Luisa Klotz

Summary

Affiliation: University of Bonn
Country: Germany

Publications

  1. request reprint
    Klotz L, Dani I, Edenhofer F, Nolden L, Evert B, Paul B, et al. Peroxisome proliferator-activated receptor gamma control of dendritic cell function contributes to development of CD4+ T cell anergy. J Immunol. 2007;178:2122-31 pubmed
    ..Collectively, our data support the notion that PPARgamma is an efficient regulator of DC immunogenicity that may be exploited to deliberately target CD4(+) T cell-mediated immune responses. ..
  2. Klotz L, Schmidt S, Heun R, Klockgether T, Kolsch H. Association of the PPARgamma gene polymorphism Pro12Ala with delayed onset of multiple sclerosis. Neurosci Lett. 2009;449:81-3 pubmed publisher
    ..Our population-based study demonstrates that the Pro12Ala polymorphism resulting in an amino acid exchange in the N-terminal sequence of PPARgamma may influence the onset of MS. ..
  3. request reprint
    Klotz L, Diehl L, Dani I, Neumann H, von Oppen N, Dolf A, et al. Brain endothelial PPARgamma controls inflammation-induced CD4+ T cell adhesion and transmigration in vitro. J Neuroimmunol. 2007;190:34-43 pubmed
    ..We therefore propose that PPARgamma in brain EC may be exploited to target detrimental EC-T cell interactions under inflammatory conditions. ..
  4. Klotz L, Hucke S, Thimm D, Classen S, Gaarz A, Schultze J, et al. Increased antigen cross-presentation but impaired cross-priming after activation of peroxisome proliferator-activated receptor gamma is mediated by up-regulation of B7H1. J Immunol. 2009;183:129-36 pubmed publisher
    ..g., in T cell-mediated autoimmunity. ..

Locale

Detail Information

Publications4

  1. request reprint
    Klotz L, Dani I, Edenhofer F, Nolden L, Evert B, Paul B, et al. Peroxisome proliferator-activated receptor gamma control of dendritic cell function contributes to development of CD4+ T cell anergy. J Immunol. 2007;178:2122-31 pubmed
    ..Collectively, our data support the notion that PPARgamma is an efficient regulator of DC immunogenicity that may be exploited to deliberately target CD4(+) T cell-mediated immune responses. ..
  2. Klotz L, Schmidt S, Heun R, Klockgether T, Kolsch H. Association of the PPARgamma gene polymorphism Pro12Ala with delayed onset of multiple sclerosis. Neurosci Lett. 2009;449:81-3 pubmed publisher
    ..Our population-based study demonstrates that the Pro12Ala polymorphism resulting in an amino acid exchange in the N-terminal sequence of PPARgamma may influence the onset of MS. ..
  3. request reprint
    Klotz L, Diehl L, Dani I, Neumann H, von Oppen N, Dolf A, et al. Brain endothelial PPARgamma controls inflammation-induced CD4+ T cell adhesion and transmigration in vitro. J Neuroimmunol. 2007;190:34-43 pubmed
    ..We therefore propose that PPARgamma in brain EC may be exploited to target detrimental EC-T cell interactions under inflammatory conditions. ..
  4. Klotz L, Hucke S, Thimm D, Classen S, Gaarz A, Schultze J, et al. Increased antigen cross-presentation but impaired cross-priming after activation of peroxisome proliferator-activated receptor gamma is mediated by up-regulation of B7H1. J Immunol. 2009;183:129-36 pubmed publisher
    ..g., in T cell-mediated autoimmunity. ..