Maja Klug

Summary

Affiliation: University of Regensburg
Country: Germany

Publications

  1. pmc Active DNA demethylation in human postmitotic cells correlates with activating histone modifications, but not transcription levels
    Maja Klug
    Department of Hematology, University Hospital Regensburg, Franz Josef Strauss Allee 11, 93042 Regensburg, Germany
    Genome Biol 11:R63. 2010
  2. doi request reprint General transcription factor binding at CpG islands in normal cells correlates with resistance to de novo DNA methylation in cancer cells
    Claudia Gebhard
    Department of Hematology and Institute of Pathology, University Hospital Regensburg, D 93042 Regensburg, Germany
    Cancer Res 70:1398-407. 2010
  3. ncbi request reprint CCAAT enhancer-binding protein beta regulates constitutive gene expression during late stages of monocyte to macrophage differentiation
    Thu Hang Pham
    Department of Hematology and Oncology, University Hospital Regensburg, Regensburg, Germany
    J Biol Chem 282:21924-33. 2007
  4. pmc Lineage-specific DNA methylation in T cells correlates with histone methylation and enhancer activity
    Christian Schmidl
    Department of Hematology, University Hospital Regensburg, 93042 Regensburg, Germany
    Genome Res 19:1165-74. 2009
  5. ncbi request reprint Dap12 expression in activated microglia from retinoschisin-deficient retina and its PU.1-dependent promoter regulation
    Karin Weigelt
    Institute of Human Genetics, University of Regensburg, University of Regensburg, Franz Josef Strauss Allee 11, 93053 Regensburg, Germany
    J Leukoc Biol 82:1564-74. 2007

Collaborators

Detail Information

Publications5

  1. pmc Active DNA demethylation in human postmitotic cells correlates with activating histone modifications, but not transcription levels
    Maja Klug
    Department of Hematology, University Hospital Regensburg, Franz Josef Strauss Allee 11, 93042 Regensburg, Germany
    Genome Biol 11:R63. 2010
    ..Previous work has largely focused on proliferating cell types that are mitotically arrested using pharmacological inhibitors to distinguish between active and passive mechanisms of DNA demethylation...
  2. doi request reprint General transcription factor binding at CpG islands in normal cells correlates with resistance to de novo DNA methylation in cancer cells
    Claudia Gebhard
    Department of Hematology and Institute of Pathology, University Hospital Regensburg, D 93042 Regensburg, Germany
    Cancer Res 70:1398-407. 2010
    ..Second, our results suggest that the majority of de novo methylated CpG islands are characterized by the lack of sequence motif combinations and the absence of activating TF binding...
  3. ncbi request reprint CCAAT enhancer-binding protein beta regulates constitutive gene expression during late stages of monocyte to macrophage differentiation
    Thu Hang Pham
    Department of Hematology and Oncology, University Hospital Regensburg, Regensburg, Germany
    J Biol Chem 282:21924-33. 2007
    ..Our data suggest an important constitutive gene regulatory function for C/EBPbeta in differentiated macrophages but not in human blood monocytes...
  4. pmc Lineage-specific DNA methylation in T cells correlates with histone methylation and enhancer activity
    Christian Schmidl
    Department of Hematology, University Hospital Regensburg, 93042 Regensburg, Germany
    Genome Res 19:1165-74. 2009
    ....
  5. ncbi request reprint Dap12 expression in activated microglia from retinoschisin-deficient retina and its PU.1-dependent promoter regulation
    Karin Weigelt
    Institute of Human Genetics, University of Regensburg, University of Regensburg, Franz Josef Strauss Allee 11, 93053 Regensburg, Germany
    J Leukoc Biol 82:1564-74. 2007
    ..1, and PU.1 controls the myeloid-specific regulation of Dap12 directly and may also play a general role in microglia gene expression during retinal degeneration...