Research Topics
Genomes and GenesSpecies | Kerstin KonradSummaryAffiliation: University Hospital Country: Germany Publications
| Collaborators
|
Detail Information
Publications
Differential effects of methylphenidate on attentional functions in children with attention-deficit/hyperactivity disorderKerstin Konrad
Techinical University of Aachen, Germany
J Am Acad Child Adolesc Psychiatry 43:191-8. 2004..To examine the effects of methylphenidate on different attentional functions and behavior in children with attention-deficit/hyperactivity disorder (ADHD)...
Response to emotional stimuli in boys with conduct disorderSabine C Herpertz
Department of Psychiatry and Psychotherapy, Rostock University, Gehlsheimer Str 20, D 18147 Rostock, Germany
Am J Psychiatry 162:1100-7. 2005..The purpose of this study was to examine autonomic arousal in boys with conduct disorder, comorbid conduct disorder and ADHD, and ADHD only...
Familiality and molecular genetics of attention networks in ADHDKerstin Konrad
Child Neuropsychology Section, Department of Child and Adolescent Psychiatry of RTWH Aachen, Aachen, Germany
Am J Med Genet B Neuropsychiatr Genet 153:148-58. 2010....
[Attention deficit hyperactivity syndrome throughout the life span]K Konrad
LFG Klinische Neuropsychologie des Kindes und Jugendalters, Klinik fur Kinder und Jugendpsychiatrie und psychotherapie, Universitatsklinikum, 52074 Aachen
Nervenarzt 80:1302-11. 2009..Multimodal treatment options including stimulants, antidepressants and behavioral therapy play a fundamental role in the management of ADHD across the life span...
Dysfunctional attentional networks in children with attention deficit/hyperactivity disorder: evidence from an event-related functional magnetic resonance imaging studyKerstin Konrad
Department of Child and Adolescent Psychiatry, University Hospital Aachen, Germany
Biol Psychiatry 59:643-51. 2006..Although there is evidence for attentional dysfunction in children with attention deficit/hyperactivity disorder (ADHD), the neural basis of these deficits remains poorly understood...
Long-term effects of methylphenidate on neural networks associated with executive attention in children with ADHD: results from a longitudinal functional MRI studyKerstin Konrad
Child Neuropsychology Section, Department of Child and Adolescent Psychiatry, University Hospital Aachen, Germany
J Am Acad Child Adolesc Psychiatry 46:1633-41. 2007....
Development of attentional networks: an fMRI study with children and adultsKerstin Konrad
Department of Child and Adolescent Psychiatry, University Hospital Aachen, D 52074 Aachen, Germany
Neuroimage 28:429-39. 2005....
Clinical evaluation of subjective and objective changes in motor activity and attention in children with attention-deficit/hyperactivity disorder in a double-blind methylphenidate trialKerstin Konrad
Department of Child and Adolescent Psychiatry, University Hospital Aachen, Aachen, Germany
J Child Adolesc Psychopharmacol 15:180-90. 2005..Thus, for clinical practice, it should be taken into account that behavior ratings of ADHD symptoms seemed to be predominantly influenced by changes of motor activity...
Is the ADHD brain wired differently? A review on structural and functional connectivity in attention deficit hyperactivity disorderKerstin Konrad
Child Neuropsychology Section, Department of Child and Adolescent Psychiatry and Psychotherapy, University Hospital of the RWTH Aachen, Germany
Hum Brain Mapp 31:904-16. 2010....
Cognitive flexibility in juvenile anorexia nervosa patients before and after weight recoveryKatharina Bühren
Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital of the RWTH Aachen, Neuenhofer Weg 21, 52074 Aachen, Germany
J Neural Transm 119:1047-57. 2012..One could speculate that the shorter duration of illness and the incomplete maturation of the prefrontal cortices contribute to these findings...
Neural mechanisms of empathy in adolescents with autism spectrum disorder and their fathersEllen Greimel
Child Neuropsychology Section, Department of Child and Adolescent Psychiatry and Psychotherapy, University Hospital of the RWTH Aachen, Neuenhofer Weg 21, Germany
Neuroimage 49:1055-65. 2010..Moreover, the findings provide evidence that both aberrant neural face and mirroring mechanisms are implicated in empathy impairments in ASD...
Atypical brain responses to reward cues in autism as revealed by event-related potentialsGregor Kohls
Child Neuropsychology Section, Department of Child and Adolescent Psychiatry and Psychotherapy, RWTH Aachen University, Aachen, Germany
J Autism Dev Disord 41:1523-33. 2011..Thus, our findings suggest a general reward processing deficit rather than a specific social reward dysfunction in autism...
Neural integration of iconic and unrelated coverbal gestures: a functional MRI studyAntonia Green
Department of Psychiatry and Psychotherapy Section of Experimental Psychopathology, RWTH Aachen University, Aachen, Germany
Hum Brain Mapp 30:3309-24. 2009..The distinct processing streams (visual versus linguistic/spatial) are interpreted in terms of "auxiliary systems" allowing the integration of speech and gesture in the left temporo-occipital region...
Morphometric brain abnormalities in boys with conduct disorderThomas Huebner
Department of Child and Adolescent Psychiatry and Psychotherapy, University Hospital, RWTH Aachen, Germany
J Am Acad Child Adolesc Psychiatry 47:540-7. 2008..Although there have been several neuroimaging studies on morphometric differences in adults with antisocial personality disorder, little is known about structural brain aberrations in boys with CD...
Coherent motion processing in autism spectrum disorder (ASD): an fMRI studySarah Brieber
Child Neuropsychology Section, Department of Child and Adolescent Psychiatry and Psychotherapy, University Hospital of the RWTH Aachen, D 52074 Aachen, Germany
Neuropsychologia 48:1644-51. 2010..This might reflect differences in the perception of visual stimuli in ASD, which possibly result in impaired integration of motion signals...
Neurocognitive performance in children with ADHD and OCDTimo D Vloet
Department of Child and Adolescent Psychiatry and Psychotherapy, Medical Faculty, RWTH Aachen University, Aachen, Germany
J Abnorm Child Psychol 38:961-9. 2010..This double dissociation highlights the distinct cognitive dysfunctions associated with ADHD and OCD and might possibly point to different neural abnormalities in both disorders...
Effects of the DRD4 genotype on neural networks associated with executive functions in children and adolescentsSusanne Gilsbach
Department of Child and Adolescent Psychiatry and Psychotherapy, Medical Faculty, RWTH Aachen University, Germany
Dev Cogn Neurosci 2:417-27. 2012..Our results indicate that the 7-repeat allele influences both regional brain activation patterns as well as connectivity patterns between neural networks of incompatibility and temporal processing...
Impact of anxiety disorders on attentional functions in children with ADHDTimo D Vloet
Department of Child and Adolescent Psychiatry, Medical Faculty, RWTH Aachen University, D 52074 Aachen, Germany
J Affect Disord 124:283-90. 2010..This is the first study that examines the influence of anxiety disorders (ANX) on ADHD in a model-oriented approach including selectivity and intensity parameters of attention...
Differential patterns of disordered eating in subjects with ADHD and overweightChristine Wilhelm
Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Clinics, RWTH Aachen University, Aachen, Germany
World J Biol Psychiatry 12:118-23. 2011..Despite growing evidence for an association between overweight and attention-deficit/hyperactivity disorder (ADHD), still little is known about the mechanisms underlying this relationship...
Sex differences in attentional performance and their modulation by methylphenidate in children with attention-deficit/hyperactivity disorderThomas Gunther
Child Neuropsychology Section, Department of Child and Adolescent Psychiatry, University Hospital of the RWTH Aachen, Aachen, Germany
J Child Adolesc Psychopharmacol 20:179-86. 2010....
Associations between trait anxiety and psychopathological characteristics of children at high risk for severe antisocial developmentGeorg G Polier
Department of Child and Adolescent Psychiatry and Psychotherapy, Medical Faculty, RWTH Aachen University, Germany
Atten Defic Hyperact Disord 2:185-93. 2010..Anxiety should be considered carefully in children with ADHD and the early-onset subtype of CD in order to optimize current therapeutic interventions...
Modulation of attention-deficit/hyperactivity disorder symptoms by short- and long-acting methylphenidate over the course of a dayThomas Gunther
Child Neuropsychology Section, Department of Child and Adolescent Psychiatry, University Hospital of the RWTH Aachen, Aachen, Germany
J Child Adolesc Psychopharmacol 22:131-8. 2012..Thus, our data suggest that it is crucial to assess the different domains of ADHD symptoms precisely over the course of a day to determine the optimal titration and stimulant formulation for a person with ADHD...
Structural brain abnormalities in adolescents with autism spectrum disorder and patients with attention deficit/hyperactivity disorderSarah Brieber
Child Neuropsychology Section, Department of Child and Adolescent Psychiatry, University Hospital Aachen, Germany
J Child Psychol Psychiatry 48:1251-8. 2007..For the identification of endophenotypes across diagnostic categories, further investigations of phenotypic overlap between ADHD and autism at the behavioural, neurocognitive, and brain levels are needed...
Attentional dysfunction in children after corrective cardiac surgery in infancyHedwig H Hövels-Gürich
Department of Pediatric Cardiology, Aachen University of Technology, Aachen, Germany
Ann Thorac Surg 83:1425-30. 2007..Attentional dysfunction in children after corrective cardiac surgery in infancy has rarely been evaluated and is the topic of the present work...
Attentional functions in children and adolescents with ADHD, depressive disorders, and the comorbid conditionThomas Gunther
Child Neuropsychology Section, Department of Child and Adolescent Psychiatry, Medical Faculty, RWTH Aachen University, Germany
J Child Psychol Psychiatry 52:324-31. 2011..This study examines the influence of DDs on ADHD in a model-oriented approach that includes selectivity and intensity attention parameters...
Age-dependent differences in attentional processes in ADHD and disruptive behavior disorderThomas Gunther
Child Neuropsychology Section, Department of Child and Adolescent Psychiatry, University Clinics, Technical University Aachen, Aachen, Germany
Dev Neuropsychol 34:422-34. 2009..However, these group differences between ADHD, ADHD + DBD, and controls decreased with increasing age. Thus, age-related differences must be considered in neuropsychological studies...
Attentional performance in children and adolescents with tic disorder and co-occurring attention-deficit/hyperactivity disorder: new insights from a 2 × 2 factorial design studyEllen Greimel
Child Neuropsychology Section, Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital of RWTH Aachen, 52074, Aachen, Germany
J Abnorm Child Psychol 39:819-28. 2011....
The influence of risperidone on attentional functions in children and adolescents with attention-deficit/hyperactivity disorder and co-morbid disruptive behavior disorderThomas Gunther
Department of Child and Adolescent Psychiatry, Aachen University, Aachen, Germany
J Child Adolesc Psychopharmacol 16:725-35. 2006..However, no negative impact of risperidone was observed on attentional functions either, i.e., there was no slowing of cognitive speed...
The influence of sertraline on attention and verbal memory in children and adolescents with anxiety disordersThomas Gunther
Department of Child and Adolescent Psychiatry, Aachen University, Aachen, Germany
J Child Adolesc Psychopharmacol 15:608-18. 2005..Thus, the cognitive side effects of sertraline seemed to differ slightly between pediatric patients and those described in adult patient groups, should, therefore, be carefully assessed...
Neural mechanisms of encoding social and non-social context information in autism spectrum disorderEllen Greimel
Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital of the RWTH Aachen, Aachen, Germany
Neuropsychologia 50:3440-9. 2012..Increased activation in the dorsal MPFC in ASD individuals might reflect supervisory cognitive processes related to the suppression of a distracting non-social context...
The role of finger representations and saccades for number processing: an FMRI study in childrenHelga Krinzinger
Section Child Neuropsychology, Department of Child and Adolescent Psychiatry, University Hospital of the RWTH Aachen Aachen, Germany
Front Psychol 2:373. 2011..We conclude that finger counting may critically mediate the step from non-symbolic to symbolic and exact number processing via somatosensory integration processes and therefore represents an important example of embodied cognition...
Neural interaction of speech and gesture: differential activations of metaphoric co-verbal gesturesTilo Kircher
Department of Psychiatry and Psychotherapy, RWTH Aachen University, Pauwelsstr 30, D 52074 Aachen, Germany
Neuropsychologia 47:169-79. 2009..Speech related gestures seem to enhance language comprehension during the face-to-face communication...
Structural brain abnormalities in adolescent anorexia nervosa before and after weight recovery and associated hormonal changesVerena Mainz
Department of Child and Adolescent Psychiatry and Psychotherapy, University Hospital of the RWTH Aachen, Aachen, Germany
Psychosom Med 74:574-82. 2012..In particular, little is known about the changes in and the recovery of gray matter (GM) volumes after weight gain and the relation to hormonal normalization in adolescent patients with AN...
Association between neuroendocrinological parameters and learning and memory functions in adolescent anorexia nervosa before and after weight recoveryKatharina Buehren
University Hospital Aachen, Pauwelsstrase 30, 52074 Aachen, Germany
J Neural Transm 118:963-8. 2011..Normalization of body weight and resuming of menses is needed to restore learning and memory functions as well as to alleviate depressive symptoms...
Serotonergic neurotransmission and lapses of attention in children and adolescents with attention deficit hyperactivity disorder: availability of tryptophan influences attentional performanceFlorian D Zepf
Department of Child and Adolescent Psychiatry and Psychotherapy, RWTH University of Aachen, Germany
Int J Neuropsychopharmacol 13:933-41. 2010....
Sensitivity, reproducibility, and reliability of self-paced versus fixed stimulus presentation in an fMRI study on exact, non-symbolic arithmetic in typically developing children aged between 6 and 12 yearsHelga Krinzinger
Section Child Neuropsychology, Department of Child and Adolescent Psychiatry, University Hospital of the RWTH, Aachen, Germany
Dev Neuropsychol 36:721-40. 2011..Therefore, self-paced study designs seem to be a valid option for developmental fMRI studies on higher cognition...
[The effect of social and monetary reward on inhibitory control in boys with hyperkinetic conduct disorder]Timo D Vloet
Klinik fur Psychiatrie, Psychosomatik und Psychotherapie des Kindes und Jugendalters, Universitätsklinikum der RWTH Aachen
Z Kinder Jugendpsychiatr Psychother 39:341-9. 2011..This study investigated the effects of social and monetary reward on response inhibition in boys with ADHD + CD/ODD compared to healthy controls...
[Self-report and parental report of empathy in adolescents with autism]Ellen Greimel
Lehr und Forschungsgebiet Klinische Neuropsychologie des Kindes und Jugendalters, Klinik fur Psychiatrie, Psychosomatik und Psychotherapie des Kindes und Jugendalters, Universitätsklinikum der RWTH Aachen
Z Kinder Jugendpsychiatr Psychother 39:113-21. 2011..The present study assesses affective components of empathy via both self-report and parental report...
Neural mechanisms of interference control and time discrimination in attention-deficit/hyperactivity disorderTimo D Vloet
Cognitive Neurology Section, Institute of Neuroscience and Medicine, Research Centre Juelich, Aachen University, Germany
J Am Acad Child Adolesc Psychiatry 49:356-67. 2010..Both executive functions and time perception are typically impaired in subjects with attention-deficit/hyperactivity disorder (ADHD). However, the exact neural mechanisms underlying these deficits remain to be investigated...
[Neuroimaging data of ADHD, tic-disorder and obsessive-compulsive-disorder in children and adolescents]Timo D Vloet
Klinik fur Kinder und Jugendpsychiatrie und psychotherapie, Universitatsklinikum Aachen, Neuenhofer Weg 21, DE 52074 Aachen
Z Kinder Jugendpsychiatr Psychother 34:343-55. 2006..Since the majority of the studies reviewed are characterised by small and heterogeneous samples, and since the studies differ in their methods, comparability is limited and general conclusions can not be drawn...
Long-term neurodevelopmental outcome and exercise capacity after corrective surgery for tetralogy of Fallot or ventricular septal defect in infancyHedwig H Hövels-Gürich
Department of Pediatric Cardiology, Aachen University of Technology, Aachen, Germany
Ann Thorac Surg 81:958-66. 2006....
Anticipation of monetary and social reward differently activates mesolimbic brain structures in men and womenKatja N Spreckelmeyer
Department of Psychiatry and Psychotherapy, RWTH Aachen University, Germany
Soc Cogn Affect Neurosci 4:158-65. 2009..Our findings represent an important step towards a better understanding of motivated behaviour by taking into account individual differences in reward valuation...
[Neuropsychological performance in anorexia and bulimia nervosa]Katharina Bühren
Klinik fur Kinder und Jugendpsychiatrie und psychotherapie, Universitatsklinikum Aachen
Z Kinder Jugendpsychiatr Psychother 36:377-86; quiz 387-8. 2008..The following review describes in detail the neuropsychological impairments in eating disorders, potential factors influencing cognitive performance, and resulting implications for clinical every day life...
Aetiology of anorexia nervosa: from a "psychosomatic family model" to a neuropsychiatric disorder?Beate Herpertz-Dahlmann
Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, RWTH Aachen University, Neuenhofer Weg 21, 52074 Aachen, Germany
Eur Arch Psychiatry Clin Neurosci 261:S177-81. 2011....
Early pathogenic care and the development of ADHD-like symptomsBrigitte Dahmen
Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Medical Faculty, RWTH Aachen University, Neuenhofer Weg 21, 52074 Aachen, Germany
J Neural Transm 119:1023-36. 2012..Based on this evidence, suggestions for the treatment of ADHD-like symptoms in children after adverse early life experiences are provided...
Hyperresponsiveness to social rewards in children and adolescents with attention-deficit/hyperactivity disorder (ADHD)Gregor Kohls
Child Neuropsychology Section, Department of Child and Adolescent Psychiatry and Psychotherapy, RWTH Aachen University, Neuenhofer Weg 21, D 52074 Aachen, Germany
Behav Brain Funct 5:20. 2009..abstract:..
Acquired dyslexia after stroke in the prereading stage: a single case treatment study with f MRIAnja Fiori
Department of Neurolinguistics, University Hospital of Aachen, Aachen, Germany
Neurocase 12:252-62. 2006..Data showed significant gains in reading performance only after the specific intervention. These gains remained stable in a catamnesis 2 years later...
Differential effects of social and non-social reward on response inhibition in children and adolescentsGregor Kohls
Child Neuropsychology Section, Department of Child and Adolescent Psychiatry and Psychotherapy, RWTH Aachen University, Aachen, Germany
Dev Sci 12:614-25. 2009..Clinical implications regarding probable hyposensitivity to social reward in subjects with autism and dysregulated reward-seeking behaviour in children with attention-deficit/hyperactivity disorder (ADHD) are discussed...
Catecholamine functioning in children with traumatic brain injuries and children with attention-deficit/hyperactivity disorderKerstin Konrad
Department of Child and Adolescent Psychiatry, RWTH Aachen, Neuenhofer Weg 21, D 52074 Aachen, Germany
Brain Res Cogn Brain Res 16:425-33. 2003..Our study provides further support for similar but also different neurobiochemical characteristics in both groups...
Structural and functional MRI- findings in children and adolescents with antisocial behaviorTimo D Vloet
Department of Child and Adolescent Psychiatry and Psychotherapy, RWTH Aachen, University Hospital, Neuenhofer Weg 21, D 52074 Aachen, Germany
Behav Sci Law 26:99-111. 2008..Though the investigation of biological factors in antisocial subjects has made great progress in recent years, today MRI is still a rather complex, expensive and indistinct method for forensic assessment...
[Reliability of attention and verbal memory tests with normal children and adolescents--clinical implications]Thomas Gunther
Klinik fur Kinder und Jugendpsychiatrie und psychotherapie, Universitatsklinikum Aachen
Z Kinder Jugendpsychiatr Psychother 33:169-79. 2005..Selected clinical findings are summarised. Neuropsychological attention and memory tasks that are suited for the examination of children and adolescents are described...
Neurophysiological correlates of relatively enhanced local visual search in autistic adolescentsZina M Manjaly
Institute of Neuroscience and Biophysics, Department of Medicine, Research Centre Julich, 52425 Julich, Germany
Neuroimage 35:283-91. 2007..These results suggest that enhanced local processing in early visual areas, as opposed to impaired processing of global context, is characteristic for performance of the EFT by autistic patients...
Emotional processing in male adolescents with childhood-onset conduct disorderSabine C Herpertz
Department of Psychiatry and Psychotherapy, University of Rostock, Germany
J Child Psychol Psychiatry 49:781-91. 2008..While a number of functional neuroimaging studies on emotional processing have been performed in antisocial adults, little is known about how CD children process emotional information...
