Axel Kramer

Summary

Affiliation: University of Greifswald
Country: Germany

Publications

  1. ncbi Virucidal activity of a new hand disinfectant with reduced ethanol content: comparison with other alcohol-based formulations
    A Kramer
    Institute of Hygiene and Environmental Medicine, Ernst Moritz Arndt University Greifswald, Walther Rathenau Str 49A, 17489 Greifswald, Germany
    J Hosp Infect 62:98-106. 2006
  2. ncbi Hygienic relevance and risk assessment of antimicrobial-impregnated textiles
    A Kramer
    Institute of Hygiene and Environmental Medicine, Ernst Moritz Arndt University, Greifswald, Germany
    Curr Probl Dermatol 33:78-109. 2006
  3. pmc How long do nosocomial pathogens persist on inanimate surfaces? A systematic review
    Axel Kramer
    Institut fur Hygiene und Umweltmedizin, Ernst Moritz Arndt Universitat, Greifswald, Germany
    BMC Infect Dis 6:130. 2006
  4. ncbi Thyroid disorders in employees of a nuclear power plant
    Stefan Kindler
    Institute of Epidemiology and Social Medicine, Ernst Moritz Arndt University, Greifswald, Germany
    Thyroid 16:1009-17. 2006
  5. pmc Evaluation of the PotoClean(®) decontamination technology for reprocessing of water supply lines in dental units during routine work
    Axel Kramer
    Institute of Hygiene and Environmental Medicine, University Medicine Greifswald, Germany
    GMS Krankenhhyg Interdiszip 7:Doc10. 2012
  6. pmc Purge- and intensive-purge decontamination of dental units contaminated with biofilm
    Axel Kramer
    Institute of Hygiene and Environmental Medicine, University Medicine Greifswald, Germany
    GMS Krankenhhyg Interdiszip 7:Doc11. 2012
  7. pmc Comparison of the antioxidant potential in urine, saliva and skin
    Hicham Benkhai
    Institute of Hygiene and Environmental Medicine, University Medicine Greifswald, Germany
    GMS Krankenhhyg Interdiszip 6:Doc02. 2011
  8. pmc Functional separation of septic and aseptic surgical procedures
    Axel Kramer
    Institute of Hygiene and Environmental Medicine, University Medicine Greifswald, Greifswald, Germany
    GMS Krankenhhyg Interdiszip 6:Doc12. 2011
  9. pmc Decontamination of room air and adjoining wall surfaces by nebulizing hydrogen peroxide
    Torsten Koburger
    Hygiene Nord GmbH, Greifswald, Germany
    GMS Krankenhhyg Interdiszip 6:Doc09. 2011
  10. pmc Comparison of the ActiDes-Blue and CARELA HYDRO-DES technology for the sanitation of contaminated cooling water systems in dental units
    Axel Kramer
    Institute of Hygiene and Environmental Medicine, University Medicine Greifswald, Germany
    GMS Krankenhhyg Interdiszip 7:Doc09. 2012

Detail Information

Publications157 found, 100 shown here

  1. ncbi Virucidal activity of a new hand disinfectant with reduced ethanol content: comparison with other alcohol-based formulations
    A Kramer
    Institute of Hygiene and Environmental Medicine, Ernst Moritz Arndt University Greifswald, Walther Rathenau Str 49A, 17489 Greifswald, Germany
    J Hosp Infect 62:98-106. 2006
    ..32 by 60% propan-2-ol. Testing against feline calicivirus produced a log10 reduction factor of 2.38 by the test formulation; in contrast, the log10 reduction factors with 70% ethanol and 70% propan-1-ol were 0.68 and 0.70, respectively...
  2. ncbi Hygienic relevance and risk assessment of antimicrobial-impregnated textiles
    A Kramer
    Institute of Hygiene and Environmental Medicine, Ernst Moritz Arndt University, Greifswald, Germany
    Curr Probl Dermatol 33:78-109. 2006
    ....
  3. pmc How long do nosocomial pathogens persist on inanimate surfaces? A systematic review
    Axel Kramer
    Institut fur Hygiene und Umweltmedizin, Ernst Moritz Arndt Universitat, Greifswald, Germany
    BMC Infect Dis 6:130. 2006
    ..Inanimate surfaces have often been described as the source for outbreaks of nosocomial infections. The aim of this review is to summarize data on the persistence of different nosocomial pathogens on inanimate surfaces...
  4. ncbi Thyroid disorders in employees of a nuclear power plant
    Stefan Kindler
    Institute of Epidemiology and Social Medicine, Ernst Moritz Arndt University, Greifswald, Germany
    Thyroid 16:1009-17. 2006
    ....
  5. pmc Evaluation of the PotoClean(®) decontamination technology for reprocessing of water supply lines in dental units during routine work
    Axel Kramer
    Institute of Hygiene and Environmental Medicine, University Medicine Greifswald, Germany
    GMS Krankenhhyg Interdiszip 7:Doc10. 2012
    ..In a recent turbine design already after the first intensive decontamination with PotoClean(®) and its continuous use (1 mg Cl/L) no more contamination by bacteria and moulds were detectable...
  6. pmc Purge- and intensive-purge decontamination of dental units contaminated with biofilm
    Axel Kramer
    Institute of Hygiene and Environmental Medicine, University Medicine Greifswald, Germany
    GMS Krankenhhyg Interdiszip 7:Doc11. 2012
    ....
  7. pmc Comparison of the antioxidant potential in urine, saliva and skin
    Hicham Benkhai
    Institute of Hygiene and Environmental Medicine, University Medicine Greifswald, Germany
    GMS Krankenhhyg Interdiszip 6:Doc02. 2011
    ..Conclusion: For the characterization of the AOP in epidemiological studies, we recommend determining the AOPU(urine) and parallel to this, the β-carotene content of the skin...
  8. pmc Functional separation of septic and aseptic surgical procedures
    Axel Kramer
    Institute of Hygiene and Environmental Medicine, University Medicine Greifswald, Greifswald, Germany
    GMS Krankenhhyg Interdiszip 6:Doc12. 2011
    ..Strict adherence to this code of behaviour will allow for efficient functional separation of clean and contaminated surgical procedures without compromising patient safety...
  9. pmc Decontamination of room air and adjoining wall surfaces by nebulizing hydrogen peroxide
    Torsten Koburger
    Hygiene Nord GmbH, Greifswald, Germany
    GMS Krankenhhyg Interdiszip 6:Doc09. 2011
    ..As a load of 10(4) to 10(5) fungal spores is unlikely to occur on pre-cleaned surfaces, the GLOSAIR(TM) 400 can be considered a suitable complementary process for the substantial reduction of fungal contamination...
  10. pmc Comparison of the ActiDes-Blue and CARELA HYDRO-DES technology for the sanitation of contaminated cooling water systems in dental units
    Axel Kramer
    Institute of Hygiene and Environmental Medicine, University Medicine Greifswald, Germany
    GMS Krankenhhyg Interdiszip 7:Doc09. 2012
    ..In comparison, the biofilm was sustainably eliminated through the combined application of CARELA(®) Solvent for Bacterial Slime with subsequent decontamination using CARELA(®) HYDRO-DES...
  11. pmc Impact of the "Guidelines for infection prevention in dentistry" (2006) by the Commission of Hospital Hygiene and Infection Prevention at the Robert Koch-Institute (KRINKO) on hygiene management in dental practices - analysis of a survey from 2009
    Nils Olaf Hübner
    Institute for Hygiene and Environmental Medicine, University Medicine Greifswald, Germany
    GMS Krankenhhyg Interdiszip 7:Doc14. 2012
    ..Doubts about the impact of the guidelines are not backed by evidence...
  12. pmc Polypragmasia in the therapy of infected wounds - conclusions drawn from the perspectives of low temperature plasma technology for plasma wound therapy
    Axel Kramer
    Institute of Hygiene and Environmental Medicine, Ernst Moritz Arndt University, Greifswald, Germany
    GMS Krankenhhyg Interdiszip 3:Doc13. 2008
    ..At the same time, it is desirable to support and increase cell proliferation and granulation capacities. These two aspects might be achieved by using low temperature plasma technology...
  13. pmc Ethical and hygiene aspects of the reprocessing of medical devices in Germany
    Axel Kramer
    Institute for Hygiene and Environmental Medicine, Ernst Moritz Arndt University, Greifswald, Germany
    GMS Krankenhhyg Interdiszip 3:Doc25. 2008
    ..For reprocessing of MDs of the category Critical C the quality assurance must be certified by an accredited certifying body...
  14. pmc Role of disinfection in the Infection Prevention Multibarrier System
    Axel Kramer
    Institute for Hygiene and Environmental Medicine of the Ernst Moritz Arndt University Greifswald, Greifswald, Germany
    GMS Krankenhhyg Interdiszip 2:Doc13. 2007
    ..An indispensable component of primary prevention is assurance of structural and process quality. In turn, disinfection is indispensable for assurance of process quality...
  15. pmc Wound dressings from a hygienic point of view using the example of sorbion sachet S
    Axel Kramer
    Institute for Hygiene and Environmental Medicine, Ernst Moritz Arndt University Greifswald, Germany
    GMS Krankenhhyg Interdiszip 4:Doc11. 2009
    ..The dressing sorbion sachet S is used as an example to examine possible strategies...
  16. pmc Review of indicators for cross-sectoral optimization of nosocomial infection prophylaxis - a perspective from structurally- and process-oriented hygiene
    Nils Olaf Hübner
    Robert Koch Institute Berlin, Germany
    GMS Krankenhhyg Interdiszip 7:Doc15. 2012
    ..This study lays the foundation for hygiene indicator requirements and develops initial concepts for evaluating quality management in hygiene...
  17. pmc Economic comparison of conventional maintenance and electrochemical oxidation to warrant water safety in dental unit water lines
    Sebastian Fischer
    Institute of Hygiene and Environmental Medicine Greifswald, University Medicine, Greifswald, Germany
    GMS Krankenhhyg Interdiszip 7:Doc08. 2012
    ....
  18. pmc Tissue tolerable plasma (TTP) induces apoptosis in pancreatic cancer cells in vitro and in vivo
    Lars Ivo Partecke
    Department of General, Visceral, Thoracic and Vascular Surgery, University Medicine Greifswald, Ernst Moritz Arndt University, Greifswald, Germany
    BMC Cancer 12:473. 2012
    ..The development of non-thermal atmospheric plasmas displaying spectra of temperature within or just above physiological ranges allows biological or medical applications of plasmas...
  19. doi Maintaining health by balancing microbial exposure and prevention of infection: the hygiene hypothesis versus the hypothesis of early immune challenge
    A Kramer
    Institute of Hygiene and Environmental Medicine, University Medicine Greifswald, Germany
    J Hosp Infect 83:S29-34. 2013
    ..Moreover, recent studies have revealed that TH or TReg imbalances in disease may be partially corrected by the administration of helminthic or bacterial extracts...
  20. pmc Norovirus infections in preterm infants: wide variety of clinical courses
    Sven Armbrust
    Department of Neonatology, University Children s Hospital, 17475 Greifswald, Germany
    BMC Res Notes 2:96. 2009
    ..CONCLUSION: Norovirus infection in premature infants shows an impressive pattern of a wide variety of clinical courses. Only the consequent use of different hygienic pattern can lead to elimination of norovirus...
  21. pmc Concentration of the genera Aspergillus, Eurotium and Penicillium in 63-microm house dust fraction as a method to predict hidden moisture damage in homes
    Christoph Baudisch
    State Health and Social Office of Mecklenburg Pomerania, Branch Office Schwerin, Germany
    BMC Public Health 9:247. 2009
    ..Our intent was to develop a house-dust monitoring method to detect hidden moisture damage excluding the influence of outdoor air, accumulated old dust, and dust swirled up from room surfaces...
  22. pmc Effect of lactoperoxidase on the antimicrobial effectiveness of the thiocyanate hydrogen peroxide combination in a quantitative suspension test
    A Welk
    Department of Restorative Dentistry, Periodontology and Endodontology, University of Greifswald, Germany
    BMC Microbiol 9:134. 2009
    ..To evaluate the optimal effectiveness curve, the exposure times were restricted to 1, 3, 5, and 15 min...
  23. ncbi The classification of antiseptic products to be administered to wounds--another borderline case between medicinal products and medical devices?
    A Kramer
    Institute of Hygiene and Environmental Medicine, Ernst Moritz Arndt University, Walther Rathenau Strasse 49a, 17489 Greifswald, Germany
    Int J Clin Pharmacol Ther 44:677-92. 2006
    ....
  24. pmc Quantity of ethanol absorption after excessive hand disinfection using three commercially available hand rubs is minimal and below toxic levels for humans
    Axel Kramer
    Institute of Hygiene and Environmental Medicine, Ernst Moritz Arndt University, Walther Rathenau Str 49A, 17489 Greifswald, Germany
    BMC Infect Dis 7:117. 2007
    ..The aim of this study was to assess if ethanol absorption occurs during hygienic and surgical hand disinfection using three different alcohol-based hand-rubs, and to quantify absorption levels in humans...
  25. doi [Infection prevention check-in and infection prevention check-out to prevent nosocomial infections]
    A Kramer
    Ernst Moritz Arndt Universitat Greifswald, Institut fur Hygiene und Umweltmedizin, Greifswald, Deutschland
    Zentralbl Chir 135:44-8. 2010
    ..In daily practice it is important to follow the fixed instructions, i. e., to ensure a high compliance...
  26. doi [Importance of displacement ventilation for operations and small surgical procedures from the infection preventive point of view]
    A Kramer
    Universitat Greifswald, Institut fur Hygiene und Umweltmedizin, Walther Rathenau Strasse49a, 17489 Greifswald, Deutschland
    Zentralbl Chir 135:11-7. 2010
    ....
  27. doi Antiseptic efficacy and tolerance of tissue-tolerable plasma compared with two wound antiseptics on artificially bacterially contaminated eyes from commercially slaughtered pigs
    A Hammann
    Institute of Hygiene and Environmental Medicine, University of Greifswald, Greifswald, Germany
    Skin Pharmacol Physiol 23:328-32. 2010
    ..To compare the tissue tolerance and efficacy of two wound antiseptics with tissue-tolerable plasma (TTP) on enucleated contaminated eyes from slaughtered pigs in order to draw consequences for the use of TTP on wounds...
  28. ncbi Influence of the antiseptic agents polyhexanide and octenidine on FL cells and on healing of experimental superficial aseptic wounds in piglets. A double-blind, randomised, stratified, controlled, parallel-group study
    A Kramer
    Institute of Hygiene and Environmental Medicine, Ernst Moritz Arndt University, W Rathenau Strasse 49a, DE 17489 Greifswald, Germany
    Skin Pharmacol Physiol 17:141-6. 2004
    ..3 days (no statistical difference to placebo). This may be explained by the better tolerance of polyhexanide in vitro, which was demonstrated with dose and time dependence in cytotoxicity tests on human amnion cells...
  29. ncbi Hand hygiene
    A Kramer
    Institute of Hygiene and Environmental Medicine, Medical Faculty, Ernst Moritz Arndt University, Hainstrasse 26, D 17487 Greifswald, Germany
    Dev Ophthalmol 33:316-27. 2002
  30. ncbi Efficacy and tolerance of selected antiseptic substances in respect of suitability for use on the eye
    A Kramer
    Institute of Hygiene and Environmental Medicine, Medical Faculty, Ernst Moritz Arndt University, Hainstrasse 26, D 17487 Greifswald, Germany
    Dev Ophthalmol 33:117-44. 2002
  31. ncbi Microbial colonization of the eye as target for antiseptics
    A Kramer
    Institute of Hygiene and Environmental Medicine, Medical Faculty, Ernst Moritz Arndt University, Hainstrasse 26, D 17487 Greifswald, Germany
    Dev Ophthalmol 33:2-8. 2002
  32. ncbi Prophylactic indications for eye antiseptics. Prophylaxis against ophthalmia neonatorum
    A Kramer
    Institute of Hygiene and Environmental Medicine, Medical Faculty, Ernst Moritz Arndt University, Hainstrasse 26, D 17487 Greifswald, Germany
    Dev Ophthalmol 33:223-32. 2002
  33. ncbi Requirements concerning antiseptics for periorbital, orbital and intraorbital application. Antimicrobial efficiency
    A Kramer
    Institute of Hygiene and Environmental Medicine, Medical Faculty, Ernst Moritz Arndt University, Hainstrasse 26, D 17487 Greifswald, Germany
    Dev Ophthalmol 33:28-31. 2002
  34. ncbi Antimicrobial efficacy of contact lens care products and critical comment on ISO/FDIS 14729
    A Kramer
    Institute of Hygiene and Environmental Medicine, Medical Faculty, Ernst Moritz Arndt University, Hainstrasse 26, D 17487 Greifswald, Germany
    Dev Ophthalmol 33:343-61. 2002
  35. ncbi Clinical double-blind trial on the dermal tolerance and user acceptability of six alcohol-based hand disinfectants for hygienic hand disinfection
    A Kramer
    Institut fur Hygiene und Umweltmedizin, Ernst Moritz Arndt Universitat Greifswald, Hainstr 26, Germany
    J Hosp Infect 51:114-20. 2002
    ..Sterillium is the only hand disinfectant containing mecetronium etilsulphate which has been shown to have an emolliant effect. Future research should focus on user acceptability in order to improve compliance...
  36. ncbi [Hygienic and dermatologic aspects of hand disinfection and prophylactic skin antisepsis]
    A Kramer
    Institut fur Hygiene und Umweltmedizin, Ernst Moritz Arndt Universitat Greifswald
    Hautarzt 56:743-51. 2005
    ..For all 3 indications, alcohol-based formulations are the agents of choice...
  37. ncbi Antisepsis versus antimicrobial chemotherapy and indications for eye antisepsis
    A Kramer
    Institute of Hygiene and Environmental Medicine, Medical Faculty, Ernst Moritz Arndt University, Hainstrasse 26, D 17487 Greifswald, Germany
    Dev Ophthalmol 33:14-27. 2002
  38. doi Association of socioeconomic status with iodine supply and thyroid disorders in northeast Germany
    Henry Volzke
    Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany
    Thyroid 23:346-53. 2013
    ..This study aims to investigate whether the socioeconomic status is cross-sectionally and longitudinally related to low urinary excretion or thyroid disorders in the population of northeast Germany...
  39. doi Five-year change in morphological and functional alterations of the thyroid gland: the Study of Health in Pomerania
    Henry Volzke
    Institute for Community Medicine, Ernst Moritz Arndt University Greifswald, Greifswald, Germany
    Thyroid 22:737-46. 2012
    ....
  40. doi Survival of bacterial pathogens on paper and bacterial retrieval from paper to hands: preliminary results
    Nils Olaf Hübner
    Institute for Hygiene and Environmental Medicine, Ernst Moritz Arndt University of Greifswald, Greifswald, Germany
    Am J Nurs 111:30-4; quiz 35-6. 2011
    ..Paper is omnipresent on hospital units, but few studies have examined the possible role of paper in the spread of nosocomial pathogens...
  41. ncbi Smoking as a risk factor for thyroid volume progression and incident goiter in a region with improved iodine supply
    Till Ittermann
    Institute for Community Medicine, Ernst Moritz Arndt University, D 17487 Greifswald, Germany
    Eur J Endocrinol 159:761-6. 2008
    ..The aim of this paper was to investigate the association of smoking with thyroid volume progression and incident goiter for different age-strata in a region with improved iodine supply...
  42. doi No association of seropositivity for anti-Borrelia IgG antibody with mental and physical complaints
    Hans Joergen Grabe
    Department of Psychiatry and Psychotherapy, Ernst Moritz Arndt University Greifswald, Germany
    Nord J Psychiatry 62:386-91. 2008
    ..Therefore, clinicians should not overvalue seropositivity for anti-Borrelia IgG as a medical cause for unexplained mental or physical complaints...
  43. ncbi The effect of a polyhexamethylene biguanide mouthrinse compared with a triclosan rinse and a chlorhexidine rinse on bacterial counts and 4-day plaque re-growth
    A Welk
    Department of Operative Dentistry, Periodontology, and Paediatric Dentistry, University of Greifswald, Germany
    J Clin Periodontol 32:499-505. 2005
    ..12% aqueous chlorhexidine solution (B), a commercially available 0.3% triclosan/2.0% polyvinyl methyl ether maleic acid copolymer mouthrinse (Colgate Total Plax) (C), and a negative control placebo rinse (10% ethanol, flavour) (D)...
  44. ncbi Effect of a 1 min hand wash on the bactericidal efficacy of consecutive surgical hand disinfection with standard alcohols and on skin hydration
    Nils Olaf Hübner
    Institute of Hygiene and Environmental Medicine, Ernst Moritz Arndt University Greifswald, Walther Rathenau Str 49A, 17489 Greifswald, Germany
    Int J Hyg Environ Health 209:285-91. 2006
    ..In most surgical theatres, a 1 min or even longer hand wash is routine as part of the pre-operative hand disinfection. But its benefit has recently been seen critically...
  45. doi Interaction of polyhexamethylene biguanide hydrochloride (PHMB) with phosphatidylcholine containing o/w emulsion and consequences for microbicidal efficacy and cytotoxicity
    Gerald Müller
    Institute of Hygiene and Environmental Medicine, Ernst Moritz Arndt University Greifswald, W Rathenau Str 49a, 17487 Greifswald, Germany
    Chem Biol Interact 201:58-64. 2013
    ..Tests of microbicidal efficacy in which the same 0.05% PHMB o/w emulsion was re-used 8 times revealed a drug delivery system activated by the presence of test bacteria...
  46. ncbi Effect of selected wound antiseptics on adult articular cartilage (bovine sesamoid bone) in the presence of Escherichia coli and Staphylococcus aureus
    Gerald Müller
    Institute of Hygiene and Environmental Medicine, University of Greifswald, W Rathenau Str 49a, D 17487 Greifswald, Germany
    J Orthop Res 23:127-33. 2005
    ..Iodophores have no negative feedback on cartilage metabolism, moreover, they stimulate chondrocytes in vitro. Cationic antiseptics are not suited as irrigating solutions...
  47. ncbi Hand rub-associated fire incidents during 25,038 hospital-years in Germany
    Axel Kramer
    Institut fur Hygiene und Umweltmedizin, Ernst Moritz Arndt Universitat Greifswald, Greifswald, Germany
    Infect Control Hosp Epidemiol 28:745-6. 2007
    ..The results underline the safety of using alcohol-based hand rubs in hospitals...
  48. doi High (but not low) urinary iodine excretion is predicted by iodine excretion levels from five years ago
    Till Ittermann
    Institute of Community Medicine, University of Greifswald, Greifswald, Germany
    Ann Nutr Metab 58:335-42. 2011
    ..The aim of the present study was to investigate the relation between iodine-creatinine ratio (ICR) at two measuring points 5 years apart...
  49. doi Antimicrobial efficacy of non-thermal plasma in comparison to chlorhexidine against dental biofilms on titanium discs in vitro - proof of principle experiment
    Ina Koban
    Department of Restorative Dentistry, Periodontology and Endodontology, Unit of Periodontology, Ernst Moritz Arndt University Greifswald, Germany
    J Clin Periodontol 38:956-65. 2011
    ..In this study, we evaluated the effect of three different plasma devices on the reduction of Streptococcus mutans (S. mutans) and multispecies human saliva biofilms...
  50. doi Concentration of bacteria passing through puncture holes in surgical gloves
    Julian Camill Harnoss
    Institute for Hygiene and Environmental Medicine, Ernst Moritz Arndt University, Greifswald, Germany
    Am J Infect Control 38:154-8. 2010
    ..This study measured the concentration of bacteria passing through glove punctures under surgical conditions...
  51. ncbi Effect of a polyhexamethylene biguanide mouthrinse on bacterial counts and plaque
    M Rosin
    Department of Operative Dentistry, Periodontology, and Paediatric Dentistry, School of Dentistry, University of Greifswald, Germany
    J Clin Periodontol 28:1121-6. 2001
    ..12% aqueous solution (C) and the other a commercially available mouthrinse (Skinsept mucosa) diluted to a chlorhexidine concentration of 0.12% (D)...
  52. pmc Antimicrobial efficacy of two surface barrier discharges with air plasma against in vitro biofilms
    Rutger Matthes
    Institute for Hygiene and Environmental Medicine, University Medicine Greifswald, Greifswald, Germany
    PLoS ONE 8:e70462. 2013
    ..It was found that the UV emission is negligibly low. In conclusion, the results support the assumption that air plasma could be an option for therapy of chronic wounds. ..
  53. pmc Does a preceding hand wash and drying time after surgical hand disinfection influence the efficacy of a propanol-based hand rub?
    Nils Olaf Hübner
    Institute of Hygiene and Environmental Medicine, Ernst Moritz Arndt University, Walther Rathenau Str, 49a, 17489 Greifswald, Germany
    BMC Microbiol 6:57. 2006
    ..5 min significantly. But the effect of a 1 min preceding hand wash and the effect of one additional minute for evaporation of the alcohol after its application on the efficacy after a 1.5 min application time has never been studied...
  54. doi Dermal and pulmonary absorption of propan-1-ol and propan-2-ol from hand rubs
    Harald Below
    Institute of Hygiene and Environmental Medicine, Ernst Moritz Arndt University, Greifswald, Germany
    Am J Infect Control 40:250-7. 2012
    ..This study investigated whether absorption of propan-1-ol and propan-2-ol from commercially available hand rubs results in measurable concentrations after use...
  55. pmc Bacterial migration through punctured surgical gloves under real surgical conditions
    Nils Olaf Hübner
    Institute of Hygiene and Environmental Medicine, Ernst Moritz Arndt University, Greifswald, Germany
    BMC Infect Dis 10:192. 2010
    ..The aim of this study was to confirm recent results from a previous study focussing on the development of a method to measure the bacterial translocation through puncture holes in surgical gloves under real surgical conditions...
  56. ncbi In vitro action of combinations of selected antimicrobial agents and adult bovine articular cartilage (sesamoid bone)
    Gerald Müller
    Institute of Hygiene and Environmental Medicine, University of Greifswald, Hainstr 26, D 17487 Greifswald, Germany
    Chem Biol Interact 145:331-6. 2003
    ....
  57. pmc Hygienic safety of reusable tap water filters (Germlyser) with an operating time of 4 or 8 weeks in a haematological oncology transplantation unit
    Georg Daeschlein
    Institute for Hygiene and Environmental Medicine, Germany
    BMC Infect Dis 7:45. 2007
    ..Microbial safe tap water is crucial for the safety of immunosuppressed patients...
  58. pmc The durability of examination gloves used on intensive care units
    Nils Olaf Hübner
    Institute of Hygiene and Environmental Medicine, Ernst Moritz Arndt University, Greifswald, Germany
    BMC Infect Dis 13:226. 2013
    ..Adequate protection, however, depends on intact gloves. The risk of perforation of examination gloves is thought to correlate with duration of wearing, yet, only very few prospective studies have been performed on this issue...
  59. pmc XTT assay of ex vivo saliva biofilms to test antimicrobial influences
    Ina Koban
    Unit of Periodontology, Dental School, University of Greifswald, Greifswald, Germany
    GMS Krankenhhyg Interdiszip 7:Doc06. 2012
    ..Its quick and easy applicability renders it especially suitable for screening...
  60. pmc Effectiveness of alcohol-based hand disinfectants in a public administration: impact on health and work performance related to acute respiratory symptoms and diarrhoea
    Nils Olaf Hübner
    Institute of Hygiene and Environmental Medicine, Walter Rathenau Strasse 49 A 17487 Greifswald, Germany
    BMC Infect Dis 10:250. 2010
    ..Hand disinfection is acknowledged as key element for infection control, but its effect in open, work place settings is unclear...
  61. doi Does response bias influence population studies of thyroid disorders?
    Henry Volzke
    Institute of Community Medicine, Ernst Moritz Arndt University, Walther Rathenau Strasse 48, Greifswald, Germany
    Thyroid 18:873-8. 2008
    ..We investigated the potential role of selection bias for studies performed to monitor the iodine supply and prevalence of thyroid disorders...
  62. ncbi Effects of SCN-/H2O2 combinations in dentifrices on plaque and gingivitis
    M Rosin
    Department of Operative Dentistry, Periodontology and Paediatric Dentistry, University of Greifswald, Germany
    J Clin Periodontol 28:270-6. 2001
    ..A 10-week, double-blind, placebo-controlled clinical study on 140 male subjects was conducted to determine the effect on plaque and gingivitis of 5 dentifrices containing various thiocyanate (SCN-)/hydrogen peroxide (H2O2) combinations...
  63. doi Reduced cytotoxicity of polyhexamethylene biguanide hydrochloride (PHMB) by egg phosphatidylcholine while maintaining antimicrobial efficacy
    Gerald Müller
    Institute of Hygiene and Environmental Medicine, Ernst Moritz Arndt University Greifswald, W Rathenau Str 49a, 17487 Greifswald, Germany
    Chem Biol Interact 190:171-8. 2011
    ..From all tested combinations the o/w emulsions containing 0.05% PHMB proved to be superior in this respect to the aqueous preparation...
  64. pmc Cost comparison of MRSA screening and management - a decision tree analysis
    Andrea Tübbicke
    Institute of Health Care Management, University of Greifswald, Friedrich Loeffler Str, 70, 17489, Greifswald, Germany
    BMC Health Serv Res 12:438. 2012
    ..The practical details of MRSA screenings (who, how, when and where to screen) remain a controversial issue...
  65. pmc Atmospheric pressure plasma: a high-performance tool for the efficient removal of biofilms
    Katja Fricke
    Leibniz Institute for Plasma Science and Technology eV, INP Greifswald, Greifswald, Germany
    PLoS ONE 7:e42539. 2012
    ..Physical plasmas offer a huge potential to inactivate micro-organisms and to remove organic materials through plasma-generated highly reactive agents...
  66. doi Biocompatibility index of antiseptic agents by parallel assessment of antimicrobial activity and cellular cytotoxicity
    Gerald Müller
    Institute of Hygiene and Environmental Medicine, University of Greifswald, W Rathenau Str 49a, D 17487 Greifswald, Germany
    J Antimicrob Chemother 61:1281-7. 2008
    ..To assess the suitability of an antiseptic agent, both the microbicidal activity and the cytotoxic effect must be taken into consideration to derive biocompatible antibacterial agents...
  67. ncbi Antibacterial activity of positive and negative polarity low-voltage pulsed current (LVPC) on six typical Gram-positive and Gram-negative bacterial pathogens of chronic wounds
    Georg Daeschlein
    Institute of Hygiene and Environmental Medicine, Ernst Moritz Arndt University, Greifswald, Germany
    Wound Repair Regen 15:399-403. 2007
    ..59, 75th percentile 0.98) and the lowest for S. epidermidis (median log10 RF 0.20; 25th percentile 0.17, 75th percentile 0.24). Yet, there was no significant difference with positive ES against Gram-positive or Gram-negative organisms...
  68. doi Bacterial burden of worn therapeutic silver textiles for neurodermitis patients and evaluation of efficacy of washing
    G Daeschlein
    Department of Dermatology, Ernst Moritz Arndt University, Greifswald, Germany
    Skin Pharmacol Physiol 23:86-90. 2010
    ..AD patients wearing silver textiles should change their used clothes at least daily and wash them in a washing machine at 60 degrees C...
  69. ncbi Comparative study of in vitro cytotoxicity of povidone-iodine in solution, in ointment or in a liposomal formulation (Repithel) and selected antiseptics
    G Muller
    Institute of Hygiene and Environmental Medicine, Ernst Moritz Arndt University, Greifswald, Germany
    Dermatology 212:91-3. 2006
    ..This phenomenon was not detected using CHex, Oct or PHMB. Povidone-iodine seems to be the most tolerated antiseptic in comparison with CHex, Oct or PHMB...
  70. doi Systemic iodine absorption associated with the use of preoperative ophthalmic antiseptics containing iodine
    Behzad Razavi
    Institute of Hygiene and Environmental Medicine, University Medicine Greifswald, Ernst Moritz Arndt University, Germany
    Cutan Ocul Toxicol 32:279-82. 2013
    ..Therefore, a quantitative measurement of iodine absorption from these antiseptics was performed in patients undergoing elective cataract surgery...
  71. pmc In-vitro analysis of the microbicidal activity of 6 contact lens care solutions
    Claudia Hildebrandt
    Institute of Hygiene and Environmental Medicine, University Medicine Greifswald, Greifswald, Germany
    BMC Infect Dis 12:241. 2012
    ..In 2001, the EN ISO 14729 was introduced to ensure adequate disinfection efficacy of contact lens care solutions, but this norm has recently been criticised...
  72. pmc A three-phase in-vitro system for studying Pseudomonas aeruginosa adhesion and biofilm formation upon hydrogel contact lenses
    Claudia Rändler
    Department of Hygiene and Environmental Medicine, Ernst Moritz Arndt University Greifswald, Greifswald, Germany
    BMC Microbiol 10:282. 2010
    ..Whilst P. aeruginosa has been widely used as a model organism for initial biofilm formation on CLs, in-vitro models that closely reproduce in-vivo conditions have rarely been presented...
  73. ncbi Seropositivity for anti-Borrelia IgG antibody is independently associated with carotid atherosclerosis
    Henry Volzke
    Institute of Epidemiology and Social Medicine, Ernst Moritz Arndt University Greifswald, Walther Rathenau Str 48, D 17487 Greifswald, Germany
    Atherosclerosis 184:108-12. 2006
    ..Various infectious agents are associated with atherosclerosis. This analysis was performed to investigate relation between seropositivity for anti-Borrelia IgG and carotid atherosclerosis...
  74. ncbi Limited efficacy of alcohol-based hand gels
    Axel Kramer
    Institute for Hygiene and Environmental Medicine, University of Greifswald, Greifswald, Germany
    Lancet 359:1489-90. 2002
    ....
  75. ncbi Prophylactic indications for eye antiseptics. Pre-, intra- and postoperative antisepsis in eye surgery
    W Behrens-Baumann
    Department of Ophthalmology, Medical Faculty, Otto von Guericke University, Leipziger Strasse 44, D 39120 Magdeburg, Germany
    Dev Ophthalmol 33:212-22. 2002
  76. ncbi [Antiseptic efficacy and acceptance of Octenisept computed with common antiseptic mouthwashes]
    A Kramer
    Institut fur Hygiene und Umweltmedizin, Ernst Moritz Arndt Universitat Greifswald
    Zentralbl Hyg Umweltmed 200:443-56. 1998
    ..sterile water. A subjective assessment of taste and smell of the mouth rinse solutions concludes the evaluation. Further methodological aspects for a common test guideline for antiseptic mouth rinse solutions are discussed...
  77. pmc Pilot-study on the influence of carrier gas and plasma application (open resp. delimited) modifications on physical plasma and its antimicrobial effect against Pseudomonas aeruginosa and Staphylococcus aureus
    Rutger Matthes
    Institute for Hygiene and Environmental Medicine, University Medicine, Greifswald, Germany
    GMS Krankenhhyg Interdiszip 7:Doc02. 2012
    ..Conclusion: The applied plasma in a "closed system" accumulates bactericidal plasma species and might increase antimicrobial efficacy in clinical settings as in wound management involving multi-drug resistant bacteria...
  78. ncbi Effect of topical 1.25% povidone-iodine eyedrops used for prophylaxis of ophthalmia neonatorum on renal iodine excretion and thyroid-stimulating hormone level
    Ralph Richter
    Department of Neonatology and Pediatric Intensive Care, University of Greifswald, Germany
    J Pediatr 148:401-3. 2006
    ..It is not known whether the alternative topical agent, 1.25% povidone-iodine, can influence thyroid function. In this study, no influence of povidone-iodine on thyroid function was observed...
  79. doi The modified HET-CAM as a model for the assessment of the inflammatory response to tissue tolerable plasma
    Claudia Bender
    Institute of Hygiene and Environmental Medicine, Ernst Moritz Arndt University, Greifswald, Germany
    Toxicol In Vitro 25:530-7. 2011
    ..Furthermore, it is possible to induce defined plasma-inflammations on the chorioallantoic membrane and to determine the anti-inflammatory potential of test substances...
  80. ncbi Evaluation of nitrate influence on thyroid volume of adults in a previously iodine-deficient area
    Harald Below
    Institute of Hygiene and Environmental Medicine, Ernst Moritz Arndt University, Walther Rathenau Strasse 49a, 17489 Greifswald, Germany
    Int J Hyg Environ Health 211:186-91. 2008
    ..The aim of the present study was to analyze the influence of nitrate as a possible alimentary goitrogen on thyroid volume in a previously iodine-deficient area...
  81. ncbi In vitro assay for the screening of the plaque-reducing activity of antimicrobial agents
    Frank Albert Pitten
    Institute of Hygiene and Environmental Medicine, Ernst Moritz Arndt University, Greifswald, Germany
    Arzneimittelforschung 53:182-7. 2003
    ..Therefore, the authors conclude that the present in vitro assay is a quick and cost-effective model to screen the activity of antimicrobial agents against bacteria grown in biofilms...
  82. ncbi New aspects of the tolerance of the antiseptic povidone-iodine in different ex vivo models
    A Kramer
    Institute of Hygiene and Environmental Medicine, Ernst Moritz Arndt University, Greifswald, Germany
    Dermatology 204:86-91. 2002
    ..The synthesis of proteoglycans in articular cartilage of bovine sesamoid bones was increased after application of 5% (v/v) PVP-I without any increase in catabolism revealing possibilities for the use as irrigation solution in the joint...
  83. ncbi Requirements and infection prophylaxis for internally cooled implant drills
    P Proff
    Clinic for Orthodontics and Preventive and Paediatric Dentistry, University of Greifswald Dental School, Greifswald, Germany
    Folia Morphol (Warsz) 65:34-6. 2006
    ..Internally cooled drills can be successfully disinfected by means of this hygienic procedure routinely used in dental practice and no source of infection is created...
  84. ncbi Susceptibility to diphtheria in adults: prevalence and relationship to gender and social variables
    H Volzke
    Institute of Epidemiology and Social Medicine, Ernst Moritz Arndt University Greifswald, Greifswald, Germany
    Clin Microbiol Infect 12:961-7. 2006
    ..Women lacked seroprotection more often than men, which might be explained, in part, by gender-specific immune responses following vaccination. There is a need for information campaigns to improve public awareness of these problems...
  85. ncbi Efficacy and safety of silver textile in the treatment of atopic dermatitis (AD)
    M Juenger
    Department of Dermatology, Ernst Moritz Arndt University, Greifswald, Germany
    Curr Med Res Opin 22:739-50. 2006
    ..Because of their antiseptic action, silver-coated textiles suppress S. aureus colonization and toxin formation, thus damping the inflammatory reaction...
  86. ncbi Inverse association between periodontitis and respiratory allergies
    N Friedrich
    Institute of Epidemiology and Social Medicine, Ernst Moritz Arndt University Greifswald, Germany
    Clin Exp Allergy 36:495-502. 2006
    ..Periodontitis is an infection with systemic effects and a high prevalence among adults. In the aetiology of allergic diseases the hygiene hypothesis claims that infections in early infancy may protect against allergic diseases...