Genomes and Genes
Affiliation: University Medical Center Hamburg-Eppendorf
- Clinical and molecular features in patients with atypical teratoid rhabdoid tumor or malignant rhabdoid tumorUwe Kordes
Department of Pediatric Hematology and Oncology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
Genes Chromosomes Cancer 49:176-81. 2010..001). Patients with germline mutation of SMARCB1 manifest at an early age and have a very high risk for progression which has to be considered with respect to the outcome of further treatment studies...
- Neonatal cholestasis and glucose-6-P-dehydrogenase deficiencyUwe Kordes
Department of Pediatric Hematology and Oncology, University Medical Center Eppendorf, Hamburg, Germany
Pediatr Blood Cancer 54:758-60. 2010..A detailed work-up failed to reveal other specific factors contributing to cholestasis. Severe hemolytic disease of the newborn may cause cholestasis even in the absence of associated primary hepato-biliary disease...
- Germline nonsense mutation and somatic inactivation of SMARCA4/BRG1 in a family with rhabdoid tumor predisposition syndromeReinhard Schneppenheim
Department of Pediatric Hematology and Oncology, University Medical Center Hamburg Eppendorf, Martinistrasse 52, Hamburg, Germany
Am J Hum Genet 86:279-84. 2010..SMARCA4 is thus a second member of the SWI/SNF complex involved in cancer predisposition. Its general involvement in other tumor entities remains to be established...
- Supra- and infratentorial pediatric ependymomas differ significantly in NeuN, p75 and GFAP expressionChristian Hagel
Institute of Neuropathology, University Medical Center Hamburg Eppendorf, Martinistr 52, 20246, Hamburg, Germany
J Neurooncol 112:191-7. 2013..However, because of the small sample size the results are of preliminary nature and replication in a larger cohort would be desirable...
- Sox group E gene expression distinguishes different types and maturational stages of glial cells in developing chick and mouseUwe Kordes
Department of Pediatric Hematology and Oncology, University Hospital Hamburg Eppendorf, Martinistr 52, 20246 Hamburg, Germany
Brain Res Dev Brain Res 157:209-13. 2005..Sox8 appeared both in oligodendrocytes and astrocytes, Sox9 was more abundant in astrocytes and Sox10 was restricted to later stages of oligodendrocyte development...