Martin Kohrmann

Summary

Affiliation: University of Erlangen-Nuremberg
Country: Germany

Publications

  1. doi request reprint The only evidence based neuroprotective therapy for acute ischemic stroke: thrombolysis
    Martin Kohrmann
    Department of Neurology, University Hospital Erlangen, Germany
    Best Pract Res Clin Anaesthesiol 24:563-71. 2010
  2. doi request reprint Avoiding in hospital delays and eliminating the three-hour effect in thrombolysis for stroke
    Martin Kohrmann
    Department of Neurology, University Hospital of Erlangen, Schwabachanlage 6, 91054 Erlangen, Germany
    Int J Stroke 6:493-7. 2011
  3. doi request reprint The prevalence of peripheral arteriopathy is higher in ischaemic stroke as compared with transient ischaemic attack and intracerebral haemorrhage
    Hagen B Huttner
    Department of Neurology, University of Erlangen, Erlangen, Germany
    Int J Stroke 5:278-83. 2010
  4. doi request reprint Mechanical ventilation in Guillain-Barré syndrome: does age influence functional outcome?
    Martin Kohrmann
    Department of Neurology, University of Heidelberg, Heidelberg, Germany
    Eur Neurol 61:358-63. 2009
  5. doi request reprint MRI mismatch-based intravenous thrombolysis for isolated cerebellar infarction
    Martin Kohrmann
    Department of Neurology, University of Erlangen, Erlangen, Germany
    Stroke 40:1897-9. 2009
  6. doi request reprint Safety and outcome after thrombolysis in stroke patients with mild symptoms
    M Kohrmann
    Department of Neurology, University of Erlangen, Schwabachanlage 6, Erlangen, Germany
    Cerebrovasc Dis 27:160-6. 2009
  7. ncbi request reprint Hemicraniectomy for malignant middle cerebral artery infarction
    Martin Kohrmann
    Department of Neurology, University of Erlangen, Erlangen, Germany
    Curr Opin Crit Care 15:125-30. 2009
  8. doi request reprint The hyperintense acute reperfusion marker on fluid-attenuated inversion recovery magnetic resonance imaging is caused by gadolinium in the cerebrospinal fluid
    Martin Kohrmann
    Department of Neurology, University Hospital of Erlangen, Erlangen, Germany
    Stroke 43:259-61. 2012
  9. ncbi request reprint Acute stroke imaging for thrombolytic therapy--an update
    Martin Kohrmann
    Department of Neurology, University Hospital of Erlangen, Erlangen, Germany
    Cerebrovasc Dis 24:161-9. 2007
  10. doi request reprint Therapy of acute basilar artery occlusion: intraarterial thrombolysis alone vs bridging therapy
    Simon Nagel
    Department of Neurology, University of Heidelberg, INF 400, 69120 Heidelberg, Germany
    Stroke 40:140-6. 2009

Detail Information

Publications59

  1. doi request reprint The only evidence based neuroprotective therapy for acute ischemic stroke: thrombolysis
    Martin Kohrmann
    Department of Neurology, University Hospital Erlangen, Germany
    Best Pract Res Clin Anaesthesiol 24:563-71. 2010
    ..Finally intraarterial approaches as well as combined systemic and interventional therapies are discussed...
  2. doi request reprint Avoiding in hospital delays and eliminating the three-hour effect in thrombolysis for stroke
    Martin Kohrmann
    Department of Neurology, University Hospital of Erlangen, Schwabachanlage 6, 91054 Erlangen, Germany
    Int J Stroke 6:493-7. 2011
    ..Hypothesis We hypothesized that a standardized thrombolysis procedure carried out in a specialized neurological emergency room can minimize in-hospital delays and erase the 'three-hour effect'...
  3. doi request reprint The prevalence of peripheral arteriopathy is higher in ischaemic stroke as compared with transient ischaemic attack and intracerebral haemorrhage
    Hagen B Huttner
    Department of Neurology, University of Erlangen, Erlangen, Germany
    Int J Stroke 5:278-83. 2010
    ..We aimed to assess the prevalence of peripheral arterial disease in acute stroke and to identify the predisposing factors for peripheral arterial disease in a stroke cohort...
  4. doi request reprint Mechanical ventilation in Guillain-Barré syndrome: does age influence functional outcome?
    Martin Kohrmann
    Department of Neurology, University of Heidelberg, Heidelberg, Germany
    Eur Neurol 61:358-63. 2009
    ..To examine the effects of age on differences in the clinical course and functional outcome of mechanically ventilated Guillain-Barré syndrome (GBS) patients...
  5. doi request reprint MRI mismatch-based intravenous thrombolysis for isolated cerebellar infarction
    Martin Kohrmann
    Department of Neurology, University of Erlangen, Erlangen, Germany
    Stroke 40:1897-9. 2009
    ..No specific acute therapy is established, and patients are usually excluded from intravenous thrombolysis (IVT)...
  6. doi request reprint Safety and outcome after thrombolysis in stroke patients with mild symptoms
    M Kohrmann
    Department of Neurology, University of Erlangen, Schwabachanlage 6, Erlangen, Germany
    Cerebrovasc Dis 27:160-6. 2009
    ..We aimed to assess the safety and outcome of thrombolysis therapy in patients with minor but disabling stroke symptoms...
  7. ncbi request reprint Hemicraniectomy for malignant middle cerebral artery infarction
    Martin Kohrmann
    Department of Neurology, University of Erlangen, Erlangen, Germany
    Curr Opin Crit Care 15:125-30. 2009
    ..Several case series had suggested decompressive hemicraniectomy as a life-saving therapy, but, until recently, there was no proof for this procedure from randomized controlled trials...
  8. doi request reprint The hyperintense acute reperfusion marker on fluid-attenuated inversion recovery magnetic resonance imaging is caused by gadolinium in the cerebrospinal fluid
    Martin Kohrmann
    Department of Neurology, University Hospital of Erlangen, Erlangen, Germany
    Stroke 43:259-61. 2012
    ..However, this hypothesis has never been directly verified in humans...
  9. ncbi request reprint Acute stroke imaging for thrombolytic therapy--an update
    Martin Kohrmann
    Department of Neurology, University Hospital of Erlangen, Erlangen, Germany
    Cerebrovasc Dis 24:161-9. 2007
    ....
  10. doi request reprint Therapy of acute basilar artery occlusion: intraarterial thrombolysis alone vs bridging therapy
    Simon Nagel
    Department of Neurology, University of Heidelberg, INF 400, 69120 Heidelberg, Germany
    Stroke 40:140-6. 2009
    ..We compared intraarterial thrombolysis with the combined bridging approach of intravenous abciximab and intraarterial thrombolysis with rt-PA (bridging therapy) in an observational, longitudinal, monocenter study...
  11. doi request reprint MRI in patients with acute basilar artery occlusion - DWI lesion scoring is an independent predictor of outcome
    Simon Nagel
    Department of Neurology, University of Heidelberg, Heidelberg, Germany
    Int J Stroke 7:282-8. 2012
    ..We analyzed early diffusion-weighted magnetic resonance imaging of patients with acute basilar artery occlusion by applying different lesion scoring systems and determined their predictive value for favorable outcome...
  12. doi request reprint Weight approximation in stroke before thrombolysis: the WAIST-Study: a prospective observational "dose-finding" study
    Lorenz Breuer
    Department of Neurology, University of Erlangen Nuremberg, Schwabachanlage 6, 91054 Erlangen, Germany
    Stroke 41:2867-71. 2010
    ..The aim of our study was to evaluate availability of BW information, accuracy of estimations, and final dosing of Alteplase (tissue plasminogen activator [tPA]) in a routine clinical setting...
  13. pmc Retrospective agreement and consent to neurocritical care is influenced by functional outcome
    Ines C Kiphuth
    Department of Neurology, University of Erlangen, Schwabachanlage 6, 91054 Erlangen, Germany
    Crit Care 14:R144. 2010
    ....
  14. doi request reprint Early administration of low molecular weight heparin after spontaneous intracerebral hemorrhage. A safety analysis
    Ines C Kiphuth
    Department of Neurology, University of Erlangen, Schwabachanlage 6, Erlangen, Germany
    Cerebrovasc Dis 27:146-50. 2009
    ..The objective of this study was to assess the safety of early subcutaneous LMWH in patients with sICH with respect to hemorrhage enlargement...
  15. doi request reprint Correlation of age and haematoma volume in patients with spontaneous lobar intracerebral haemorrhage
    Joji B Kuramatsu
    Department of Neurology, University of Erlangen, Schwabachanlage 6, Erlangen, Germany
    J Neurol Neurosurg Psychiatry 82:144-9. 2011
    ..Lobar intracerebral haemorrhage (LH) is gaining importance in the ageing population, but there are only limited data regarding specific clinical characteristics and risk factors of older patients with LH...
  16. doi request reprint MRI criteria in MS patients with negative and positive oligoclonal bands: equal fulfillment of Barkhof's criteria but different lesion patterns
    Hagen B Huttner
    Department of Neurology, University of Erlangen Nuremberg, 91054 Erlangen, Germany
    J Neurol 256:1121-5. 2009
    ..16/22; P = 0.696). Further analyses of MRI findings between OCB-negative and -positive MS patients might contribute to a better pathophysiological understanding of the genesis and evidence of OCB in the CSF of MS patients...
  17. ncbi request reprint Clinical severity predicts time to hospital admission in patients with spontaneous intracerebral hemorrhage
    Hagen B Huttner
    Department of Neurology, University of Erlangen, Erlangen, Germany
    Cerebrovasc Dis 25:533-8. 2008
    ..We a priori hypothesized that the earlier a patient was admitted to hospital, the worse the clinical status would be...
  18. doi request reprint Vasospasm in intracerebral hemorrhage with ventricular involvement: a prospective pilot transcranial Doppler sonography study
    Ines C Kiphuth
    Department of Neurology, University of Erlangen, Erlangen, Germany
    Cerebrovasc Dis 32:420-5. 2011
    ..The incidence and role of VSP in IVH, however, have not been systematically studied...
  19. doi request reprint Ultra-early intravenous stroke thrombolysis: do all patients benefit similarly?
    Daniel Strbian
    From the Departments of Neurology and Stroke Units, Helsinki University Central Hospital, Helsinki, Finland D S, T T Department of Neurology, University of Heidelberg, Heidelberg, Germany P R, W H Department of Neurology, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland P M, A E Department of Neurology, Universitatsklinikum Erlangen, Erlangen, Germany L B, M K Department of Neurology, Tampere University Hospital, Tampere, Finland J O, H N Department of Neurology, University Lille Nord de France K M, D L Department of Neurology and Stroke Units, University Hospital Basel, Basel, Switzerland D J S, H G, S E Department of Neurology, University of Bern, Bern, Switzerland S J, B W, H P M Department of Neurology, Hospital Clinic Institut d Investigacions Biomediques August Pi i Sunyer, Barcelona, Spain V O, A C and Department of Neurology, Kantonsspital St Gallen
    Stroke 44:2913-6. 2013
    ..We now explored in a large multicenter cohort whether extra benefit of treatment within 90 minutes from symptom onset is uniform across predefined stroke severity subgroups, as compared with later thrombolysis...
  20. doi request reprint Glycosylated hemoglobin A1 predicts risk for symptomatic hemorrhage after thrombolysis for acute stroke
    Andrea Rocco
    Department of Neurology, University of Heidelberg, Heidelberg, Germany
    Stroke 44:2134-8. 2013
    ..Symptomatic intracerebral hemorrhage (sICH) is the most feared acute complication after intravenous thrombolysis. The aim of this study was to determine the predictive value of parameters of glycosylated hemoglobin A1 (HbA1c) on sICH...
  21. doi request reprint Neuroendocrine changes in patients with spontaneous supratentorial intracerebral hemorrhage
    Hagen B Huttner
    Department of Neurology, University of Erlangen, Schwabachanlage 6, 91054, Erlangen, Germany
    Neurocrit Care 18:39-44. 2013
    ..As there are no corresponding data in patients with intracerebral hemorrhage (ICH) we analyzed various neuroendocrine parameters to investigate possible alterations in hormone profiles of patients with ICH...
  22. pmc Predictors for good functional outcome after neurocritical care
    Ines C Kiphuth
    Department of Neurology, University of Erlangen, Schwabachanlage 6, 91054 Erlangen, Germany
    Crit Care 14:R136. 2010
    ..In this study we analyzed survival, long-term mortality and functional outcome after neurocritical care and determined predictors for good functional outcome...
  23. ncbi request reprint Hematoma growth and outcome in treated neurocritical care patients with intracerebral hemorrhage related to oral anticoagulant therapy: comparison of acute treatment strategies using vitamin K, fresh frozen plasma, and prothrombin complex concentrates
    Hagen B Huttner
    Department of Neurology, University of Heidelberg, Germany
    Stroke 37:1465-70. 2006
    ..The aim of the present study was to compare the acute treatment strategies of OAT-associated ICH using vitamin K (VAK), fresh frozen plasma (FFP), and prothrombin complex concentrates (PCCs) with regard to hematoma growth and outcome...
  24. ncbi request reprint Therapy for early reperfusion after stroke
    Eric Juttler
    Department of Neurology, University of Heidelberg, Im Neuenheimer Feld 400, D 69120 Heidelberg, Germany
    Nat Clin Pract Cardiovasc Med 3:656-63. 2006
    ..Other therapies, such as antiplatelet agents (i.e. glycoprotein IIb/IIIa inhibitors), and anticoagulant drugs will be discussed briefly...
  25. ncbi request reprint Hyponatremia is an independent predictor of in-hospital mortality in spontaneous intracerebral hemorrhage
    Joji B Kuramatsu
    From the Departments of Neurology J B K, T B, B V, D S, M K, H B H and Neuroradiology H L, S P K, University of Erlangen Nuremberg, Erlangen, Germany
    Stroke 45:1285-91. 2014
    ..This the first study that investigated the prevalence and clinical associations of hyponatremia in patients with ICH...
  26. doi request reprint Reported antiplatelet use influences long-term outcome independently in deep intracerebral hemorrhage
    Joji B Kuramatsu
    Department of Neurology, University of Erlangen, Erlangen, Germany
    Neurosurgery 70:342-50; discussion 350. 2012
    ..Several outcome predictors have been debated, but influences on mortality and outcome still remain controversial, especially for different ICH locations...
  27. doi request reprint MRI of the perihemorrhagic zone in a rat ICH model: effect of hematoma evacuation
    Berk Orakcioglu
    Department of Neurosurgery, University Hospital Heidelberg, Im Neuenheimer Feld 400, Heidelberg, Germany
    Neurocrit Care 8:448-55. 2008
    ..Recently, ischemic changes in the perihemorrhagic zone (PHZ) have been discussed as a potential source of secondary damage. In this study, we focussed on diffusion and perfusion characteristics of experimental ICH...
  28. ncbi request reprint Penumbra Stroke System as an "add-on" for the treatment of large vessel occlusive disease following thrombolysis: first results
    Tobias Struffert
    Department of Neuroradiology, University of Erlangen Nuremberg, Schwabachanlage 6, Erlangen 91054, Germany
    Eur Radiol 19:2286-93. 2009
    ..The recanalisation rate was 80%. Symptomatic haemorrhage did not occur. Randomized trials may demonstrate that endovascular mechanical thrombectomy improves patient outcome...
  29. doi request reprint A structured reading algorithm improves telemetric detection of atrial fibrillation after acute ischemic stroke
    Bernd Kallmünzer
    Department of Neurology, University Medical Center Erlangen, Schwabachanlage 6, 91054 Erlangen, Germany
    Stroke 43:994-9. 2012
    ..In this study, the sensitivity of AF detection was assessed for serial electrocardiographic recordings and continuous stroke unit telemetric monitoring with or without a structured algorithm to analyze telemetric data (SEA-AF)...
  30. doi request reprint Ice-cold saline for the induction of mild hypothermia in patients with acute ischemic stroke: a pilot study
    Rainer Kollmar
    Department of Neurology, University of Erlangen Nuernberg, Erlangen, Germany
    Stroke 40:1907-9. 2009
    ..Preliminary studies in cardiac arrest patients indicate that rapid infusion of ice cold saline (ICS) is safe and effective for induction of hypothermia. We investigated its use in patients with acute ischemic stroke (AIS)...
  31. doi request reprint The safety and usefulness of low molecular weight heparins and unfractionated heparins in patients with acute stroke
    Ines C Kiphuth
    University of Erlangen, Department of Neurology, Schwabachanlage 6, 91054 Erlangen, Germany
    Expert Opin Drug Saf 8:585-97. 2009
    ....
  32. doi request reprint Optimized intravenous Flat Detector CT for non-invasive visualization of intracranial stents: first results
    Tobias Struffert
    Department of Neuroradiology, University of Erlangen Nuremberg, Erlangen, Germany
    Eur Radiol 21:411-8. 2011
    ..Residual stenosis (RS) is not rare. We evaluated an optimised Flat Detector CT protocol with intravenous contrast material application (i.v. FD-CTA) for non-invasive follow-up...
  33. ncbi request reprint MRI-based and CT-based thrombolytic therapy in acute stroke within and beyond established time windows: an analysis of 1210 patients
    Peter D Schellinger
    Department of Neurology, University of Erlangen, Schwabachanlage 6, D 91054 Erlangen, Germany
    Stroke 38:2640-5. 2007
    ..This window may be extended by using modern imaging-based selection algorithms. We assessed safety and efficacy of MRI-based thrombolysis within and beyond 3 hours compared with standard CT-based thrombolysis...
  34. doi request reprint Serious cardiac arrhythmias after stroke: incidence, time course, and predictors--a systematic, prospective analysis
    Bernd Kallmünzer
    Department of Neurology, University Medical Center Erlangen, Schwabachanlage 6, 91054 Erlangen, Germany
    Stroke 43:2892-7. 2012
    ..Patients with acute cerebrovascular events are susceptible to serious cardiac arrhythmias, but data on the time course and the determinants of their onset are scarce...
  35. doi request reprint Sonographic monitoring of midline shift predicts outcome after intracerebral hemorrhage
    Ines C Kiphuth
    Department of Neurology, Universitatsklinikum Erlangen, Erlangen, Germany
    Cerebrovasc Dis 34:297-304. 2012
    ..In this observational study, we monitored MLS with TDS in patients with supratentorial ICH up to day 14 after the ictus, and then correlated MLS with the outcome 6 months after hospital discharge...
  36. ncbi request reprint MRI versus CT-based thrombolysis treatment within and beyond the 3 h time window after stroke onset: a cohort study
    Martin Kohrmann
    Department of Neurology, University of Heidelberg, Heidelberg, Germany
    Lancet Neurol 5:661-7. 2006
    ..We assessed the safety and efficacy of an MRI-based selection protocol for stroke treatment within and beyond 3 h compared with standard CT-based treatment...
  37. ncbi request reprint Influence of intraventricular hemorrhage and occlusive hydrocephalus on the long-term outcome of treated patients with basal ganglia hemorrhage: a case-control study
    Hagen B Huttner
    Department of Neurology, University of Heidelberg, Germany
    J Neurosurg 105:412-7. 2006
    ..The aim of this study was to compare the long-term outcome of patients with pure ganglionic hemorrhage and those requiring an EVD due to additional IVH and hydrocephalus...
  38. ncbi request reprint Predictive factors for tracheostomy in neurocritical care patients with spontaneous supratentorial hemorrhage
    Hagen B Huttner
    Department of Neurology, University of Heidelberg, Heidelberg, Germany
    Cerebrovasc Dis 21:159-65. 2006
    ....
  39. ncbi request reprint Doppler pulsatility index in spontaneous intracerebral hemorrhage
    Ines C Kiphuth
    Department of Neurology, University of Erlangen Nuremberg, Erlangen, Germany
    Eur Neurol 70:133-8. 2013
    ..This study aims to investigate whether PI correlates with ICP and midline shift and serves as a reliable predictor of functional outcome in patients with ICH...
  40. ncbi request reprint Impaired renal function in stroke patients with atrial fibrillation
    Eva Maria Sauer
    Department of Neurology, Universitatsklinikum Erlangen, Erlangen, Germany Electronic address
    J Stroke Cerebrovasc Dis 23:1225-8. 2014
    ..In this study, we analyzed frequency and predictors for impaired renal function and its impact on functional outcome in stroke patients with underlying AF...
  41. doi request reprint Autonomic blockade during sinusoidal baroreflex activation proves sympathetic modulation of cerebral blood flow velocity
    Max J Hilz
    Department of Neurology, University of Erlangen Nuremberg, Erlangen, Germany
    Stroke 44:1062-9. 2013
    ..This study evaluated by pharmacological blockade whether 0.1 Hz CBFV oscillations are related to sympathetic and 0.2 Hz CBFV oscillations to parasympathetic modulation...
  42. doi request reprint Long-term outcome after surgical treatment for space-occupying cerebellar infarction: experience in 56 patients
    Eric Juttler
    Department of Neurology, University of Heidelberg, Heidelberg, Germany
    Stroke 40:3060-6. 2009
    ....
  43. doi request reprint Hemicraniectomy for malignant middle cerebral artery infarction: retrospective consent to decompressive surgery depends on functional long-term outcome
    Ines C Kiphuth
    Department of Neurology, University of Erlangen, Schwabachanlage 6, 91054, Erlangen, Germany
    Neurocrit Care 13:380-4. 2010
    ..This study analyzed the patients' retrospective consent to hemicraniectomy in light of the experienced functional outcome 12 months after hospital stay...
  44. ncbi request reprint Noninvasive angiography (magnetic resonance and computed tomography) in the diagnosis of ischemic cerebrovascular disease. Techniques and clinical applications
    Peter D Schellinger
    Department of Neurology, University of Erlangen, Erlangen, Germany
    Cerebrovasc Dis 24:16-23. 2007
    ..The contribution of noninvasive vascular imaging to vascular malformations (including aneurysms, fistulas and cerebral-vein thrombosis) is beyond the scope of this paper and therefore not covered...
  45. ncbi request reprint Intracerebral hemorrhage with severe ventricular involvement: lumbar drainage for communicating hydrocephalus
    Hagen B Huttner
    Department of Neurology, University of Erlangen, Germany
    Stroke 38:183-7. 2007
    ....
  46. ncbi request reprint Clinical/perfusion CT CBV mismatch as prognostic factor in intraarterial thrombectomy in acute anterior circulation stroke
    Marc Saake
    Department of Neuroradiology, University of Erlangen Nuremberg, Schwabachanlage 6, 91054 Erlangen, Germany Electronic address
    Clin Neurol Neurosurg 121:39-45. 2014
    ..We assessed whether a clinical/perfusion CT cerebral blood volume (CBV) mismatch concept (CPM) can identify patients who will benefit from reperfusion therapy...
  47. doi request reprint Standardized antipyretic treatment in stroke: a pilot study
    Bernd Kallmünzer
    Department of Neurology, University Medical Center Erlangen Nuremberg, Germany
    Cerebrovasc Dis 31:382-9. 2011
    ..This study investigated an institutional standard operating procedure (SOP) for fever treatment in stroke patients including a sequence of pharmacologic and physical interventions...
  48. doi request reprint Relationship between onset-to-door time and door-to-thrombolysis time: a pooled analysis of 10 dedicated stroke centers
    Daniel Strbian
    From the Department of Neurology and Stroke Unit, Helsinki University Central Hospital, Helsinki, Finland D S, M T, T T Department of Neurology and Stroke Unit, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland P M, A E Department of Neurology and Stroke Unit, University of Heidelberg, Heidelberg, Germany P R, C G, W H Department of Neurology and Stroke Unit, Tampere University Hospital, Tampere, Finland H N, A K P Department of Neurology and Stroke Unit, Universitatsklinikum Erlangen, Erlangen, Germany L B, M K Department of Neurology and Stroke Unit, University Lille Nord de France M B, D L Department of Neurology and Stroke Unit, University Hospital Basel, Basel, Switzerland D J S, H G, S T E Department of Neurology and Stroke Unit, University of Bern, Bern, Switzerland S J, B W, H P M Department of Neurology and Stroke Unit, Hospital Clinic Institut d Investigacions Biomediques August Pi i Sunyer, Barcelona, Tumor Marker Oncology Research Centre
    Stroke 44:2808-13. 2013
    ..Inverse relationship between onset-to-door time (ODT) and door-to-needle time (DNT) in stroke thrombolysis was reported from various registries. We analyzed this relationship and other determinants of DNT in dedicated stroke centers...
  49. doi request reprint Increased membrane shedding--indicated by an elevation of CD133-enriched membrane particles--into the CSF in partial epilepsy
    Hagen B Huttner
    Epilepsy Center, Department of Neurology, University of Erlangen, Schwabachanlage 6, 91054 Erlangen, Germany
    Epilepsy Res 99:101-6. 2012
    ..As adult neurogenesis has been implicated to be induced by epileptic seizures this study investigated whether patients with partial epilepsy show a varying amount of membrane-associated CD133 in CSF as compared to healthy adults...
  50. ncbi request reprint Hemorrhagic complications after off-label thrombolysis for ischemic stroke
    Aitziber Aleu
    Department of Neurology, Neurointensive Care Unit, University of Heidelberg, Heidelberg, Germany
    Stroke 38:417-22. 2007
    ..Safety of intravenous and intraarterial thrombolysis in off-label situations is controversially discussed. We sought to review the reports on such patients regarding intra- and extracranial hemorrhage...
  51. doi request reprint Improved detection of silent atrial fibrillation using 72-hour Holter ECG in patients with ischemic stroke: a prospective multicenter cohort study
    Martin Grond
    From the Department of Neurology, Kreisklinikum Siegen, Siegen, Germany M G Department of Neurology, Hainich Klinikum, Mühlhausen, Germany M J Department of Neurology, HSK Klinik, Wiesbaden, Germany G H Department of Neurology, Klinikum Offenbach, Offenbach, Germany E S Department of Neurology, University of Heidelberg, Germany R V Department of Neurology, Vivantes Klinikum Neukölln, Berlin, Germany D N Department of Neurology, Klinikum Bad Hersfeld, Bad Hersfeld, Germany M H Department of Neurology, University of Essen, Germany C W Department of Neurology, University of Erlangen, Germany M K Department of Neurology, University of Gottingen, Germany R W Sanofi Aventis Deutschland, Berlin, Germany L R and University of Birmingham Centre for Cardiovascular Sciences, Birmingham, UK, and Department of Cardiovascular Medicine and Atrial Fibrillation competence NETwork AFNET, University Hospital Munster, Germany P K
    Stroke 44:3357-64. 2013
    ..Prolonged ECG monitoring may improve the detection of paroxysmal, previously undiagnosed AF (unknown AF). Therefore, we evaluated systematic 72-hour Holter ECG monitoring to detect unknown AF for the workup of patients with stroke...
  52. ncbi request reprint Comparison of ABC/2 estimation technique to computer-assisted planimetric analysis in warfarin-related intracerebral parenchymal hemorrhage
    Hagen B Huttner
    Department of Neurology, University of Heidelberg, Heidelberg, Germany
    Stroke 37:404-8. 2006
    ..Our objective was to validate the ABC/2 technique based on analyses of the hematoma shapes in OAT-related ICH...
  53. ncbi request reprint Hypothermia in acute stroke--slow versus fast rewarming an experimental study in rats
    Christian Berger
    Department of Neurology, University of Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany
    Exp Neurol 204:131-7. 2007
    ..It may blunt deleterious rebound effects such as overexpression of AQP4, sustain anti-inflammatory mechanisms and thereby preserve the neuroprotection delivered by hypothermia...
  54. doi request reprint Novel approaches to the treatment of intracerebral haemorrhage
    Dimitre Staykov
    Department of Neurology, University Clinic Erlangen, Schwabachanlage 6, 91054 Erlangen, Germany
    Int J Stroke 5:457-65. 2010
    ..Several novel aspects of treatment of spontaneous intracerebral haemorrhage are reviewed in the present article...
  55. ncbi request reprint The stem cell marker prominin-1/CD133 on membrane particles in human cerebrospinal fluid offers novel approaches for studying central nervous system disease
    Hagen B Huttner
    Tissue Engineering Laboratories, Biotechnology Center BIOTEC, Technische Universitat Dresden, Tatzberg 47 51, 01307 Dresden, Germany
    Stem Cells 26:698-705. 2008
    ..Hence, analysis of CSF for membrane particles carrying the somatic stem cell marker prominin-1/CD133 offers a novel approach for studying human central nervous system disease...
  56. doi request reprint Combining magnetic resonance imaging within six-hours of symptom onset with clinical follow-up at 24 h improves prediction of 'malignant' middle cerebral artery infarction
    Anna Kruetzelmann
    Department of Neurology, University Hospital Hamburg Eppendorf, Hamburg, Germany
    Int J Stroke 9:210-4. 2014
    ....
  57. doi request reprint Stroke-MRI: extending the time-window: recent trials and clinical practice
    Martin Kohrmann
    Department of Neurology, University of Erlangen, Germany
    Int J Stroke 2:53-4. 2007
  58. ncbi request reprint Linezolid-induced posterior reversible leukoencephalopathy syndrome
    Simon Nagel
    Department of Neurology, University of Heidelberg, Heidelberg, Germany
    Arch Neurol 64:746-8. 2007
    ....
  59. doi request reprint Ischemic stroke in an obese patient receiving dabigatran
    Lorenz Breuer
    University of Erlangen Nuremberg, Erlangen, Germany
    N Engl J Med 368:2440-2. 2013
    ..7) with atrial fibrillation who was receiving dabigatran for thromboprophylaxis presented with an ischemic stroke. Dabigatran levels during observed administration were less than the 25th percentile of the therapeutic trough level...