Joachim Klosterkotter

Summary

Affiliation: University of Cologne
Country: Germany

Publications

  1. ncbi request reprint [Prevention of psychotic disorders]
    J Klosterkotter
    Klinik und Poliklinik fur Psychiatrie und Psychotherapie, Klinikum der Universität zu Köln, Kerpener Str 62, 50924, Koln, Deutschland
    Nervenarzt 84:1299, 1302-9. 2013
  2. pmc Indicated prevention of schizophrenia
    Joachim Klosterkotter
    Klinik fur Psychiatrie und Psychotherapie, Universitat zu Koln, Kerpener Strasse 62, Koln, Germany
    Dtsch Arztebl Int 105:532-9. 2008
  3. ncbi request reprint [What is the effect of trauma in post traumatic stress disorder?]
    J Klosterkotter
    Klinik und Poliklinik fur Psychiatrie und Psychotherapie, Universitat zu Koln
    Fortschr Neurol Psychiatr 73:375-6. 2005
  4. ncbi request reprint [For: "Every person with schizophrenia should be treated as early as possible"]
    Joachim Klosterkotter
    Klinik und Poliklinik fur Psychiatrie und Psychotherapie, Universitat zu Koln
    Psychiatr Prax 33:105-6. 2006
  5. doi request reprint Kraepelin and psychotic prodromal conditions
    Joachim Klosterkotter
    Dept of Psychiatry and Psychotherapy, University of Cologne, 50924, Cologne, Germany
    Eur Arch Psychiatry Clin Neurosci 258:74-84. 2008
  6. doi request reprint Binocular depth inversion as a paradigm of reduced visual information processing in prodromal state, antipsychotic-naïve and treated schizophrenia
    Dagmar Koethe
    Dept of Psychiatry and Psychotherapy, University of Cologne, Kerpener Str 62, 50924, Cologne, Germany
    Eur Arch Psychiatry Clin Neurosci 259:195-202. 2009
  7. ncbi request reprint Disturbances of visual information processing in early states of psychosis and experimental delta-9-tetrahydrocannabinol altered states of consciousness
    Dagmar Koethe
    Department of Psychiatry and Psychotherapy, University of Cologne, 50924 Cologne, Germany
    Schizophr Res 88:142-50. 2006
  8. doi request reprint Early detection of psychosis - establishing a service for persons at risk
    Frauke Schultze-Lutter
    University of Cologne, Department of Psychiatry and Psychotherapy, 50924 Cologne, Germany
    Eur Psychiatry 24:1-10. 2009
  9. ncbi request reprint Neurocognitive indicators for a conversion to psychosis: comparison of patients in a potentially initial prodromal state who did or did not convert to a psychosis
    Ralf Pukrop
    Department of Psychiatry and Psychotherapy, University of Cologne, Kerpener Str 62, D 50937 Cologne, Germany
    Schizophr Res 92:116-25. 2007
  10. doi request reprint Successful deep brain stimulation of the nucleus accumbens in severe alcohol dependence is associated with changed performance monitoring
    Jens Kuhn
    Department of Psychiatry and Psychotherapy, University of Cologne, Germany
    Addict Biol 16:620-3. 2011

Collaborators

Detail Information

Publications64

  1. ncbi request reprint [Prevention of psychotic disorders]
    J Klosterkotter
    Klinik und Poliklinik fur Psychiatrie und Psychotherapie, Klinikum der Universität zu Köln, Kerpener Str 62, 50924, Koln, Deutschland
    Nervenarzt 84:1299, 1302-9. 2013
    ..Prior to administration careful risk-benefit analyses have to be carried out for each individual case. ..
  2. pmc Indicated prevention of schizophrenia
    Joachim Klosterkotter
    Klinik fur Psychiatrie und Psychotherapie, Universitat zu Koln, Kerpener Strasse 62, Koln, Germany
    Dtsch Arztebl Int 105:532-9. 2008
    ..For this reason, centers for the early recognition of schizophrenic disorders have come into existence worldwide. In these centers, much effort is devoted to the development and testing of suitable preventive strategies...
  3. ncbi request reprint [What is the effect of trauma in post traumatic stress disorder?]
    J Klosterkotter
    Klinik und Poliklinik fur Psychiatrie und Psychotherapie, Universitat zu Koln
    Fortschr Neurol Psychiatr 73:375-6. 2005
  4. ncbi request reprint [For: "Every person with schizophrenia should be treated as early as possible"]
    Joachim Klosterkotter
    Klinik und Poliklinik fur Psychiatrie und Psychotherapie, Universitat zu Koln
    Psychiatr Prax 33:105-6. 2006
  5. doi request reprint Kraepelin and psychotic prodromal conditions
    Joachim Klosterkotter
    Dept of Psychiatry and Psychotherapy, University of Cologne, 50924, Cologne, Germany
    Eur Arch Psychiatry Clin Neurosci 258:74-84. 2008
    ..This review will outline the current state of the art of a phase specific early detection and intervention based on these syndromes...
  6. doi request reprint Binocular depth inversion as a paradigm of reduced visual information processing in prodromal state, antipsychotic-naïve and treated schizophrenia
    Dagmar Koethe
    Dept of Psychiatry and Psychotherapy, University of Cologne, Kerpener Str 62, 50924, Cologne, Germany
    Eur Arch Psychiatry Clin Neurosci 259:195-202. 2009
    ..70. Thus, the BDII may be useful as an additional neuropsychological test for assessment of patients at high risk for developing schizophrenia...
  7. ncbi request reprint Disturbances of visual information processing in early states of psychosis and experimental delta-9-tetrahydrocannabinol altered states of consciousness
    Dagmar Koethe
    Department of Psychiatry and Psychotherapy, University of Cologne, 50924 Cologne, Germany
    Schizophr Res 88:142-50. 2006
    ....
  8. doi request reprint Early detection of psychosis - establishing a service for persons at risk
    Frauke Schultze-Lutter
    University of Cologne, Department of Psychiatry and Psychotherapy, 50924 Cologne, Germany
    Eur Psychiatry 24:1-10. 2009
    ..The establishment phase of an early detection centre for prodromal psychosis is introduced and characterised, along with its detaining and promoting factors within a universal multi-payer health care system...
  9. ncbi request reprint Neurocognitive indicators for a conversion to psychosis: comparison of patients in a potentially initial prodromal state who did or did not convert to a psychosis
    Ralf Pukrop
    Department of Psychiatry and Psychotherapy, University of Cologne, Kerpener Str 62, D 50937 Cologne, Germany
    Schizophr Res 92:116-25. 2007
    ....
  10. doi request reprint Successful deep brain stimulation of the nucleus accumbens in severe alcohol dependence is associated with changed performance monitoring
    Jens Kuhn
    Department of Psychiatry and Psychotherapy, University of Cologne, Germany
    Addict Biol 16:620-3. 2011
    ..Thus, this case supports the hypothesis that DBS of the NAc could have a positive effect on addiction trough a normalization of craving associated with aMCC dysfunction...
  11. doi request reprint Prediction of psychosis by mismatch negativity
    Mitja Bodatsch
    Department of Psychiatry and Psychotherapy, University of Cologne, Germany
    Biol Psychiatry 69:959-66. 2011
    ..To this aim, mismatch negativity (MMN) was investigated in a sample clinically at high risk, comparing individuals with and without subsequent conversion to psychosis...
  12. doi request reprint Randomized controlled multicentre trial of cognitive behaviour therapy in the early initial prodromal state: effects on social adjustment post treatment
    Andreas Bechdolf
    Department of Psychiatry and Psychotherapy, University of Cologne, Cologne, Germany
    Early Interv Psychiatry 1:71-8. 2007
    ....
  13. pmc Basic symptoms and ultrahigh risk criteria: symptom development in the initial prodromal state
    Frauke Schultze-Lutter
    Department of Psychiatry and Psychotherapy, University of Cologne, 50924 Cologne, Germany
    Schizophr Bull 36:182-91. 2010
    ..However, as regards the criteria, the results support the notion of BS as at least a complementary approach to the ultrahigh risk criteria, which may also allow for an earlier detection of psychosis...
  14. ncbi request reprint Neurocognitive functioning in subjects at risk for a first episode of psychosis compared with first- and multiple-episode schizophrenia
    Ralf Pukrop
    Department of Psychiatry and Psychotherapy, University of Cologne, Cologne, Germany
    J Clin Exp Neuropsychol 28:1388-407. 2006
    ..Results support a neurodevelopmental model of psychosis with further progressive mechanisms and are consistent with a primary involvement of left frontotemporal networks in the prodromal phase...
  15. doi request reprint Unilateral deep brain stimulation of the nucleus accumbens in patients with treatment-resistant obsessive-compulsive disorder: Outcomes after one year
    Wolfgang Huff
    Department of Psychiatry and Psychotherapy, University of Cologne, Germany
    Clin Neurol Neurosurg 112:137-43. 2010
    ..Predominantly bilateral stimulation of the anterior limb of the internal capsule was utilized...
  16. doi request reprint Basic symptoms in early psychotic and depressive disorders
    Frauke Schultze-Lutter
    University of Cologne, Department of Psychiatry and Psychotherapy, Early Recognition and Intervention Centre for Mental Crises FETZ, 50924 Cologne, Germany
    Br J Psychiatry Suppl 51:s31-7. 2007
    ..Depression is a frequent condition in early psychosis. Therefore, early detection instruments should distinguish depression from beginning psychosis...
  17. ncbi request reprint Intervention in the at-risk state to prevent transition to psychosis
    Stephan Ruhrmann
    Department of Psychiatry and Psychotherapy, University of Cologne, Cologne, Germany
    Curr Opin Psychiatry 22:177-83. 2009
    ..The number of intervention studies aiming to prevent psychosis is still small. Follow-up data of the first studies were published during the last year and neuroprotection has become an important issue...
  18. ncbi request reprint Impaired mismatch negativity generation in prodromal subjects and patients with schizophrenia
    Anke Brockhaus-Dumke
    Department of Psychiatry and Psychotherapy, University of Cologne, Joseph Stelzmann Str 9, D 50924 Cologne, Germany
    Schizophr Res 73:297-310. 2005
    ..To elicit MMN, a three-tone auditory oddball paradigm with 10% 'duration deviants' and 10% 'frequency deviants' was used...
  19. ncbi request reprint Anandamide levels in cerebrospinal fluid of first-episode schizophrenic patients: impact of cannabis use
    F Markus Leweke
    Department of Psychiatry and Psychotherapy, University of Cologne, Kerpener Str 62, 50924 Cologne, Germany
    Schizophr Res 94:29-36. 2007
    ..In the present study we examined whether cannabis use may alter such a mechanism...
  20. pmc Sleep deprivation increases oleoylethanolamide in human cerebrospinal fluid
    Dagmar Koethe
    Department of Psychiatry and Psychotherapy, University of Cologne, 50924, Cologne, Germany
    J Neural Transm 116:301-5. 2009
    ..Thus, our results suggest that oleoylethanolamide release may represent an endogenous neuroprotective signal during sleep deprivation...
  21. pmc Rationale and baseline characteristics of PREVENT: a second-generation intervention trial in subjects at-risk (prodromal) of developing first-episode psychosis evaluating cognitive behavior therapy, aripiprazole, and placebo for the prevention of psychosi
    Andreas Bechdolf
    Department of Psychiatry and Psychotherapy, University of Cologne, Kerpener Str 62, 50924 Cologne, Germany
    Schizophr Bull 37:S111-21. 2011
    ..When the final results of the trial are available, PREVENT will substantially expand the current limited evidence base for best clinical practice in people at-risk (prodromal) of first-episode psychosis...
  22. ncbi request reprint The initial prodrome of schizophrenia: different duration, different underlying deficits?
    Frauke Schultze-Lutter
    Department of Psychiatry and Psychotherapy, University of Cologne, Cologne, Germany
    Compr Psychiatry 48:479-88. 2007
    ....
  23. doi request reprint [The Cologne Early Recognition and Intervention Center for mental crises (FETZ). Evaluation of service use]
    Frauke Schultze-Lutter
    Klinik fur Psychiatrie und Psychotherapie, Universitätsklinik Köln, Früh Erkennungs and Therapie Zentrum für psychische Krisen FETZ, Koln
    Med Klin (Munich) 103:81-9. 2008
    ..Following the German psychopathologic tradition, basic symptoms, especially cognitive-perceptive disturbances, are employed as a means to this aim in addition to the internationally established "ultra-high risk" (UHR) criteria...
  24. ncbi request reprint Cognitive-behavioral therapy in the pre-psychotic phase: an exploratory study
    Andreas Bechdolf
    Cologne Early Recognition and Intervention Centre for Mental Crisis FETZ, Department of Psychiatry and Psychotherapy, University of Cologne, Kerpener Str 62, 50924 Cologne, Germany
    Psychiatry Res 136:251-5. 2005
    ..The specificity of these effects needs to be explored in a controlled trial...
  25. ncbi request reprint Interventions in the initial prodromal states of psychosis in Germany: concept and recruitment
    Andreas Bechdolf
    Early Recognition and Intervention Centre for Mental Crisis FETZ, Department of Psychiatry and Psychotherapy, University of Cologne, Kerpenerstrasse 62, 50924 Cologne, Germany
    Br J Psychiatry Suppl 48:s45-8. 2005
    ..Two intervention strategies are being studied by two large-scale multicentre projects...
  26. ncbi request reprint Neural correlates of visuo-spatial attention during an antisaccade task in schizophrenia: an ERP study
    Indira Tendolkar
    Department of Psychiatry and Psychotherapy, University of Cologne, Cologne, Germany
    Int J Neurosci 115:681-98. 2005
    ..Left temporo-occipitally, this activity was only evident in schizophrenia patients, possibly reflecting additional neuronal recruitment in order to perform the antisaccade task successfully...
  27. ncbi request reprint Recent approaches to psychological interventions for people at risk of psychosis
    Andreas Bechdolf
    Early Recognition and Intervention, Centre for Mental Crises FETZ, Department of Psychiatry and Psychotherapy, University of Cologne, Germany
    Eur Arch Psychiatry Clin Neurosci 256:159-73. 2006
    ....
  28. doi request reprint Probably at-risk, but certainly ill--advocating the introduction of a psychosis spectrum disorder in DSM-V
    Stephan Ruhrmann
    Department of Psychiatry and Psychotherapy, University of Cologne, Cologne, Germany
    Schizophr Res 120:23-37. 2010
    ..Following from this shift in the perception of current at-risk criteria, access to standard medical care would have to be granted, and diagnosis- or symptom- rather than conversion-related interventions would have to be developed...
  29. ncbi request reprint Determinants of subjective quality of life in post acute patients with schizophrenia
    Andreas Bechdolf
    Department of Psychiatry and Psychotherapy, University of Cologne, 50924 Cologne, Germany
    Eur Arch Psychiatry Clin Neurosci 253:228-35. 2003
    ..One could conclude that to enhance patients' QoL, improvements in depressive symptoms, negative coping style, social support and self-efficacy seem to be most effective...
  30. doi request reprint Prediction of psychosis in adolescents and young adults at high risk: results from the prospective European prediction of psychosis study
    Stephan Ruhrmann
    Department of Psychiatry and Psychotherapy, University of Cologne, Kerpener Strasse 62, 50924 Cologne, Germany
    Arch Gen Psychiatry 67:241-51. 2010
    ..Existing criteria need improvement in terms of specificity and individual risk assessment to allow for better targeted and earlier interventions...
  31. doi request reprint Preventing progression to first-episode psychosis in early initial prodromal states
    A Bechdolf
    Department of Psychiatry and Psychotherapy, University of Cologne, Germany
    Br J Psychiatry 200:22-9. 2012
    ....
  32. ncbi request reprint Subjective quality of life in subjects at risk for a first episode of psychosis: a comparison with first episode schizophrenia patients and healthy controls
    Andreas Bechdolf
    Cologne Early Recognition and Intervention Centre for mental crises FETZ, Department of Psychiatry and Psychotherapy, University of Cologne, Kerpener Str 62, 50924 Cologne, Germany
    Schizophr Res 79:137-43. 2005
    ..These findings support the notion that subjects at risk for a first episode of psychosis constitute a clinical population for which further service and intervention research is indicated...
  33. doi request reprint Morphometry of structural disconnectivity indicators in subjects at risk and in age-matched patients with schizophrenia
    Ralf Tepest
    Klinik fur Psychiatrie und Psychotherapie, Uniklinik Köln, Cologne, Germany
    Eur Arch Psychiatry Clin Neurosci 263:15-24. 2013
    ..The results are suggestive for impaired cortico-cortical connections as indicated by gyrification changes in SZ and also in SAR, whereas interhemispherical connectivity at the same time appears to be unaffected...
  34. ncbi request reprint Pharmacological prevention and treatment in clinical at-risk states for psychosis
    Stephan Ruhrmann
    Department of Psychiatry and Psychotherapy, University of Cologne, Germany
    Curr Pharm Des 18:550-7. 2012
    ..Future prevention studies, however, need to solve the challenge of changing immediate transition rates, demanding for new risk enrichment strategies as a prerequisite for feasible trial designs...
  35. doi request reprint Intervention in at-risk states for developing psychosis
    Stephan Ruhrmann
    Department of Psychiatry and Psychotherapy, University of Cologne, Kerpener Strasse 62, 50924 Cologne, Germany
    Eur Arch Psychiatry Clin Neurosci 260:S90-4. 2010
    ..An overview on the current findings and ongoing research in this area is provided...
  36. ncbi request reprint Reliability and validity of Quality of Life assessed by the Short-Form 36 and the Modular System for Quality of Life in patients with schizophrenia and patients with depression
    Ralf Pukrop
    Department of Psychiatry and Psychotherapy, University of Cologne, Joseph Stelzmann Str 9, 50924, Cologne, Germany
    Psychiatry Res 119:63-79. 2003
    ....
  37. ncbi request reprint Evidence for a dysfunctional retrosplenial cortex in patients with schizophrenia: a functional magnetic resonance imaging study with a semantic-perceptual contrast
    Indira Tendolkar
    Department of Psychiatry, University of Cologne, Joseph Stelzmannstr 9, 50924 Cologne, Germany
    Neurosci Lett 369:4-8. 2004
    ..The impaired RS-PCC functionality in a semantic task may relate to verbal memory deficits frequently observed in schizophrenia patients, because this region is pivotal for gating information into the medial temporal lobe memory system...
  38. ncbi request reprint [Frontotemporal dementia]
    Raguna Nagy
    Klinik fur Psychiatrie und Psychotherapie, Universitat zu Koln, Koln
    Med Klin (Munich) 102:816-23. 2007
    ..The estimated prevalence is 15:100,000 in the 45- to 64-year-old population; thus, it appears that the FTD as a cause for so-called presenile dementia is nearly as common as Alzheimer's disease...
  39. ncbi request reprint Antibodies to infectious agents in individuals with recent onset schizophrenia
    F Markus Leweke
    Dept of Psychiatry and Psychotherapy, University of Cologne, Cologne, France
    Eur Arch Psychiatry Clin Neurosci 254:4-8. 2004
    ..These findings indicate that infectious agents may play a role in the etiopathogenesis of some cases of schizophrenia...
  40. doi request reprint Chances and risks of predicting psychosis
    Stephan Ruhrmann
    Department of Psychiatry and Psychotherapy, University of Cologne, 50924 Cologne, Germany
    Eur Arch Psychiatry Clin Neurosci 262:S85-90. 2012
    ..Thus, whether a risk model justifies preventive measures can only be decided by weighing the costs of unnecessary intervention and the benefits of avoiding a potentially devastating outcome...
  41. doi request reprint Neurocognitive indicators of clinical high-risk states for psychosis: a critical review of the evidence
    Ralf Pukrop
    Department of Psychiatry and Psychotherapy, University of Cologne, Kerpener Str 62, 50937, Cologne, Germany
    Neurotox Res 18:272-86. 2010
    ..Finally, some reasons for inconsistent findings are discussed critically speculating on demographic differences, reliability and sample sizes, and conceptual imprecision in communicating results...
  42. ncbi request reprint Dimensions of working memory dysfunction in schizophrenia
    Ralf Pukrop
    Department of Psychiatry and Psychotherapy, University of Cologne, Joseph Stelzmann Str 9, 50928 Cologne, Germany
    Schizophr Res 62:259-68. 2003
    ..Schizophr. Bull. 27 (2001) 157]...
  43. ncbi request reprint Pharmacological intervention in the initial prodromal phase of psychosis
    Stephan Ruhrmann
    Department of Psychiatry and Psychotherapy, University of Cologne, Cologne, Germany
    Eur Psychiatry 20:1-6. 2005
    ..The full benefits of early detection and intervention should be revealed once larger and longer studies are conducted...
  44. ncbi request reprint Self-experienced vulnerability, prodromal symptoms and coping strategies preceding schizophrenic and depressive relapses
    Andreas Bechdolf
    Department of Psychiatry and Psychotherapy, University of Cologne, Joseph Stelzmann Str 9, 50924, Cologne, Germany
    Eur Psychiatry 17:384-93. 2002
    ....
  45. ncbi request reprint [Motivational interviewing for patients with comorbid schizophrenia and substance abuse disorders: a review]
    A Bechdolf
    Klinik für Psychiatrie und Psychotherapie der Universität zu Köln
    Fortschr Neurol Psychiatr 73:728-35. 2005
    ..This may be due to the methodological problems mentioned above or it may be that there is, in fact, no effect. Therefore, there is an urgent need for further research of MI in DD...
  46. doi request reprint Reduced subjective quality of life in persons at risk for psychosis
    S Ruhrmann
    Department of Psychiatry and Psychotherapy, University of Cologne, Cologne, Germany
    Acta Psychiatr Scand 117:357-68. 2008
    ..Subjective quality of life (sQoL) and potentially contributing factors were investigated in individuals putatively in an early (EIPS) or late initial prodromal state (LIPS) and healthy controls (HC)...
  47. doi request reprint Acute effects of treatment for prodromal symptoms for people putatively in a late initial prodromal state of psychosis
    S Ruhrmann
    Department of Psychiatry and Psychotherapy, University Hospital of the University of Cologne, Kerpener Strasse 62, 50924 Cologne, Germany
    Br J Psychiatry Suppl 51:s88-95. 2007
    ..People in a putatively late prodromal state not only have an enhanced risk for psychosis but already suffer from mental and functional disturbances...
  48. ncbi request reprint A randomized comparison of group cognitive-behavioural therapy and group psychoeducation in acute patients with schizophrenia: outcome at 24 months
    A Bechdolf
    Department of Psychiatry and Psychotherapy, University of Cologne, Cologne, Germany
    Acta Psychiatr Scand 112:173-9. 2005
    ..At 6-month follow-up, the CBT group had shown significantly less re-hospitalization rates and on a descriptive level higher compliance with medication...
  49. doi request reprint [Variety of symptoms after drug use of gamma-hydroxybutyric acid (GHB)]
    N Galldiks
    Klinik und Poliklinik fur Neurologie, Uniklinik Köln, Kerpener Strasse 62, Koln
    Fortschr Neurol Psychiatr 79:21-5. 2011
    ..In this review, we summarise current data regarding the history, pharmacodynamics and pharmacokinetics of the drug as well as the relevant symptoms of intoxication or withdrawal as they pertain to neurology and psychiatry...
  50. ncbi request reprint Cannabis-associated psychosis: current status of research
    F Markus Leweke
    Department of Psychiatry and Psychotherapy, University of Cologne, Cologne, Germany
    CNS Drugs 18:895-910. 2004
    ..Long-term psychotherapeutic treatment options involve case management strategies and are mainly based on specialised psychotherapeutic programmes to encourage cannabis users to stop their use of the drug...
  51. ncbi request reprint Neural correlates of temporal context discrimination
    Indira Tendolkar
    Department of Psychiatry, University of Cologne, Joseph Stelzmannstr 9, 50924 Cologne, Germany
    Biol Psychol 66:235-55. 2004
    ..The significance of these old/new effects are discussed in relation to the broader pattern of old/new effects seen in standard tests of declarative memory retrieval...
  52. ncbi request reprint A randomized comparison of group cognitive-behavioural therapy and group psychoeducation in patients with schizophrenia
    A Bechdolf
    Department of Psychiatry and Psychotherapy, University of Cologne, Cologne, Germany
    Acta Psychiatr Scand 110:21-8. 2004
    ..Although the efficacy of cognitive-behavioural therapy (CBT) in schizophrenia has been established in a number of studies, no information is available on the differential efficacy of CBT in comparison with patient psychoeducation (PE)...
  53. doi request reprint Prepulse inhibition of the acoustic startle reflex in high functioning autism
    Sina Kohl
    Department for Psychiatry and Psychotherapy, University Hospital of Cologne, Cologne, North Rhine Westphalia, Germany
    PLoS ONE 9:e92372. 2014
    ..Prepulse inhibition is an operational measure of sensorimotor gating, which indicates an extensive attenuation of the startle reflex that occurs when a startling pulse is preceded by a weaker stimulus, the prepulse...
  54. doi request reprint Personality disorders and accentuations in at-risk persons with and without conversion to first-episode psychosis
    Frauke Schultze-Lutter
    University Hospital of Child and Adolescent Psychiatry, Research Department, Bern, Switzerland
    Early Interv Psychiatry 6:389-98. 2012
    ..The role of PDs and personality accentuations (PAs) in predicting conversion to psychosis was studied in patients symptomatically considered at risk, assuming a major role of the schizotypal subtype...
  55. ncbi request reprint [Is the diagnosis of schizophrenic illness possible in the initial prodromal phase to the first psychotic manifestation?]
    J Klosterkotter
    Klinik und Poliklinik fur Psychiatrie und Psychotherapie, Universitat zu Koln
    Fortschr Neurol Psychiatr 68:S13-21. 2000
    ..Thus in future, an early intervention related to them might enable a prevention of first psychotic episodes...
  56. ncbi request reprint Diagnosing schizophrenia in the initial prodromal phase
    J Klosterkotter
    Department of Psychiatry and Psychotherapy, University of Cologne, Joseph Stelzmann Strasse 9, 50924 Cologne, Germany
    Arch Gen Psychiatry 58:158-64. 2001
    ..In schizophrenia research, early detection in the initial prodrome before first psychotic episodes is a major topic. Therefore, the prognostic accuracy of initial prodromal symptoms was examined prospectively...
  57. ncbi request reprint Early detection and intervention in the initial prodromal phase of schizophrenia
    S Ruhrmann
    Department of Psychiatry and Psychotherapy, University of Cologne, Cologne, Germany
    Pharmacopsychiatry 36:S162-7. 2003
    ..Initial study results targeting an earlier or later prodromal phase are promising, but longer follow-ups and larger samples are needed...
  58. pmc Deep brain stimulation for psychiatric disorders
    Jens Kuhn
    Klinik fur Psychiatrie und Psychotherapie, Klinikum der Universität zu Köln, Germany
    Dtsch Arztebl Int 107:105-13. 2010
    ..In a number of recently published case series, DBS yielded an impressive therapeutic benefit in patients with medically intractable psychiatric diseases...
  59. ncbi request reprint Oxcarbazepine--efficacy and tolerability during treatment of alcohol withdrawal: a double-blind, randomized, placebo-controlled multicenter pilot study
    Dagmar Koethe
    Department of Psychiatry and Psychotherapy, University of Cologne, Cologne, Germany
    Alcohol Clin Exp Res 31:1188-94. 2007
    ..Oxcarbazepine (OXC), a newer anticonvulsive drug, has a favorable safety profile over carbamazepine (CBZ) and other older AEDs due to its excellent efficacy and better side-effect profile...
  60. ncbi request reprint Determination of anandamide and other fatty acyl ethanolamides in human serum by electrospray tandem mass spectrometry
    Daniela Schreiber
    Department of Psychiatry and Psychotherapy, University of Cologne, 50924 Cologne, Germany
    Anal Biochem 361:162-8. 2007
    ..025-25 pmol and for standard PEA and OEA over the range of 0.1-500 pmol. This method provides a time-saving and sensitive alternative to existing methods for the analysis of FAEs in biological samples...
  61. ncbi request reprint Subjective and objective neuropsychological abnormalities in a psychosis prodrome clinic
    Martin Hambrecht
    Department of Psychiatry and Psychotherapy, University of Cologne, Germany
    Br J Psychiatry Suppl 43:s30-7. 2002
    ..Predicting transitions to psychosis is difficult. Neuropsychology might facilitate predictions...
  62. ncbi request reprint The nucleus accumbens: a target for deep brain stimulation in obsessive-compulsive- and anxiety-disorders
    Volker Sturm
    Department of Stereotactic and Functional Neurosurgery, University of Cologne, 50924, Koln, Germany
    J Chem Neuroanat 26:293-9. 2003
    ....
  63. ncbi request reprint Early self-experienced neuropsychological deficits and subsequent schizophrenic diseases: an 8-year average follow-up prospective study
    J Klosterkotter
    Psychiatric Department, University of Cologne, Germany
    Acta Psychiatr Scand 95:396-404. 1997
    ..These findings suggest that certain self-experienced neuropsychological deficits are able to indicate susceptibility to psychosis...
  64. ncbi request reprint Remembering or knowing: electrophysiological evidence for an episodic memory deficit in schizophrenia
    I Tendolkar
    Department of Psychiatry and Psychotherapy, University of Cologne, Germany
    Psychol Med 32:1261-71. 2002
    ..We aimed to disentangle the neural subprocesses leading to this deficit applying the 'Remember/Know procedure'...