Affiliation: University of Regensburg
- Active DNA demethylation in human postmitotic cells correlates with activating histone modifications, but not transcription levelsMaja Klug
Department of Hematology, University Hospital Regensburg, Franz Josef Strauss Allee 11, 93042 Regensburg, Germany
Genome Biol 11:R63. 2010..Previous work has largely focused on proliferating cell types that are mitotically arrested using pharmacological inhibitors to distinguish between active and passive mechanisms of DNA demethylation...
- General transcription factor binding at CpG islands in normal cells correlates with resistance to de novo DNA methylation in cancer cellsClaudia Gebhard
Department of Hematology and Institute of Pathology, University Hospital Regensburg, D 93042 Regensburg, Germany
Cancer Res 70:1398-407. 2010..Second, our results suggest that the majority of de novo methylated CpG islands are characterized by the lack of sequence motif combinations and the absence of activating TF binding...
- CCAAT enhancer-binding protein beta regulates constitutive gene expression during late stages of monocyte to macrophage differentiationThu Hang Pham
Department of Hematology and Oncology, University Hospital Regensburg, Regensburg, Germany
J Biol Chem 282:21924-33. 2007..Our data suggest an important constitutive gene regulatory function for C/EBPbeta in differentiated macrophages but not in human blood monocytes...
- Lineage-specific DNA methylation in T cells correlates with histone methylation and enhancer activityChristian Schmidl
Department of Hematology, University Hospital Regensburg, 93042 Regensburg, Germany
Genome Res 19:1165-74. 2009....
- Dap12 expression in activated microglia from retinoschisin-deficient retina and its PU.1-dependent promoter regulationKarin Weigelt
Institute of Human Genetics, University of Regensburg, University of Regensburg, Franz Josef Strauss Allee 11, 93053 Regensburg, Germany
J Leukoc Biol 82:1564-74. 2007..1, and PU.1 controls the myeloid-specific regulation of Dap12 directly and may also play a general role in microglia gene expression during retinal degeneration...