Research Topics
Species | Ellen KrautkrämerSummaryAffiliation: University of Heidelberg Country: Germany Publications
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Detail Information
Publications
Hantavirus infection: an emerging infectious disease causing acute renal failureEllen Krautkrämer
Department of Nephrology, University of Heidelberg, Heidelberg, Germany
Kidney Int 83:23-7. 2013..However, the overall symptoms-vascular alterations and leakage-that are responsible for organ failure are characteristic for all diseases caused by hantaviruses...
Polar release of pathogenic Old World hantaviruses from renal tubular epithelial cellsEllen Krautkrämer
Department of Nephrology, University of Heidelberg, Im Neuenheimer Feld 162, 69120, Heidelberg, Germany
Virol J 9:299. 2012..In addition, we analyzed MDCKII cells, an epithelial cell line of a dog kidney, which represents a widely accepted in vitro model of polarized monolayers for their permissiveness for hantavirus infection...
A new permanent cell line derived from the bank vole (Myodes glareolus) as cell culture model for zoonotic virusesSandra S Essbauer
Bundeswehr Institute of Microbiology, Munich, Germany
Virol J 8:339. 2011..Therefore we established and characterized a new cell line, BVK168, using the kidney of a bank vole, Myodes glareolus, the most abundant member of the Arvicolinae trapped in Germany...
Human immunodeficiency virus type 1 Nef protein modulates the lipid composition of virions and host cell membrane microdomainsBritta Brugger
Heidelberg University Biochemistry Center BZH, Heidelberg, Germany
Retrovirology 4:70. 2007..Since Nef modulates the protein composition and function of membrane microdomains we tested here if Nef also has the propensity to alter microdomain lipid composition...
Pathogenic old world hantaviruses infect renal glomerular and tubular cells and induce disassembling of cell-to-cell contactsEllen Krautkrämer
Department of Nephrology, University of Heidelberg, Heidelberg, Germany
J Virol 85:9811-23. 2011..The finding that different renal cell types are susceptible to hantaviral infection and the fact that infection results in the breakdown of cell-to-cell contacts provide useful insights in hantaviral pathogenesis...
Hantavirus causing hemorrhagic fever with renal syndrome enters from the apical surface and requires decay-accelerating factor (DAF/CD55)Ellen Krautkrämer
Department of Nephrology, University of Heidelberg, Im Neuenheimer Feld 162, D 69120 Heidelberg, Germany
J Virol 82:4257-64. 2008..These results demonstrate that the Old World hantaviruses Hantaan and Puumala enter polarized target cells from the apical site and that DAF is a critical cofactor for infection...
Mutations in the BC-loop of the BKV VP1 region do not influence viral load in renal transplant patientsEllen Krautkrämer
Department of Nephrology, University of Heidelberg, Heidelberg, Germany
J Med Virol 81:75-81. 2009..These in vivo results demonstrate that high replication rates which serve as a predictive marker for BKVAN are not caused by altered receptor binding or affinity via mutated BC-loops...
