Research Topics
| Christiane KuhlSummaryAffiliation: University of Bonn Country: Germany Publications
| Collaborators
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Detail Information
Publications
Whole-body high-field-strength (3.0-T) MR Imaging in Clinical Practice. Part I. Technical considerations and clinical applicationsChristiane K Kuhl
Department of Radiology, University of Bonn, Sigmund Freud Str 25, 53105 Bonn, Germany
Radiology 246:675-96. 2008..In the second part of the series, clinical applications regarding cardiac, breast, musculoskeletal, abdominopelvic, and pediatric MR and MR spectroscopy will be presented...- MRI for diagnosis of pure ductal carcinoma in situ: a prospective observational studyChristiane K Kuhl
Department of Radiology, University of Bonn, Bonn, Germany
Lancet 370:485-92. 2007..Our aim was to investigate the sensitivity with which ductal carcinoma in situ (DCIS) is diagnosed by mammography and by breast MRI... - Whole-body high-field-strength (3.0-T) MR imaging in clinical practice. Part II. Technical considerations and clinical applicationsChristiane K Kuhl
Department of Radiology, University of Bonn, Sigmund Freud Str 25, Bonn 53105, Germany
Radiology 247:16-35. 2008..Even without published evidence, clinical experience suggests substantial clinical advantages for musculoskeletal and pediatric applications... - Sensitivity encoding for diffusion-weighted MR imaging at 3.0 T: intraindividual comparative studyChristiane K Kuhl
Department of Radiology, University of Bonn, Sigmund Freud Strasse 25, D 53105 Bonn, Germany
Radiology 234:517-26. 2005..0 T can help to improve image quality and confidence in and accuracy of diagnosis of ischemic lesions, compared with DW MR imaging with conventional phase encoding, in patients... - [The "EVA" Trial: Evaluation of the Efficacy of Diagnostic Methods (Mammography, Ultrasound, MRI) in the secondary and tertiary prevention of familial breast cancer. Preliminary results after the first half of the study period]C K Kuhl
Radiologische Universitätsklinik Bonn, Bonn
Rofo 177:818-27. 2005..e., mammography (Mx), high-frequency breast ultrasound (US), and dynamic contrast-enhanced breast (MRI) regarding the early diagnosis of familial (hereditary) breast cancer... - Dynamic bilateral contrast-enhanced MR imaging of the breast: trade-off between spatial and temporal resolutionChristiane K Kuhl
Department of Radiology, University of Bonn, Sigmund Freud Str 25, D 53105 Bonn, Germany
Radiology 236:789-800. 2005..To investigate prospectively the trade-off between temporal and spatial resolution in dynamic contrast material-enhanced bilateral magnetic resonance (MR) imaging of the breast... - [Familial breast cancer: what the radiologist needs to know]C K Kuhl
Radiologische Klinik, Universitatskliniken Bonn
Rofo 178:680-7. 2006..Lastly, an overview is given of the current evidence regarding the effectiveness of the different imaging modalities for early diagnosis of familial and hereditary breast cancer... - Current status of breast MR imaging. Part 2. Clinical applicationsChristiane K Kuhl
Department of Radiology, University of Bonn, Sigmund Freud Str 25, D 53105 Bonn, Germany
Radiology 244:672-91. 2007..A discussion is provided on the many controversies that exist regarding breast MR imaging for preoperative staging and for screening... - Contrast-enhanced MR imaging of the breast at 3.0 and 1.5 T in the same patients: initial experienceChristiane K Kuhl
Department of Radiology, University of Bonn, Sigmund Freud Str 25, 53105 Bonn, Germany
Radiology 239:666-76. 2006..To establish a pulse sequence for dynamic contrast material-enhanced magnetic resonance (MR) imaging of the breast at 3.0 T and to prospectively compare MR imaging at 3.0 T with MR imaging at 1.5 T in the same patients... - Breast MR imaging at 3TChristiane K Kuhl
Department of Radiology, University of Bonn, Sigmund Freud Str, 25, 53105 Bonn, Germany
Magn Reson Imaging Clin N Am 15:315-20, vi. 2007..The specific high-field-induced physical changes and their effects on breast imaging are explained. A short overview is given on the current level of evidence regarding breast MR imaging at higher magnetic fields... - Acute and subacute ischemic stroke at high-field-strength (3.0-T) diffusion-weighted MR imaging: intraindividual comparative studyChristiane K Kuhl
Department of Radiology, University of Bonn, Sigmund Freud Str 25, D 53105 Bonn, Germany
Radiology 234:509-16. 2005..To compare signal-to-noise ratios (SNRs), contrast-to-noise ratios (CNRs), image quality, and confidence in diagnosis between 1.5- and 3.0-T diffusion-weighted (DW) magnetic resonance (MR) imaging of ischemic stroke lesions... - Mammography, breast ultrasound, and magnetic resonance imaging for surveillance of women at high familial risk for breast cancerChristiane K Kuhl
Department of Radiology, University of Bonn, Bonn, Germany
J Clin Oncol 23:8469-76. 2005..To compare the effectiveness of mammography, breast ultrasound, and magnetic resonance imaging (MRI) for surveillance of women at increased familial risk for breast cancer (lifetime risk of 20% or more)... - Prospective multicenter cohort study to refine management recommendations for women at elevated familial risk of breast cancer: the EVA trialChristiane Kuhl
Department of Radiology, University of Bonn, Sigmund Freud Str 25, D 53105 Bonn, Germany
J Clin Oncol 28:1450-7. 2010.... - Do T2-weighted pulse sequences help with the differential diagnosis of enhancing lesions in dynamic breast MRI?C K Kuhl
Department of Radiology, University of Bonn, Germany
J Magn Reson Imaging 9:187-96. 1999..In a contrast-enhancing breast lesion, careful analysis of T2-weighted TSE images can improve differential diagnosis. The accuracy of this criterion varies with age... - Concepts for differential diagnosis in breast MR imagingChristiane K Kuhl
Department of Radiology, University of Bonn, Sigmund Freud Strasse 25, D 53105 Bonn, Germany
Magn Reson Imaging Clin N Am 14:305-28, v. 2006..This article provides an overview on the current status of the diagnosis criteria that are used for differential diagnosis in breast MR imaging and on the diagnostic accuracy that is achievable with breast MR imaging... - [Magnetic resonance imaging in preoperative staging for breast cancer: pros and contras]C K Kuhl
Radiologische Universitätsklinik Bonn, Sigmund Freud Str 25, Bonn
Radiologe 48:358-66. 2008..MRI for staging may only be done in institutions that can also offer an MR-guided tissue sampling, preferably by MR-guided vacuum assisted biopsy, to provide pre-operative histological proof of lesions visible by breast MRI alone... - MR imaging for surveillance of women at high familial risk for breast cancerChristiane K Kuhl
Department of Radiology, University of Bonn, Sigmund Freud Strasse 25, D 53105 Bonn, Germany
Magn Reson Imaging Clin N Am 14:391-402, vii. 2006..It should be considered an integral part of a surveillance program for women at increased familial risk for breast cancer, be it with or without documented mutation of a breast cancer susceptibility gene... - Dynamic image interpretation of MRI of the breastC K Kuhl
Department of Radiology, University of Bonn, Bonn, Germany
J Magn Reson Imaging 12:965-74. 2000..J. Magn. Reson. Imaging 2000;12:965-974... - MR imaging--guided large-core (14-gauge) needle biopsy of small lesions visible at breast MR imaging aloneC K Kuhl
Department of Radiology, University of Bonn, Sigmund Freud Strasse 25, D 53105 Bonn, Germany
Radiology 220:31-9. 2001..To report our experience with magnetic resonance (MR) imaging-guided large-core breast biopsy of lesions visible at breast MR imaging only... - Potential impact of preoperative magnetic resonance imaging of the breast on patient selection for accelerated partial breast irradiationMarietta Kühr
Department of Obstetrics and Gynecology and Center of Integrated Oncology, University of Bonn, Bonn, Germany
Int J Radiat Oncol Biol Phys 81:e541-6. 2011..The objective of this retrospective study was to evaluate the impact of preoperative MRI on patient selection for APBI... - MRI of the pelvis at 3 T: very high spatial resolution with sensitivity encoding and flip-angle sweep technique in clinically acceptable scan timeNuschin Morakkabati-Spitz
Department of Radiology, University of Bonn, Sigmund Freud Strasse 25, 53105, Bonn, Germany
Eur Radiol 16:634-41. 2006..0-T allows spatial resolution to be increased without loss in image quality. We evaluated a T2-weighted turbo spin-echo sequence with high spatial resolution (3T-HR) to determine whether this provides clinically useful pelvic MRI... - The current status of breast MR imaging. Part I. Choice of technique, image interpretation, diagnostic accuracy, and transfer to clinical practiceChristiane Kuhl
Department of Radiology, University of Bonn, Sigmund Freud Str 25, D 53105 Bonn, Germany
Radiology 244:356-78. 2007.... - Does high-field MR imaging have an influence on the classification of patients with clinically isolated syndromes according to current diagnostic mr imaging criteria for multiple sclerosis?M P Wattjes
Department of Radiology Neuroradiology, University Hospital of Bonn, Bonn, Germany
AJNR Am J Neuroradiol 27:1794-8. 2006.... - [Prevalence and type of incidental extramammary findings in MRI of the breast]N Morakkabati-Spitz
Radiologische Universitätsklinik Bonn
Rofo 175:199-202. 2003..To analyze prevalence and type of relevant incidental findings in patients undergoing breast MRI... - [31P-mr spectroscopy of peripheral skeletal musculature under load: demonstration of normal energy metabolites compared with metabolic muscle diseases]W Block
Radiologische Klinik der Universität Bonn
Rofo 168:250-7. 1998..31P-MR spectroscopy of skeletal muscle under exercise was used to obtain the range of normal variation and comparison was made for different neuromuscular diseases... - Sensitivity encoding (SENSE) for high spatial resolution time-of-flight MR angiography of the intracranial arteries at 3.0 TW A Willinek
Department of Radiology, University of Bonn, Germany
Rofo 176:21-6. 2004..0 T using a 1024 imaging matrix and 2) to compare image quality and diagnostic yield with 3.0 T TOF MRA without SENSE... - MR imaging of the prostate at 3.0T with external phased array coil - preliminary resultsN Morakkabati-Spitz
Department of Radiology, University of Bonn, Bonn, Germany
Eur J Med Res 13:287-91. 2008..0T enables to image the prostate without endorectal coil. Aim of this study was to evaluate the diagnostic accuracy of phased array coil 3.0T MRI in patients with suspicion of prostate cancer... - Management of women at high risk for breast cancer: new imaging beyond mammographyC K Kuhl
Department of Radiology, University of Bonn, Sigmund-Freud-Strasse 25, 53105 Bonn, Germany
Breast 14:480-6. 2005..Still, the efficacy of screening even with MRI is unclear in terms of morbidity and mortality, and this lack of evidence must be communicated to women at high genetic risk... - The significance of 99mTc-MAA SPECT/CT liver perfusion imaging in treatment planning for 90Y-microsphere selective internal radiation treatmentHojjat Ahmadzadehfar
Department of Nuclear Medicine, University Hospital Bonn, Bonn, Germany
J Nucl Med 51:1206-12. 2010.... - Influence of preoperative MRI on the surgical management of patients with operable breast cancerMichael Braun
Department of Obstetrics and Gynecology, University of Bonn, Sigmund Freud Street 25, 53105, Bonn, Germany
Breast Cancer Res Treat 111:179-87. 2008..Evaluation of the impact of preoperative magnetic resonance imaging (MRI) of the breast on the clinical management of patients with operable breast cancer (BC)... - Intracranial aneurysms: role of multidetector CT angiography in diagnosis and endovascular therapy planningKarsten Papke
Department of Radiology and Neuroradiology, Klinikum Duisburg, Zu den Rehwiesen 9, D 47055 Duisburg, Germany
Radiology 244:532-40. 2007.... - The "coming of age" of nonmammographic screening for breast cancerChristiane K Kuhl
JAMA 299:2203-5. 2008 - Implications of SENSE MR in routine clinical practiceJohan S van den Brink
Philips Medical Systems, PO Box 10000, 5680 DA Best, The Netherlands
Eur J Radiol 46:3-27. 2003..It is shown that SENSE has opened new horizons in both routine and advanced MR imaging... - Effect of B1 inhomogeneity on breast MR imaging at 3.0 TChristiane K Kuhl
Radiology 244:929-30. 2007 - Mammographic, US, and MR imaging phenotypes of familial breast cancerSimone Schrading
Department of Radiology, University of Bonn, Sigmund Freud Strasse 25, 53105 Bonn, Germany
Radiology 246:58-70. 2008..To prospectively investigate the imaging (mammographic, ultrasonographic [US], magnetic resonance [MR] imaging) features of invasive and intraductal breast cancers in women at familial risk... - MRI evaluation of the contralateral breast in women with recently diagnosed breast cancerConstance D Lehman
University of Washington Medical Center, Seattle, WA 98109, USA
N Engl J Med 356:1295-303. 2007.... - Intra-individual comparison of image contrast in SPIO-enhanced liver MRI at 1.5T and 3.0TMarcus von Falkenhausen
Department of Radiology, University of Bonn, Sigmund Freud Strasse 25, 53105, Bonn, Germany
Eur Radiol 17:1256-61. 2007..0 T as a result of their relaxation properties. The higher susceptibility at 3.0 T compared to 1.5 T does not translate into a stronger signal attenuation of the SPIO enhanced liver parenchyma... - Sensitivity encoding for fast MR imaging of the brain in patients with strokeWinfried A Willinek
Department of Radiology, University of Bonn, Sigmund Freud Strasse 25, D 53105 Bonn, Germany
Radiology 228:669-75. 2003..To evaluate sensitivity encoding (SENSE) technique in a clinical setting for magnetic resonance (MR) imaging in patients who are suspected of having infarction... - Report of the Working Groups on Breast MRI: report of the High-Risk Screening GroupConstance D Lehman
Department of Radiology, University of Washington Medical Center, Seattle 98105-4756, USA
Breast J 10:S9-S12. 2004 - Magnetic resonance imaging of the breast prior to biopsyDavid A Bluemke
Russell H Morgan Department of Radiology and Radiological Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA
JAMA 292:2735-42. 2004..Breast magnetic resonance imaging (MRI) has been shown to have high sensitivity for cancer detection and is increasingly used following mammography to evaluate suspicious breast lesions... - Functional 3.0-T MR assessment of higher cognitive function: are there advantages over 1.5-T imaging?Klaus Hoenig
Department of Radiology, University of Bonn, Sigmund Freud Str 25, D 53105 Bonn, Germany
Radiology 234:860-8. 2005..To compare cortical activation patterns associated with manual motor decision tasks at 1.5- and 3.0-T functional magnetic resonance (MR) imaging... - Three-dimensional dynamic susceptibility-weighted perfusion MR imaging at 3.0 T: feasibility and contrast agent doseChristoph Manka
Department of Radiology, University of Bonn, Sigmund-Freud-Strasse 25, D-53105 Bonn, Germany
Radiology 234:869-77. 2005..Compared with contrast agent dose for 1.5 T imaging, the dose for 3.0 T can be reduced to 0.10 mmol... - Sensitivity encoding (SENSE) for contrast-enhanced 3D MR angiography of the abdominal arteriesMarkus Born
Department of Radiology, University of Bonn, Bonn, Germany
J Magn Reson Imaging 22:559-65. 2005..To assess sensitivity encoding (SENSE) for contrast-enhanced MR angiography (CE-MRA) of the abdominal arteries in comparison with standard MRA protocols... - MRI detection of distinct incidental cancer in women with primary breast cancer studied in IBMC 6883Mitchell D Schnall
Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
J Surg Oncol 92:32-8. 2005..We report on the rate of MRI and mammography detection of foci of distinct incidental cancer in a prospective, multi center trial involving 426 women with confirmed breast cancer at 15 institutions in the US, Canada, and Germany... - Brain tumors: full- and half-dose contrast-enhanced MR imaging at 3.0 T compared with 1.5 T--Initial ExperienceCarsten Krautmacher
Department of Radiology, University of Bonn, Sigmund Freud Strasse 25, D 53105 Bonn, Germany
Radiology 237:1014-9. 2005..0 T) on contrast-to-noise ratio (CNR) at different doses of a T1-shortening contrast agent in patients with contrast-enhancing brain lesions, with 1.5-T MR imaging as a reference standard... - Diagnostic architectural and dynamic features at breast MR imaging: multicenter studyMitchell D Schnall
Department of Radiology, Hospital of the University of Pennsylvania, 3400 Spruce St, Philadelphia, PA 19104, USA
Radiology 238:42-53. 2006..To prospectively determine the prevalence and predictive value of three-dimensional (3D) and dynamic breast magnetic resonance (MR) imaging and contrast material kinetic features alone and as part of predictive diagnostic models... - Adverse events after unenhanced and monomeric and dimeric contrast-enhanced CT: a prospective randomized controlled trialHans H Schild
Department of Radiology, University of Bonn, Hospital and Medical School, Sigmund Freud Str 25, 53105 Bonn, Germany
Radiology 240:56-64. 2006..To prospectively evaluate adverse events (AEs) in patients who underwent nonionic monomeric or dimeric contrast media-enhanced computed tomography (CT) and to compare these effects with AEs in patients who underwent unenhanced CT... - 3.0 T neuroimaging: technical considerations and clinical applicationsWinfried A Willinek
Department of Radiology, University of Bonn, Sigmund Freud Strasse 25, D 53105 Bonn, Germany
Neuroimaging Clin N Am 16:217-28, ix. 2006..5 T to 3.0 T, the number of 3.0 T installations is increasing continuously worldwide. This article reviews the benefits, challenges, and the current knowledge of 3.0 T whole body MR imaging and summarizes its clinical applications... - High-field-strength MR imaging of the liver at 3.0 T: intraindividual comparative study with MR imaging at 1.5 TMarcus M von Falkenhausen
Department of Radiology, University of Bonn, Sigmund Freud Strasse 25, 53105 Bonn, Germany
Radiology 241:156-66. 2006..0 T is comparable to that at 1.5 T with respect to image artifacts, image quality, and diagnostic utility in terms of detection and characterization of focal liver lesions in patients with these lesions... - Female pelvis: MR imaging at 3.0 T with sensitivity encoding and flip-angle sweep techniqueNuschin Morakkabati-Spitz
Department of Radiology, University of Bonn, Sigmund Freud Strasse 25, D 53105 Bonn, Germany
Radiology 241:538-45. 2006..001 for both) with the short imaging time sequence. The fast sequence maintained or improved image quality and thus seems to be advantageous for uncooperative patients... - Randomly segmented central k-space ordering in high-spatial-resolution contrast-enhanced MR angiography of the supraaortic arteries: initial experienceWinfried A Willinek
Department of Radiology, University of Bonn, Sigmund Freud Strasse 25, D 53105 Bonn, Germany
Radiology 225:583-8. 2002..The random order of central k-space acquisition may minimize artifacts in contrast-enhanced 3D MR angiography caused by unstable contrast material opacification at the initiation of sampling... - Dynamic contrast-enhanced breast MR imaging in men: preliminary resultsNuschin Morakkabati-Spitz
Department of Radiology, University of Bonn, Sigmund-Freud-Str 25, D-53105 Bonn, Germany
Radiology 238:438-45. 2006..CONCLUSION: In the small study cohort, the MR imaging features of benign breast diseases and breast cancers in male patients seemed to be comparable to those seen in female patients... - The management of lobular carcinoma in situ (LCIS). Is LCIS the same as ductal carcinoma in situ (DCIS)?Sunil R Lakhani
Molecular and Cellular Pathology, School of Medicine, The University of Queensland, Mayne Medical School, Brisbane, QLD 4006, Australia
Eur J Cancer 42:2205-11. 2006..In this review, the working group on behalf of EUSOMA has attempted to summarise the current thinking and management of this interesting lesion...