Research Topics
| Hans C KortingSummaryAffiliation: University of Munich Country: Germany Publications
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Detail Information
Publications
Different skin thinning potential of equipotent medium-strength glucocorticoidsHans Christian Korting
Klinik und Poliklinik fur Dermatologie und Allergologie, Ludwig Maximilians Universitat, Munich, Germany 80337
Skin Pharmacol Appl Skin Physiol 15:85-91. 2002..Prednicarbate is a topical glucocorticoid with an improved benefit/risk ratio, as it causes less skin atrophy than the equipotent betamethasone 17-valerate...- [Fungi overall! Skin and mucosal mycoses and their treatment]Hans C Korting
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Pharm Unserer Zeit 32:130-7. 2003 
The secreted aspartyl proteinases Sap1 and Sap2 cause tissue damage in an in vitro model of vaginal candidiasis based on reconstituted human vaginal epitheliumMartin Schaller
Department of Dermatology and Allergology, University of Munich, Germany
Infect Immun 71:3227-34. 2003..In contrast the vaginopathic potential of mutants lacking SAP3 or SAP4 to SAP6 was not reduced compared to wild-type cells. These data provide further evidence for a crucial role of Sap1 and Sap2 in C. albicans vaginal infections...- Effect of antimycotic agents on the activity of aspartyl proteinases secreted by Candida albicansMartin Schaller
Department of Dermatology and Allergology, University of Munich, Frauenlobstr 9 11, D 80337 Munich, Germany
J Med Microbiol 52:247-9. 2003..001). These results point to a multiple effect of this antimycotic agent and might explain the reduced adherence of C. albicans to human epithelial cells at subinhibitory doses... - Cytokine expression induced by Candida albicans in a model of cutaneous candidosis based on reconstituted human epidermisMartin Schaller
Department of Dermatology and Allergology, University of Munich, Germany
J Med Microbiol 51:672-6. 2002..These immunomodulatory and morphological similarities might reflect a common pathogenesis factor in both diseases... - Infection of human oral epithelia with Candida species induces cytokine expression correlated to the degree of virulenceMartin Schaller
Department of Dermatology and Allergology, Ludwig Maximilians University Munich, Germany
J Invest Dermatol 118:652-7. 2002.... - The crystal structure of the secreted aspartic proteinase 3 from Candida albicans and its complex with pepstatin AClaudia Borelli
Department of Dermatology and Allergy, Ludwig Maximilian University of Munich, Frauenlobstr 9 11, 80337 Munich, Germany
Proteins 68:738-48. 2007..Inhibitor binding causes active site closure by the movement of a flap segment. Comparison of the structures of Sap3 and Sap2 identifies elements responsible for the specificity of each isoenzyme... - [Grover's disease following hemodialysis in a patient with renal failure]Martina Moderer
Klinik und Poliklinik für Dermatologie und Allergologie der Universität München
J Dtsch Dermatol Ges 2:203-5. 2004..There are only few case reports in the literature describing Grover's disease occurring during hemodialysis treatment. All such previous patients have been men; ours is the first woman... - [Comparison of activity of different topical corticosteroid creams and ointments using a vasoconstriction assay: superiority of hydrocortisone butyrate over hydrocortisone]Hans Christian Korting
Klinik und Poliklinik fur Dermatologie und Allergologie, Klinikum der Universitat Munchen, Germany
J Dtsch Dermatol Ges 3:348-53. 2005..Topical corticosteroids are the treatment of choice for numerous inflammatory or hyperproliferative skin diseases. The vasoconstriction assay is suitable to determinate corticosteroid activity... - Cyproterone acetate loading to lipid nanoparticles for topical acne treatment: particle characterisation and skin uptakeJana Stecová
Institut fur Pharmazie, Freie Universitat Berlin, Konigin Luise Strasse 2 4, D 14195, Berlin, Germany
Pharm Res 24:991-1000. 2007..To improve skin penetration of the poorly absorbed drug, we intended to identify the active moiety and to load it to particulate carrier systems... - Hydroxyethyl starch-induced itch: relevance of light microscopic analysis of semi-thin sections and electron microscopyStefanie Kamann
Clinic and Polyclinic for Dermatology and Allergology, Ludwig Maximilian University, Munich, Germany
J Dtsch Dermatol Ges 5:204-8. 2007..Our aim was to compare electron microscopic search for HES deposits with other techniques... - [Cellulite--the greatest skin problem in healthy people? An approach]Tatjana Pavicic
Klinik und Poliklinik fur Dermatologie und Allergologie, Klinikum der Universitat Munchen, Germany
J Dtsch Dermatol Ges 4:861-70. 2006..The latter approach has been evidence-based with respect to caffeine liposomal cream and retinol cream... - [Topical skin therapy with glucocorticoids--therapeutic index]Thomas Luger
J Dtsch Dermatol Ges 2:629-34. 2004 - Xerosis and callus formation as a key to the diabetic foot syndrome: dermatologic view of the problem and its managementTatjana Pavicic
Klinik und Poliklinik fur Dermatologie und Allergologie, Klinikum der Ludwig Maximilians Universität, D 80337 München, Germany
J Dtsch Dermatol Ges 4:935-41. 2006..The most important therapeutic goals are optimal control of the diabetes mellitus, relieving pressure points and avoiding or reducing callus formation... - Tinea capitisClaus Seebacher
J Dtsch Dermatol Ges 4:1085-91. 2006 - [Oral candidiasis]Dieter Reinel
Bundeswehrkrankenhaus Hamburg, Abt. f. Dermatologie, Venerologie und Allergologie
J Dtsch Dermatol Ges 2:874-6. 2004 - [Use of Lactobacillus as a probiotic factor to treat urogenital and intestinal infections as well as to prevent and treat allergic diseases]Kathrin Merk
Klinikum der Universitat Munchen, Klinik und Poliklinik für Dermatologie und Allergologie Innenstadt
J Dtsch Dermatol Ges 2:752-7. 2004..The preventive and therapeutic effect of lactobacilli applies to diarrhoea and urogenital infections in particular. Lactobacilli also seem to have a protective influence on the development and treatment of atopic disease... - Sphingosine-1-phosphate signaling and the skinThomas Herzinger
Klinik und Poliklinik fur Dermatologie und Allergologie, Ludwig Maximilian University, Munich, Germany
Am J Clin Dermatol 8:329-36. 2007..Topical use of S1P and other sphingosine compounds is also under investigation, particularly for the treatment of acne vulgaris... - Improved differentiation of benign and malignant lymphadenopathy in patients with cutaneous melanoma by contrast-enhanced color Doppler sonographyMonika Hildegard Schmid-Wendtner
Department of Dermatology and Allergology, Ludwig Maximilians University, Frauenlobstr 9 11, D 80337 Munich, Germany
Arch Dermatol 138:491-7. 2002.... - Ciclopirox olamine treatment affects the expression pattern of Candida albicans genes encoding virulence factors, iron metabolism proteins, and drug resistance factorsMarkus Niewerth
Robert Koch-Institut, 13353 Berlin, Germany
Antimicrob Agents Chemother 47:1805-17. 2003..Furthermore, neither the expression of certain multiple-drug resistance genes nor other resistance mechanisms caused C. albicans resistance to this drug even after long-term exposure... - Retinoids in the treatment of skin aging: an overview of clinical efficacy and safetySiddharth Mukherjee
Department of Pharmacology, Bombay College of Pharmacy, Kalina, Santacruz (E, Mumbai, India
Clin Interv Aging 1:327-48. 2006..However, more elaborate clinical studies are required to confirm their advantage in the delivery of topical retinoids... - Comparative study of 2% sertaconazole solution and cream formulations in patients with tinea corporis, tinea pedis interdigitalis, or a corresponding candidosisClaudia Borelli
Department of Dermatology and Allergology, Ludwig Maximilian University, Munich, Germany
Am J Clin Dermatol 8:371-8. 2007..Based on the results of numerous preclinical and clinical studies, sertaconazole can be considered a safe and effective drug for the treatment of fungal skin infections... - Oxygen accessibility and iron levels are critical factors for the antifungal action of ciclopirox against Candida albicansHans-Christian Sigle
, , , , D-14195 Berlin, Germany
J Antimicrob Chemother 55:663-73. 2005..CONCLUSIONS: These data indicate that metabolic activity, oxygen accessibility and iron levels are critical parameters in the mode of action of ciclopirox olamine... - Comparable efficacy and safety of various topical formulations of terbinafine in tinea pedis irrespective of the treatment regimen: results of a meta-analysisHans Christian Korting
Klinik und Poliklinik fur Dermatologie und Allergologie, Ludwig Maximilians Universitat Munchen, Munich, Germany
Am J Clin Dermatol 8:357-64. 2007.... - Lactobacilli - bacteria-host interactions with special regard to the urogenital tractKathrin Merk
Klinikum der Universitat Munchen, Klinik und Poliklinik für Dermatologie und Allergologie Innenstadt, Frauenlobstr 9 11, D 8033 7 München, Germany
Int J Med Microbiol 295:9-18. 2005..This review is aimed to present and discuss results concerning interactions of lactobacilli and immune system or epithelial cells with focus to urogenital mucosa... - [Maintenance treatment and early intervention--the new paradigm in the management of atopic eczema]Hans Christian Korting
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J Dtsch Dermatol Ges 3:519-23. 2005 - OnychomycosisClaus Seebacher
Dresden, Germany
J Dtsch Dermatol Ges 5:61-6. 2007 - Human epithelial cells establish direct antifungal defense through TLR4-mediated signalingGunther Weindl
Department of Dermatology, Eberhard Karls University of Tubingen, Tubingen, Germany
J Clin Invest 117:3664-72. 2007.... - [Dermatological guideline efforts for 2007 in perspective]Hans Christian Korting
J Dtsch Dermatol Ges 5:1-3. 2007 - Toll-like receptors and innate antifungal responsesAlexander Roeder
Department of Dermatology, Ludwig-Maximilians-University, 80337 Munich, Germany
Trends Microbiol 12:44-9. 2004.... - Toll-like receptors as key mediators in innate antifungal immunityAlexander Roeder
Department of Dermatology and Allergology, Ludwig-Maximilian University, Munich, Germany
Med Mycol 42:485-98. 2004..Recent evidence further suggests that TLRs cooperate with other immune receptors involved in fungal recognition and that the selective induction of adaptor proteins finally leads to distinct signalling events upon fungal challenge... - Human defensinsJosef Johann Schneider
Klinik und Poliklinik fur Dermatologie und Allergologie, Ludwig Maximilians Universitat Munchen, Frauenlobstrasse 9 11, 80337 Munich, Germany
J Mol Med (Berl) 83:587-95. 2005..Its bactericidal activity against P. aeruginosa is stronger than that of the other known beta-defensins. Here we present an overview of human antimicrobial peptides with some emphasis on their antifungal properties... - Peroxisome proliferator-activated receptors and their ligands: entry into the post-glucocorticoid era of skin treatment?Gunther Weindl
Department of Dermatology, University of Tubingen, Tubingen, Germany
Drugs 65:1919-34. 2005..Nonetheless, PPARs seem to have significant potential as therapeutic targets in skin inflammatory disorders... - [Tinea capitis]Claus Seebacher
J Dtsch Dermatol Ges 2:462-8. 2004 - Individual acid aspartic proteinases (Saps) 1-6 of Candida albicans are not essential for invasion and colonization of the gastrointestinal tract in miceMarianne Kretschmar
, , Theodor-Kutzer-Ufer 1-3, D-68167 Mannheim, Germany
Microb Pathog 32:61-70. 2002..We conclude that although Saps were produced, individual Saps were not indispensable factors for virulence during gastrointestinal infection of mice... - Receptor-selective retinoids for psoriasis: focus on tazaroteneGunther Weindl
Department of Dermatology, University of Tubingen, Tubingen, Germany
Am J Clin Dermatol 7:85-97. 2006..Moreover, the major drawback of oral tazarotene is teratogenicity, which may limit its use in female patients. Further studies evaluating long-term clinical outcomes with oral tazarotene and its use in combination therapies are awaited... - Reconstructed human epidermis for skin absorption testing: results of the German prevalidation studyMonika Schäfer-Korting
Freie Universitat Berlin, Institut fur Pharmazie, Konigin Luise Strasse 2 4, 14195 Berlin, Germany
Altern Lab Anim 34:283-94. 2006..Long and variable lag times, which are a matter of concern when using human and pig skin, did not occur with RHE. Due to the successful transfer of the protocol, it is now in the validation process... - The use of reconstructed human epidermis for skin absorption testing: Results of the validation studyMonika Schäfer-Korting
Freie Universitat Berlin, Institut fur Pharmazie, Berlin, Germany
Altern Lab Anim 36:161-87. 2008..Thus, the RHE models, EPISKIN, EpiDerm and SkinEthic, are appropriate alternatives to human and pig skin, for the in vitro assessment of the permeation and penetration of substances when applied as aqueous solutions...