department of Neurology, University of Cologne, Cologne, Germany Electronic address
    Parkinsonism Relat Disord 20:421-7. 2014
    ..To investigate hypomania and mania related to dopamine replacement therapy (DRT) in Parkinson's disease (PD)...
  18. ncbi request reprint Retropharyngeal tendinitis: a rare differential diagnosis of severe headaches and neck pain
    Simon Harnier
    Neurology, Cologne City Hospitals, Cologne, Germany
    Headache 48:158-61. 2008
    ..The diagnosis is made radiographically by a nearly pathognomonic amorphous calcification anterior to C1-C2 and prevertebral soft tissue swelling. We present a new case of this uncommon condition exhibiting some unusual features...
  19. ncbi request reprint [Frontotemporal dementia]
    Raguna Nagy
    Klinik fur Psychiatrie und Psychotherapie, Universitat zu Koln, Koln
    Med Klin (Munich) 102:816-23. 2007
    ..The estimated prevalence is 15:100,000 in the 45- to 64-year-old population; thus, it appears that the FTD as a cause for so-called presenile dementia is nearly as common as Alzheimer's disease...
  20. doi request reprint Prepulse inhibition of the acoustic startle reflex in high functioning autism
    Sina Kohl
    Department for Psychiatry and Psychotherapy, University Hospital of Cologne, Cologne, North Rhine Westphalia, Germany
    PLoS ONE 9:e92372. 2014
    ..Prepulse inhibition is an operational measure of sensorimotor gating, which indicates an extensive attenuation of the startle reflex that occurs when a startling pulse is preceded by a weaker stimulus, the prepulse...
  21. ncbi request reprint Rapid geographical clustering of wound botulism in Germany after subcutaneous and intramuscular injection of heroin
    Norbert Galldiks
    Department of Neurology, University of Cologne, Kerpener Strasse 62, 50924 Cologne, Germany
    Neurocrit Care 6:30-4. 2007
    ..botulinum intoxication in intravenous drug users (IDUs) within 6 weeks in October and November 2005...
  22. ncbi request reprint Focal hypertrophic pachymeningitis in association with temporal arteritis
    Jens Kuhn
    Kliniken der Stadt Koeln, Krankenhaus Merheim, Neurology, Cologne, Germany
    Headache 44:1045-8. 2004
    ..It is proposed that focal hypertrophic pachymeningitis in itself is the contributing factor to severe headache rather than temporal arteritis alone...
  23. ncbi request reprint Extrapyramidal and cerebellar movement disorder in association with heterozygous ceruloplasmin gene mutation
    Jens Kuhn
    J Neurol 252:111-3. 2005
  24. ncbi request reprint Deep brain stimulation of the nucleus accumbens and the internal capsule in therapeutically refractory Tourette-syndrome
    Jens Kuhn
    J Neurol 254:963-5. 2007