B Koletzko

Summary

Affiliation: University of Munich
Country: Germany

Publications

  1. doi Omega-3 LC-PUFA supply and neurological outcomes in children with phenylketonuria (PKU)
    Berthold Koletzko
    Division of Metabolic Diseases and Nutritional Medicine, Dr von Hauner Children s Hospital, University of Munich Medical Centre, Munich, Germany
    J Pediatr Gastroenterol Nutr 48:S2-7. 2009
  2. doi Does dietary DHA improve neural function in children? Observations in phenylketonuria
    Berthold Koletzko
    Division of Metabolic Diseases and Nutritional Medicine, Dr von Hauner Children s Hospital, University of Munich Medical Centre, Lindwurmstr 4, 80337 Munich, Germany
    Prostaglandins Leukot Essent Fatty Acids 81:159-64. 2009
  3. doi Dietary intake of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in children - a workshop report
    Berthold Koletzko
    Division of Metabolic Diseases and Nutrition, Dr von Hauner Children s Hospital, University of Munich Medical Centre, Munich, Germany
    Br J Nutr 103:923-8. 2010
  4. doi Genetic variants of the fatty acid desaturase gene cluster predict amounts of red blood cell docosahexaenoic and other polyunsaturated fatty acids in pregnant women: findings from the Avon Longitudinal Study of Parents and Children
    Berthold Koletzko
    Department of Pediatrics, Dr von Hauner Children s Hospital, University of Munich Medical Center, Munich, Germany
    Am J Clin Nutr 93:211-9. 2011
  5. pmc Efficient and specific analysis of red blood cell glycerophospholipid fatty acid composition
    Sabrina Klem
    Division of Metabolic and Nutritional Medicine, Dr von Hauner Children s Hospital, University of Munich Medical Center, Munich, Germany
    PLoS ONE 7:e33874. 2012
  6. pmc High-throughput analysis of total plasma fatty acid composition with direct in situ transesterification
    Claudia Glaser
    Division of Metabolic and Nutritional Medicine, Dr von Hauner Children s Hospital, University of Munich Medical Center, Munich, Germany
    PLoS ONE 5:e12045. 2010
  7. pmc Influence of FADS polymorphisms on tracking of serum glycerophospholipid fatty acid concentrations and percentage composition in children
    Claudia Glaser
    Division of Metabolic and Nutritional Medicine, Dr von Hauner Children s Hospital, University of Munich Medical Center, Munich, Germany
    PLoS ONE 6:e21933. 2011
  8. pmc Folate catabolites in spot urine as non-invasive biomarkers of folate status during habitual intake and folic acid supplementation
    Mareile Niesser
    Division of Metabolic and Nutritional Medicine, Dr von Hauner Children s Hospital Medical Center of Ludwig Maximilians University, Munich, Germany
    PLoS ONE 8:e56194. 2013
  9. doi Compositional requirements of follow-up formula for use in infancy: recommendations of an international expert group coordinated by the Early Nutrition Academy
    Berthold Koletzko
    Dr von Hauner Children s Hospital, University of Munich, Munich, Germany
    Ann Nutr Metab 62:44-54. 2013
  10. doi Documentation of functional and clinical effects of infant nutrition: setting the scene for COMMENT
    Berthold Koletzko
    Dr von Hauner Children s Hospital, University of Munich Medical Centre, Germany
    Ann Nutr Metab 60:222-32. 2012

Detail Information

Publications89

  1. doi Omega-3 LC-PUFA supply and neurological outcomes in children with phenylketonuria (PKU)
    Berthold Koletzko
    Division of Metabolic Diseases and Nutritional Medicine, Dr von Hauner Children s Hospital, University of Munich Medical Centre, Munich, Germany
    J Pediatr Gastroenterol Nutr 48:S2-7. 2009
    ..Further studies are ongoing aiming at establishing quantitative DHA requirements in children...
  2. doi Does dietary DHA improve neural function in children? Observations in phenylketonuria
    Berthold Koletzko
    Division of Metabolic Diseases and Nutritional Medicine, Dr von Hauner Children s Hospital, University of Munich Medical Centre, Lindwurmstr 4, 80337 Munich, Germany
    Prostaglandins Leukot Essent Fatty Acids 81:159-64. 2009
    ..Since PKU children are generally healthy and have normal energy and fatty acid metabolism, these data lead us to conclude that childhood populations in general require preformed n-3 LC-PUFA to achieve optimal neurological function...
  3. doi Dietary intake of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in children - a workshop report
    Berthold Koletzko
    Division of Metabolic Diseases and Nutrition, Dr von Hauner Children s Hospital, University of Munich Medical Centre, Munich, Germany
    Br J Nutr 103:923-8. 2010
    ..Adequately designed studies addressing dietary intakes, measures of status and relevant functional or health effects across this age group are needed...
  4. doi Genetic variants of the fatty acid desaturase gene cluster predict amounts of red blood cell docosahexaenoic and other polyunsaturated fatty acids in pregnant women: findings from the Avon Longitudinal Study of Parents and Children
    Berthold Koletzko
    Department of Pediatrics, Dr von Hauner Children s Hospital, University of Munich Medical Center, Munich, Germany
    Am J Clin Nutr 93:211-9. 2011
    ..Associations with docosahexaenoic acid (DHA), which is considered particularly important for brain and retina development, are hardly existent...
  5. pmc Efficient and specific analysis of red blood cell glycerophospholipid fatty acid composition
    Sabrina Klem
    Division of Metabolic and Nutritional Medicine, Dr von Hauner Children s Hospital, University of Munich Medical Center, Munich, Germany
    PLoS ONE 7:e33874. 2012
    ..The analysis of these lipid fractions is demanding and time consuming and total phospholipid n-3 fatty acid levels might be affected by changes of sphingomyelin contents in the RBC membrane during n-3 supplementation...
  6. pmc High-throughput analysis of total plasma fatty acid composition with direct in situ transesterification
    Claudia Glaser
    Division of Metabolic and Nutritional Medicine, Dr von Hauner Children s Hospital, University of Munich Medical Center, Munich, Germany
    PLoS ONE 5:e12045. 2010
    ..The total plasma FA pool represents the composition of all FA containing lipid fractions. We developed a simplified and affordable high-throughput method for the analysis of total plasma FA composition, suitable for large studies...
  7. pmc Influence of FADS polymorphisms on tracking of serum glycerophospholipid fatty acid concentrations and percentage composition in children
    Claudia Glaser
    Division of Metabolic and Nutritional Medicine, Dr von Hauner Children s Hospital, University of Munich Medical Center, Munich, Germany
    PLoS ONE 6:e21933. 2011
    ..Tracking of fatty acid (FA) contribution to plasma or serum lipids over time was shown in children and adults. However, the potential role of FADS gene variants has not been investigated...
  8. pmc Folate catabolites in spot urine as non-invasive biomarkers of folate status during habitual intake and folic acid supplementation
    Mareile Niesser
    Division of Metabolic and Nutritional Medicine, Dr von Hauner Children s Hospital Medical Center of Ludwig Maximilians University, Munich, Germany
    PLoS ONE 8:e56194. 2013
    ..Folate degradation products para-aminobenzoylglutamate (pABG) and para-acetamidobenzoylglutamate (apABG) in 24 hour urine have recently been shown to correlate with blood folate...
  9. doi Compositional requirements of follow-up formula for use in infancy: recommendations of an international expert group coordinated by the Early Nutrition Academy
    Berthold Koletzko
    Dr von Hauner Children s Hospital, University of Munich, Munich, Germany
    Ann Nutr Metab 62:44-54. 2013
    ..This has not been considered as part of this review and should be the subject of further consideration...
  10. doi Documentation of functional and clinical effects of infant nutrition: setting the scene for COMMENT
    Berthold Koletzko
    Dr von Hauner Children s Hospital, University of Munich Medical Centre, Germany
    Ann Nutr Metab 60:222-32. 2012
    ..The COMMENT Steering Committee will discuss and decide upon a method for reaching consensus which will be used by all working groups and plan to meet again within 2 years and to report and publish their conclusions...
  11. doi Quality and safety aspects of infant nutrition
    Berthold Koletzko
    Dr von Hauner Children s Hospital, University of Munich Medical Centre, Lindwurmstrasse 4, Munich, Germany
    Ann Nutr Metab 60:179-84. 2012
    ..Global collaboration of food producers, food-safety authorities, paediatricians and scientists is needed to efficiently exchange information and to best protect public health...
  12. doi Physiological aspects of human milk lipids and implications for infant feeding: a workshop report
    Berthold Koletzko
    Division of Metabolic and Nutritional Medicine, Dr von Hauner Children s Hospital, University of Munich Medical Center, Germany
    Acta Paediatr 100:1405-15. 2011
    ..The compositional and biological effects of human milk lipids have received considerable interest regarding their modulating effects on growth, metabolism and functions of the cardiovascular, immune and nervous system...
  13. doi The Early Nutrition Programming Project (EARNEST): 5 y of successful multidisciplinary collaborative research
    Berthold Koletzko
    Division of Metabolic and Nutritional Medicine, Dr von Hauner Children s Hospital, University of Munich Medical Center, Munich, Germany
    Am J Clin Nutr 94:1749S-1753S. 2011
    ..This article highlights some of the scientific results, achievements, and efforts of EARNEST...
  14. doi Infant feeding and later obesity risk
    Berthold Koletzko
    Dr von Hauner Children s Hospital, Ludwig Maximilians University of Munich, Germany
    Adv Exp Med Biol 646:15-29. 2009
    ..These results demonstrate that modification of infant feeding practice has an important potential for long-term health promotion and should prompt a review of the recommendations and policies for infant formula composition...
  15. doi Programming research: where are we and where do we go from here?
    Berthold Koletzko
    Division of Metabolic and Nutritional Medicine, Department of Pediatrics, Dr von Hauner Children s Hospital, University of Munich Medical Center, Munich, Germany
    Am J Clin Nutr 94:2036S-2043S. 2011
    ..The scientific know-how and methodology available today allow us to take major steps forward in the near future; hence, research on nutritional programming deserves high priority...
  16. doi Lower protein in infant formula is associated with lower weight up to age 2 y: a randomized clinical trial
    Berthold Koletzko
    Dr von Hauner Children s Hospital, University of Munich Medical Centre, Munich, Germany
    Am J Clin Nutr 89:1836-45. 2009
    ..Protein intake during infancy was associated with rapid early weight gain and later obesity in observational studies...
  17. ncbi [Infant feeding practice and later obesity risk. Indications for early metabolic programming]
    B Koletzko
    Abt Stoffwechsel und Ernährungsmedizin, Dr von Haunersches Kinderspital, Klinikum der Ludwig Maximilians Universität München, Lindwurmstr 4, 80337, Munchen, Deutschland
    Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 53:666-73. 2010
    ..We conclude that infant feeding practice has a high potential for long-term health effects. The results obtained should stimulate the review of recommendations and policies for infant formula composition...
  18. doi Fish oil containing intravenous lipid emulsions in parenteral nutrition-associated cholestatic liver disease
    Berthold Koletzko
    Division of Metabolic and Nutritional Medicine, Dr von Hauner Children s Hospital, University of Munich Medical Center, Munich, Germany
    Curr Opin Clin Nutr Metab Care 13:321-6. 2010
    ..Here, we summarize current data...
  19. doi Meal patterns and frequencies: do they affect body weight in children and adolescents?
    Berthold Koletzko
    Dr von Hauner Children s Hospital, University of Munich Medical Centre, Germany
    Crit Rev Food Sci Nutr 50:100-5. 2010
    ....
  20. ncbi Influence of formulas with borage oil or borage oil plus fish oil on the arachidonic acid status in premature infants
    H Demmelmair
    Kinderklinik and Kinderpoliklinik, Dr. von Haunersches Kinderspital, Ludwig-Maximilians University, Munich, Germany
    Lipids 36:555-66. 2001
    ..The effect of GLA on AA is independent of the EPA and DHA content in the diet within the dose ranges studied...
  21. doi Can infant feeding choices modulate later obesity risk?
    Berthold Koletzko
    Dr von Hauner Children s Hospital, Ludwig Maximilians University, Munich, Germany
    Am J Clin Nutr 89:1502S-1508S. 2009
    ..We conclude that infant feeding practice has a high potential for long-term health effects, and the results obtained should stimulate the review of recommendations and policies for infant formula composition...
  22. doi Dietary intake of natural sources of docosahexaenoic acid and folate in pregnant women of three European cohorts
    C Franke
    Division of Metabolism and Nutrition, Dr von Hauner Children s Hospital, Munich, Germany
    Ann Nutr Metab 53:167-74. 2008
    ..Docosahexaenoic acid (DHA) has been associated with infantile neurological and cognitive development. Thus, optimal intrauterine development and growth requires adequate supply of these nutrients during pregnancy...
  23. ncbi Dietary long-chain polyunsaturated fatty acid supplementation in infants with phenylketonuria: a randomized controlled trial
    B Koletzko
    Department of Paediatrics, University of Munich, Munich, Germany
    J Inherit Metab Dis 30:326-32. 2007
    ..Children with phenylketonuria (PKU) consume diets with very low contents of preformed LCPUFA. We studied prospectively the LCPUFA status in infants with PKU without or with LCPUFA supplementation during the first year of life...
  24. ncbi Physiological aspects of human milk lipids
    B Koletzko
    Department of Pediatrics, Kinderklinik and Kinderpoliklinik, Dr von Haunersches Kinderspitel, Ludwig Maximilians University of Munich, Lindwurmstr 4, D 80337, Munich, Germany
    Early Hum Dev 65:S3-S18. 2001
    ..Thus, not only the woman's current but also her long-term dietary intake is of marked relevance for milk fat composition...
  25. ncbi Metabolic effects of intravenous LCT or MCT/LCT lipid emulsions in preterm infants
    Frauke Lehner
    Dr von Hauner Children s Hospital, Ludwig Maximilians University, Munich, Germany
    J Lipid Res 47:404-11. 2006
    ..Both lipid emulsions achieve similar plasma essential fatty acid (EFA) contents and similar proportional conversion of EFAs to LC-PUFAs. The MCT/LCT emulsion seems to protect EFAs and LC-PUFAs from beta-oxidation...
  26. doi FADS gene variants modulate the effect of dietary fatty acid intake on allergic diseases in children
    M Standl
    Institute of Epidemiology I, Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Munich, Germany
    Clin Exp Allergy 41:1757-66. 2011
    ..The association between dietary fatty acid intake and the development of atopic diseases has been inconsistent. This could be due to inter-individual genetic differences in fatty acid metabolism...
  27. ncbi Reduced risk for overweight and obesity in 5- and 6-y-old children by duration of sleep--a cross-sectional study
    R von Kries
    Institute for Social Paediatrics and Adolescent Medicine, Ludwig Maximilians University of Munich, Munich, Germany
    Int J Obes Relat Metab Disord 26:710-6. 2002
    ..To assess the relationship between sleep duration and adiposity in 5- and 6-y-old Bavarian children...
  28. ncbi Nutritional and biochemical properties of human milk, Part I: General aspects, proteins, and carbohydrates
    C Kunz
    Department of Pediatrics, Kinderklinik, Ludwig Maximilians University of Munich, Germany
    Clin Perinatol 26:307-33. 1999
    ....
  29. ncbi Fatty acid profiles, antioxidant status, and growth of preterm infants fed diets without or with long-chain polyunsaturated fatty acids. A randomized clinical trial
    Berthold Koletzko
    Dr von Hauner Children s Hospital, Ludwig Maximilians University of Munich, Lindwurmstr 4, 80337, Munchen, Germany de
    Eur J Nutr 42:243-53. 2003
    ..Our results demonstrate that plasma LCP levels similar to those of breast fed infants can be achieved with the LCP supplemented formula used in this trial, without evidence of adverse effects of the LCP enrichment...
  30. ncbi Overweight and obesity in 6- to 14-year-old Czech children in 1991: protective effect of breast-feeding
    Andre Michael Toschke
    Ludwig Maximilians University, Institute of Social Pediatrics and Adolescent Medicine, Munich, Germany
    J Pediatr 141:764-9. 2002
    ..To assess the impact of breast-feeding on childhood overweight/obesity in an Eastern European socialist society with relatively homogeneous lifestyles...
  31. ncbi The effect of docosahexaenoic acid and folic acid supplementation on placental apoptosis and proliferation
    Mario Klingler
    Dr von Hauner Children s Hospital, Ludwig Maximilians University of Munich, Munich, Germany
    Br J Nutr 96:182-90. 2006
    ..A defined combination of DHA and 5-MTHF may, however, affect placental proliferation...
  32. doi Obesity related programming statements in materials on infant feeding aimed at parents in five European countries
    Julia von Rosen-von Hoewel
    Dr von Hauner Children s Hospital, Ludwig Maximilians University, Munich, Germany
    Adv Exp Med Biol 646:175-81. 2009
    ..This is important as obesity and its resulting morbidity are of increasing public health concern in developed countries...
  33. ncbi The use of stable isotope techniques for nutritional and metabolic research in paediatrics
    B Koletzko
    Kinderklinik nd Kinderpoliklinik, Klinikum Innenstadt, Ludwig Maximilians University of Munich, Germany
    Early Hum Dev 53:S77-97. 1998
    ..These few examples of recent developments demonstrate the great clinical and scientific potential of stable isotope methods in future paediatric applications...
  34. pmc Access technique and its problems in parenteral nutrition - Guidelines on Parenteral Nutrition, Chapter 9
    K W Jauch
    Dept Surgery Grosshadern, University Hospital, Munich, Germany
    Ger Med Sci 7:Doc19. 2009
    ..A peripheral venous catheter (PVC) can remain in situ for as long as it is clinically required unless there are signs of inflammation at the insertion site...
  35. ncbi Polyunsaturated fatty acids in human milk and their role in early infant development
    B Koletzko
    Division Metabolic Diseases and Nutrition Kinderklinik and Kinderpoliklinik, Dr von Haunersches Kinderspital, Ludwigs Maximilians University of Munich, Munchen, Germany
    J Mammary Gland Biol Neoplasia 4:269-84. 1999
    ..Here we discuss the PUFA composition of human milk, factors which determine and modulate milk PUFA content, and possible effects of milk LC-PUFA on infant growth and development...
  36. ncbi Polyunsaturated fatty acid supply with human milk
    T U Sauerwald
    Kinderklinik and Kinderpoliklinik, Dr von Haunersches Kinderspital, Ludwig Maximilians University, Munich, Germany
    Lipids 36:991-6. 2001
    ..Based on these studies, the major part of polyunsaturated fatty acids in human milk seems not to be provided directly from the diet but from maternal tissue stores...
  37. pmc Introduction and methodology - Guidelines on Parenteral Nutrition, Chapter 1
    B Koletzko
    Dept Metabolic Diseases and Nutritional Medicine, Dr von Hauner Children s Hospital, University of Munich, Germany
    Ger Med Sci 7:Doc26. 2009
    ..The recommendations of the guidelines should be reviewed, and if necessary updated five years after publication...
  38. ncbi Role of FADS1 and FADS2 polymorphisms in polyunsaturated fatty acid metabolism
    Claudia Glaser
    Division of Metabolic Diseases and Nutritional Medicine, Dr von Hauner Children s Hospital, Ludwig Maximilians University of Munich, Munich, Germany
    Metabolism 59:993-9. 2010
    ..We recommend including analyses of FADS1 and FADS2 polymorphism in future cohort and intervention studies addressing biological effects of PUFAs and LC-PUFAs...
  39. ncbi Long chain polyunsaturated fatty acids (LC-PUFA) and perinatal development
    B Koletzko
    Dr von Haunersches Kinderspital, Ludwig Maximilians University of Munich, Germany
    Acta Paediatr 90:460-4. 2001
    ..However, it seems prudent for pregnant and lactating women to include some food sources of DHA in their diet in view of their assumed increase in LC-PUFA demand and the relationship between maternal and foetal DHA status...
  40. pmc Complications and monitoring - Guidelines on Parenteral Nutrition, Chapter 11
    W H Hartl
    Dept Surgery Grosshadern, University Hospital, Munich, Germany
    Ger Med Sci 7:Doc17. 2009
    ..Monitoring metabolic determinants of bone metabolism is particularly important in patients receiving long-term PN. Markers of intermediary, electrolyte and trace element metabolism require regular checks...
  41. ncbi Fish oil supplementation improves visual evoked potentials in children with phenylketonuria
    S Beblo
    Division of Metabolic Diseases and Nutrition, Dr. von Haunersches Kinderspital, Munich, Germany
    Neurology 57:1488-91. 2001
    ..The authors conclude that omega-3 LC-PUFA are essential substrates for nervous system function even beyond infancy...
  42. ncbi Regulation of ghrelin is related to estimated insulin sensitivity in obese children
    K Krohn
    Division of Metabolic Diseases and Nutritional Medicine, Dr von Hauner Children s Hospital, University of Munich, Germany
    Int J Obes (Lond) 30:1482-7. 2006
    ..To investigate whether ghrelin concentrations and their changes during weight loss in obese children are associated with parameters of glucose and insulin metabolism...
  43. ncbi [Hyperlipidemia in children and adolescents: diagnosis and therapy]
    B Koletzko
    Kinderpoliklinik, Klinikum Innenstadt der Ludwig Maximilians Universität München
    Schweiz Med Wochenschr 128:477-85. 1998
    ..g. bezafibrate, fenofibrate) may be considered as a drug of second choice. Cholesterol synthesis inhibitors are not recommended for general use in children at this time...
  44. pmc Maternal postnatal depression and child growth: a European cohort study
    Veit Grote
    Dr von Hauner Children s Hospital, Ludwig Maximilians University of Munich, Munich, Germany
    BMC Pediatr 10:14. 2010
    ..This study examined the hypothesis that maternal postnatal depression may be a risk factor for later child growth faltering or overweight...
  45. doi Allergen avoidance approaches in food allergy management
    Sibylle Koletzko
    Division of Paediatric Gastroenterology and Hepatology, Dr von Hauner Children s Hospital, University of Munich Medical Center, Munich, Germany
    Nestle Nutr Workshop Ser Pediatr Program 64:169-80; discussion 180-4, 251-7. 2009
    ..Elimination diets must be supervised and monitored to a similar degree as drug treatments, and the need for continued dietary elimination should be reviewed on a regular basis and re-challenges considered...
  46. doi Infant formula supplementation with long-chain polyunsaturated fatty acids has no effect on Bayley developmental scores at 18 months of age--IPD meta-analysis of 4 large clinical trials
    Andreas Beyerlein
    Division of Epidemiology, Institute of Social Paediatrics and Adolescent Medicine, Ludwig Maximilians University of Munich, Munich, Germany
    J Pediatr Gastroenterol Nutr 50:79-84. 2010
    ..To find out whether supplementation of formula milk by long-chain polyunsaturated fatty acids (LCPUFA) affects neurodevelopment at 18 months of age in term or preterm infants by an individual patient data (IPD) meta-analysis...
  47. doi IPD meta-analysis shows no effect of LC-PUFA supplementation on infant growth at 18 months
    Eva Rosenfeld
    Institute for Social Pediatrics and Adolescent Medicine, University of Munich, Heiglhofstrasse 63, Munich, Germany
    Acta Paediatr 98:91-7. 2009
    ..We examined the effects of LC-PUFAs-- especially docosahexaenoic acid (DHA) and arachidonic acid (AA)--on growth at 18 months...
  48. ncbi Identifying children at high risk for overweight at school entry by weight gain during the first 2 years
    Andre Michael Toschke
    Institute of Social Pediatrics and Adolescent Medicine, Division of Epidemiology, Ludwig Maximilians University, Munich, Germany
    Arch Pediatr Adolesc Med 158:449-52. 2004
    ..To assess the best anthropometric predictor from birth to 2 years for later overweight, based on recent studies reporting that large infant weight or length gain predicts subsequent overweight...
  49. ncbi Long-term consequences of early nutrition
    Hans Demmelmair
    Division of Metabolic Diseases and Nutrition, Dr von Hauner Children s Hospital, Ludwig Maximilians University of Munich, Lindwurmstrasse 4, D 80337 Munich, Germany
    Early Hum Dev 82:567-74. 2006
    ..metabolic-programming.org) should provide further insights into metabolic programming and help to transfer scientific progress into clinical practice...
  50. ncbi Effect of early enteral feeding on apolipoprotein AI levels and high-density lipoprotein heterogeneity in preterm infants
    Orsolya Genzel-Boroviczeny
    Department of Neonatology, Klinikum Grosshadern, Ludwig Maximilians University, Munich, Germany
    Ann Nutr Metab 46:121-7. 2002
    ..This study investigates the influence of early enteral feedings on apolipoprotein AI and HDL subclasses...
  51. ncbi Global standard for the composition of infant formula: recommendations of an ESPGHAN coordinated international expert group
    Berthold Koletzko
    Dr von Hauner Children s Hospital, University of Munich, Germany
    J Pediatr Gastroenterol Nutr 41:584-99. 2005
    ..The group arrived at recommendations on the compositional requirements for a global infant formula standard which are reported here...
  52. ncbi Placental transfer of long-chain polyunsaturated fatty acids (LC-PUFA)
    Berthold Koletzko
    Department of Pediatrics, Dr von Hauner Children s Hospital, Ludwig Maximilians University of Munich, Munich, Germany
    J Perinat Med 35:S5-11. 2007
    ..Such studies should contribute to optimize substrate intake during pregnancy and lactation that may improve pregnancy outcome as well as fetal growth and development...
  53. ncbi Maternal smoking during pregnancy and childhood obesity
    Rudiger Von Kries
    Institute of Social Pediatrics and Adolescent Medicine, Ludwig Maximilian University of Munich, Munich, Germany
    Am J Epidemiol 156:954-61. 2002
    ....
  54. ncbi Effect of fish oil supplementation on fatty acid status, coordination, and fine motor skills in children with phenylketonuria
    Skadi Beblo
    Division of Metabolic Diseases and Nutrition, Dr von Haunersches Kinderspital, Ludwig Maximilians University, Munich, Germany
    J Pediatr 150:479-84. 2007
    ..To investigate effects of long-chain omega-3 polyunsaturated fatty acids (LC-PUFA) on motor skills in patients with phenylketonuria (PKU)...
  55. ncbi Characterisation of infant food modifications in the European Union
    Berthold Koletzko
    Division of Metabolic Disease and Nutritional Medicine, Dr von Hauner Children s Hospital, Ludwig Maximilian University of Munich, Germany
    Ann Nutr Metab 46:231-42. 2002
    ....
  56. ncbi Co-supplementation of healthy women with fish oil and evening primrose oil increases plasma docosahexaenoic acid, gamma-linolenic acid and dihomo-gamma-linolenic acid levels without reducing arachidonic acid concentrations
    Julia Geppert
    Division of Metabolic Diseases and Nutrition, Dr von Hauner Children s Hospital, Ludwig Maximilians University of Munich, Germany
    Br J Nutr 99:360-9. 2008
    ..It increases plasma GLA, DGLA, and DHA levels without impairing ARA status. These data provide a basis for testing this FSO/EPO blend in pregnant women for its effects on maternal and neonatal FA status and infant development...
  57. ncbi Dietary fat intakes for pregnant and lactating women
    Berthold Koletzko
    Dr von Hauner Children s Hospital, University of Munich, Germany
    Br J Nutr 98:873-7. 2007
    ....
  58. ncbi Prevalence of malnutrition in paediatric hospital patients
    Ingrid Pawellek
    Dr von Hauner Children s Hospital, University of Munich, Lindwurmstrasse 4, D 80337 München, Germany
    Clin Nutr 27:72-6. 2008
    ..We determined the prevalence of malnutrition in a series of unselected patients consecutively admitted as inpatients to a large tertiary care children's hospital in Germany...
  59. doi The roles of long-chain polyunsaturated fatty acids in pregnancy, lactation and infancy: review of current knowledge and consensus recommendations
    Berthold Koletzko
    Department of Pediatrics, University of Munich, Munchen, Germany
    J Perinat Med 36:5-14. 2008
    ..Dietary LC-PUFA supply should continue after the first six months of life, but currently there is not sufficient information for quantitative recommendations...
  60. ncbi Parenteral nutrition with standard solutions in paediatric intensive care patients
    Kathrin Krohn
    Division of Metabolic Diseaseas and Nutritional Medicine, Dr von Hauner Children s Hospital, University of Munich, Lindwurmstr, 4, D 80337 München, Germany
    Clin Nutr 24:274-80. 2005
    ..Since manual compounding is associated with a greater risk of compounding errors and microbial contamination, the use of standard solutions might be a preferable alternative...
  61. ncbi Report on the guidelines on parenteral nutrition in infants, children and adolescents
    Berthold Koletzko
    Division of Metabolic Diseases and Nutritional Medicine, Dr von Hauner Children s Hospital, Ludwig Maximilians University of Munich, Germany
    Clin Nutr 24:1105-9. 2005
  62. ncbi Analysis of FA contents in individual lipid fractions from human placental tissue
    M Klingler
    Division of Metabolism and Nutrition, Kinderklinik and Kinderpoliklinik, Dr von Hauner Children s Hospital, Ludwig Maximilians University of Munich, D 80337, Munich, Germany
    Lipids 38:561-6. 2003
    ..5-9.9%), whereas the absolute FA concentrations were only reproducible in the PL fraction (CV 7.0-12.8%). The method shows a reasonably high precision that is well suited for physiological and nutritional studies...
  63. ncbi Long-chain polyunsaturated fatty acids and eicosanoids in infants--physiological and pathophysiological aspects and open questions
    A Sellmayer
    Institut für Prophylaxe und Epidemiologie der Kreislaufkrankheiten und Medizinische Klinik, University of Munich, Germany
    Lipids 34:199-205. 1999
    ....
  64. ncbi Lipid supply for infants with special needs
    B Koletzko
    Kinderpoliklinik, University of Munich, Germany
    Eur J Med Res 2:69-73. 1997
    ..Further research is required to study in more detail the metabolic effects, functional outcomes and safety of different forms of LC-PUFA supply for infants...
  65. doi Mc2 receptor knockdown modulates differentiation and lipid composition in adipocytes
    M J Betz
    Endocrine Research Unit, Medizinische Klinik und Poliklinik IV, Munich, Germany
    Horm Metab Res 44:670-5. 2012
    ..MC2R plays an important role for regular lipolytic function and lipid composition in 3T3-L1 adipocytes. Of interest, desaturase expression was reduced and MUFA content accordingly altered in kd cells...
  66. ncbi Long-chain polyunsaturated fatty acids in diets for infants: choices for recommending and regulating bodies and for manufacturers of dietary products
    B Koletzko
    Department of Paediatrics, Ludwig Maximilians University of Munich, Germany
    Lipids 34:215-20. 1999
    ....
  67. ncbi Microalgal docosahexaenoic acid decreases plasma triacylglycerol in normolipidaemic vegetarians: a randomised trial
    Julia Geppert
    Division of Metabolic Diseases and Nutrition, Dr von Hauner Children s Hospital, Ludwig Maximilians University of Munich, Lindwurmstrasse 4, D 80337 Munich, Germany
    Br J Nutr 95:779-86. 2006
    ..Although DHA supplementation improved some CHD risk factors (plasma TG, TG:HDL cholesterol ratio), LDL cholesterol increased. Therefore, the overall effects of this intervention on CHD risk deserve further investigation...
  68. ncbi Paternal smoking is associated with a decreased prevalence of type 1 diabetes mellitus among offspring in two national British birth cohort studies (NCDS and BCS70)
    Audré M Toschke
    Division of Pediatric Epidemiology at the Institute of Social Pediatrics and Adolescent Medicine, and Dr von Hauner Children s Hospital, Ludwig Maximilians University Munich, Munich, Germany
    J Perinat Med 35:43-7. 2007
    ..This paper aims to assess the association of markers for prenatal exposures with IDDM...
  69. pmc Effect of elective abdominal surgery on human colon protein synthesis in situ
    P Rittler
    Department of Surgery, Klinikum Grosshadern, Munich, Germany
    Ann Surg 233:39-44. 2001
    ..The postoperative rate of colon protein synthesis is, compared with other tissues, among the highest measured thus far in humans...
  70. doi German national consensus recommendations on nutrition and lifestyle in pregnancy by the 'Healthy Start - Young Family Network'
    B Koletzko
    Dr von Hauner Children s Hospital, University of Munich Medical Center, Munich, Germany
    Ann Nutr Metab 63:311-22. 2013
    ..Pregnant women should not smoke and not stay in rooms where others smoke or have smoked before (passive smoking). Alcohol consumption should be avoided, since alcohol can harm unborn children...
  71. doi Use of electronic data capture in a clinical trial on infant feeding
    I Pawellek
    Department of Metabolic Diseases and Nutrition, Dr von Hauner Children s Hospital, University of Munich Medical Centre, Munich, Germany
    Eur J Clin Nutr 66:1342-3. 2012
    ..We use electronic data capture (EDC) in this trial and report here on our experience with the method...
  72. ncbi Lipid supply and metabolism in infancy
    B Koletzko
    Kinderpoliklinik, Ludwig Maximilians University of Munich, Germany
    Curr Opin Clin Nutr Metab Care 1:171-7. 1998
    ..Intravenous lipid emulsions are an indispensable part of parenteral nutrition of young children, and efforts are being made to improve the parenteral feeding regimens to meet the metabolic needs for this sensitive group of patients...
  73. ncbi Growth, development and differentiation: a functional food science approach
    B Koletzko
    Kinderpoliklinik, Klinikum Innenstadt der Ludwig Maximilians Universität, Munchen, Germany
    Br J Nutr 80:S5-45. 1998
    ....
  74. doi [TigerKids. Successful health promotion in preschool settings]
    A Strauss
    Dr von Haunersches Kinderspital, Abt Stoffwechsel und Ernährungsmedizin, Lindwurmstrasse 4, Munich, Germany
    Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 54:322-9. 2011
    ..9 vs. 18.0%, p=0.05) and obesity (3.4 vs. 5.4%, p=0.07) in the first year. TigerKids is a low cost program applied in daycare settings which achieves significant behavioral changes in the home environment...
  75. ncbi Plasma fatty acids and [13C]linoleic acid metabolism in preterm infants fed a formula with medium-chain triglycerides
    Maria Rodriguez
    Dr von Hauner Children s Hospital, Ludwig Maximilians University, Munich, Germany
    J Lipid Res 44:41-8. 2003
    ..We conclude that oral MCT effectively reduce polyunsaturated fatty acid and long chain polyunsaturated fatty acid oxidation in preterm infants without compromising endogenous n-6 long chain polyunsaturated fatty acid synthesis...
  76. doi Introduction of complementary feeding in 5 European countries
    Sonia Schiess
    Division of Metabolic Diseases and Nutritional Medicine, Dr von Hauner Children s Hospital, Ludwig Maximilians University, Munchen, Germany
    J Pediatr Gastroenterol Nutr 50:92-8. 2010
    ..Little is known about the practice of introducing complementary feeding across Europe. We aim at describing times of solid introduction in healthy infants in 5 European countries...
  77. ncbi Influence of fish oil or folate supplementation on the time course of plasma redox markers during pregnancy
    Corinna Franke
    Division of Metabolism and Nutrition, Dr V Hauner Children s Hospital, Munich, Germany
    Br J Nutr 103:1648-56. 2010
    ..Fish oil supplementation during the second half of pregnancy appears not to decrease antioxidant status. The increased TBARS levels at week 30 may indicate a period of increased oxidative stress in plasma at this time...
  78. doi Long-chain polyunsaturated fatty acid (LC-PUFA) transfer across the placenta
    Fabienne L Hanebutt
    Division of Metabolic Diseases and Nutritional Medicine, Dr von Hauner Children s Hospital, Ludwig Maximilians University of Munich, Lindwurmstrasse 4, 80337 Munich, Germany
    Clin Nutr 27:685-93. 2008
    ....
  79. ncbi Docosahexaenoic acid supply in pregnancy affects placental expression of fatty acid transport proteins
    Elvira Larque
    Division of Metabolic Diseases and Nutritional Medicine, Dr von Hauner Children Hospital, Ludwig Maximilians University of Munich, Munich, Germany
    Am J Clin Nutr 84:853-61. 2006
    ..Better understanding of the mechanisms involved in docosahexaenoic acid (DHA) transfer to the neonate may contribute to improve dietary support for infants born prematurely to mothers with placental lipid transport disorders...
  80. ncbi Long-term consequences of early feeding on later obesity risk
    Berthold Koletzko
    Division Metabolic Diseases and Nutritional Medicine, Dr von Hauner Children s Hospital, Ludwig Maximilian University of Munich, Munich, Germany
    Nestle Nutr Workshop Ser Pediatr Program 58:1-18. 2006
    ..If an effect of infant feeding habits on later obesity risk should be established, there is great potential for effective preventive intervention with a significant potential health benefit for the child and adult population...
  81. doi [(13)C]Methionine breath test as a marker for hepatic mitochondrial function in HIV-infected patients
    T Sternfeld
    II Medizinische Klinik und Poliklinik, Infektionsambulanz, Klinikum rechts der Isar, Technische Universitat Munchen, Munich, Germany
    AIDS Res Hum Retroviruses 25:1243-8. 2009
    ..Hepatic mitochondrial function is impaired in antiretroviral-treated HIV-infected patients with disturbances of lipid metabolism...
  82. ncbi Losses of vitamin A and E in parenteral nutrition suitable for premature infants
    C Haas
    Division of Metabolic Disorders and Nutrition, University of Munich, Munich, Germany
    Eur J Clin Nutr 56:906-12. 2002
    ..To assess the bioavailability of vitamins A and E administered parenterally with either water-soluble or lipid-soluble preparations...
  83. ncbi Docosahexaenoic acid supplementation in vegetarians effectively increases omega-3 index: a randomized trial
    Julia Geppert
    Division of Metabolic Diseases and Nutrition, Dr von Hauner Children s Hospital, Ludwig Maximilians University of Munich, Munich, Germany
    Lipids 40:807-14. 2005
    ..RBC total FA analyses can be used instead of RBC lipid fraction analyses for assessing essential FA status, e.g., in clinical studies...
  84. doi Effect of docosahexaenoic acid on oxidative stress in placental trophoblast cells
    Hiromichi Shoji
    Division of Metabolic Disorders and Nutrition, Dr von Hauner Children s Hospital, Ludwig Maximilians University, Munich, Germany
    Early Hum Dev 85:433-7. 2009
    ..Docosahexaenoic acid (DHA) is an indispensable component of cell membranes that is required at high levels during pregnancy...
  85. doi Genetically determined variation in polyunsaturated fatty acid metabolism may result in different dietary requirements
    Berthold Koletzko
    Division of Metabolic Diseases and Nutritional Medicine, Dr von Hauner Children s Hospital, University of Munich, Munich, Germany
    Nestle Nutr Workshop Ser Pediatr Program 62:35-44; discussion 44-9. 2008
    ....
  86. ncbi Effect of amino acid infusion on human postoperative colon protein synthesis in situ
    Peter Rittler
    Department of Surgery, Klinikum Grosshadern, Munich, Germany
    JPEN J Parenter Enteral Nutr 29:255-61. 2005
    ..However, no information is available about the effects of amino acids on human intestinal protein metabolism after surgery...
  87. ncbi In vivo investigation of the placental transfer of (13)C-labeled fatty acids in humans
    Elvira Larque
    Division of Metabolism and Nutrition, Kinderklinik and Kinderpoliklinik, Dr von Hauner Children s Hospital, Munich, Germany
    J Lipid Res 44:49-55. 2003
    ..2 +/- 1.3%; [(13)C]DHA, 25.9 +/- 3.4%). These results suggest that only a part of the placental NEFA participated in fatty acid transfer, and that the placenta showed a preferential accretion of DHA relative to the other fatty acids...
  88. ncbi Expression pattern of fatty acid transport protein-1 (FATP-1), FATP-4 and heart-fatty acid binding protein (H-FABP) genes in human term placenta
    Elvira Larque
    Division of Metabolic Diseases and Nutritional Medicine, Dr von Hauner Children s Hospital, Ludwig Maximilians University of Munich Lindwurmstrasse 4, D 80337 München, Germany
    Early Hum Dev 82:697-701. 2006
    ..mRNA expression of FATP-1 and FATP-4 was significantly higher than H-FABP. The expression of L-FABP was too low in placenta for accurate quantification...